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The map label for this gene is mepA [H]

Identifier: 126173580

GI number: 126173580

Start: 1537909

End: 1539264

Strand: Direct

Name: mepA [H]

Synonym: Sbal_1342

Alternate gene names: 126173580

Gene position: 1537909-1539264 (Clockwise)

Preceding gene: 126173578

Following gene: 126173581

Centisome position: 29.99

GC content: 49.63

Gene sequence:

>1356_bases
ATGACAGCAATAACATCTAATCATGCTCCTGCGGATATGAGCCTGCTCGAGGAGCCGATTGCGAAGCTTTTTTGGCGCTA
TACCATACCCACCATTGCCTCTATGTTGGTGACGGGCGTCTATGTGACGATTGATGGCATCTTCGTTGGCCACTATTTGG
GTGAAACTGGGCTGGCGGGGATGATGTTAGCCTATCCAGTCGGCGCTATTTTGTATGCGATTGGCGCCATGATCGGCATG
GGCAGCGCGGCATTAGTGTCGATCAATCTTGGTCAAGGCAATGTGGCTAAGGCCCGTAAATTGCTCGGTAATGCTTTTAG
TTTGTGTTTATTGGCGGGGGCCATTTTTGCCCTCATGGGTGGGATATTCTCGCGGGATATTTTGATCGCCCTCGGGGCGC
AGGGGGATATTCTCGAAAACGCCAACGAATACTTGTTCTGGTATTTCGCCCTGTGTCATTTCCCCATTATTTCAATGACC
TTCACCACATTGCTGCGTAATGACGGTCGGCCATCTATGGTGACTTGGGTGTTGATCTTGGGCGGTGTATTAAACACTTT
CTTAGATTGGCTATTTATTGTGGTCTTCCCCTTTGGTTTAGCGGGCGCTGCGATTGCGACTATGATGTCGCAGGCGGTGA
CTGGGCTTTTGTGTTTGCAGCATTTTTTCAGTCCTCGCACTCAGCTGAGGATCGACCTTGAGCAGATGAAGCTTAAGCTC
GACAATTGCTTGAACATAGCCCGCGTGGGTTTACCCAGCTTTTTGATGAACCTTTATTTATCGATAGTGTTAACCCTACA
CAACACAGCTTTTTTGTGGGTGGGCGGCCCCTTACACGTGGCAGCCTATGGCGTAGTCAGTTACACAGAAGCATTCTTCT
ATCTGATTTTTGAAGGTATCGCCCTCGGCACACAACCCATTTACAGCTTCAATGCGGGCGCTGGGCGTTTCGATAGGGTC
AAGCAGGCACGCAATATTGCCTTTGGTATGACGCTGCTCACCGCTGCCTTGGGCTTAGCGCTGATTTATTCTCGCCCAGA
ATGGTTAGTGTATTTGTTTGCCGGTGATAATCCGAACCTAACGCCCGTGGCGATTGAAGGGATGCATTGGTATTTCTGGG
GCTTACCTATGGAAGGGTTAATCTTAGTCGGTGCGAGTTTCTTCCAAGCAATTAATTGCTCGAAACAAGCCTCTATGCTG
ACCGGCGCGAAACTTATCCTGATCGCTGCGATTATCTACTGCTTCGCTTGGATGTTCGGTGTGATTGGTGTGTGGGTATC
GCTCGCAACCTGTAGCACTATTCTGACGATATGGATGTTCTACGCCATGAAGCGAGTCGAGGCTCGGCTGCAATAA

Upstream 100 bases:

>100_bases
TTACGGCTGATTTTAGGTACAATCCATTGTCGCATTTTTGTTCACCCGATCATTTTTCTAAATAGATACGACTCTTGCCC
CTTTTTTGTGAGAAACGCTA

Downstream 100 bases:

>100_bases
CTCTGTTTTGTTCCAGTCTTGTCTGTGCCTGCTTTTTTGCGTGCGCTGATGATGAGGGAAGAGGGCAAAAGAAGGCAAAA
TAAGCGACCAGACAAGCGGG

Product: multi anti extrusion protein MatE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTAITSNHAPADMSLLEEPIAKLFWRYTIPTIASMLVTGVYVTIDGIFVGHYLGETGLAGMMLAYPVGAILYAIGAMIGM
GSAALVSINLGQGNVAKARKLLGNAFSLCLLAGAIFALMGGIFSRDILIALGAQGDILENANEYLFWYFALCHFPIISMT
FTTLLRNDGRPSMVTWVLILGGVLNTFLDWLFIVVFPFGLAGAAIATMMSQAVTGLLCLQHFFSPRTQLRIDLEQMKLKL
DNCLNIARVGLPSFLMNLYLSIVLTLHNTAFLWVGGPLHVAAYGVVSYTEAFFYLIFEGIALGTQPIYSFNAGAGRFDRV
KQARNIAFGMTLLTAALGLALIYSRPEWLVYLFAGDNPNLTPVAIEGMHWYFWGLPMEGLILVGASFFQAINCSKQASML
TGAKLILIAAIIYCFAWMFGVIGVWVSLATCSTILTIWMFYAMKRVEARLQ

Sequences:

>Translated_451_residues
MTAITSNHAPADMSLLEEPIAKLFWRYTIPTIASMLVTGVYVTIDGIFVGHYLGETGLAGMMLAYPVGAILYAIGAMIGM
GSAALVSINLGQGNVAKARKLLGNAFSLCLLAGAIFALMGGIFSRDILIALGAQGDILENANEYLFWYFALCHFPIISMT
FTTLLRNDGRPSMVTWVLILGGVLNTFLDWLFIVVFPFGLAGAAIATMMSQAVTGLLCLQHFFSPRTQLRIDLEQMKLKL
DNCLNIARVGLPSFLMNLYLSIVLTLHNTAFLWVGGPLHVAAYGVVSYTEAFFYLIFEGIALGTQPIYSFNAGAGRFDRV
KQARNIAFGMTLLTAALGLALIYSRPEWLVYLFAGDNPNLTPVAIEGMHWYFWGLPMEGLILVGASFFQAINCSKQASML
TGAKLILIAAIIYCFAWMFGVIGVWVSLATCSTILTIWMFYAMKRVEARLQ
>Mature_450_residues
TAITSNHAPADMSLLEEPIAKLFWRYTIPTIASMLVTGVYVTIDGIFVGHYLGETGLAGMMLAYPVGAILYAIGAMIGMG
SAALVSINLGQGNVAKARKLLGNAFSLCLLAGAIFALMGGIFSRDILIALGAQGDILENANEYLFWYFALCHFPIISMTF
TTLLRNDGRPSMVTWVLILGGVLNTFLDWLFIVVFPFGLAGAAIATMMSQAVTGLLCLQHFFSPRTQLRIDLEQMKLKLD
NCLNIARVGLPSFLMNLYLSIVLTLHNTAFLWVGGPLHVAAYGVVSYTEAFFYLIFEGIALGTQPIYSFNAGAGRFDRVK
QARNIAFGMTLLTAALGLALIYSRPEWLVYLFAGDNPNLTPVAIEGMHWYFWGLPMEGLILVGASFFQAINCSKQASMLT
GAKLILIAAIIYCFAWMFGVIGVWVSLATCSTILTIWMFYAMKRVEARLQ

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49308; Mature: 49177

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAITSNHAPADMSLLEEPIAKLFWRYTIPTIASMLVTGVYVTIDGIFVGHYLGETGLAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCHHH
MMLAYPVGAILYAIGAMIGMGSAALVSINLGQGNVAKARKLLGNAFSLCLLAGAIFALMG
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIFSRDILIALGAQGDILENANEYLFWYFALCHFPIISMTFTTLLRNDGRPSMVTWVLIL
HHHHCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GGVLNTFLDWLFIVVFPFGLAGAAIATMMSQAVTGLLCLQHFFSPRTQLRIDLEQMKLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHH
DNCLNIARVGLPSFLMNLYLSIVLTLHNTAFLWVGGPLHVAAYGVVSYTEAFFYLIFEGI
HHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
ALGTQPIYSFNAGAGRFDRVKQARNIAFGMTLLTAALGLALIYSRPEWLVYLFAGDNPNL
HCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
TPVAIEGMHWYFWGLPMEGLILVGASFFQAINCSKQASMLTGAKLILIAAIIYCFAWMFG
CEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGVWVSLATCSTILTIWMFYAMKRVEARLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAITSNHAPADMSLLEEPIAKLFWRYTIPTIASMLVTGVYVTIDGIFVGHYLGETGLAG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCHHH
MMLAYPVGAILYAIGAMIGMGSAALVSINLGQGNVAKARKLLGNAFSLCLLAGAIFALMG
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GIFSRDILIALGAQGDILENANEYLFWYFALCHFPIISMTFTTLLRNDGRPSMVTWVLIL
HHHHCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GGVLNTFLDWLFIVVFPFGLAGAAIATMMSQAVTGLLCLQHFFSPRTQLRIDLEQMKLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHH
DNCLNIARVGLPSFLMNLYLSIVLTLHNTAFLWVGGPLHVAAYGVVSYTEAFFYLIFEGI
HHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
ALGTQPIYSFNAGAGRFDRVKQARNIAFGMTLLTAALGLALIYSRPEWLVYLFAGDNPNL
HCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
TPVAIEGMHWYFWGLPMEGLILVGASFFQAINCSKQASMLTGAKLILIAAIIYCFAWMFG
CEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGVWVSLATCSTILTIWMFYAMKRVEARLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA