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The map label for this gene is yjcE [H]

Identifier: 126173457

GI number: 126173457

Start: 1400146

End: 1401450

Strand: Direct

Name: yjcE [H]

Synonym: Sbal_1219

Alternate gene names: 126173457

Gene position: 1400146-1401450 (Clockwise)

Preceding gene: 126173456

Following gene: 126173460

Centisome position: 27.31

GC content: 45.44

Gene sequence:

>1305_bases
ATGTCCAGTTACCAAATTCTGTGTATCCTCTGCGCCTTGGCGCTAGTCACTTCGGTTGTCTCTTCACGCGTCCATAAACT
GCAGGAAACTGTGGCCATTACGGCTATCGCCCTAGGCATGAGTTTGTTATTACTCCTAGGGGGAAAGGCCTTAGGCGGGC
ATGTTTATCTGTATTTTGTATCAGGCTTAGAGAAGCTTGATTTTCAAGCCTTGCTGCTCAATGGCATGTTAGGTTTTTTA
CTCTTTGCCGGCGCATTGCAGATCCGTTTAAAAATACTGAGGCATCAGAAGTGGGAGATTTTAATCCTCGCCTTTGTCAG
CACTTTATTATCGACCTTTATCATAGGAGGACTGTTATTTTGGGTCGCGCCTATGTTGGGTCTACCGTTACAGCTTAGCC
ACTGCTTGTTGTTTGGCGCCTTAATTTCGCCAACCGATCCCATTGCCGTTTTGGCTATTTTAAAGAAAATGGGCGCACCG
GAAGATATTGCTATCCAAGTTGAAGGTGAATCTTTATTTAACGATGGCATAGGGTTAGTGATTTTTGTGGCAATATCGCA
ATTAGCCTTCTCTACTGAACCGCTGACGTTTATTCATATCTCTGAGTTATTTATTCGTGAGGCGGTAGGCGGGGTTATTT
ATGGTGGCGTTCTTGGTTTTCTGTTGCATCATTTTTTCCGCTATTGCGAGGAAGAAACGCAATTGATGTTGGTCACTTTG
CTGATCCCAACCGCGGGATACGTGATGGCGGAAGTGTTTGGGGTTTCTGGGCCTTTAGCTATGGTGAGTGCAGGTATCAT
CATAGGTAATTTCAGTGTGCCTAAGTTTTTTGCCCGCCACGAGCGAGTGAAACTACTGACATTTTGGTCGCTGATTGAAT
CTTTCTTCAATGCATTACTTTTCCTACTACTCGGCTTACTGCTTTTGTTAGTCACTTTTAAAGCGCCATTGTGGTGGTTT
ATGTTTGTGGCTATTCCACTGGTGTTATTGGCGCGTGCCGTGAGTGTGATATTACCTTATATGGGCTTTAGGTTGTTTAA
GTCTTACAACCCCTATGCAGAGACGATTCTGATTTGGGGGGGGTTAAGGGGAGGATTAGCACTCGCGATGGCAATGAGTT
TACCTGAGGGGATAGTCATCGATGCTATTGGTGGTGTGGAGCTGCGGGAATTATTGTTAGTGATGACCTATGCCGTCGTC
GTATTTTCGATTCTAGTGCAGGGCTCTACTATGACAGGGCTTATCCGCAGGAGTAATGCCGTTACCGAACCATCGAGGGC
TGTCTGCTCTTCTGAAAATGCATAA

Upstream 100 bases:

>100_bases
TTTTGCCACAGGATCATTAAAGGGTGGTTAAGTCTATTGGATGGTTTAGAAATCTAAACTTGTGCTAGAGTCTCTAAATT
GATGATTTTTAGAGGCTCTT

Downstream 100 bases:

>100_bases
AGGATGATTTGTCGCGATAGTAAACAATATTAAGCCTGCTAGTCATCACGCTGACTTGCAGGCTTATTTCAGTCAATCAG
GGATAAAAGAAGTCTCATTT

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFVSGLEKLDFQALLLNGMLGFL
LFAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLFWVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAP
EDIAIQVEGESLFNDGIGLVIFVAISQLAFSTEPLTFIHISELFIREAVGGVIYGGVLGFLLHHFFRYCEEETQLMLVTL
LIPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARHERVKLLTFWSLIESFFNALLFLLLGLLLLLVTFKAPLWWF
MFVAIPLVLLARAVSVILPYMGFRLFKSYNPYAETILIWGGLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVV
VFSILVQGSTMTGLIRRSNAVTEPSRAVCSSENA

Sequences:

>Translated_434_residues
MSSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFVSGLEKLDFQALLLNGMLGFL
LFAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLFWVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAP
EDIAIQVEGESLFNDGIGLVIFVAISQLAFSTEPLTFIHISELFIREAVGGVIYGGVLGFLLHHFFRYCEEETQLMLVTL
LIPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARHERVKLLTFWSLIESFFNALLFLLLGLLLLLVTFKAPLWWF
MFVAIPLVLLARAVSVILPYMGFRLFKSYNPYAETILIWGGLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVV
VFSILVQGSTMTGLIRRSNAVTEPSRAVCSSENA
>Mature_433_residues
SSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFVSGLEKLDFQALLLNGMLGFLL
FAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLFWVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAPE
DIAIQVEGESLFNDGIGLVIFVAISQLAFSTEPLTFIHISELFIREAVGGVIYGGVLGFLLHHFFRYCEEETQLMLVTLL
IPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARHERVKLLTFWSLIESFFNALLFLLLGLLLLLVTFKAPLWWFM
FVAIPLVLLARAVSVILPYMGFRLFKSYNPYAETILIWGGLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVVV
FSILVQGSTMTGLIRRSNAVTEPSRAVCSSENA

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI148727259, Length=292, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI15529998, Length=344, Percent_Identity=26.453488372093, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI27734935, Length=406, Percent_Identity=22.4137931034483, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI14211919, Length=451, Percent_Identity=25.4988913525499, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI27777632, Length=343, Percent_Identity=28.2798833819242, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI294997330, Length=380, Percent_Identity=24.2105263157895, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI110227626, Length=380, Percent_Identity=24.2105263157895, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI5454070, Length=362, Percent_Identity=24.8618784530387, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI194239733, Length=336, Percent_Identity=26.4880952380952, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI41872703, Length=335, Percent_Identity=25.6716417910448, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790501, Length=200, Percent_Identity=35.5, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71999819, Length=329, Percent_Identity=25.2279635258359, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71999817, Length=329, Percent_Identity=25.2279635258359, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71999821, Length=329, Percent_Identity=25.2279635258359, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71987535, Length=370, Percent_Identity=25.1351351351351, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71987537, Length=370, Percent_Identity=25.1351351351351, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71980847, Length=335, Percent_Identity=27.7611940298507, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71990924, Length=328, Percent_Identity=26.5243902439024, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71990932, Length=328, Percent_Identity=25.609756097561, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71992101, Length=352, Percent_Identity=20.7386363636364, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71992107, Length=354, Percent_Identity=20.9039548022599, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25150332, Length=329, Percent_Identity=22.7963525835866, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147678, Length=316, Percent_Identity=23.7341772151899, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221510740, Length=337, Percent_Identity=26.7062314540059, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221510734, Length=349, Percent_Identity=26.0744985673352, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221510738, Length=354, Percent_Identity=25.4237288135593, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221510736, Length=341, Percent_Identity=26.099706744868, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221510732, Length=341, Percent_Identity=26.099706744868, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24585580, Length=341, Percent_Identity=26.099706744868, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24585578, Length=341, Percent_Identity=26.099706744868, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281360447, Length=363, Percent_Identity=28.3746556473829, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281364513, Length=369, Percent_Identity=24.1192411924119, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221473215, Length=369, Percent_Identity=24.1192411924119, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221473222, Length=369, Percent_Identity=24.1192411924119, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221473212, Length=369, Percent_Identity=24.1192411924119, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 47288; Mature: 47157

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEH
SGLEKLDFQALLLNGMLGFLLFAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLF
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAPEDIAIQVEGESLFNDGIGLV
HHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHCCHHHH
IFVAISQLAFSTEPLTFIHISELFIREAVGGVIYGGVLGFLLHHFFRYCEEETQLMLVTL
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LIPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARHERVKLLTFWSLIESFFNALL
HHHCCHHHHHHHHCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLLGLLLLLVTFKAPLWWFMFVAIPLVLLARAVSVILPYMGFRLFKSYNPYAETILIWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEC
GLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVVVFSILVQGSTMTGLIRRSNA
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
VTEPSRAVCSSENA
CCCCHHHHHCCCCC
>Mature Secondary Structure 
SSYQILCILCALALVTSVVSSRVHKLQETVAITAIALGMSLLLLLGGKALGGHVYLYFV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEH
SGLEKLDFQALLLNGMLGFLLFAGALQIRLKILRHQKWEILILAFVSTLLSTFIIGGLLF
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WVAPMLGLPLQLSHCLLFGALISPTDPIAVLAILKKMGAPEDIAIQVEGESLFNDGIGLV
HHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCHHHHCCHHHH
IFVAISQLAFSTEPLTFIHISELFIREAVGGVIYGGVLGFLLHHFFRYCEEETQLMLVTL
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LIPTAGYVMAEVFGVSGPLAMVSAGIIIGNFSVPKFFARHERVKLLTFWSLIESFFNALL
HHHCCHHHHHHHHCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLLGLLLLLVTFKAPLWWFMFVAIPLVLLARAVSVILPYMGFRLFKSYNPYAETILIWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEC
GLRGGLALAMAMSLPEGIVIDAIGGVELRELLLVMTYAVVVFSILVQGSTMTGLIRRSNA
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
VTEPSRAVCSSENA
CCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]