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The map label for this gene is ygjG [C]

Identifier: 126173334

GI number: 126173334

Start: 1258162

End: 1259526

Strand: Reverse

Name: ygjG [C]

Synonym: Sbal_1092

Alternate gene names: 126173334

Gene position: 1259526-1258162 (Counterclockwise)

Preceding gene: 126173344

Following gene: 126173333

Centisome position: 24.56

GC content: 49.6

Gene sequence:

>1365_bases
ATGGCCGATTTGCCGCTCAATTCCTCAAGTGATGCTTCACATCAATCTTCAACTGAGCATCCCTCACTTGAACATTTCTG
GATGCCTTTTACCGCCAACCGCCAATTCAAAGCCAACCCGCGGTTACTCACCAAAGCGGAAGGCATGTATTACACGGATA
TTGATGGCAATAAGGTATTAGATGCTACCGCCGGTTTATGGTGTTGTAACGCAGGCCATGGTCGCAAAGAAATCAGCGAA
GCAGTCAGCAAACAAATTAAAGAGATGGACTACGCGCCCTCCTTCCAAATGGGTCACCCTATCGCCTTTGAACTTGCCGA
GCGCTTAGTCGAGCTCAGTCCTGAAGGATTAAACAAAGTCTTCTTTACTAACTCAGGTTCTGAGTCCGTCGATACAGCAC
TTAAGATGGCACTTTGCTATCACAGAGCCAACGGCCAAGCCTCACGCACTCGCTTTATTGGGCGCGAAATGGGTTACCAC
GGTGTCGGCTTTGGCGGCATCTCTGTGGGTGGGTTAAGCAATAACCGCAAAGCATTTAGCGGCCAATTACTGCAGGGTGT
CGATCACTTACCTCATACCTTAGATATCCAAAATGCGGCATTTACCCGTGGACTCTCACACTTTGGCGCTGAAAAAGCCG
AGGTATTAGAACAGCTTGTTACCCTGCATGGCGCCGAAAATATTGCCGCCGTAATCGTTGAACCAATGTCGGGTTCAGCA
GGGGTGATATTGCCGCCACAAGGTTACTTAAAACGTCTGCGTGAAATCACTAAAAAGCATGGCATCCTACTAATTTTTGA
TGAAGTCATCACCGCTTTTGGCCGCGTTGGCGCCGCCTTTGCGAGTCAGCGTTGGGGCGTTATTCCAGACATTATCACCA
CGGCTAAAGCCATCAATAACGGTGCGATTCCTATGGGCGCAGTGTTTGTGCAAGATTTTATCCACGACACTTGCATGCAA
GGCTCTAATGAACTGATTGAGTTCTTCCACGGCTACACCTATTCCGGTCATCCAGTGGCTGCAGCGGCCGCACTTGCCAC
CCTATCGATTTATGAGAATGAGCAATTATTCGAGCGCAGCTTTGAGCTTGAGCGCTACTTTGAAGATGCCGTGCACAGCC
TCAAAGGGTTGCCGAATGTGATTGATATTCGCAACACAGGGCTAGTCGCTGGGATTCAATTCTCCCCTAACGCTCAAGGC
GCGGGTAAACGGGGTTACGGCGTGTTTGAACACTGCTTCCGCCACGGCACTTTAGTGCGAGCCACGGGCGACATTATTGC
CATGTCACCACCACTGATTGTCGATAAACGCGAGATAGACCAAATGGTTAATAGCCTAAGCGATGCCATTAACGCCGTTG
GATAA

Upstream 100 bases:

>100_bases
AACTGCACACAGCTCTTCCATGTTCATTATTTCTAACATAGCATAGCAAATATTAGCCACCCTAAAACAAGACCTGAAAA
TACAGGACAAGGTAGACACT

Downstream 100 bases:

>100_bases
TAGCGCCAGCTGTTCGTTCCACTCTCACATTTAACACCCCGCTGCGGCGGGGAACATCAAAGGTTAACTATGCTCAAGAT
CACTCACTTTGTTAATGGTC

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MADLPLNSSSDASHQSSTEHPSLEHFWMPFTANRQFKANPRLLTKAEGMYYTDIDGNKVLDATAGLWCCNAGHGRKEISE
AVSKQIKEMDYAPSFQMGHPIAFELAERLVELSPEGLNKVFFTNSGSESVDTALKMALCYHRANGQASRTRFIGREMGYH
GVGFGGISVGGLSNNRKAFSGQLLQGVDHLPHTLDIQNAAFTRGLSHFGAEKAEVLEQLVTLHGAENIAAVIVEPMSGSA
GVILPPQGYLKRLREITKKHGILLIFDEVITAFGRVGAAFASQRWGVIPDIITTAKAINNGAIPMGAVFVQDFIHDTCMQ
GSNELIEFFHGYTYSGHPVAAAAALATLSIYENEQLFERSFELERYFEDAVHSLKGLPNVIDIRNTGLVAGIQFSPNAQG
AGKRGYGVFEHCFRHGTLVRATGDIIAMSPPLIVDKREIDQMVNSLSDAINAVG

Sequences:

>Translated_454_residues
MADLPLNSSSDASHQSSTEHPSLEHFWMPFTANRQFKANPRLLTKAEGMYYTDIDGNKVLDATAGLWCCNAGHGRKEISE
AVSKQIKEMDYAPSFQMGHPIAFELAERLVELSPEGLNKVFFTNSGSESVDTALKMALCYHRANGQASRTRFIGREMGYH
GVGFGGISVGGLSNNRKAFSGQLLQGVDHLPHTLDIQNAAFTRGLSHFGAEKAEVLEQLVTLHGAENIAAVIVEPMSGSA
GVILPPQGYLKRLREITKKHGILLIFDEVITAFGRVGAAFASQRWGVIPDIITTAKAINNGAIPMGAVFVQDFIHDTCMQ
GSNELIEFFHGYTYSGHPVAAAAALATLSIYENEQLFERSFELERYFEDAVHSLKGLPNVIDIRNTGLVAGIQFSPNAQG
AGKRGYGVFEHCFRHGTLVRATGDIIAMSPPLIVDKREIDQMVNSLSDAINAVG
>Mature_453_residues
ADLPLNSSSDASHQSSTEHPSLEHFWMPFTANRQFKANPRLLTKAEGMYYTDIDGNKVLDATAGLWCCNAGHGRKEISEA
VSKQIKEMDYAPSFQMGHPIAFELAERLVELSPEGLNKVFFTNSGSESVDTALKMALCYHRANGQASRTRFIGREMGYHG
VGFGGISVGGLSNNRKAFSGQLLQGVDHLPHTLDIQNAAFTRGLSHFGAEKAEVLEQLVTLHGAENIAAVIVEPMSGSAG
VILPPQGYLKRLREITKKHGILLIFDEVITAFGRVGAAFASQRWGVIPDIITTAKAINNGAIPMGAVFVQDFIHDTCMQG
SNELIEFFHGYTYSGHPVAAAAALATLSIYENEQLFERSFELERYFEDAVHSLKGLPNVIDIRNTGLVAGIQFSPNAQGA
GKRGYGVFEHCFRHGTLVRATGDIIAMSPPLIVDKREIDQMVNSLSDAINAVG

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=419, Percent_Identity=27.6849642004773, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI13994255, Length=445, Percent_Identity=26.9662921348315, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI37574042, Length=428, Percent_Identity=27.803738317757, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226442705, Length=428, Percent_Identity=28.0373831775701, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI284507298, Length=335, Percent_Identity=28.3582089552239, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=28.3163265306122, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI24119277, Length=368, Percent_Identity=26.3586956521739, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI145693181, Length=407, Percent_Identity=30.4668304668305, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1786991, Length=429, Percent_Identity=30.0699300699301, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789759, Length=444, Percent_Identity=27.4774774774775, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1788044, Length=412, Percent_Identity=26.4563106796117, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1787560, Length=439, Percent_Identity=26.6514806378132, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789016, Length=358, Percent_Identity=27.9329608938547, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786349, Length=371, Percent_Identity=28.3018867924528, Blast_Score=99, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI32564660, Length=451, Percent_Identity=29.9334811529933, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI25144271, Length=415, Percent_Identity=27.710843373494, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=26.1467889908257, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144274, Length=222, Percent_Identity=34.6846846846847, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323470, Length=432, Percent_Identity=26.6203703703704, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6324386, Length=361, Percent_Identity=29.3628808864266, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324432, Length=415, Percent_Identity=25.3012048192771, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI161085790, Length=480, Percent_Identity=27.5, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21357415, Length=418, Percent_Identity=27.0334928229665, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI28574759, Length=480, Percent_Identity=27.5, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI21356575, Length=438, Percent_Identity=27.1689497716895, Blast_Score=136, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 49368; Mature: 49236

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLPLNSSSDASHQSSTEHPSLEHFWMPFTANRQFKANPRLLTKAEGMYYTDIDGNKVL
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCEEEEECCCCEEE
DATAGLWCCNAGHGRKEISEAVSKQIKEMDYAPSFQMGHPIAFELAERLVELSPEGLNKV
ECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
FFTNSGSESVDTALKMALCYHRANGQASRTRFIGREMGYHGVGFGGISVGGLSNNRKAFS
EEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHH
GQLLQGVDHLPHTLDIQNAAFTRGLSHFGAEKAEVLEQLVTLHGAENIAAVIVEPMSGSA
HHHHHHHHHCCCEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
GVILPPQGYLKRLREITKKHGILLIFDEVITAFGRVGAAFASQRWGVIPDIITTAKAINN
CEEECCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
GAIPMGAVFVQDFIHDTCMQGSNELIEFFHGYTYSGHPVAAAAALATLSIYENEQLFERS
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
FELERYFEDAVHSLKGLPNVIDIRNTGLVAGIQFSPNAQGAGKRGYGVFEHCFRHGTLVR
HHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCEEE
ATGDIIAMSPPLIVDKREIDQMVNSLSDAINAVG
ECCCEEEECCCCEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADLPLNSSSDASHQSSTEHPSLEHFWMPFTANRQFKANPRLLTKAEGMYYTDIDGNKVL
CCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCEEEEECCCCEEE
DATAGLWCCNAGHGRKEISEAVSKQIKEMDYAPSFQMGHPIAFELAERLVELSPEGLNKV
ECCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
FFTNSGSESVDTALKMALCYHRANGQASRTRFIGREMGYHGVGFGGISVGGLSNNRKAFS
EEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHH
GQLLQGVDHLPHTLDIQNAAFTRGLSHFGAEKAEVLEQLVTLHGAENIAAVIVEPMSGSA
HHHHHHHHHCCCEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
GVILPPQGYLKRLREITKKHGILLIFDEVITAFGRVGAAFASQRWGVIPDIITTAKAINN
CEEECCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
GAIPMGAVFVQDFIHDTCMQGSNELIEFFHGYTYSGHPVAAAAALATLSIYENEQLFERS
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHH
FELERYFEDAVHSLKGLPNVIDIRNTGLVAGIQFSPNAQGAGKRGYGVFEHCFRHGTLVR
HHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCEEE
ATGDIIAMSPPLIVDKREIDQMVNSLSDAINAVG
ECCCEEEECCCCEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]