Click here to switch to the map view.

The map label for this gene is ndh [H]

Identifier: 126173313

GI number: 126173313

Start: 1230239

End: 1231528

Strand: Direct

Name: ndh [H]

Synonym: Sbal_1070

Alternate gene names: 126173313

Gene position: 1230239-1231528 (Clockwise)

Preceding gene: 126173312

Following gene: 126173315

Centisome position: 23.99

GC content: 44.03

Gene sequence:

>1290_bases
ATGACCGGTAAAAGAATTGTTATTGTCGGTGGTGGTGCGGGAGGGTTAGCCTTAGCATCAAAACTTGGGCGAAAACTGGG
TCATAAGCAAGGGTTCGACATTTGTTTAGTCGACAGAAGTCCTATTCACATCTGGAAACCCAAATTACATGAAGTTGCTG
TTGGGGTCATTGATCAATCTCTCGATGGTTTACTTTACCGCGATCACGGCCTAAAAAATGGTTATCGCTATGTCCGCGGT
GAGATTGAAGGCTGCGATCCATCGGGCAAAACGATCCAATTGGCACCTGTTTACAGTGACGATGGTGAATTATTACTTGC
TGATCGTGCTCTGTCTTATGATTATCTTGTGCTGGCATTAGGCAGTGTATCGAATACCTTTAATACCAAGGGCGCCGAAG
AAAACTGCATATTTCTTGATAGTTTAGAAAATGCTGAACGATTTCATCATAAGTTACTTGATGCCTTGCTGCAGTTAAAT
GAATCTCAAGGTAAATTGAGCATTGGTATTGTGGGCGCGGGTGCGACGGGTGTTGAACTTGCCGCCGAGCTGCATCATGT
TATCGAGTCAGTAAAAGAATACGGTTATCTAAACATTTCTAAGCATCATCTCGATGTGCATCTTATTGAAGCCTCTCCAA
AAATTTTACCCCAGTTACCTGAGAAGGTGAGTGCACGTGCGCAGTCCGTATTGGATAAAATAGGGATTAAACTGCATTTA
GGTGTACAGGTAAAAGAAGTCACGGTGCAAGGTTTTGTCACGCCCGATGGCGATGTTATCGAAGCCAGTTTAAAGGTGTG
GGCTGCCGGCGTTAAAGGGCCTGCGGTATGCGCAAAATTTACCTCGTTGCCGATCACGCCACGTAATCAAATTGATGTCG
ATGCGTGCATGAGAGTTAAAGGACAAGAGGATATTTATGCGATTGGTGATTGCGCGGCGCTCATTTTAGAGAATGGTAAA
GCTGTACCGCCACGGGCTCAATCAGCCGATCAAATGGCTGATAGATTGTATAAGAACATTGTTAATCGTTTGCAAGACAA
AGCTGAGTTGCCGTTTGTGTATAAAGATTACGGCTCGTTAGTATCGTTAAGCCGTTTTTCTGCGGTGGGCAATTTGATGG
GTAATTTGCGTTCTGGTGACTTTTTTATCGAAGGGCATGTAGCACGCTTGATGTACGTGTCGTTGTATCAACGACATTTA
GGTAGTTTATATGGTTGGTTTTCGGCATTAATCTATCGACTCGCACAAAAGCTACTGCGCTGGCACAGGCCTAAATTAAA
ACTGCATTAA

Upstream 100 bases:

>100_bases
ACGCTAGATGCTGTAGCCGCTAAAGTAGTTTTCTCTTAATGAAATCGTGGTATAAGGTACAAAGCGTGGTTCTGTATATT
TATCAGTGAGTGAGGATGTT

Downstream 100 bases:

>100_bases
GTCACTGGCTTTATATAACAAAAACGCACTCAATCGAGTGCGTTTTTTTGTCTCTCAACATTGCTTATTTGTGCGGCACC
GCGGAAGAGTCGCGAATCAC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTGKRIVIVGGGAGGLALASKLGRKLGHKQGFDICLVDRSPIHIWKPKLHEVAVGVIDQSLDGLLYRDHGLKNGYRYVRG
EIEGCDPSGKTIQLAPVYSDDGELLLADRALSYDYLVLALGSVSNTFNTKGAEENCIFLDSLENAERFHHKLLDALLQLN
ESQGKLSIGIVGAGATGVELAAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPEKVSARAQSVLDKIGIKLHL
GVQVKEVTVQGFVTPDGDVIEASLKVWAAGVKGPAVCAKFTSLPITPRNQIDVDACMRVKGQEDIYAIGDCAALILENGK
AVPPRAQSADQMADRLYKNIVNRLQDKAELPFVYKDYGSLVSLSRFSAVGNLMGNLRSGDFFIEGHVARLMYVSLYQRHL
GSLYGWFSALIYRLAQKLLRWHRPKLKLH

Sequences:

>Translated_429_residues
MTGKRIVIVGGGAGGLALASKLGRKLGHKQGFDICLVDRSPIHIWKPKLHEVAVGVIDQSLDGLLYRDHGLKNGYRYVRG
EIEGCDPSGKTIQLAPVYSDDGELLLADRALSYDYLVLALGSVSNTFNTKGAEENCIFLDSLENAERFHHKLLDALLQLN
ESQGKLSIGIVGAGATGVELAAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPEKVSARAQSVLDKIGIKLHL
GVQVKEVTVQGFVTPDGDVIEASLKVWAAGVKGPAVCAKFTSLPITPRNQIDVDACMRVKGQEDIYAIGDCAALILENGK
AVPPRAQSADQMADRLYKNIVNRLQDKAELPFVYKDYGSLVSLSRFSAVGNLMGNLRSGDFFIEGHVARLMYVSLYQRHL
GSLYGWFSALIYRLAQKLLRWHRPKLKLH
>Mature_428_residues
TGKRIVIVGGGAGGLALASKLGRKLGHKQGFDICLVDRSPIHIWKPKLHEVAVGVIDQSLDGLLYRDHGLKNGYRYVRGE
IEGCDPSGKTIQLAPVYSDDGELLLADRALSYDYLVLALGSVSNTFNTKGAEENCIFLDSLENAERFHHKLLDALLQLNE
SQGKLSIGIVGAGATGVELAAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPEKVSARAQSVLDKIGIKLHLG
VQVKEVTVQGFVTPDGDVIEASLKVWAAGVKGPAVCAKFTSLPITPRNQIDVDACMRVKGQEDIYAIGDCAALILENGKA
VPPRAQSADQMADRLYKNIVNRLQDKAELPFVYKDYGSLVSLSRFSAVGNLMGNLRSGDFFIEGHVARLMYVSLYQRHLG
SLYGWFSALIYRLAQKLLRWHRPKLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=429, Percent_Identity=46.1538461538462, Blast_Score=368, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6323515, Length=464, Percent_Identity=25.2155172413793, Blast_Score=109, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6320118, Length=444, Percent_Identity=28.6036036036036, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323794, Length=329, Percent_Identity=29.1793313069909, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47059; Mature: 46928

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKRIVIVGGGAGGLALASKLGRKLGHKQGFDICLVDRSPIHIWKPKLHEVAVGVIDQS
CCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHH
LDGLLYRDHGLKNGYRYVRGEIEGCDPSGKTIQLAPVYSDDGELLLADRALSYDYLVLAL
HCCEEEECCCCCCCCEEEECEECCCCCCCCEEEEEEEECCCCCEEEEECCCCCCEEEEEE
GSVSNTFNTKGAEENCIFLDSLENAERFHHKLLDALLQLNESQGKLSIGIVGAGATGVEL
CCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHH
AAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPEKVSARAQSVLDKIGIKLHL
HHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCHHHCCHHHHHHHHHHHHHHCCCEEEE
GVQVKEVTVQGFVTPDGDVIEASLKVWAAGVKGPAVCAKFTSLPITPRNQIDVDACMRVK
CEEEEEEEEEEEECCCCCHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHCCC
GQEDIYAIGDCAALILENGKAVPPRAQSADQMADRLYKNIVNRLQDKAELPFVYKDYGSL
CCCCEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHH
VSLSRFSAVGNLMGNLRSGDFFIEGHVARLMYVSLYQRHLGSLYGWFSALIYRLAQKLLR
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WHRPKLKLH
HCCCCCCCC
>Mature Secondary Structure 
TGKRIVIVGGGAGGLALASKLGRKLGHKQGFDICLVDRSPIHIWKPKLHEVAVGVIDQS
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHHH
LDGLLYRDHGLKNGYRYVRGEIEGCDPSGKTIQLAPVYSDDGELLLADRALSYDYLVLAL
HCCEEEECCCCCCCCEEEECEECCCCCCCCEEEEEEEECCCCCEEEEECCCCCCEEEEEE
GSVSNTFNTKGAEENCIFLDSLENAERFHHKLLDALLQLNESQGKLSIGIVGAGATGVEL
CCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHH
AAELHHVIESVKEYGYLNISKHHLDVHLIEASPKILPQLPEKVSARAQSVLDKIGIKLHL
HHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCHHHCCHHHHHHHHHHHHHHCCCEEEE
GVQVKEVTVQGFVTPDGDVIEASLKVWAAGVKGPAVCAKFTSLPITPRNQIDVDACMRVK
CEEEEEEEEEEEECCCCCHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHCCC
GQEDIYAIGDCAALILENGKAVPPRAQSADQMADRLYKNIVNRLQDKAELPFVYKDYGSL
CCCCEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHH
VSLSRFSAVGNLMGNLRSGDFFIEGHVARLMYVSLYQRHLGSLYGWFSALIYRLAQKLLR
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WHRPKLKLH
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]