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The map label for this gene is oadA [H]

Identifier: 126173269

GI number: 126173269

Start: 1178251

End: 1180071

Strand: Direct

Name: oadA [H]

Synonym: Sbal_1025

Alternate gene names: 126173269

Gene position: 1178251-1180071 (Clockwise)

Preceding gene: 126173268

Following gene: 126173270

Centisome position: 22.98

GC content: 49.97

Gene sequence:

>1821_bases
ATGACTTTTGTATCAAATTCTACGACGGCAGTGGCTAAGCCATTATTTTTAACTGATGTCGTTTTGCGGGACGCGCATCA
ATCCATTTTAGCGACGCGCTTACGCATTGATGACATGTTACCGATAGCGCCATTACTCGATAAGATCGGTTTCTGGTCAC
TGGAATCTTGGGGTGGTGCGACGTTTGATGCCTGTATTCGTTATCTTGGTGAAGATCCTTGGGATCGAATTCGTGAGCTG
AAAAAGGCCATGCCAAATACGCCGCAGCAAATGTTGCTGCGTGGCCAAAACCTCTTAGGTTATCGCCATTATGCCGATGA
TTTAGTGACGCGTTTTGTTGAGCGTGCCCATACCAATGGCGTCGATGTATTTCGTATTTTTGATGCGATGAACGATGTTC
GAAACCTCGAGACTGCGGTGAAAGCAGTGCGCCAAGTTGGCGGCCATGCGCAGGGGACGATTTCGTATACCACGAGTCCA
GTGCATACCATAGAGACGTGGGTTGATATGGCAAAACGTCTCGAAGATATGGGATGCGATTCTTTGTGTATCAAAGATAT
GGCGGGCTTACTTAAGCCGATGGAAGCGTTTGAGCTTATTAGCCGACTCAAATCTCAGACGCAACTCGTGTTATCTATGC
ATTGTCATGCGACGACAGGGTTGAGTACTGCCACTTATCAGAAAGCCATTGAAGCGGGCATCGATGTGCTCGATACGGCA
ATTTCGTCGATGAGTCAAACCTATGGACATACTGCAACTGAAACCGTTATCGCTATGGTGGAAGATACTGAGCGCGCGAC
TGGTTACGATATGGTGTTGCTTGAGGAGATTGCCGCTTATTTCCGTGAAGTGCGCAAGAAGTACGCTAAGTTTGAAGGCG
CACTGAAAGGCATTGATTCGCGTATATTACGTGCACAAGTGCCTGGTGGCATGCTGACAAATATGGAGAGCCAACTAAAG
GAACAAGGTGCGGCCGATAAGATGGACTTGGTATTGGAAGAAATTCCCCGCGTACGTGCTGACTTAGGTTTCTTGCCGTT
AGTGACGCCTACATCGCAGATTGTCGGCTCGCAGGCGGTAATCAATGTGCTAATGGGTGAGCGTTATAAGTCACTGACGA
AAGAGACTGAAGGCGTGCTCAAGGGCGAATATGGCGCGACGCCTGCGCCAGTAGATGCCGCATTGCAAGCCAGAGTGTTG
CAAGGGGCTGAAGCTATTACATGTCGCCCTGCGGATTTATTAACGCCAGAGCTGGCTAAGTTACGGCTCGAGTTGGCAGA
TAAAGCGCAGGAACAAGGCATTCGCCTATCTTCAGAGCATGACGATGATGTGCTGACCTATGCACTCTTCCCACAAATAG
GATTGCAGTTCTTAAAGAATCGTGACGATCCAAGCGCCTTTGAGCCTAAGCCTGAAGTGACTGCGGCACTTGCTACTAAT
GCTGCGGATCGTGGCCAAACCTACACTGTGACTGTCGAAGGGCAAGAGTACGTAGTTGAAGTCGCCGCAGGCGGGGATAT
CTCGCAAATCCAGCCACAGGGCCAAAGTGTTCATGCCGTGCAAACGGCTACGGCGAGCACTATGCCAACTGCGTGCCATG
GAGAGATCAGGCTTGAAATGAGCGCGCCGCTGTCGGGCAACATCTTCAAAGTGCATGTTTCTCCAGGCGATAGAGTGTGT
GAAGGCGATGTCGTGATCATCCTTGAGGCGATGAAGATGGAAACTGAAATTCGTGCTCAGGGCGATGGCATTATCGCTAA
GCTCTGGGTGAAAGAAGGCGACTCAGTGTCTGTGGGTTCTCAATTACTGGCCTTGGCGTAG

Upstream 100 bases:

>100_bases
TAGCGCAATCTCATGCTAAGCCTTTAGACCCAAATGTGGTCGCTGCGATTTCATTGGCGGTAAAGCAGTATCGTTCACAG
ATTAAGTAATGGGGAGCAGT

Downstream 100 bases:

>100_bases
GAGTCATTATGGAAGGTTTAATGGCTTTTTGGGCCGAGACTGGTATTGCCCATTTTACTGGCGGGCAAGTGTTGATGATG
GCTGTGGGCGCTTTGCTCTT

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MTFVSNSTTAVAKPLFLTDVVLRDAHQSILATRLRIDDMLPIAPLLDKIGFWSLESWGGATFDACIRYLGEDPWDRIREL
KKAMPNTPQQMLLRGQNLLGYRHYADDLVTRFVERAHTNGVDVFRIFDAMNDVRNLETAVKAVRQVGGHAQGTISYTTSP
VHTIETWVDMAKRLEDMGCDSLCIKDMAGLLKPMEAFELISRLKSQTQLVLSMHCHATTGLSTATYQKAIEAGIDVLDTA
ISSMSQTYGHTATETVIAMVEDTERATGYDMVLLEEIAAYFREVRKKYAKFEGALKGIDSRILRAQVPGGMLTNMESQLK
EQGAADKMDLVLEEIPRVRADLGFLPLVTPTSQIVGSQAVINVLMGERYKSLTKETEGVLKGEYGATPAPVDAALQARVL
QGAEAITCRPADLLTPELAKLRLELADKAQEQGIRLSSEHDDDVLTYALFPQIGLQFLKNRDDPSAFEPKPEVTAALATN
AADRGQTYTVTVEGQEYVVEVAAGGDISQIQPQGQSVHAVQTATASTMPTACHGEIRLEMSAPLSGNIFKVHVSPGDRVC
EGDVVIILEAMKMETEIRAQGDGIIAKLWVKEGDSVSVGSQLLALA

Sequences:

>Translated_606_residues
MTFVSNSTTAVAKPLFLTDVVLRDAHQSILATRLRIDDMLPIAPLLDKIGFWSLESWGGATFDACIRYLGEDPWDRIREL
KKAMPNTPQQMLLRGQNLLGYRHYADDLVTRFVERAHTNGVDVFRIFDAMNDVRNLETAVKAVRQVGGHAQGTISYTTSP
VHTIETWVDMAKRLEDMGCDSLCIKDMAGLLKPMEAFELISRLKSQTQLVLSMHCHATTGLSTATYQKAIEAGIDVLDTA
ISSMSQTYGHTATETVIAMVEDTERATGYDMVLLEEIAAYFREVRKKYAKFEGALKGIDSRILRAQVPGGMLTNMESQLK
EQGAADKMDLVLEEIPRVRADLGFLPLVTPTSQIVGSQAVINVLMGERYKSLTKETEGVLKGEYGATPAPVDAALQARVL
QGAEAITCRPADLLTPELAKLRLELADKAQEQGIRLSSEHDDDVLTYALFPQIGLQFLKNRDDPSAFEPKPEVTAALATN
AADRGQTYTVTVEGQEYVVEVAAGGDISQIQPQGQSVHAVQTATASTMPTACHGEIRLEMSAPLSGNIFKVHVSPGDRVC
EGDVVIILEAMKMETEIRAQGDGIIAKLWVKEGDSVSVGSQLLALA
>Mature_605_residues
TFVSNSTTAVAKPLFLTDVVLRDAHQSILATRLRIDDMLPIAPLLDKIGFWSLESWGGATFDACIRYLGEDPWDRIRELK
KAMPNTPQQMLLRGQNLLGYRHYADDLVTRFVERAHTNGVDVFRIFDAMNDVRNLETAVKAVRQVGGHAQGTISYTTSPV
HTIETWVDMAKRLEDMGCDSLCIKDMAGLLKPMEAFELISRLKSQTQLVLSMHCHATTGLSTATYQKAIEAGIDVLDTAI
SSMSQTYGHTATETVIAMVEDTERATGYDMVLLEEIAAYFREVRKKYAKFEGALKGIDSRILRAQVPGGMLTNMESQLKE
QGAADKMDLVLEEIPRVRADLGFLPLVTPTSQIVGSQAVINVLMGERYKSLTKETEGVLKGEYGATPAPVDAALQARVLQ
GAEAITCRPADLLTPELAKLRLELADKAQEQGIRLSSEHDDDVLTYALFPQIGLQFLKNRDDPSAFEPKPEVTAALATNA
ADRGQTYTVTVEGQEYVVEVAAGGDISQIQPQGQSVHAVQTATASTMPTACHGEIRLEMSAPLSGNIFKVHVSPGDRVCE
GDVVIILEAMKMETEIRAQGDGIIAKLWVKEGDSVSVGSQLLALA

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=625, Percent_Identity=31.2, Blast_Score=278, Evalue=1e-74,
Organism=Homo sapiens, GI106049295, Length=625, Percent_Identity=31.2, Blast_Score=278, Evalue=1e-74,
Organism=Homo sapiens, GI106049292, Length=625, Percent_Identity=31.2, Blast_Score=278, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17562816, Length=617, Percent_Identity=31.6045380875203, Blast_Score=293, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6319695, Length=635, Percent_Identity=32.2834645669291, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321376, Length=634, Percent_Identity=32.1766561514196, Blast_Score=295, Evalue=1e-80,
Organism=Drosophila melanogaster, GI281363050, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24652224, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24652222, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24652220, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24652218, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24652212, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24652210, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24652214, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI19921944, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24652216, Length=620, Percent_Identity=32.4193548387097, Blast_Score=293, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 66214; Mature: 66082

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFVSNSTTAVAKPLFLTDVVLRDAHQSILATRLRIDDMLPIAPLLDKIGFWSLESWGGA
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
TFDACIRYLGEDPWDRIRELKKAMPNTPQQMLLRGQNLLGYRHYADDLVTRFVERAHTNG
CHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
VDVFRIFDAMNDVRNLETAVKAVRQVGGHAQGTISYTTSPVHTIETWVDMAKRLEDMGCD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC
SLCIKDMAGLLKPMEAFELISRLKSQTQLVLSMHCHATTGLSTATYQKAIEAGIDVLDTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHH
ISSMSQTYGHTATETVIAMVEDTERATGYDMVLLEEIAAYFREVRKKYAKFEGALKGIDS
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILRAQVPGGMLTNMESQLKEQGAADKMDLVLEEIPRVRADLGFLPLVTPTSQIVGSQAV
HHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
INVLMGERYKSLTKETEGVLKGEYGATPAPVDAALQARVLQGAEAITCRPADLLTPELAK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHCCHHHHH
LRLELADKAQEQGIRLSSEHDDDVLTYALFPQIGLQFLKNRDDPSAFEPKPEVTAALATN
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
AADRGQTYTVTVEGQEYVVEVAAGGDISQIQPQGQSVHAVQTATASTMPTACHGEIRLEM
CCCCCCEEEEEECCCEEEEEEECCCCHHHCCCCCCCEEHHHHHHCCCCCCCCCCEEEEEE
SAPLSGNIFKVHVSPGDRVCEGDVVIILEAMKMETEIRAQGDGIIAKLWVKEGDSVSVGS
ECCCCCCEEEEEECCCCCEECCCEEEEEEHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
QLLALA
HHHHCC
>Mature Secondary Structure 
TFVSNSTTAVAKPLFLTDVVLRDAHQSILATRLRIDDMLPIAPLLDKIGFWSLESWGGA
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
TFDACIRYLGEDPWDRIRELKKAMPNTPQQMLLRGQNLLGYRHYADDLVTRFVERAHTNG
CHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
VDVFRIFDAMNDVRNLETAVKAVRQVGGHAQGTISYTTSPVHTIETWVDMAKRLEDMGCD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC
SLCIKDMAGLLKPMEAFELISRLKSQTQLVLSMHCHATTGLSTATYQKAIEAGIDVLDTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHH
ISSMSQTYGHTATETVIAMVEDTERATGYDMVLLEEIAAYFREVRKKYAKFEGALKGIDS
HHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILRAQVPGGMLTNMESQLKEQGAADKMDLVLEEIPRVRADLGFLPLVTPTSQIVGSQAV
HHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
INVLMGERYKSLTKETEGVLKGEYGATPAPVDAALQARVLQGAEAITCRPADLLTPELAK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCHHHCCHHHHH
LRLELADKAQEQGIRLSSEHDDDVLTYALFPQIGLQFLKNRDDPSAFEPKPEVTAALATN
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
AADRGQTYTVTVEGQEYVVEVAAGGDISQIQPQGQSVHAVQTATASTMPTACHGEIRLEM
CCCCCCEEEEEECCCEEEEEEECCCCHHHCCCCCCCEEHHHHHHCCCCCCCCCCEEEEEE
SAPLSGNIFKVHVSPGDRVCEGDVVIILEAMKMETEIRAQGDGIIAKLWVKEGDSVSVGS
ECCCCCCEEEEEECCCCCEECCCEEEEEEHHHHHHHHHHCCCCEEEEEEECCCCCCCHHH
QLLALA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]