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The map label for this gene is hlyB [H]

Identifier: 126173115

GI number: 126173115

Start: 982214

End: 983878

Strand: Direct

Name: hlyB [H]

Synonym: Sbal_0870

Alternate gene names: 126173115

Gene position: 982214-983878 (Clockwise)

Preceding gene: 126173114

Following gene: 126173117

Centisome position: 19.16

GC content: 46.61

Gene sequence:

>1665_bases
ATGTCTAAGTTGAGTTTACGCAATAAATTACTATTGCTATCGCTGTTCCCTTTGATCTTCGCATTACTCATATTGATGTC
GGTTTCCTATTATGTCGAACAAGATGCACTTGCCGCTGAAGTGGTCACTTTTAAAACTAAGCTCGTCGGTGAGCGCAAAC
AACAAATCAAAGAAGCCACCGAAATTGCCGCTGGGATTATTAATTATCAATTGTCGTTAAAAGAACAAGGCAATGTGAAT
CAAGCACTCAGAGACATACGTTTCGGTAGCGCGGGTTACTTCTTTATTTATGATTCCCAAGGTAAAAATATCTTTCATGC
CCTAATCCCGAGTTTAGAAGGGCAAAACAAGATGGATATGACAGATCCCCGCGGCACTAAAATTATCGTCGGCCTGCTCG
ACGCCGCTAAACGTGGCGATGGTAATTTCTCCTACTACTACCAAAAACCCAATACTAATGAGCAGATTGAGAAGATCAGC
TACGCCATGATGATCCCAGGCACAGACTGGATGTTAGGTACTGGGGCCTATATTGATGATATCGATGCCGTTGTTGAGGA
ATATCGCGCCACAGTGACAGAACAAATGGCAGATAAATCCTTCGCCATTTTACTGATAGCACTGTTCCTTACGGGTATTA
CTGGCTTTATCATCATGATCGCTGCCCACCGTATGGTCGTGCCAATCAAGAATATGGCTGATAACTTGAATGATATCGCT
AAGGGCGAAGGGGATTTAACCAAACGACTCGCCGTAAAAGGGGAGGACGAAATCGCTCAACTTGGACGTTCCTTTAACCT
CTTTGTCGATAAGCTGCAAAATATCATCGGCGATGTGGCGACGGCGACCGCTAAAGTGAAAACAGCGGCTAATGCGATTC
ATGCGCAAACTAAAGTTATGTCGAGTCAGTTAGTCAGTCATAACAATGAAACCGATCAGGTGGTGACGGCGATTACTGAG
ATGTCATCCACCGCTAACGAAGTGGCAAAAAATACCACTCAAGTGGCTGAGGCGACCCACGCAGCAACGGGCGATGTGGC
TAATGCCCAGCGCTGTGTTGATGCTTCGCTTGAAGAAATTGCCTCTTTAATGTCGCAAATCAATAATGCGGCGGGCAGTA
TCAAATCACTCAGCGAGCAATCCCAGAAAATCAACAGCGTACTGTCAGTGATTGGTGGTATTGCCGAGCAGACCAACCTA
TTGGCATTAAACGCCGCCATCGAAGCGGCCCGTGCCGGTGAACAGGGCCGAGGTTTTGCTGTGGTCGCCGATGAGGTGCG
TAACTTAGCCAGCCGCACTCAAGCGAGTACGTTAGAAATCAATGAGATGTTATCGGCATTACATAAGCTAGTGACCCAAG
CCGTGAAAGCGATGGAAGAGAGTCAACAAAGCTGCGTGCGTTCGGTGGATTCTTCTCGCACGATTTCCGACAGTCTGGGT
TCAGTGACTTCGGCTGTGACTGCGATTAACGATATGAGTACCCAAATCGCGGCCGCGGCGACAGAGCAAAGCTCAGTAAC
TGAAGAAATTAACCGCAATGTGTATGCCATCCAAGAGATTGTAAATGAGCTACTGCACTCCAGTGAAGATGCGGCCAGAG
TGAGTCTGACGGTATCAGAGGAAGGTATTAACTTAGGTAAATTAGTGGGACAGTTTAGGATTTAA

Upstream 100 bases:

>100_bases
TTGAGCAAGATTAAGATTTTGTTACTTTAAGCGCATAGAGAAATAACAATGTTAGCTATACTCCAAAGATACAAGTTGTA
TTCCTTTGGAGCATTCAAGC

Downstream 100 bases:

>100_bases
TTACATCAATCTAAATAAAAAAATGGGAGACTTAAGGTCTCCCGTTTTTATTTGGCTCGTTTATTTTTTAAGCGTTAATT
CAGCTGAGTGAATTCATCCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSKLSLRNKLLLLSLFPLIFALLILMSVSYYVEQDALAAEVVTFKTKLVGERKQQIKEATEIAAGIINYQLSLKEQGNVN
QALRDIRFGSAGYFFIYDSQGKNIFHALIPSLEGQNKMDMTDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKIS
YAMMIPGTDWMLGTGAYIDDIDAVVEEYRATVTEQMADKSFAILLIALFLTGITGFIIMIAAHRMVVPIKNMADNLNDIA
KGEGDLTKRLAVKGEDEIAQLGRSFNLFVDKLQNIIGDVATATAKVKTAANAIHAQTKVMSSQLVSHNNETDQVVTAITE
MSSTANEVAKNTTQVAEATHAATGDVANAQRCVDASLEEIASLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNL
LALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLSALHKLVTQAVKAMEESQQSCVRSVDSSRTISDSLG
SVTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAARVSLTVSEEGINLGKLVGQFRI

Sequences:

>Translated_554_residues
MSKLSLRNKLLLLSLFPLIFALLILMSVSYYVEQDALAAEVVTFKTKLVGERKQQIKEATEIAAGIINYQLSLKEQGNVN
QALRDIRFGSAGYFFIYDSQGKNIFHALIPSLEGQNKMDMTDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKIS
YAMMIPGTDWMLGTGAYIDDIDAVVEEYRATVTEQMADKSFAILLIALFLTGITGFIIMIAAHRMVVPIKNMADNLNDIA
KGEGDLTKRLAVKGEDEIAQLGRSFNLFVDKLQNIIGDVATATAKVKTAANAIHAQTKVMSSQLVSHNNETDQVVTAITE
MSSTANEVAKNTTQVAEATHAATGDVANAQRCVDASLEEIASLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNL
LALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLSALHKLVTQAVKAMEESQQSCVRSVDSSRTISDSLG
SVTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAARVSLTVSEEGINLGKLVGQFRI
>Mature_553_residues
SKLSLRNKLLLLSLFPLIFALLILMSVSYYVEQDALAAEVVTFKTKLVGERKQQIKEATEIAAGIINYQLSLKEQGNVNQ
ALRDIRFGSAGYFFIYDSQGKNIFHALIPSLEGQNKMDMTDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKISY
AMMIPGTDWMLGTGAYIDDIDAVVEEYRATVTEQMADKSFAILLIALFLTGITGFIIMIAAHRMVVPIKNMADNLNDIAK
GEGDLTKRLAVKGEDEIAQLGRSFNLFVDKLQNIIGDVATATAKVKTAANAIHAQTKVMSSQLVSHNNETDQVVTAITEM
SSTANEVAKNTTQVAEATHAATGDVANAQRCVDASLEEIASLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNLL
ALNAAIEAARAGEQGRGFAVVADEVRNLASRTQASTLEINEMLSALHKLVTQAVKAMEESQQSCVRSVDSSRTISDSLGS
VTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAARVSLTVSEEGINLGKLVGQFRI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=290, Percent_Identity=33.1034482758621, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787690, Length=391, Percent_Identity=27.1099744245524, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788195, Length=297, Percent_Identity=29.96632996633, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788194, Length=337, Percent_Identity=29.673590504451, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1789453, Length=337, Percent_Identity=27.5964391691395, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59817; Mature: 59686

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLSLRNKLLLLSLFPLIFALLILMSVSYYVEQDALAAEVVTFKTKLVGERKQQIKEAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAAGIINYQLSLKEQGNVNQALRDIRFGSAGYFFIYDSQGKNIFHALIPSLEGQNKMDM
HHHHHHHHHEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCC
TDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKISYAMMIPGTDWMLGTGAYIDD
CCCCCCEEEEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHHEEEECCCCCEEECCCHHHH
IDAVVEEYRATVTEQMADKSFAILLIALFLTGITGFIIMIAAHRMVVPIKNMADNLNDIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHCHHHHH
KGEGDLTKRLAVKGEDEIAQLGRSFNLFVDKLQNIIGDVATATAKVKTAANAIHAQTKVM
CCCCHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSQLVSHNNETDQVVTAITEMSSTANEVAKNTTQVAEATHAATGDVANAQRCVDASLEEI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ASLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEE
VVADEVRNLASRTQASTLEINEMLSALHKLVTQAVKAMEESQQSCVRSVDSSRTISDSLG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SVTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAARVSLTVSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEEEC
EGINLGKLVGQFRI
CCCCHHHHHHHCCC
>Mature Secondary Structure 
SKLSLRNKLLLLSLFPLIFALLILMSVSYYVEQDALAAEVVTFKTKLVGERKQQIKEAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIAAGIINYQLSLKEQGNVNQALRDIRFGSAGYFFIYDSQGKNIFHALIPSLEGQNKMDM
HHHHHHHHHEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCC
TDPRGTKIIVGLLDAAKRGDGNFSYYYQKPNTNEQIEKISYAMMIPGTDWMLGTGAYIDD
CCCCCCEEEEEEHHHHCCCCCCEEEEEECCCCHHHHHHHHHEEEECCCCCEEECCCHHHH
IDAVVEEYRATVTEQMADKSFAILLIALFLTGITGFIIMIAAHRMVVPIKNMADNLNDIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHCHHHHH
KGEGDLTKRLAVKGEDEIAQLGRSFNLFVDKLQNIIGDVATATAKVKTAANAIHAQTKVM
CCCCHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSQLVSHNNETDQVVTAITEMSSTANEVAKNTTQVAEATHAATGDVANAQRCVDASLEEI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ASLMSQINNAAGSIKSLSEQSQKINSVLSVIGGIAEQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEE
VVADEVRNLASRTQASTLEINEMLSALHKLVTQAVKAMEESQQSCVRSVDSSRTISDSLG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SVTSAVTAINDMSTQIAAAATEQSSVTEEINRNVYAIQEIVNELLHSSEDAARVSLTVSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEEEC
EGINLGKLVGQFRI
CCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]