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The map label for this gene is rtn [H]

Identifier: 126172953

GI number: 126172953

Start: 799168

End: 800688

Strand: Direct

Name: rtn [H]

Synonym: Sbal_0705

Alternate gene names: 126172953

Gene position: 799168-800688 (Clockwise)

Preceding gene: 126172952

Following gene: 126172958

Centisome position: 15.59

GC content: 42.87

Gene sequence:

>1521_bases
ATGCGAAGAAAAATAGCAAAATTGAATCTGCCATTGTGGCAATGGCTGGCAGTGATATTGTTTCCCATTGGGGTTGCTGT
TGTAGCAAGTTATCTCTCTGCACAGTATTTTGTGGAAGATAAAGTCAAAGGTGTGGGGGGGATTTATGTAGGCAACATAG
ATACTTTGATCTCTCATGCCGATGAAATCAGCCATTATGCATTGGCGTTGAAGGACACTGAGTGTCAAGAATTACACAAC
TATATGTTGTTCCAGCCTTACTTTCGCTCGGCTTTAATATTTGATTCGCAACGTGTTTATTGTTCATCTAAAACAGGTGA
TATCGACGTTCCTTTAGGCATAGTCAGTACCACTGAAAATCTTGAAATACCTAACCAGTTTATTATTGGCGGCACGCCTT
TTATGCCTGAGGTGCCTGCGATAGTGGCATCAAACTGGGAACCGATATCTAAGCACGGCGCTGCTGTGATTATTGAAGGG
CAATATTTATTAGACTCCTTTGTACAACCCAATGTGTTTCCCAGCGCAGTGATCAATGTCGCTTTATCTATAAATGGTAA
AACGATTCCAGAGTCACCCGAATTTAAACAAAATGAGGTGATGACGCTCGATTCTGATAAGCACAATTTTTCAGTGTTAT
TAGCAATGTCACCTGCCTTTTTCTGGCATTTCTTTTGGATATTTTTGGCCATTTCTTTGCCCGTTAGCATAGTCTTGATT
ACGGGGACTATCCTATTTGTGCTCTATTCAAGGGTTACTCGCCATTCCCTTGCCGATGACATTCGCAGTGGGATAGAGAA
CGAAGAGTTTTTCTTGGTTTATCAGCCAGTGATTTGTGCCGAGGACGGTAAGGCAAAAGGCGTTGAGGCATTAGTGCGTT
GGCAGCACCCACAAATGGGCTTAGTGCGGCCTGATTTGTTTATTCCCATTGCCGAAGAGGGCAAGTTAATTGTCCCATTA
ACCAACTATATTTTTGAGCGGGCATTAAAAGATTTTGCCGATATGAAGGTCGAACCGGGCTTTAGAATTGCGTTTAACGT
GGCGCCAGAACACTTTACGCAGGATGATATTGAGTCGAAATTTATTCATCTGCGGGATTCCCTGGAGCGTATTGGCGTTA
AGCCTTTGATTGAAATCACCGAACGGCAATTATTAACGCCGGATATTTGCCAGTGTATTGAAAGCTTGCGACAGTTAGGG
ATTCTAGTGGCAATTGATGACTTTGGTACCGGGCAAACCACTTTATCCCTGCTGCAAACGATGCCGTTAGACTATCTGAA
AATTGATAAATGCTTTATCGATACCATAGGACAAGATTCTGTCACTTCCCATGTGCTCGATACTATTATCGAGCTTTCCC
ACAAGATGAATTATGTCGTGGTGGCAGAGGGGGTTGAGACGCAGGAGCAGGCGGATTATTTAACCAGTCGCCAAGTGCAT
TTTCTACAAGGGTATCTCTTTGCTAAGCCGATGAAACTCGCCGATTTAAAGCTATGGTTAGTTGAGCATTTTAAACATTA
G

Upstream 100 bases:

>100_bases
GATATGAACTGAGATACAAACATATACATACCTTGCCGCTTAGATTTTGATACCATTTTTAACCGAGTGCTGTGCGAGTT
AAGGAACTAAACAGAGAACT

Downstream 100 bases:

>100_bases
CATCATCAAACCAGTCAGCAATAAGGGCATCTAGGTGCCCTTATTGCTGTTCAAGCGTTATAGCTAAAAGTGCGTGTTAA
AGGCTTTGGTTTAAGCCTCT

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGGIYVGNIDTLISHADEISHYALALKDTECQELHN
YMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSTTENLEIPNQFIIGGTPFMPEVPAIVASNWEPISKHGAAVIIEG
QYLLDSFVQPNVFPSAVINVALSINGKTIPESPEFKQNEVMTLDSDKHNFSVLLAMSPAFFWHFFWIFLAISLPVSIVLI
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMGLVRPDLFIPIAEEGKLIVPL
TNYIFERALKDFADMKVEPGFRIAFNVAPEHFTQDDIESKFIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLG
ILVAIDDFGTGQTTLSLLQTMPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYVVVAEGVETQEQADYLTSRQVH
FLQGYLFAKPMKLADLKLWLVEHFKH

Sequences:

>Translated_506_residues
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGGIYVGNIDTLISHADEISHYALALKDTECQELHN
YMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSTTENLEIPNQFIIGGTPFMPEVPAIVASNWEPISKHGAAVIIEG
QYLLDSFVQPNVFPSAVINVALSINGKTIPESPEFKQNEVMTLDSDKHNFSVLLAMSPAFFWHFFWIFLAISLPVSIVLI
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMGLVRPDLFIPIAEEGKLIVPL
TNYIFERALKDFADMKVEPGFRIAFNVAPEHFTQDDIESKFIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLG
ILVAIDDFGTGQTTLSLLQTMPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYVVVAEGVETQEQADYLTSRQVH
FLQGYLFAKPMKLADLKLWLVEHFKH
>Mature_506_residues
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGGIYVGNIDTLISHADEISHYALALKDTECQELHN
YMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSTTENLEIPNQFIIGGTPFMPEVPAIVASNWEPISKHGAAVIIEG
QYLLDSFVQPNVFPSAVINVALSINGKTIPESPEFKQNEVMTLDSDKHNFSVLLAMSPAFFWHFFWIFLAISLPVSIVLI
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMGLVRPDLFIPIAEEGKLIVPL
TNYIFERALKDFADMKVEPGFRIAFNVAPEHFTQDDIESKFIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLG
ILVAIDDFGTGQTTLSLLQTMPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYVVVAEGVETQEQADYLTSRQVH
FLQGYLFAKPMKLADLKLWLVEHFKH

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=464, Percent_Identity=32.5431034482759, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI87081845, Length=515, Percent_Identity=29.126213592233, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87081980, Length=434, Percent_Identity=33.6405529953917, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1786507, Length=315, Percent_Identity=35.5555555555556, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87081743, Length=309, Percent_Identity=33.0097087378641, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1790496, Length=304, Percent_Identity=31.25, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787541, Length=256, Percent_Identity=33.203125, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI87081921, Length=256, Percent_Identity=32.8125, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=29.5081967213115, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI226510982, Length=252, Percent_Identity=32.5396825396825, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI87082096, Length=245, Percent_Identity=29.7959183673469, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787055, Length=244, Percent_Identity=30.7377049180328, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 57138; Mature: 57138

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGGIYVGNIDTLISHA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHH
DEISHYALALKDTECQELHNYMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSTTEN
HHHHHEEEEECCCHHHHHHHHHEECHHHHHEEEECCCEEEEECCCCCEECCEEEEECCCC
LEIPNQFIIGGTPFMPEVPAIVASNWEPISKHGAAVIIEGQYLLDSFVQPNVFPSAVINV
CCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCEEEEECHHHHHHHCCCCCCHHHHEEE
ALSINGKTIPESPEFKQNEVMTLDSDKHNFSVLLAMSPAFFWHFFWIFLAISLPVSIVLI
EEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECEEEECCCCCCCHHHHHHCCCCCCC
LVRPDLFIPIAEEGKLIVPLTNYIFERALKDFADMKVEPGFRIAFNVAPEHFTQDDIESK
CCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHH
FIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLGILVAIDDFGTGQTTLSLLQT
HHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
MPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYVVVAEGVETQEQADYLTSRQVH
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCHHH
FLQGYLFAKPMKLADLKLWLVEHFKH
HHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRKIAKLNLPLWQWLAVILFPIGVAVVASYLSAQYFVEDKVKGVGGIYVGNIDTLISHA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHH
DEISHYALALKDTECQELHNYMLFQPYFRSALIFDSQRVYCSSKTGDIDVPLGIVSTTEN
HHHHHEEEEECCCHHHHHHHHHEECHHHHHEEEECCCEEEEECCCCCEECCEEEEECCCC
LEIPNQFIIGGTPFMPEVPAIVASNWEPISKHGAAVIIEGQYLLDSFVQPNVFPSAVINV
CCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCEEEEECHHHHHHHCCCCCCHHHHEEE
ALSINGKTIPESPEFKQNEVMTLDSDKHNFSVLLAMSPAFFWHFFWIFLAISLPVSIVLI
EEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHH
TGTILFVLYSRVTRHSLADDIRSGIENEEFFLVYQPVICAEDGKAKGVEALVRWQHPQMG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECEEEECCCCCCCHHHHHHCCCCCCC
LVRPDLFIPIAEEGKLIVPLTNYIFERALKDFADMKVEPGFRIAFNVAPEHFTQDDIESK
CCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHH
FIHLRDSLERIGVKPLIEITERQLLTPDICQCIESLRQLGILVAIDDFGTGQTTLSLLQT
HHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
MPLDYLKIDKCFIDTIGQDSVTSHVLDTIIELSHKMNYVVVAEGVETQEQADYLTSRQVH
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCHHH
FLQGYLFAKPMKLADLKLWLVEHFKH
HHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]