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The map label for this gene is yisQ [H]

Identifier: 126172898

GI number: 126172898

Start: 736905

End: 738266

Strand: Direct

Name: yisQ [H]

Synonym: Sbal_0649

Alternate gene names: 126172898

Gene position: 736905-738266 (Clockwise)

Preceding gene: 126172896

Following gene: 126172900

Centisome position: 14.37

GC content: 51.76

Gene sequence:

>1362_bases
GTGGCTAAAGCACCCAAAACATTGCAACAACGCATGAGCATAGTCGCCCTCACTTGGCCGATTTTTGTCGAGACCTTGCT
GCAATCACTGCTTGGGATCAGCGACATTTTTATGCTCAGCCACTATTCCGATAATGCGGTTGCCGCGGTGGGACTCACGA
CTCAGCTGATGTTCTTCATGATGGTTATGTCCATGATGGTGAGCACAGGTGCGAGCATTTTGATTAGCCAGAACAATGGC
GCAGGCCAGTCGCAACAGGCTGTCGATATCGGGGTGGCAAGTGTCGCATTGAGCTTAGGGCTCGCCTTGATCATGGGCGC
CTCTATGTTCTTCGGCGCCAAGGGGATTATCGGCCTGTTTGCACTGGAACACGATGTGGCAGGCTTTGGATATGACTACT
TAGTGATTTGCGGCAGCTTGAGTATAGGCTTGGTCATGAACATCGCTTTTGCCGCGATTCTAAGGAGTTACGGCTTTACC
CGCTCGGCCATGTTAGTCACTTCAAGCACAGGCTTGATGAACGTCATCGGTAACTATATTGCCCTGTATTCTCCCTTTGA
CTTGCCTGTTTATGGGGTAACAGGGGTGGCAATTTCCACCGTCACCAGCCAGATCATCGGCGCTGTGATCATGCTAATGG
TGATCCGCTTTAAAAAGATCCCGCTGCCACTGCAACGGCTTAAATTATTACCGCGCAGCACCTATTGGAGCGTGATGCGT
ATCGGCCTACTCAATGCCGGTGAGATGTTGTCTTACAATGTGGCGCAGATGACCATCATCTATTTTATCAGTCAAATGGG
GACTTTATCGCTCACGGCTTATACCTATGGCCTAAACATCAGCCGGTTTATCTATTGTTTTGCGGTGGCGCTCGGTCAGG
CGACGCAAATTCAGACCGGGTACTATGTTGGCAAACAATGGTTCGATGAAATCACTGCGAGAGTGCAACGTTACTGTCTG
GTGGGCTTTGTCGCTTCGCTGGCCATAGTCTTAGTCTTCTACTGGCAGCGATTCACTATTGTTGGCTGGTTAAGTGAGAA
CGAGGAAGTCATCCAACTGACGGCGTTATTACTGGCAGGTTCTATCGCGCTTGAAACAGGGCGGGTGTTTAATCTGGTGA
TTATTTCGGCGCTCAAGGGCGCGGGTGATGTGGCGTTCCCAGTGCGGGTTGGCCTCTTTAGCATGTGGGGCATAGGGGTA
TTATTGGCTTGGTTCTTTGGCCTTCACTTAGGCTATGGCGTACTCGCCGCTTGGCTTGCCGTCGCCGCCGATGAGTGGAT
CCGCGGCCTGATTATGGTGTACCGCTGGCGCTCGTGCCGTTGGCAACGTTTTACTCGCATACCCGCTGCGACTGCAGTGT
AG

Upstream 100 bases:

>100_bases
CAGTATCTTGGCTAAAATATAGGTTGCCAAGATGCCGTTTGAGCAACACATTGAGCCAGCGCTCACATCGTTATCCGTAC
TCTATTTGTAGGAATTCTCC

Downstream 100 bases:

>100_bases
TTTTGGTGAGGTGAATTGGAAGCGCAGCAAACATTGGCTGCGCTTTTTGTTTGATAAGCTTAACTTTGCTGCTTCAACAG
GGTACGGCACAGCTTGATAA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MAKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFMMVMSMMVSTGASILISQNNG
AGQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLFALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFT
RSAMLVTSSTGLMNVIGNYIALYSPFDLPVYGVTGVAISTVTSQIIGAVIMLMVIRFKKIPLPLQRLKLLPRSTYWSVMR
IGLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTGYYVGKQWFDEITARVQRYCL
VGFVASLAIVLVFYWQRFTIVGWLSENEEVIQLTALLLAGSIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGV
LLAWFFGLHLGYGVLAAWLAVAADEWIRGLIMVYRWRSCRWQRFTRIPAATAV

Sequences:

>Translated_453_residues
MAKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFMMVMSMMVSTGASILISQNNG
AGQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLFALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFT
RSAMLVTSSTGLMNVIGNYIALYSPFDLPVYGVTGVAISTVTSQIIGAVIMLMVIRFKKIPLPLQRLKLLPRSTYWSVMR
IGLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTGYYVGKQWFDEITARVQRYCL
VGFVASLAIVLVFYWQRFTIVGWLSENEEVIQLTALLLAGSIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGV
LLAWFFGLHLGYGVLAAWLAVAADEWIRGLIMVYRWRSCRWQRFTRIPAATAV
>Mature_452_residues
AKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFMMVMSMMVSTGASILISQNNGA
GQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLFALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFTR
SAMLVTSSTGLMNVIGNYIALYSPFDLPVYGVTGVAISTVTSQIIGAVIMLMVIRFKKIPLPLQRLKLLPRSTYWSVMRI
GLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTGYYVGKQWFDEITARVQRYCLV
GFVASLAIVLVFYWQRFTIVGWLSENEEVIQLTALLLAGSIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGVL
LAWFFGLHLGYGVLAAWLAVAADEWIRGLIMVYRWRSCRWQRFTRIPAATAV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=445, Percent_Identity=23.3707865168539, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49536; Mature: 49404

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEHHHHHHHHHHH
MVMSMMVSTGASILISQNNGAGQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLF
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFTRSAMLVTSSTGLMNVIGNYI
HHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
ALYSPFDLPVYGVTGVAISTVTSQIIGAVIMLMVIRFKKIPLPLQRLKLLPRSTYWSVMR
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHH
IGLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTG
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEECC
YYVGKQWFDEITARVQRYCLVGFVASLAIVLVFYWQRFTIVGWLSENEEVIQLTALLLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHH
SIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGVLLAWFFGLHLGYGVLAAWLA
HHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAADEWIRGLIMVYRWRSCRWQRFTRIPAATAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKAPKTLQQRMSIVALTWPIFVETLLQSLLGISDIFMLSHYSDNAVAAVGLTTQLMFFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEHHHHHHHHHHH
MVMSMMVSTGASILISQNNGAGQSQQAVDIGVASVALSLGLALIMGASMFFGAKGIIGLF
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ALEHDVAGFGYDYLVICGSLSIGLVMNIAFAAILRSYGFTRSAMLVTSSTGLMNVIGNYI
HHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
ALYSPFDLPVYGVTGVAISTVTSQIIGAVIMLMVIRFKKIPLPLQRLKLLPRSTYWSVMR
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHH
IGLLNAGEMLSYNVAQMTIIYFISQMGTLSLTAYTYGLNISRFIYCFAVALGQATQIQTG
HHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEECC
YYVGKQWFDEITARVQRYCLVGFVASLAIVLVFYWQRFTIVGWLSENEEVIQLTALLLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHH
SIALETGRVFNLVIISALKGAGDVAFPVRVGLFSMWGIGVLLAWFFGLHLGYGVLAAWLA
HHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAADEWIRGLIMVYRWRSCRWQRFTRIPAATAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]