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The map label for this gene is ywrD [H]

Identifier: 126172853

GI number: 126172853

Start: 689113

End: 690825

Strand: Direct

Name: ywrD [H]

Synonym: Sbal_0604

Alternate gene names: 126172853

Gene position: 689113-690825 (Clockwise)

Preceding gene: 126172852

Following gene: 126172854

Centisome position: 13.44

GC content: 49.04

Gene sequence:

>1713_bases
ATGATAAAAACAATAAAATCAATTTGTACCTTAGTGACAGTGGCGACGGCAATATCGTCTTCAGGAGTGATGGCCATGGA
TAGGATCACGGGTAAAGCCTTTGCGACGCGCTCAGAAGTGTATGCCACCCATGGAATGGCGGCGACCAGTCAACCACTCG
CCACGCAAGTCGCTATTGATATACTCAAGCAGGGCGGCAGCGCGGTCGATGCGGCGATTGCCGCCAATGCCATGCTAGGG
TTAGTCGAACCAACGGGTTCGGGTGTTGGTGGTGACTTGTTTGCCATCGTCTGGAGCGCGAAAGATCAACGTCTCTATGG
CCTTAACGCTTCGGGTCGCAGTCCAAAATCCTTAAGTTTAGAAAAGCTTAAATCCCTCGGCTTAGACTATTTGCCACCGC
TTGGGCCTTTGCCTGTTTCTGTGCCCGGCGCTGTGGATGGTTGGTATGAACTGCATAATAAGTTCGGCAAATTAGCTATG
GCCGCTAATCTCGCGCCCGCAATCCACTATGCCCGTGATGGTTTTCCTGTCTCCGAATTGATTGCTTATTATCTTGAGGG
TAGCGGTAAAAAACTCGCAAAATTCCCCGGTTTTAAAGAAACTTATATGCCTAATGGCAAGATGCCAGCGGTGGGCGAAA
TCTTTAAAAACCCAGCGCTTGCTAATACCTATGAGAAAATTGCCAAGGGTGGCCGCGATGCTTTCTATAAAGGCGATATC
GCCAAAAGTATCGATAAGTACATGAAATCCCAAGGTGGTTATTTAAGTTATGATGACTTAGCCAGCCATACTAGCGACTG
GATAGAGCCGGTTTCGGTGAACTACCGTGGTTACGATGTATGGGAACTGCCGCCCAATGGTCAAGGTATTGCGGCGCTGC
AAATCCTAAAAACCATGGAACCCTTTAATGTGGCTGCTATGGGCTTTAATAGCCCCGAATATGTGCATTTATTTGTCGAA
GCCAAAAAACTCGCCTTTGCCGACAGAGCTAAGTTTTATGCCGACATGGCCTTTAATAAAGTGCCGGTTAACGAGTTGAT
TTCGCAGCAATACAATTATGATCGCGCTAAGTTAATCGATCCCAATAAAGCGGCCAAGAGTGTTGATGCGGGTAATCCAG
CATTGCAACATGGCGATACTGTGTACCTGACCACCGCCGACAAAGATGGCAACATGGTGTCACTCATTCAAAGTAACTAC
CGTGGTATGGGTTCAGGGATGACACCGCCGGATCTCGGCTTTGTGCTGCAAGACCGTGGGCAAATGTTTGATTTAACGGA
AGGGCGTTTTAATACCTACGCACCTGGCAAGCGTCCATTTCATACTATCATTCCCGCTTTTGTGACCAAAGACGGCAAAC
CTTGGCTCAGCTTTGGGGTGATGGGCGGCGCGACTCAACCACAAATGCACGCGCAGATTGTAATGAACCTGATTGATTTT
AAAATGAACTTGCAAGAAGCGGGCGATGCCCCCAGAATTTTGCATATGGGTTCAACTGAGCCCACCGGCGAAGTGATGAA
TGACGGCGGCTACGTCAGTCTGGAATCGGGCTTCCCTGTGGAAACGCGCCGTGAGCTTATCAAGAAAGGTCATGTGCTGC
GTGACGGCCTTGGCGATTTTGGCGGCTATCAAGCTATTGGATTTAATGCTGAAACGGGCGTGTATCGTGCGGCTTCTGAG
AGCCGTAAAGATGGTCATGCCGCCGGTTATTAA

Upstream 100 bases:

>100_bases
ACGACATTTTTGCTTACGTTTAACTTGGGCCAATGCGGTATTGGTTGGTGATATTTTCGACCATCCTTGTTACCTTAATT
TCTCCAGAGTGGGAGGAATT

Downstream 100 bases:

>100_bases
CTTCAGCGTCACGCTAAGGTAAGCTTGAGGCAGAGTAAGCTTTGCTTCATTTATCCGATTAAACTGATTGACGAGACTTT
TACAGTCTCGTCAATTTTTA

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAIDILKQGGSAVDAAIAANAMLG
LVEPTGSGVGGDLFAIVWSAKDQRLYGLNASGRSPKSLSLEKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAM
AANLAPAIHYARDGFPVSELIAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
AKSIDKYMKSQGGYLSYDDLASHTSDWIEPVSVNYRGYDVWELPPNGQGIAALQILKTMEPFNVAAMGFNSPEYVHLFVE
AKKLAFADRAKFYADMAFNKVPVNELISQQYNYDRAKLIDPNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNY
RGMGSGMTPPDLGFVLQDRGQMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQIVMNLIDF
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDFGGYQAIGFNAETGVYRAASE
SRKDGHAAGY

Sequences:

>Translated_570_residues
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAIDILKQGGSAVDAAIAANAMLG
LVEPTGSGVGGDLFAIVWSAKDQRLYGLNASGRSPKSLSLEKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAM
AANLAPAIHYARDGFPVSELIAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
AKSIDKYMKSQGGYLSYDDLASHTSDWIEPVSVNYRGYDVWELPPNGQGIAALQILKTMEPFNVAAMGFNSPEYVHLFVE
AKKLAFADRAKFYADMAFNKVPVNELISQQYNYDRAKLIDPNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNY
RGMGSGMTPPDLGFVLQDRGQMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQIVMNLIDF
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDFGGYQAIGFNAETGVYRAASE
SRKDGHAAGY
>Mature_570_residues
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAIDILKQGGSAVDAAIAANAMLG
LVEPTGSGVGGDLFAIVWSAKDQRLYGLNASGRSPKSLSLEKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAM
AANLAPAIHYARDGFPVSELIAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
AKSIDKYMKSQGGYLSYDDLASHTSDWIEPVSVNYRGYDVWELPPNGQGIAALQILKTMEPFNVAAMGFNSPEYVHLFVE
AKKLAFADRAKFYADMAFNKVPVNELISQQYNYDRAKLIDPNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNY
RGMGSGMTPPDLGFVLQDRGQMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQIVMNLIDF
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDFGGYQAIGFNAETGVYRAASE
SRKDGHAAGY

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=562, Percent_Identity=27.9359430604982, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI73915090, Length=562, Percent_Identity=27.9359430604982, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI73915096, Length=562, Percent_Identity=27.9359430604982, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI73915094, Length=562, Percent_Identity=27.9359430604982, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI113429324, Length=556, Percent_Identity=25.8992805755396, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI113429326, Length=561, Percent_Identity=25.8467023172906, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI153266885, Length=557, Percent_Identity=24.4165170556553, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI153266901, Length=558, Percent_Identity=24.3727598566308, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI109148539, Length=469, Percent_Identity=26.226012793177, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI153266907, Length=557, Percent_Identity=23.5188509874327, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1789856, Length=565, Percent_Identity=31.5044247787611, Blast_Score=233, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI193208245, Length=520, Percent_Identity=27.3076923076923, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI193208247, Length=520, Percent_Identity=27.3076923076923, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17542894, Length=498, Percent_Identity=25.9036144578313, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI212646519, Length=559, Percent_Identity=25.4025044722719, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI72000294, Length=559, Percent_Identity=25.4025044722719, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17506189, Length=529, Percent_Identity=24.5746691871456, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI161077880, Length=551, Percent_Identity=27.9491833030853, Blast_Score=162, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24642670, Length=551, Percent_Identity=27.9491833030853, Blast_Score=162, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24642666, Length=551, Percent_Identity=27.9491833030853, Blast_Score=162, Evalue=7e-40,
Organism=Drosophila melanogaster, GI161077878, Length=551, Percent_Identity=27.9491833030853, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI45551474, Length=551, Percent_Identity=27.9491833030853, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI18859893, Length=461, Percent_Identity=26.0303687635575, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI161077496, Length=555, Percent_Identity=24.8648648648649, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI18859741, Length=469, Percent_Identity=23.6673773987207, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 61476; Mature: 61476

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAID
CCHHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ILKQGGSAVDAAIAANAMLGLVEPTGSGVGGDLFAIVWSAKDQRLYGLNASGRSPKSLSL
HHHCCCCHHHHHHHHHHHEEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCH
EKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAMAANLAPAIHYARDGFPVSEL
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
HHHHHCCCCCHHHHCCCCCHHCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCEECCHH
AKSIDKYMKSQGGYLSYDDLASHTSDWIEPVSVNYRGYDVWELPPNGQGIAALQILKTME
HHHHHHHHHCCCCEECHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHHHCC
PFNVAAMGFNSPEYVHLFVEAKKLAFADRAKFYADMAFNKVPVNELISQQYNYDRAKLID
CCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEC
PNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNYRGMGSGMTPPDLGFVLQDRG
CCHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEHEEHHCCCCCCCCCCCCCCCCEECCCC
QMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQIVMNLIDF
CEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDF
HHCHHHCCCCCEEEECCCCCCCCHHCCCCCEEEECCCCCHHHHHHHHHCCCHHHHCCCCC
GGYQAIGFNAETGVYRAASESRKDGHAAGY
CCCEEEECCCCCCCEECCHHCCCCCCCCCC
>Mature Secondary Structure
MIKTIKSICTLVTVATAISSSGVMAMDRITGKAFATRSEVYATHGMAATSQPLATQVAID
CCHHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ILKQGGSAVDAAIAANAMLGLVEPTGSGVGGDLFAIVWSAKDQRLYGLNASGRSPKSLSL
HHHCCCCHHHHHHHHHHHEEEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCH
EKLKSLGLDYLPPLGPLPVSVPGAVDGWYELHNKFGKLAMAANLAPAIHYARDGFPVSEL
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IAYYLEGSGKKLAKFPGFKETYMPNGKMPAVGEIFKNPALANTYEKIAKGGRDAFYKGDI
HHHHHCCCCCHHHHCCCCCHHCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCEECCHH
AKSIDKYMKSQGGYLSYDDLASHTSDWIEPVSVNYRGYDVWELPPNGQGIAALQILKTME
HHHHHHHHHCCCCEECHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHHHCC
PFNVAAMGFNSPEYVHLFVEAKKLAFADRAKFYADMAFNKVPVNELISQQYNYDRAKLID
CCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEC
PNKAAKSVDAGNPALQHGDTVYLTTADKDGNMVSLIQSNYRGMGSGMTPPDLGFVLQDRG
CCHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEHEEHHCCCCCCCCCCCCCCCCEECCCC
QMFDLTEGRFNTYAPGKRPFHTIIPAFVTKDGKPWLSFGVMGGATQPQMHAQIVMNLIDF
CEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
KMNLQEAGDAPRILHMGSTEPTGEVMNDGGYVSLESGFPVETRRELIKKGHVLRDGLGDF
HHCHHHCCCCCEEEECCCCCCCCHHCCCCCEEEECCCCCHHHHHHHHHCCCHHHHCCCCC
GGYQAIGFNAETGVYRAASESRKDGHAAGY
CCCEEEECCCCCCCEECCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]