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The map label for this gene is pabA [H]

Identifier: 126172816

GI number: 126172816

Start: 639750

End: 640334

Strand: Direct

Name: pabA [H]

Synonym: Sbal_0567

Alternate gene names: 126172816

Gene position: 639750-640334 (Clockwise)

Preceding gene: 126172815

Following gene: 126172817

Centisome position: 12.48

GC content: 49.4

Gene sequence:

>585_bases
ATGTTGCTAATGATTGATAATTACGACTCTTTTACCTTTAACTTAGTGCAGTATTTTCAGCAGCTAGGGCAAGAGATAGT
GGTCAAACGTAATGACGAAATTAGCATCGCCGAAATCGAGGCACTTGCGCCTACTCATCTAGTGATTTCGCCCGGCCCTT
GCACTCCCAATGAGGCGGGGGTTTCCCTTGCGGCGATTAAACATTTTGCCACGCGCATGCCGATCCTAGGTGTGTGTTTA
GGGCATCAGGCGATGGCGCAGGTTTTTGGTGCCAATGTGGTGCGTGCCGAGCGGGTAATGCACGGCAAGGTCAGCGCCAT
TGCGCATACTGGCCAGCGGTTATTTGAGGGATTAAATCAGCCCTTAACCGTCACACGTTATCACTCGTTATTGGTGGATG
CTGTGCCTGAAGGTTTTGTTCTCGATGCTTGGTTTGATGATCCGATCCATGGCCGAGAAATCATGGCCATGAGTCATCAG
GACTTACCGCTGTATGGGGTGCAATTTCATCCCGAATCGATTCTCACCGAGCAAGGTCTCGAACTATTAGCCAATTTTTT
AGCGCAATCGGCTGTGCCTGTATAA

Upstream 100 bases:

>100_bases
TAATTGGCTAAACCTTGAGGATAAGGTGTGGTAGCATTTGCGCCCGCATTCATCCGTCGGATATGCGTTACCTTTACCCA
TTTAGGCCAATGGATCTTGT

Downstream 100 bases:

>100_bases
TTTCCTCGCCCTAAAAACTCCCCCCACTATATTCGTACTATCAATTTCTGTTACAAGATTTATCCTTTTTTTAAGCAAGT
TTAGCAATTAACTATGCTAT

Product: glutamine amidotransferase of anthranilate synthase

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISIAEIEALAPTHLVISPGPCTPNEAGVSLAAIKHFATRMPILGVCL
GHQAMAQVFGANVVRAERVMHGKVSAIAHTGQRLFEGLNQPLTVTRYHSLLVDAVPEGFVLDAWFDDPIHGREIMAMSHQ
DLPLYGVQFHPESILTEQGLELLANFLAQSAVPV

Sequences:

>Translated_194_residues
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISIAEIEALAPTHLVISPGPCTPNEAGVSLAAIKHFATRMPILGVCL
GHQAMAQVFGANVVRAERVMHGKVSAIAHTGQRLFEGLNQPLTVTRYHSLLVDAVPEGFVLDAWFDDPIHGREIMAMSHQ
DLPLYGVQFHPESILTEQGLELLANFLAQSAVPV
>Mature_194_residues
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISIAEIEALAPTHLVISPGPCTPNEAGVSLAAIKHFATRMPILGVCL
GHQAMAQVFGANVVRAERVMHGKVSAIAHTGQRLFEGLNQPLTVTRYHSLLVDAVPEGFVLDAWFDDPIHGREIMAMSHQ
DLPLYGVQFHPESILTEQGLELLANFLAQSAVPV

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=119, Percent_Identity=35.2941176470588, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=62.4338624338624, Blast_Score=248, Evalue=2e-67,
Organism=Escherichia coli, GI1787517, Length=190, Percent_Identity=42.1052631578947, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1788854, Length=194, Percent_Identity=26.2886597938144, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI133901714, Length=141, Percent_Identity=31.9148936170213, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71992710, Length=141, Percent_Identity=31.9148936170213, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71992717, Length=141, Percent_Identity=31.9148936170213, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=193, Percent_Identity=41.9689119170984, Blast_Score=159, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6324361, Length=213, Percent_Identity=31.924882629108, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323873, Length=153, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281365319, Length=143, Percent_Identity=30.0699300699301, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 21357; Mature: 21357

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISIAEIEALAPTHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCCEEHHHCCCEEEEEECCCCCCCCCC
VSLAAIKHFATRMPILGVCLGHQAMAQVFGANVVRAERVMHGKVSAIAHTGQRLFEGLNQ
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLTVTRYHSLLVDAVPEGFVLDAWFDDPIHGREIMAMSHQDLPLYGVQFHPESILTEQGL
CEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHH
ELLANFLAQSAVPV
HHHHHHHHHHCCCC
>Mature Secondary Structure
MLLMIDNYDSFTFNLVQYFQQLGQEIVVKRNDEISIAEIEALAPTHLVISPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCCEEHHHCCCEEEEEECCCCCCCCCC
VSLAAIKHFATRMPILGVCLGHQAMAQVFGANVVRAERVMHGKVSAIAHTGQRLFEGLNQ
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLTVTRYHSLLVDAVPEGFVLDAWFDDPIHGREIMAMSHQDLPLYGVQFHPESILTEQGL
CEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHH
ELLANFLAQSAVPV
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673 [H]