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The map label for this gene is hflC [H]

Identifier: 126172810

GI number: 126172810

Start: 634631

End: 635524

Strand: Direct

Name: hflC [H]

Synonym: Sbal_0561

Alternate gene names: 126172810

Gene position: 634631-635524 (Clockwise)

Preceding gene: 126172809

Following gene: 126172811

Centisome position: 12.38

GC content: 43.4

Gene sequence:

>894_bases
ATGGGTAGATTAAGCGTTATTCTTATCGCCGTACTCTTAGGTATTGGTTTGTCATCTTTAATGGTGGTGAATGAAGGCGA
GCGCGCAATTGTGGCGCGTTTCGGGGAAATTTTAAAAGACAACGTTGACGGTAATCGAGTCACCCGCGTCTACGGTCCAG
GTCTGCACATTAAAGTGCCTGTGATCGATAAAGTAAAATTACTCGATGCCCGTATTCAAACACTCGATGGTGCTGCAGAT
CGTTTTGTGACTTCAGAGAAGAAAGACCTTATGGTCGATTCCTATGTGAAGTGGCGTATTGCAGATTTCGAAAAATATTA
CCTGTCTACAAACGGTGGTATTAAGTCGAATGCAGAATCGCTATTACAACGTAAGATCAACAACGATTTACGTACTGAGT
TTGGTCGTCGCACTATCAGAGAGATTGTCTCTGGTAAGCGTGATGAATTGCAAAATGACGCGTTAGAAAACGCCTCAGAA
AGCGCCAAAGACTTAGGTATTGAAGTTGTCGATGTGCGTGTAAAGCAAATCAATTTACCTGCTAACGTCAGTAACAGTAT
TTACCAACGTATGCGTGCCGAGCGTCAAGCTGTGGCAAAAGAGCATAGAGCACAAGGTAAAGAGCAATCTGAAATCATTC
GTGCAACGATTGATGCCAATGTAACAGTGAAGATTGCTGAAGCTGAGCGTAAAGCTTTAACCATACGTGGTGAAGGTGAT
GCATTAGCTGCGAAGATATATTCTGATGCTTACAGCAAAGATGCTGAGTTCTTCGGCTTTGTTCGTAGCTTAGAAGCCTA
TCGTGCCAGCTTCTCAGGCAAGTCCGATATCATGGTGTTAGAGCCTGATAGCGAGTTCTTCAAGTATATGAAGAGCACTG
CACCTAAGAAGTAA

Upstream 100 bases:

>100_bases
AAATGTCAATTCTTCATCTGTATCAACGACTCGCGCGAATGAGCCTTTGAGTGGACGTCCATCCCGCGATGATCGTACTC
GCCAAGGGAGGGAGTAATCC

Downstream 100 bases:

>100_bases
TACGTTAAAAGTATTGATCTAATAGGCCCTGTTACCCAGGGCCTATTTTTTTATCTGGCGATTGTTAACTTAGATTAAAA
AGTCAGGGCTAATTTATATT

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MGRLSVILIAVLLGIGLSSLMVVNEGERAIVARFGEILKDNVDGNRVTRVYGPGLHIKVPVIDKVKLLDARIQTLDGAAD
RFVTSEKKDLMVDSYVKWRIADFEKYYLSTNGGIKSNAESLLQRKINNDLRTEFGRRTIREIVSGKRDELQNDALENASE
SAKDLGIEVVDVRVKQINLPANVSNSIYQRMRAERQAVAKEHRAQGKEQSEIIRATIDANVTVKIAEAERKALTIRGEGD
ALAAKIYSDAYSKDAEFFGFVRSLEAYRASFSGKSDIMVLEPDSEFFKYMKSTAPKK

Sequences:

>Translated_297_residues
MGRLSVILIAVLLGIGLSSLMVVNEGERAIVARFGEILKDNVDGNRVTRVYGPGLHIKVPVIDKVKLLDARIQTLDGAAD
RFVTSEKKDLMVDSYVKWRIADFEKYYLSTNGGIKSNAESLLQRKINNDLRTEFGRRTIREIVSGKRDELQNDALENASE
SAKDLGIEVVDVRVKQINLPANVSNSIYQRMRAERQAVAKEHRAQGKEQSEIIRATIDANVTVKIAEAERKALTIRGEGD
ALAAKIYSDAYSKDAEFFGFVRSLEAYRASFSGKSDIMVLEPDSEFFKYMKSTAPKK
>Mature_296_residues
GRLSVILIAVLLGIGLSSLMVVNEGERAIVARFGEILKDNVDGNRVTRVYGPGLHIKVPVIDKVKLLDARIQTLDGAADR
FVTSEKKDLMVDSYVKWRIADFEKYYLSTNGGIKSNAESLLQRKINNDLRTEFGRRTIREIVSGKRDELQNDALENASES
AKDLGIEVVDVRVKQINLPANVSNSIYQRMRAERQAVAKEHRAQGKEQSEIIRATIDANVTVKIAEAERKALTIRGEGDA
LAAKIYSDAYSKDAEFFGFVRSLEAYRASFSGKSDIMVLEPDSEFFKYMKSTAPKK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=313, Percent_Identity=52.0766773162939, Blast_Score=316, Evalue=1e-87,
Organism=Escherichia coli, GI1786697, Length=293, Percent_Identity=24.5733788395904, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193209764, Length=205, Percent_Identity=24.8780487804878, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 33165; Mature: 33034

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLSVILIAVLLGIGLSSLMVVNEGERAIVARFGEILKDNVDGNRVTRVYGPGLHIKVP
CCHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEC
VIDKVKLLDARIQTLDGAADRFVTSEKKDLMVDSYVKWRIADFEKYYLSTNGGIKSNAES
CHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHEEEECCEEEEEECCCCCCCCHHH
LLQRKINNDLRTEFGRRTIREIVSGKRDELQNDALENASESAKDLGIEVVDVRVKQINLP
HHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCC
ANVSNSIYQRMRAERQAVAKEHRAQGKEQSEIIRATIDANVTVKIAEAERKALTIRGEGD
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHEECCCEEEEEEECCCEEEEEECCCC
ALAAKIYSDAYSKDAEFFGFVRSLEAYRASFSGKSDIMVLEPDSEFFKYMKSTAPKK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
GRLSVILIAVLLGIGLSSLMVVNEGERAIVARFGEILKDNVDGNRVTRVYGPGLHIKVP
CHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEC
VIDKVKLLDARIQTLDGAADRFVTSEKKDLMVDSYVKWRIADFEKYYLSTNGGIKSNAES
CHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHEEEECCEEEEEECCCCCCCCHHH
LLQRKINNDLRTEFGRRTIREIVSGKRDELQNDALENASESAKDLGIEVVDVRVKQINLP
HHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCC
ANVSNSIYQRMRAERQAVAKEHRAQGKEQSEIIRATIDANVTVKIAEAERKALTIRGEGD
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEHEECCCEEEEEEECCCEEEEEECCCC
ALAAKIYSDAYSKDAEFFGFVRSLEAYRASFSGKSDIMVLEPDSEFFKYMKSTAPKK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]