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The map label for this gene is caiD [C]

Identifier: 126172782

GI number: 126172782

Start: 595776

End: 596582

Strand: Direct

Name: caiD [C]

Synonym: Sbal_0533

Alternate gene names: 126172782

Gene position: 595776-596582 (Clockwise)

Preceding gene: 126172779

Following gene: 126172785

Centisome position: 11.62

GC content: 50.81

Gene sequence:

>807_bases
ATGAGTGGCCAAAGTGTACAAGTCAAAATCGATGATGGCATCGCCTATGTGTTGCTTAATCGTCCTGAAAAAATGAATGC
GATTAATTATTTAATGTTTAGTGAGCTCGACCGTGCAATTAAACAGATCAAATCCAATCGTGGGGTGCGAGCGGTGATCG
TCTCGGGTGCGGGGGGCAATTTTAGCTCAGGGCTCGATGTCAAAAGCGTGATGTCGGCACCCATGCAGGCGGTAAAATTA
CTGTTTAAGGGCTTACCGGGGAATGCGAACTTAGCACAGCGGGTGTCATTAGGTTGGCAAAACTTGCCCGTACCTGTGAT
TGCCGTACTTGAAGGCTGTTGCTATGGCGGCGGTATGCAAATCGCCTTGGGCGCAGATGTGCGCATCGCCAGCCATGACT
GTAAGCTATCTATAATGGAAGCAAAATGGGGACTCGTGCCCGATATGGCTGGATTGGTCGCGTTAAGGCAAATCATGCCT
AAGGATCAAGCCATGCTGCTGAGCCTGACGGCAAAAGTGCTTGAGGGCAATGAAGCGCTGACCTTAGGACTCGTGACGCA
AGTGAGCGAGACGCCGATGGAAGTGGCTCAACAATTGGCGCAGCAACTGATGCAAACCTCACCTGATGCAGCAGCGGCCA
TCAAACTCAGCATTAACCGCAGTTGGACTGCTTCGGTGCGGAGTCTGCTTTGCCGTGAGTCGATTAGTCAGATTCGGTTA
TTGTTAGGCAAAAATTGCAAGATAGCGGCGGCGCGTCAGCTGAAAGAGCCGCAGAAACCTTATCAAGATCGTCAGTCGGG
TTGGTAA

Upstream 100 bases:

>100_bases
TTTTGACTCAAGTCAAAAAACAGGCTCATGTTATATCTTTTAGTGAATTATTCCAAACGTGTTAACATTTATTCTGGACT
GACCAGTAACGGAATATTTC

Downstream 100 bases:

>100_bases
TGCTATTTTGTCTGAATTAGCTTGAATCGCCGTATTTATTGAGCGCCGCTCATGCGGGCAGAAAAGCCTTTAATCGCATT
TAAGCAATTCTGCCATGCGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSGQSVQVKIDDGIAYVLLNRPEKMNAINYLMFSELDRAIKQIKSNRGVRAVIVSGAGGNFSSGLDVKSVMSAPMQAVKL
LFKGLPGNANLAQRVSLGWQNLPVPVIAVLEGCCYGGGMQIALGADVRIASHDCKLSIMEAKWGLVPDMAGLVALRQIMP
KDQAMLLSLTAKVLEGNEALTLGLVTQVSETPMEVAQQLAQQLMQTSPDAAAAIKLSINRSWTASVRSLLCRESISQIRL
LLGKNCKIAAARQLKEPQKPYQDRQSGW

Sequences:

>Translated_268_residues
MSGQSVQVKIDDGIAYVLLNRPEKMNAINYLMFSELDRAIKQIKSNRGVRAVIVSGAGGNFSSGLDVKSVMSAPMQAVKL
LFKGLPGNANLAQRVSLGWQNLPVPVIAVLEGCCYGGGMQIALGADVRIASHDCKLSIMEAKWGLVPDMAGLVALRQIMP
KDQAMLLSLTAKVLEGNEALTLGLVTQVSETPMEVAQQLAQQLMQTSPDAAAAIKLSINRSWTASVRSLLCRESISQIRL
LLGKNCKIAAARQLKEPQKPYQDRQSGW
>Mature_267_residues
SGQSVQVKIDDGIAYVLLNRPEKMNAINYLMFSELDRAIKQIKSNRGVRAVIVSGAGGNFSSGLDVKSVMSAPMQAVKLL
FKGLPGNANLAQRVSLGWQNLPVPVIAVLEGCCYGGGMQIALGADVRIASHDCKLSIMEAKWGLVPDMAGLVALRQIMPK
DQAMLLSLTAKVLEGNEALTLGLVTQVSETPMEVAQQLAQQLMQTSPDAAAAIKLSINRSWTASVRSLLCRESISQIRLL
LGKNCKIAAARQLKEPQKPYQDRQSGW

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI157694516, Length=242, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI213417737, Length=242, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI70995211, Length=235, Percent_Identity=29.7872340425532, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI194097323, Length=217, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI68989263, Length=197, Percent_Identity=27.4111675126904, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI31542718, Length=198, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI260274832, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI45643119, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI260275230, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157694520, Length=220, Percent_Identity=26.3636363636364, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4502327, Length=217, Percent_Identity=29.4930875576037, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI20127408, Length=182, Percent_Identity=28.021978021978, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI221142681, Length=215, Percent_Identity=33.0232558139535, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787660, Length=232, Percent_Identity=30.6034482758621, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788682, Length=208, Percent_Identity=31.25, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790281, Length=179, Percent_Identity=26.2569832402235, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787659, Length=217, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788597, Length=219, Percent_Identity=25.1141552511416, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082183, Length=220, Percent_Identity=23.6363636363636, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=244, Percent_Identity=31.1475409836066, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17536985, Length=234, Percent_Identity=25.6410256410256, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17534483, Length=267, Percent_Identity=27.7153558052434, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17558304, Length=211, Percent_Identity=27.0142180094787, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=209, Percent_Identity=24.8803827751196, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=217, Percent_Identity=25.3456221198157, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=222, Percent_Identity=23.4234234234234, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=197, Percent_Identity=27.9187817258883, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=212, Percent_Identity=25.9433962264151, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=28.6274509803922, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28571730, Length=177, Percent_Identity=28.2485875706215, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571729, Length=177, Percent_Identity=28.2485875706215, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19920382, Length=256, Percent_Identity=24.21875, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129971, Length=176, Percent_Identity=26.7045454545455, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653477, Length=176, Percent_Identity=26.7045454545455, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357171, Length=188, Percent_Identity=24.468085106383, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19922422, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28902; Mature: 28771

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQSVQVKIDDGIAYVLLNRPEKMNAINYLMFSELDRAIKQIKSNRGVRAVIVSGAGGN
CCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
FSSGLDVKSVMSAPMQAVKLLFKGLPGNANLAQRVSLGWQNLPVPVIAVLEGCCYGGGMQ
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCEE
IALGADVRIASHDCKLSIMEAKWGLVPDMAGLVALRQIMPKDQAMLLSLTAKVLEGNEAL
EEECCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
TLGLVTQVSETPMEVAQQLAQQLMQTSPDAAAAIKLSINRSWTASVRSLLCRESISQIRL
EEHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LLGKNCKIAAARQLKEPQKPYQDRQSGW
HHCCCCCHHHHHHHCCCCCCHHHHCCCC
>Mature Secondary Structure 
SGQSVQVKIDDGIAYVLLNRPEKMNAINYLMFSELDRAIKQIKSNRGVRAVIVSGAGGN
CCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
FSSGLDVKSVMSAPMQAVKLLFKGLPGNANLAQRVSLGWQNLPVPVIAVLEGCCYGGGMQ
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCEE
IALGADVRIASHDCKLSIMEAKWGLVPDMAGLVALRQIMPKDQAMLLSLTAKVLEGNEAL
EEECCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEE
TLGLVTQVSETPMEVAQQLAQQLMQTSPDAAAAIKLSINRSWTASVRSLLCRESISQIRL
EEHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LLGKNCKIAAARQLKEPQKPYQDRQSGW
HHCCCCCHHHHHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA