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The map label for this gene is hgdC [H]

Identifier: 125625270

GI number: 125625270

Start: 2469872

End: 2474182

Strand: Reverse

Name: hgdC [H]

Synonym: llmg_2516

Alternate gene names: 125625270

Gene position: 2474182-2469872 (Counterclockwise)

Preceding gene: 125625272

Following gene: 125625269

Centisome position: 97.81

GC content: 39.18

Gene sequence:

>4311_bases
TTGACACAAATTTATAAAACAGGGATTGACGTTGGTTCAACCACAGTAAAACTCGTCGTTTTTGACGAAAATTATAAACT
CATTTTTTCACGTTACGAGCGCCACTTTTCTGACGTTAAAGCAGCAACCATTAAAGTATTCAATGATTTTATTGCCGAAC
ACGGAGATTTAAACTTAGAATTAGCCATTACCGGTTCAGGAGGAATGGGACTTGCAGAAGTCATTGACGTTCCCTTTGTC
CAAGAAGTGATTGCCTCATCAATTACCATCGAAAAATTCATTCCACAAACAGATGTCATGATTGAGCTTGGTGGCGAAGA
TGCCAAGATGACATTTTTTGACAATGGCACCCAAGAATTACGGATGAACGGAACTTGTGCCGGTGGGACAGGTGCTTTCA
TTGACCAAATGGCTGCCCTTTTGAAAGTTGATGCTAATGGTGTCAATGAATTAGCTAAAAACTATGAGAAACTCTATCCA
ATCGCTTCACGTTGTGGTGTTTTTGCCAAAACTGACGTTCAACCCCTTTTGAACGAAGGAGTGCGTCGTGAAGATATAGC
AGCCAGTATTTTCCAAGCTGTTGTCAATCAAACCATTGCTGGTTTAGCCAGTGGTCGAAGAATCAAAGGCAATGTCGCCT
TTCTTGGCGGTCCACTCTTCTTTATGAGTGAATTGCGCAAACGTTTCATTGAAACATTAGACTTAAAAGAAGAAAATATT
ATCTTCCCAGAAAATCCACAACTTTTTGTGGCAATGGGAGCAGCGCTTTATGAAGAAACAAGCCAAAAAACGGCAACCGA
ACTCATTCATAGTTTGGAAAATGATGATTCTGATAGTTTGATTCCCCAAGACACCATGGATAAGCTCTTTGAAAATCAAG
CTGAACTTGATGAATTTCGTGCGCGCCATGCCAAAGCAACGGCCAATTATAAAGAACTCAATGAGCATCACGGCGCGGCC
TTTTTAGGAATTGACGCAGGCTCAACCACAACAAAAGTCGTTCTTATTGATGGTGAAGGAAATATTCTTTATGACCACTA
TGGTTCTAATAACGGTGAACCACTTGAATCAGTTATTAATATTTTAAAAGATGTTTATGCTAAACTTCCAGCAGATGTTT
ACATTGCCAAATCAACCGTAACCGGTTACGGCGAACACTTGATTAAAGCTGGTCTTCACGTGGATTACGGCGAAGTCGAA
ACCATGGCTCACTACAAAGCCGCTGATTACTTCAATCCAGGTGTTGATTTCATTCTCGATATCGGCGGCCAAGACATGAA
AGCCATGCGAATCCGTGATGGTGCTTTATCTAGTATTCAGCTCAATGAAGCTTGTTCATCAGGTTGTGGCTCATTTATTG
AAACTTTCGCCCATTCGCTCAGACATGACGTTCGTGAATTTTCACAAAAAGCGCTTTTAGCTGAGCATCCAGTAAATCTT
GGATCACGCTGTACAGTCTTTATGAACTCAAAAGTCAAGCAAGTTCAAAAAGAAGGAGCGACAGTTGGCGATATTTCCGC
TGGACTTTCCTACAGTGTCATCAAAAATGCCCTCTATAAAGTTATCAAGGTAAAACGTCCCGAAGAACTTGGTAAGAAAA
TCGTTGTTCAAGGGGGAACTTTCTACAACGAAGCCGTTTTGCGTGCCTTTGAAAAAATTTCTGAACGTGAAGTTGTCCGT
CCAAGTATCGCTGGACTAATGGGAGCTTATGGTTGTGCTTTGATTTCTTTAGACAATGAAGAAACACACAAAGAATCAGA
GCTTTTAAAACTTGATGAATTAGAAAAATTTACCACTCATAAAGAATTTATGGTCTGTGGACTTTGCGAAAATAATTGCA
AAATGACGCTGACGGTCTTCAATGATGGCAATAAGTTTGTAACCGGGAACCGTTGTGAACGTGGTGCTGAAAAAGCAACA
AAAGTCAAAGTTGCTAAAAAAGACAAAAAAGTTAATTTAGTTGATTATAAATACAAAAAACTTTTCCGTTACCATAGTTT
AAGTAAGAAAAAACAAACTCGTGGAGAGATTGGGATTCCGCGCGTGCTTAACATGTACGAAAATTATCCGCTTTGGCACA
CGATGCTAACAGACCTTGGCTTCCGTGTTGTTTTGAGCCCACGCTCAGACAAAGAACTCTTTGAAGAGGGAATTGAAACT
ATTCCGTCTGATACTGTTTGTTACCCAGCAAAAATGAGTCACGGACATATCATGGCTTTGATTAAACAAGGTGTGCCAAC
TATCTTTTATCCTTCAGTCCTTTTTGAACAAGAAGAACAAAAAAATGCTCAAAATCATTTCAACTGTCCAATTGTCCAAT
CTTATCCAGAAGTTCTTAAAAATAATATTGACGAAATTCGTGAAGGACAAGTCAATTATCTTCATCCATTTATTAATTTG
GCAAATCCTGACGGTGTGGCAGTCAATATCCATAAGTCTTTGACGGCTCAAGGATTTACTGTCAGTCTTGAAGAAGTAGA
AGCTGCCGTTCAACATGGTTTTGAAGAAATGGATAAATTCAAAGAAGACTTACGTCTTAAAGCCGAAGATTTACTGATGC
AAATTAATTTGAACAATGAAAAAGCCATTGTTCTTGCAGGACGTCCTTATCATTTGGATCCAGAAATCAATCACGGAATT
GCTGACATCATTACTCAAGAAGGATTCCATGTGCTGACAGAAGACTCTATCAGTCATTTGGCCGAAGTTTCTGGTCTGCG
CGTGGTCAATCAATGGGTTTACCACAGTCGTCTTTATGCAGCCGCAAATGTTGTTTGCAAAAATAAAAATCTAGAACTTG
TGCAACTTAATTCCTTTGGTTGTGGTCTTGATGCCGTAACGACAGACCAAGTTGAAGAAATCATGCGTGGACACAACAAG
CTTTATACCGTTCTAAAAATTGATGAAGGTTCAAATATGGGAGCCGTTCGGATTCGCTTGCGTAGCCTTAAGGCAGCAGT
ATCAGAGCGGACACGTCACAACATTGAAGTGACAACCGAAGTTCATGAGTTAGTCCCAGAAACACCAGCATTCACAAAAG
AAATGGCTAAAAAACATACCCTTCTTTTACCAATGTTGTCACCAATTCACCAAGAAGGACTATTGGATACAGCTTTTGCT
GCTGCAGGTTATAATGTCGTTTCTCTGCCAGAAACAAATACTTCTGTAAATAACGGCTTGAAATTTGTTAATAATGACTC
ATGTTATCCAGCCATCATCACTATCGGTCAACTTATCGAAGCTCTCCAGTCAGGAGAATATGACCTTGACAATACCTCCG
TCATGATGACCCAAACCGGTGGAGGTTGTCGTGCAACCAATTATATTCCTTTGTTGCGTAAAGCTCTGATTGATGCAGGT
TTCCCGCAAGTTCCAGTAGTTTCTCTCTCAATGGGAAATCAAGGGACAGAAAAAGGCTTTAAATTCACGGTTCCATTACT
GACACGCTTTATGATTGCTGTGCTTTACGGCGATTTGTTTGAACGTGTTGTCTATCGGACACGCCCCTATGAAGCAGTAG
AAGGTTCGGTCAATGATTTACATGCAAAATGGCTAGAAAAAGCTCGAAAAAATGTAGAATCAGGGTCAATCTTTGAATTT
AATCGCAACATGAAAAAAATCGTTGCAGAATTTGACCAAATTGAACTTCTTGATATTCAAAAGCCACGAGTGGGTGTCGT
CGGCGAAATCTTAGTCAAATATAGTAAAACTGCTAATAATGATATTGTTTCCATTATTGAAGAAGAGGGCGGCGAAGCTG
TTGTTCTTGATTTAATTGGTTTTATGAATTACAGTTTATACAATCAAATCTGGAAAGCAGATGAGATTGCCTTTAGTAAG
AAAAATAAACTCATGGCTAAAACCTTTATTGGAATCATCAATATGCTAGAAAAACCAATGAATAAAGCTTTGAAGGCATC
AAATCGTTTTGATTCAATAGAGTCAATTTATGACGTTGCATCCTCTACTGAAGAAGTGATTTCAATAGGAAATCACACTG
GTGAGGGCTGGTTCCTTACTGGAGAAATGATTGAACTTTTGCAAAAAGGAGTGAATAATATTATTTGTCTTCAACCTTTT
GGTTGTCTCCCAAATCACATTGTTGGTAAAGGAATGATGAAAGAACTTCGTCGTCAGTATCCAGGGGCTAATCTTGCGCC
GATTGATTATGACCCAGGAGTTTCTGCTGTCAATCAATTGAATCGAATTCGTTTAATGATGACCACTGCTAAAAAAAGAA
TGAACAAAGTTTCTGATTCAGTTGAAAAATCAGAAACAGAGTCCAAATTAGAAACTGCTCAAGCATATTAA

Upstream 100 bases:

>100_bases
AAAGATAAATTAGATAAAAAATCTAATTTGCCGAAAAATGAATATTAAGGATTTAGAGGACTTGTTCAAGTGATATTTCT
CACATAACTAGGAGACCATC

Downstream 100 bases:

>100_bases
AAAGAAAATATAAAAGATACTGACAGCTTTGTCAGTATCTTTCTTTTTCCGAATAGTAACAAATGTTATCAATGCTCGTT
ATCAATTCTTGGTATCAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: 2-hydroxyglutaryl-CoA dehydratase component A [H]

Number of amino acids: Translated: 1436; Mature: 1435

Protein sequence:

>1436_residues
MTQIYKTGIDVGSTTVKLVVFDENYKLIFSRYERHFSDVKAATIKVFNDFIAEHGDLNLELAITGSGGMGLAEVIDVPFV
QEVIASSITIEKFIPQTDVMIELGGEDAKMTFFDNGTQELRMNGTCAGGTGAFIDQMAALLKVDANGVNELAKNYEKLYP
IASRCGVFAKTDVQPLLNEGVRREDIAASIFQAVVNQTIAGLASGRRIKGNVAFLGGPLFFMSELRKRFIETLDLKEENI
IFPENPQLFVAMGAALYEETSQKTATELIHSLENDDSDSLIPQDTMDKLFENQAELDEFRARHAKATANYKELNEHHGAA
FLGIDAGSTTTKVVLIDGEGNILYDHYGSNNGEPLESVINILKDVYAKLPADVYIAKSTVTGYGEHLIKAGLHVDYGEVE
TMAHYKAADYFNPGVDFILDIGGQDMKAMRIRDGALSSIQLNEACSSGCGSFIETFAHSLRHDVREFSQKALLAEHPVNL
GSRCTVFMNSKVKQVQKEGATVGDISAGLSYSVIKNALYKVIKVKRPEELGKKIVVQGGTFYNEAVLRAFEKISEREVVR
PSIAGLMGAYGCALISLDNEETHKESELLKLDELEKFTTHKEFMVCGLCENNCKMTLTVFNDGNKFVTGNRCERGAEKAT
KVKVAKKDKKVNLVDYKYKKLFRYHSLSKKKQTRGEIGIPRVLNMYENYPLWHTMLTDLGFRVVLSPRSDKELFEEGIET
IPSDTVCYPAKMSHGHIMALIKQGVPTIFYPSVLFEQEEQKNAQNHFNCPIVQSYPEVLKNNIDEIREGQVNYLHPFINL
ANPDGVAVNIHKSLTAQGFTVSLEEVEAAVQHGFEEMDKFKEDLRLKAEDLLMQINLNNEKAIVLAGRPYHLDPEINHGI
ADIITQEGFHVLTEDSISHLAEVSGLRVVNQWVYHSRLYAAANVVCKNKNLELVQLNSFGCGLDAVTTDQVEEIMRGHNK
LYTVLKIDEGSNMGAVRIRLRSLKAAVSERTRHNIEVTTEVHELVPETPAFTKEMAKKHTLLLPMLSPIHQEGLLDTAFA
AAGYNVVSLPETNTSVNNGLKFVNNDSCYPAIITIGQLIEALQSGEYDLDNTSVMMTQTGGGCRATNYIPLLRKALIDAG
FPQVPVVSLSMGNQGTEKGFKFTVPLLTRFMIAVLYGDLFERVVYRTRPYEAVEGSVNDLHAKWLEKARKNVESGSIFEF
NRNMKKIVAEFDQIELLDIQKPRVGVVGEILVKYSKTANNDIVSIIEEEGGEAVVLDLIGFMNYSLYNQIWKADEIAFSK
KNKLMAKTFIGIINMLEKPMNKALKASNRFDSIESIYDVASSTEEVISIGNHTGEGWFLTGEMIELLQKGVNNIICLQPF
GCLPNHIVGKGMMKELRRQYPGANLAPIDYDPGVSAVNQLNRIRLMMTTAKKRMNKVSDSVEKSETESKLETAQAY

Sequences:

>Translated_1436_residues
MTQIYKTGIDVGSTTVKLVVFDENYKLIFSRYERHFSDVKAATIKVFNDFIAEHGDLNLELAITGSGGMGLAEVIDVPFV
QEVIASSITIEKFIPQTDVMIELGGEDAKMTFFDNGTQELRMNGTCAGGTGAFIDQMAALLKVDANGVNELAKNYEKLYP
IASRCGVFAKTDVQPLLNEGVRREDIAASIFQAVVNQTIAGLASGRRIKGNVAFLGGPLFFMSELRKRFIETLDLKEENI
IFPENPQLFVAMGAALYEETSQKTATELIHSLENDDSDSLIPQDTMDKLFENQAELDEFRARHAKATANYKELNEHHGAA
FLGIDAGSTTTKVVLIDGEGNILYDHYGSNNGEPLESVINILKDVYAKLPADVYIAKSTVTGYGEHLIKAGLHVDYGEVE
TMAHYKAADYFNPGVDFILDIGGQDMKAMRIRDGALSSIQLNEACSSGCGSFIETFAHSLRHDVREFSQKALLAEHPVNL
GSRCTVFMNSKVKQVQKEGATVGDISAGLSYSVIKNALYKVIKVKRPEELGKKIVVQGGTFYNEAVLRAFEKISEREVVR
PSIAGLMGAYGCALISLDNEETHKESELLKLDELEKFTTHKEFMVCGLCENNCKMTLTVFNDGNKFVTGNRCERGAEKAT
KVKVAKKDKKVNLVDYKYKKLFRYHSLSKKKQTRGEIGIPRVLNMYENYPLWHTMLTDLGFRVVLSPRSDKELFEEGIET
IPSDTVCYPAKMSHGHIMALIKQGVPTIFYPSVLFEQEEQKNAQNHFNCPIVQSYPEVLKNNIDEIREGQVNYLHPFINL
ANPDGVAVNIHKSLTAQGFTVSLEEVEAAVQHGFEEMDKFKEDLRLKAEDLLMQINLNNEKAIVLAGRPYHLDPEINHGI
ADIITQEGFHVLTEDSISHLAEVSGLRVVNQWVYHSRLYAAANVVCKNKNLELVQLNSFGCGLDAVTTDQVEEIMRGHNK
LYTVLKIDEGSNMGAVRIRLRSLKAAVSERTRHNIEVTTEVHELVPETPAFTKEMAKKHTLLLPMLSPIHQEGLLDTAFA
AAGYNVVSLPETNTSVNNGLKFVNNDSCYPAIITIGQLIEALQSGEYDLDNTSVMMTQTGGGCRATNYIPLLRKALIDAG
FPQVPVVSLSMGNQGTEKGFKFTVPLLTRFMIAVLYGDLFERVVYRTRPYEAVEGSVNDLHAKWLEKARKNVESGSIFEF
NRNMKKIVAEFDQIELLDIQKPRVGVVGEILVKYSKTANNDIVSIIEEEGGEAVVLDLIGFMNYSLYNQIWKADEIAFSK
KNKLMAKTFIGIINMLEKPMNKALKASNRFDSIESIYDVASSTEEVISIGNHTGEGWFLTGEMIELLQKGVNNIICLQPF
GCLPNHIVGKGMMKELRRQYPGANLAPIDYDPGVSAVNQLNRIRLMMTTAKKRMNKVSDSVEKSETESKLETAQAY
>Mature_1435_residues
TQIYKTGIDVGSTTVKLVVFDENYKLIFSRYERHFSDVKAATIKVFNDFIAEHGDLNLELAITGSGGMGLAEVIDVPFVQ
EVIASSITIEKFIPQTDVMIELGGEDAKMTFFDNGTQELRMNGTCAGGTGAFIDQMAALLKVDANGVNELAKNYEKLYPI
ASRCGVFAKTDVQPLLNEGVRREDIAASIFQAVVNQTIAGLASGRRIKGNVAFLGGPLFFMSELRKRFIETLDLKEENII
FPENPQLFVAMGAALYEETSQKTATELIHSLENDDSDSLIPQDTMDKLFENQAELDEFRARHAKATANYKELNEHHGAAF
LGIDAGSTTTKVVLIDGEGNILYDHYGSNNGEPLESVINILKDVYAKLPADVYIAKSTVTGYGEHLIKAGLHVDYGEVET
MAHYKAADYFNPGVDFILDIGGQDMKAMRIRDGALSSIQLNEACSSGCGSFIETFAHSLRHDVREFSQKALLAEHPVNLG
SRCTVFMNSKVKQVQKEGATVGDISAGLSYSVIKNALYKVIKVKRPEELGKKIVVQGGTFYNEAVLRAFEKISEREVVRP
SIAGLMGAYGCALISLDNEETHKESELLKLDELEKFTTHKEFMVCGLCENNCKMTLTVFNDGNKFVTGNRCERGAEKATK
VKVAKKDKKVNLVDYKYKKLFRYHSLSKKKQTRGEIGIPRVLNMYENYPLWHTMLTDLGFRVVLSPRSDKELFEEGIETI
PSDTVCYPAKMSHGHIMALIKQGVPTIFYPSVLFEQEEQKNAQNHFNCPIVQSYPEVLKNNIDEIREGQVNYLHPFINLA
NPDGVAVNIHKSLTAQGFTVSLEEVEAAVQHGFEEMDKFKEDLRLKAEDLLMQINLNNEKAIVLAGRPYHLDPEINHGIA
DIITQEGFHVLTEDSISHLAEVSGLRVVNQWVYHSRLYAAANVVCKNKNLELVQLNSFGCGLDAVTTDQVEEIMRGHNKL
YTVLKIDEGSNMGAVRIRLRSLKAAVSERTRHNIEVTTEVHELVPETPAFTKEMAKKHTLLLPMLSPIHQEGLLDTAFAA
AGYNVVSLPETNTSVNNGLKFVNNDSCYPAIITIGQLIEALQSGEYDLDNTSVMMTQTGGGCRATNYIPLLRKALIDAGF
PQVPVVSLSMGNQGTEKGFKFTVPLLTRFMIAVLYGDLFERVVYRTRPYEAVEGSVNDLHAKWLEKARKNVESGSIFEFN
RNMKKIVAEFDQIELLDIQKPRVGVVGEILVKYSKTANNDIVSIIEEEGGEAVVLDLIGFMNYSLYNQIWKADEIAFSKK
NKLMAKTFIGIINMLEKPMNKALKASNRFDSIESIYDVASSTEEVISIGNHTGEGWFLTGEMIELLQKGVNNIICLQPFG
CLPNHIVGKGMMKELRRQYPGANLAPIDYDPGVSAVNQLNRIRLMMTTAKKRMNKVSDSVEKSETESKLETAQAY

Specific function: Required for the activation of (R)-2-hydroxyglutaryl-CoA dehydratase. This protein is extremely sensitive towards oxygen [H]

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiL and M.jannaschii MJ0004 and MJ0800 [H]

Homologues:

Organism=Escherichia coli, GI87082426, Length=257, Percent_Identity=25.6809338521401, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 159779; Mature: 159648

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQIYKTGIDVGSTTVKLVVFDENYKLIFSRYERHFSDVKAATIKVFNDFIAEHGDLNLE
CCCCEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LAITGSGGMGLAEVIDVPFVQEVIASSITIEKFIPQTDVMIELGGEDAKMTFFDNGTQEL
EEEECCCCCCHHHHHCCHHHHHHHHHHCHHHHHCCCCCEEEEECCCCCEEEEEECCCCEE
RMNGTCAGGTGAFIDQMAALLKVDANGVNELAKNYEKLYPIASRCGVFAKTDVQPLLNEG
EECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHCC
VRREDIAASIFQAVVNQTIAGLASGRRIKGNVAFLGGPLFFMSELRKRFIETLDLKEENI
CCHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECCHHHHHHHHHHHHHHHHCCCCCCE
IFPENPQLFVAMGAALYEETSQKTATELIHSLENDDSDSLIPQDTMDKLFENQAELDEFR
ECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHH
ARHAKATANYKELNEHHGAAFLGIDAGSTTTKVVLIDGEGNILYDHYGSNNGEPLESVIN
HHHHHHCCCHHHHHHCCCEEEEEECCCCCEEEEEEEECCCCEEEEECCCCCCCHHHHHHH
ILKDVYAKLPADVYIAKSTVTGYGEHLIKAGLHVDYGEVETMAHYKAADYFNPGVDFILD
HHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEE
IGGQDMKAMRIRDGALSSIQLNEACSSGCGSFIETFAHSLRHDVREFSQKALLAEHPVNL
CCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSRCTVFMNSKVKQVQKEGATVGDISAGLSYSVIKNALYKVIKVKRPEELGKKIVVQGGT
CCEEEEEECHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHCCCHHHHCCEEEEECCC
FYNEAVLRAFEKISEREVVRPSIAGLMGAYGCALISLDNEETHKESELLKLDELEKFTTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHCC
KEFMVCGLCENNCKMTLTVFNDGNKFVTGNRCERGAEKATKVKVAKKDKKVNLVDYKYKK
CCEEEEEEECCCCEEEEEEEECCCEEEECCHHHHHHHHHHHEEEECCCCCEEEEHHHHHH
LFRYHSLSKKKQTRGEIGIPRVLNMYENYPLWHTMLTDLGFRVVLSPRSDKELFEEGIET
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
IPSDTVCYPAKMSHGHIMALIKQGVPTIFYPSVLFEQEEQKNAQNHFNCPIVQSYPEVLK
CCCCCEEECCCCCCCHHHHHHHCCCCCEECCHHHHCCHHHHCHHHCCCCCHHHHHHHHHH
NNIDEIREGQVNYLHPFINLANPDGVAVNIHKSLTAQGFTVSLEEVEAAVQHGFEEMDKF
CCHHHHHCCCCEEEEHHHCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHCHHHHHHH
KEDLRLKAEDLLMQINLNNEKAIVLAGRPYHLDPEINHGIADIITQEGFHVLTEDSISHL
HHHHCCCHHHEEEEEECCCCEEEEEECCCEECCCCCCCCHHHHHHCCCCEEEEHHHHHHH
AEVSGLRVVNQWVYHSRLYAAANVVCKNKNLELVQLNSFGCGLDAVTTDQVEEIMRGHNK
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCE
LYTVLKIDEGSNMGAVRIRLRSLKAAVSERTRHNIEVTTEVHELVPETPAFTKEMAKKHT
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCHHHHHHHHHHE
LLLPMLSPIHQEGLLDTAFAAAGYNVVSLPETNTSVNNGLKFVNNDSCYPAIITIGQLIE
EHHHHHHHHHHCCCHHHHHHHCCCCEEECCCCCCCHHCCCEECCCCCCHHHHHHHHHHHH
ALQSGEYDLDNTSVMMTQTGGGCRATNYIPLLRKALIDAGFPQVPVVSLSMGNQGTEKGF
HHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
KFTVPLLTRFMIAVLYGDLFERVVYRTRPYEAVEGSVNDLHAKWLEKARKNVESGSIFEF
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCEEEE
NRNMKKIVAEFDQIELLDIQKPRVGVVGEILVKYSKTANNDIVSIIEEEGGEAVVLDLIG
CCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEHHHHH
FMNYSLYNQIWKADEIAFSKKNKLMAKTFIGIINMLEKPMNKALKASNRFDSIESIYDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SSTEEVISIGNHTGEGWFLTGEMIELLQKGVNNIICLQPFGCLPNHIVGKGMMKELRRQY
CCHHHHHHCCCCCCCCEEECHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHC
PGANLAPIDYDPGVSAVNQLNRIRLMMTTAKKRMNKVSDSVEKSETESKLETAQAY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQIYKTGIDVGSTTVKLVVFDENYKLIFSRYERHFSDVKAATIKVFNDFIAEHGDLNLE
CCCEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LAITGSGGMGLAEVIDVPFVQEVIASSITIEKFIPQTDVMIELGGEDAKMTFFDNGTQEL
EEEECCCCCCHHHHHCCHHHHHHHHHHCHHHHHCCCCCEEEEECCCCCEEEEEECCCCEE
RMNGTCAGGTGAFIDQMAALLKVDANGVNELAKNYEKLYPIASRCGVFAKTDVQPLLNEG
EECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHCC
VRREDIAASIFQAVVNQTIAGLASGRRIKGNVAFLGGPLFFMSELRKRFIETLDLKEENI
CCHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEECCHHHHHHHHHHHHHHHHCCCCCCE
IFPENPQLFVAMGAALYEETSQKTATELIHSLENDDSDSLIPQDTMDKLFENQAELDEFR
ECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHH
ARHAKATANYKELNEHHGAAFLGIDAGSTTTKVVLIDGEGNILYDHYGSNNGEPLESVIN
HHHHHHCCCHHHHHHCCCEEEEEECCCCCEEEEEEEECCCCEEEEECCCCCCCHHHHHHH
ILKDVYAKLPADVYIAKSTVTGYGEHLIKAGLHVDYGEVETMAHYKAADYFNPGVDFILD
HHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEE
IGGQDMKAMRIRDGALSSIQLNEACSSGCGSFIETFAHSLRHDVREFSQKALLAEHPVNL
CCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSRCTVFMNSKVKQVQKEGATVGDISAGLSYSVIKNALYKVIKVKRPEELGKKIVVQGGT
CCEEEEEECHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHHHCCCHHHHCCEEEEECCC
FYNEAVLRAFEKISEREVVRPSIAGLMGAYGCALISLDNEETHKESELLKLDELEKFTTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHCC
KEFMVCGLCENNCKMTLTVFNDGNKFVTGNRCERGAEKATKVKVAKKDKKVNLVDYKYKK
CCEEEEEEECCCCEEEEEEEECCCEEEECCHHHHHHHHHHHEEEECCCCCEEEEHHHHHH
LFRYHSLSKKKQTRGEIGIPRVLNMYENYPLWHTMLTDLGFRVVLSPRSDKELFEEGIET
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHH
IPSDTVCYPAKMSHGHIMALIKQGVPTIFYPSVLFEQEEQKNAQNHFNCPIVQSYPEVLK
CCCCCEEECCCCCCCHHHHHHHCCCCCEECCHHHHCCHHHHCHHHCCCCCHHHHHHHHHH
NNIDEIREGQVNYLHPFINLANPDGVAVNIHKSLTAQGFTVSLEEVEAAVQHGFEEMDKF
CCHHHHHCCCCEEEEHHHCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHCHHHHHHH
KEDLRLKAEDLLMQINLNNEKAIVLAGRPYHLDPEINHGIADIITQEGFHVLTEDSISHL
HHHHCCCHHHEEEEEECCCCEEEEEECCCEECCCCCCCCHHHHHHCCCCEEEEHHHHHHH
AEVSGLRVVNQWVYHSRLYAAANVVCKNKNLELVQLNSFGCGLDAVTTDQVEEIMRGHNK
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCE
LYTVLKIDEGSNMGAVRIRLRSLKAAVSERTRHNIEVTTEVHELVPETPAFTKEMAKKHT
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHCCCCCHHHHHHHHHHE
LLLPMLSPIHQEGLLDTAFAAAGYNVVSLPETNTSVNNGLKFVNNDSCYPAIITIGQLIE
EHHHHHHHHHHCCCHHHHHHHCCCCEEECCCCCCCHHCCCEECCCCCCHHHHHHHHHHHH
ALQSGEYDLDNTSVMMTQTGGGCRATNYIPLLRKALIDAGFPQVPVVSLSMGNQGTEKGF
HHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
KFTVPLLTRFMIAVLYGDLFERVVYRTRPYEAVEGSVNDLHAKWLEKARKNVESGSIFEF
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCEEEE
NRNMKKIVAEFDQIELLDIQKPRVGVVGEILVKYSKTANNDIVSIIEEEGGEAVVLDLIG
CCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEHHHHH
FMNYSLYNQIWKADEIAFSKKNKLMAKTFIGIINMLEKPMNKALKASNRFDSIESIYDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SSTEEVISIGNHTGEGWFLTGEMIELLQKGVNNIICLQPFGCLPNHIVGKGMMKELRRQY
CCHHHHHHCCCCCCCCEEECHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHC
PGANLAPIDYDPGVSAVNQLNRIRLMMTTAKKRMNKVSDSVEKSETESKLETAQAY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8365476; 2659350; 7607244; 11106419; 11243821 [H]