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The map label for this gene is tsf [H]

Identifier: 125625187

GI number: 125625187

Start: 2379473

End: 2380501

Strand: Reverse

Name: tsf [H]

Synonym: llmg_2429

Alternate gene names: 125625187

Gene position: 2380501-2379473 (Counterclockwise)

Preceding gene: 125625188

Following gene: 125625186

Centisome position: 94.11

GC content: 39.55

Gene sequence:

>1029_bases
ATGGCAGTAACAGCAGCTCAAGTAAAAGAATTACGTGAAAAAACTGGTGCAGGAATTATGGACGCTAAACGTGCGCTCGT
AGAAACTGACGGAAATATGGAAGCAGCAGCAGAACTTCTTCGTGAAAAAGGAATCGCTAAAGCAGCTAAAAAAGCTGACC
GCGTTGCCGCTGAAGGACTTACAGGAATTGCTGTAAATGGAAATGTTGCAGCACTTGTTGAGTTGAATTCAGAAACAGAC
TTTGTTGCGAAAAATGACCAATTTGTTGCTTTGGTTAAAGAAACTGCAGAACTTCTTGCAGCTAGCAAACCAGCAAACAA
TGAAGAAGCGTTGGCTATCAAAACAGCTTCAGGCGTAACTCTTGAACAAGAACTTGTTCAAGCAACTGCAACAATCGGAG
AAAAAATCACTTTCCGTCGTTTTGTAGTAATTGAAAAAACTGATGCGCAACACTTTGGCGCATACCAACATAACGGTGGT
AAAATTGGGGTTATTTCAGTTATTGAAGGTGCTGACGAAACACTTGCTAAACAAGTATCAATGCACATTGCCGCTATGAA
CCCAACAGTTCTTTCTGCTGATGAACTTGATTCAGAATTTGTAAAAGCTGAATTAGCACAAATGAACCACAAAATTGATG
AAGACAACGCTAGCCGTGTACTCGTTAACAAACCAGAACTTCCACATCATGAATATGGTTCTAAGAGCCAATTGACAGAA
GAAGTTCTTGCAGCAGCAAAAGCTTCATTTGAAGAAGAACTTAAAGCTGAAGGCAAACCAGAAAAAATCTGGGACAAAAT
CCTTCCAGGTAAAATGGCTAAATTTATCGTTGACAACACAAAAGTTGACCAACAATTTGCTCTTCTTGCACAACTTTACA
TCATGGATGATAGTAAAACTGTTGAAGCTTTCCTTGAATCTAAAGGTGCTAAAGCAATTGCATTCACACGTTTTGAAGTT
GGTGAAGGAATTGAAAAAGCTGAAACAGACTTCGCAGCTGAAGTTGAAGCAGCAAAAGCAGGACTTTAA

Upstream 100 bases:

>100_bases
AATTAAGTAACTACAACAGGCGAGGCCTTACGCCTCACCTGTTTTTTTAAATAAAACTACTGTCAATATTGACAGAATAA
ACACATAGGAGATTTACAAA

Downstream 100 bases:

>100_bases
TTTAATAAAAGGAGCAACCAAATTAGTGGTTGCTTTTTTTTTGAAAAAGAAAAAAGGATTTACAACTAGAAAACTAAGAA
AATAGTGTATTTCTTTGAAG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGLTGIAVNGNVAALVELNSETD
FVAKNDQFVALVKETAELLAASKPANNEEALAIKTASGVTLEQELVQATATIGEKITFRRFVVIEKTDAQHFGAYQHNGG
KIGVISVIEGADETLAKQVSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEYGSKSQLTE
EVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEV
GEGIEKAETDFAAEVEAAKAGL

Sequences:

>Translated_342_residues
MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGLTGIAVNGNVAALVELNSETD
FVAKNDQFVALVKETAELLAASKPANNEEALAIKTASGVTLEQELVQATATIGEKITFRRFVVIEKTDAQHFGAYQHNGG
KIGVISVIEGADETLAKQVSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEYGSKSQLTE
EVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEV
GEGIEKAETDFAAEVEAAKAGL
>Mature_341_residues
AVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGLTGIAVNGNVAALVELNSETDF
VAKNDQFVALVKETAELLAASKPANNEEALAIKTASGVTLEQELVQATATIGEKITFRRFVVIEKTDAQHFGAYQHNGGK
IGVISVIEGADETLAKQVSMHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEYGSKSQLTEE
VLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKTVEAFLESKGAKAIAFTRFEVG
EGIEKAETDFAAEVEAAKAGL

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=225, Percent_Identity=28.4444444444444, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1786366, Length=335, Percent_Identity=36.7164179104478, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17561440, Length=211, Percent_Identity=27.9620853080569, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19921466, Length=212, Percent_Identity=31.1320754716981, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 36740; Mature: 36609

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGL
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
TGIAVNGNVAALVELNSETDFVAKNDQFVALVKETAELLAASKPANNEEALAIKTASGVT
CEEEECCCEEEEEEECCCCCEEECCCCEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
LEQELVQATATIGEKITFRRFVVIEKTDAQHFGAYQHNGGKIGVISVIEGADETLAKQVS
HHHHHHHHHHHHCCCEEEEEEEEEEECCHHHCCCEECCCCCEEEEEEECCCHHHHHHHHH
MHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEYGSKSQLTE
HHHEECCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHH
EVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKT
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEECCCHH
VEAFLESKGAKAIAFTRFEVGEGIEKAETDFAAEVEAAKAGL
HHHHHHCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVTAAQVKELREKTGAGIMDAKRALVETDGNMEAAAELLREKGIAKAAKKADRVAAEGL
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
TGIAVNGNVAALVELNSETDFVAKNDQFVALVKETAELLAASKPANNEEALAIKTASGVT
CEEEECCCEEEEEEECCCCCEEECCCCEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
LEQELVQATATIGEKITFRRFVVIEKTDAQHFGAYQHNGGKIGVISVIEGADETLAKQVS
HHHHHHHHHHHHCCCEEEEEEEEEEECCHHHCCCEECCCCCEEEEEEECCCHHHHHHHHH
MHIAAMNPTVLSADELDSEFVKAELAQMNHKIDEDNASRVLVNKPELPHHEYGSKSQLTE
HHHEECCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHH
EVLAAAKASFEEELKAEGKPEKIWDKILPGKMAKFIVDNTKVDQQFALLAQLYIMDDSKT
HHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEECCCHH
VEAFLESKGAKAIAFTRFEVGEGIEKAETDFAAEVEAAKAGL
HHHHHHCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]