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The map label for this gene is murM [H]

Identifier: 125625113

GI number: 125625113

Start: 2309043

End: 2310233

Strand: Reverse

Name: murM [H]

Synonym: llmg_2352

Alternate gene names: 125625113

Gene position: 2310233-2309043 (Counterclockwise)

Preceding gene: 125625114

Following gene: 125625112

Centisome position: 91.33

GC content: 32.16

Gene sequence:

>1191_bases
ATGAATGAATATACATCAAGAGAGTTTGAATTCAAAAGCATCGTAGACTTGGAAAAGGTTGAAAACTTCATACTCAAGTC
ACCGCTTTTTGATATTTTGCAGACGCCATCATGGAGAAATGTTAAAGATGAATGGAAGTCAGAATTTTTAGGATTTACGG
AAAAAGGGGAGACAGAACTTTTAGCTTCTTGTTTAGTACTGACGCGTTCTTTACCTCTGGGTTTTAAAATGTGCTATATT
CCACGAGGCATTATCATGGATTATTCCGACGATGAGCTTTTAAGCTTTGTTGTTTTGAAGTTGAAAGAATATGGTAAGAA
AGAAAAGGCGCTTTTTATTAAATTTGACCCGCTTATTGAAGAGAATTCGGAGGGAAAGCGACTTATTGAAAAGTTGGCTC
TATTAGGAGTGGCTTATGGAGGAAGAACAAAAGAAATTCATGAAACAATTCAATTTCGTTTTGATGCCACAATCTATAGA
GACGATTATAGCTACGAGAAACTATCAAAAAAGTTTAATAGTCGATTAAATAAAGCCAAAAAAGCCTTTCCTGAAATCAA
GATTGGTCAAGAAGAATATAGTGAGGATTTTGCTCGCTTAATGACATTAACAGAGACAAGAAAAGTTATAAATTTAAGAG
ATAAAGCATATTTTGAAAAAATTCTAGCTGCTTTTCCCAAAAATTCTGCTATTGTTATTGTTTATACAAATGTTAAAGAA
CTTTTGGATGAAGTAAAGACCGAAACTTTGAAATTATCAAAAAGAATCAAAGATATAAGTAATGAAAAGAAAAAAGTTCT
TTTAGAACATCAACTTCTTGAAAAAAAGGATGAGGTGAATGATTTAGAACAAATCATAAAAACTTCGGGAGAAATTGTCC
CAAGTGCAGGAAATTTAATAATATATTATGGTGAAAAGTCATACAACTTGTATGCAGGGATGGATGATGCTTTCAAAAAA
TATTATGTTTCTTATCTTTCTTGGGATGAAAGTATAAAGTATAGCTTTCTAAAAGGAGCTTTGATGCATGATATGGGGGG
AGTAGAGGCAGATTCTGGAGGTTTACGCTCTTTTAAAAAAATGTTTAATCCTTCCTTTAAGGAATATGTTGGAGAATTTG
ATATTCCTACAAATAGACTTCTTTATCCTCTAATCAAACGACTCTATAAAATGCGAAAGGATAAAAAGTAG

Upstream 100 bases:

>100_bases
TTATGAAATAGTATGGAGTGATTGAAAGCTTTAGTGGTAACCTTTTACCAAGACAAAATGAGAGCAGCAAAATTTAAAAA
ATTAGAAATTAATATATTTT

Downstream 100 bases:

>100_bases
AGAATTATGCCTAAAATAAGCATTATTGTTCCAGTTTATAATAGCGCCCTCTTTTTAGAAAGATATTTAGATTCGATTAT
TAATCAGACTTTTCAGGATT

Product: putative peptidoglycan branched peptide synthesis protein

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance X [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNEYTSREFEFKSIVDLEKVENFILKSPLFDILQTPSWRNVKDEWKSEFLGFTEKGETELLASCLVLTRSLPLGFKMCYI
PRGIIMDYSDDELLSFVVLKLKEYGKKEKALFIKFDPLIEENSEGKRLIEKLALLGVAYGGRTKEIHETIQFRFDATIYR
DDYSYEKLSKKFNSRLNKAKKAFPEIKIGQEEYSEDFARLMTLTETRKVINLRDKAYFEKILAAFPKNSAIVIVYTNVKE
LLDEVKTETLKLSKRIKDISNEKKKVLLEHQLLEKKDEVNDLEQIIKTSGEIVPSAGNLIIYYGEKSYNLYAGMDDAFKK
YYVSYLSWDESIKYSFLKGALMHDMGGVEADSGGLRSFKKMFNPSFKEYVGEFDIPTNRLLYPLIKRLYKMRKDKK

Sequences:

>Translated_396_residues
MNEYTSREFEFKSIVDLEKVENFILKSPLFDILQTPSWRNVKDEWKSEFLGFTEKGETELLASCLVLTRSLPLGFKMCYI
PRGIIMDYSDDELLSFVVLKLKEYGKKEKALFIKFDPLIEENSEGKRLIEKLALLGVAYGGRTKEIHETIQFRFDATIYR
DDYSYEKLSKKFNSRLNKAKKAFPEIKIGQEEYSEDFARLMTLTETRKVINLRDKAYFEKILAAFPKNSAIVIVYTNVKE
LLDEVKTETLKLSKRIKDISNEKKKVLLEHQLLEKKDEVNDLEQIIKTSGEIVPSAGNLIIYYGEKSYNLYAGMDDAFKK
YYVSYLSWDESIKYSFLKGALMHDMGGVEADSGGLRSFKKMFNPSFKEYVGEFDIPTNRLLYPLIKRLYKMRKDKK
>Mature_396_residues
MNEYTSREFEFKSIVDLEKVENFILKSPLFDILQTPSWRNVKDEWKSEFLGFTEKGETELLASCLVLTRSLPLGFKMCYI
PRGIIMDYSDDELLSFVVLKLKEYGKKEKALFIKFDPLIEENSEGKRLIEKLALLGVAYGGRTKEIHETIQFRFDATIYR
DDYSYEKLSKKFNSRLNKAKKAFPEIKIGQEEYSEDFARLMTLTETRKVINLRDKAYFEKILAAFPKNSAIVIVYTNVKE
LLDEVKTETLKLSKRIKDISNEKKKVLLEHQLLEKKDEVNDLEQIIKTSGEIVPSAGNLIIYYGEKSYNLYAGMDDAFKK
YYVSYLSWDESIKYSFLKGALMHDMGGVEADSGGLRSFKKMFNPSFKEYVGEFDIPTNRLLYPLIKRLYKMRKDKK

Specific function: Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 46251; Mature: 46251

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEYTSREFEFKSIVDLEKVENFILKSPLFDILQTPSWRNVKDEWKSEFLGFTEKGETEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHH
LASCLVLTRSLPLGFKMCYIPRGIIMDYSDDELLSFVVLKLKEYGKKEKALFIKFDPLIE
HHHHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
ENSEGKRLIEKLALLGVAYGGRTKEIHETIQFRFDATIYRDDYSYEKLSKKFNSRLNKAK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHH
KAFPEIKIGQEEYSEDFARLMTLTETRKVINLRDKAYFEKILAAFPKNSAIVIVYTNVKE
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
LLDEVKTETLKLSKRIKDISNEKKKVLLEHQLLEKKDEVNDLEQIIKTSGEIVPSAGNLI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEE
IYYGEKSYNLYAGMDDAFKKYYVSYLSWDESIKYSFLKGALMHDMGGVEADSGGLRSFKK
EEECCCCCEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
MFNPSFKEYVGEFDIPTNRLLYPLIKRLYKMRKDKK
HHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNEYTSREFEFKSIVDLEKVENFILKSPLFDILQTPSWRNVKDEWKSEFLGFTEKGETEL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHH
LASCLVLTRSLPLGFKMCYIPRGIIMDYSDDELLSFVVLKLKEYGKKEKALFIKFDPLIE
HHHHHHHHHCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
ENSEGKRLIEKLALLGVAYGGRTKEIHETIQFRFDATIYRDDYSYEKLSKKFNSRLNKAK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHH
KAFPEIKIGQEEYSEDFARLMTLTETRKVINLRDKAYFEKILAAFPKNSAIVIVYTNVKE
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHH
LLDEVKTETLKLSKRIKDISNEKKKVLLEHQLLEKKDEVNDLEQIIKTSGEIVPSAGNLI
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEE
IYYGEKSYNLYAGMDDAFKKYYVSYLSWDESIKYSFLKGALMHDMGGVEADSGGLRSFKK
EEECCCCCEEEECCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
MFNPSFKEYVGEFDIPTNRLLYPLIKRLYKMRKDKK
HHCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA