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The map label for this gene is dinP

Identifier: 125625067

GI number: 125625067

Start: 2253706

End: 2254800

Strand: Reverse

Name: dinP

Synonym: llmg_2305

Alternate gene names: 125625067

Gene position: 2254800-2253706 (Counterclockwise)

Preceding gene: 125625068

Following gene: 125625065

Centisome position: 89.14

GC content: 36.89

Gene sequence:

>1095_bases
ATGCTAACTTTTCCACTGATCAATGACACTTCACGAAAAATCATTCATATCGATATGGATGCCTTTTTTGCTTCCGTTGA
AGTGCGTGATAATCCGAGTCTAAAGGGTAAACCAGTTGTGATTGCTAGGAATCCATTGCAGACTGGTGGGCGGGGAGTTG
TATCAACTTGTTCTTATGAAGCGCGTGCTTTTGGAATACACTCGGCAATGAGTGCAAAGGAAGCGTATGACCTTTGTCCA
CAAGCTATTTTTATTTCTGGGAACTATGAGAAATATACAAAAGTTAGTAAACAAGTTCGTGAAATTTTTAAACGCTACAC
GGATAATATTGAGGCAGCGTCAATTGATGAAGCCTATTTAGATGTAACCGAGAATAAAATAGGAGCTCAATCAGCAATAA
AAATAGCAAAATTAATTCAACATGATATCTTTGTTGAACTAGGTTTGACTTGTTCAGCAGGAGTTTCTTATAATAAATTT
TTGGCAAAGATTGCTTCAGATTATGAAAAGCCACATGGTTTGACATTAATTATGCCAGATGAAGCATTAGAGTTTTTGGC
AAAGTTGCCTGTGGAAAAATTTCATGGGGTGGGGAAAGCAACTGTTCCTAAATTACATGCCTTAGGATTCTTTACTGGAG
GAGATTTACAAAAAGCTGATCCGGTTGATTTGGCTGAAAGATTTGGTATTTATGGTTGGGAACTTTTCCAAAAGGCAAAT
GGAATTCATAACTCTAAAGTCAAAAATCATCGTGAACGAAAATCAGTAGGCAAAGAGCGAACCTACGGGAAATTACTATA
TCTTCCAGATGATATCAAAGCTGAATTAATCAAAATATCTAAACAGGTTTCTGAATCCTTAAAAAGGCACCAACTCAAGG
GAAACATTATTATTTTGAAATTGAGATATTCGGATTTTACAACACTAACGAAACGAAAATCAATGGTAGAGAATCTGGAT
AGTCCGGAGGACATTGCAGAAGCTGCACGACAGATATTTGAAGAAATTGATTATGATGAGAGCTTGGGAGTTAGGCTGCT
AGGAGTTACCGTATCAGGATTTGGTGTCCAAAAAGCAACATTAGATATGCAATAG

Upstream 100 bases:

>100_bases
TGATTATCAAATTATTAATTTATAAATTAAAACTCTTGCTCGTCAAGAGTTTTTTTATTCGCCTATTGAGTCTAAAAACT
AATTTTTGTATAATAACAAT

Downstream 100 bases:

>100_bases
TTAGAAAAGGGATGAAGGCAATTTCGTCTCGTTTTTTTATCATTAAATAATAGATAATTCCAAGTAAACAAGCGATTTGA
AGAAGTTTCATTTCATCAAA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKGKPVVIARNPLQTGGRGVVSTCSYEARAFGIHSAMSAKEAYDLCP
QAIFISGNYEKYTKVSKQVREIFKRYTDNIEAASIDEAYLDVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKF
LAKIASDYEKPHGLTLIMPDEALEFLAKLPVEKFHGVGKATVPKLHALGFFTGGDLQKADPVDLAERFGIYGWELFQKAN
GIHNSKVKNHRERKSVGKERTYGKLLYLPDDIKAELIKISKQVSESLKRHQLKGNIIILKLRYSDFTTLTKRKSMVENLD
SPEDIAEAARQIFEEIDYDESLGVRLLGVTVSGFGVQKATLDMQ

Sequences:

>Translated_364_residues
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKGKPVVIARNPLQTGGRGVVSTCSYEARAFGIHSAMSAKEAYDLCP
QAIFISGNYEKYTKVSKQVREIFKRYTDNIEAASIDEAYLDVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKF
LAKIASDYEKPHGLTLIMPDEALEFLAKLPVEKFHGVGKATVPKLHALGFFTGGDLQKADPVDLAERFGIYGWELFQKAN
GIHNSKVKNHRERKSVGKERTYGKLLYLPDDIKAELIKISKQVSESLKRHQLKGNIIILKLRYSDFTTLTKRKSMVENLD
SPEDIAEAARQIFEEIDYDESLGVRLLGVTVSGFGVQKATLDMQ
>Mature_364_residues
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKGKPVVIARNPLQTGGRGVVSTCSYEARAFGIHSAMSAKEAYDLCP
QAIFISGNYEKYTKVSKQVREIFKRYTDNIEAASIDEAYLDVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKF
LAKIASDYEKPHGLTLIMPDEALEFLAKLPVEKFHGVGKATVPKLHALGFFTGGDLQKADPVDLAERFGIYGWELFQKAN
GIHNSKVKNHRERKSVGKERTYGKLLYLPDDIKAELIKISKQVSESLKRHQLKGNIIILKLRYSDFTTLTKRKSMVENLD
SPEDIAEAARQIFEEIDYDESLGVRLLGVTVSGFGVQKATLDMQ

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=340, Percent_Identity=30.5882352941176, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI7706681, Length=341, Percent_Identity=30.4985337243402, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI154350220, Length=298, Percent_Identity=28.8590604026846, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI7705344, Length=115, Percent_Identity=47.8260869565217, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI5729982, Length=119, Percent_Identity=42.0168067226891, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=42.6934097421203, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1787432, Length=213, Percent_Identity=29.1079812206573, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193205700, Length=405, Percent_Identity=28.1481481481481, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17537959, Length=310, Percent_Identity=27.4193548387097, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI193205702, Length=339, Percent_Identity=27.1386430678466, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534089, Length=369, Percent_Identity=26.5582655826558, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI19923006, Length=345, Percent_Identity=26.6666666666667, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21355641, Length=286, Percent_Identity=27.972027972028, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644984, Length=286, Percent_Identity=27.972027972028, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24668444, Length=127, Percent_Identity=35.4330708661417, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_LACLM (A2RNH9)

Other databases:

- EMBL:   AM406671
- RefSeq:   YP_001033550.1
- ProteinModelPortal:   A2RNH9
- SMR:   A2RNH9
- STRING:   A2RNH9
- GeneID:   4799035
- GenomeReviews:   AM406671_GR
- KEGG:   llm:llmg_2305
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   VICAASY
- ProtClustDB:   PRK02406
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 40624; Mature: 40624

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKGKPVVIARNPLQTGGRGVVSTCSYE
CEEECCCCCCCCEEEEEEHHHEEEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEECCCH
ARAFGIHSAMSAKEAYDLCPQAIFISGNYEKYTKVSKQVREIFKRYTDNIEAASIDEAYL
HHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
DVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKFLAKIASDYEKPHGLTLIMPD
HHHCCCCCHHHHHHHHHHHHHHHHEEECCEECCCCCHHHHHHHHHHHCCCCCCEEEEECH
EALEFLAKLPVEKFHGVGKATVPKLHALGFFTGGDLQKADPVDLAERFGIYGWELFQKAN
HHHHHHHHCCHHHHCCCCCCCCCHHHHEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHC
GIHNSKVKNHRERKSVGKERTYGKLLYLPDDIKAELIKISKQVSESLKRHQLKGNIIILK
CCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LRYSDFTTLTKRKSMVENLDSPEDIAEAARQIFEEIDYDESLGVRLLGVTVSGFGVQKAT
EECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEE
LDMQ
ECCC
>Mature Secondary Structure
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKGKPVVIARNPLQTGGRGVVSTCSYE
CEEECCCCCCCCEEEEEEHHHEEEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEECCCH
ARAFGIHSAMSAKEAYDLCPQAIFISGNYEKYTKVSKQVREIFKRYTDNIEAASIDEAYL
HHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
DVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKFLAKIASDYEKPHGLTLIMPD
HHHCCCCCHHHHHHHHHHHHHHHHEEECCEECCCCCHHHHHHHHHHHCCCCCCEEEEECH
EALEFLAKLPVEKFHGVGKATVPKLHALGFFTGGDLQKADPVDLAERFGIYGWELFQKAN
HHHHHHHHCCHHHHCCCCCCCCCHHHHEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHC
GIHNSKVKNHRERKSVGKERTYGKLLYLPDDIKAELIKISKQVSESLKRHQLKGNIIILK
CCCCHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LRYSDFTTLTKRKSMVENLDSPEDIAEAARQIFEEIDYDESLGVRLLGVTVSGFGVQKAT
EECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEE
LDMQ
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA