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The map label for this gene is frr [H]

Identifier: 125625049

GI number: 125625049

Start: 2239114

End: 2239671

Strand: Reverse

Name: frr [H]

Synonym: llmg_2284

Alternate gene names: 125625049

Gene position: 2239671-2239114 (Counterclockwise)

Preceding gene: 125625050

Following gene: 125625048

Centisome position: 88.54

GC content: 38.89

Gene sequence:

>558_bases
ATGGCAAACGAAATTGTTACAACAGCTCAAGAACGGATGAAACACTCATTAGCAAGTTTACAACGTGATTTGGGACACCT
CCGAGCTGGTCGTGCCAATGCAAGTCTTCTTGATCGTGTTCAAGTTGTTTACTATGGTGCACCAACACCACTTAATCAGT
TAGCGTCAATCACAATTCCAGAAGCTCGTGTCTTGATGGTGACTCCTTTTGACAAATCAATTTTGAAAGACATTGAAAAA
GCATTGTATGAATCAGACCTTGGAATTACGCCAGCAAATGACGGTTCTGTCATTCGTTTAGTTATCCCAATGTTGACAGA
AGAACGCCGTCGCGAACTTGTCAAAGAAATGGGTAAATACATTGAATCAGCAAAAGTAGCGATCCGTAATATCCGTCGCG
ATGCAATGGATACTGCTAAAAAATCAGAAAAAGCAAAAGAAATCACAGAAGATGATCTTAAAGATCTTGAAAATGAGATT
CAAAAAGTGACTGATGATGCTGTAAAAGAAGCTGACAGATTGGCGTCAGTAAAAGAAAAAGAATTGTTGGATATCTAA

Upstream 100 bases:

>100_bases
ACTAGTATATTCGTAAACGTCAAAGGGGCAATGGCTAGCCTTTGGTAGAATTTCTGTCAGTAAAAATAAAAGAATTAATA
AAGTAGAAAAAGGAAATAAA

Downstream 100 bases:

>100_bases
AAAACCGACAAAAAAGTAATTTGAAAAAGCATTGACGGCTCCATTGAGCCGTTTTTACATCAAAGTTTTGTAAGGATAAT
AAGATTGAGAAAAGTGATAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MANEIVTTAQERMKHSLASLQRDLGHLRAGRANASLLDRVQVVYYGAPTPLNQLASITIPEARVLMVTPFDKSILKDIEK
ALYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKYIESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENEI
QKVTDDAVKEADRLASVKEKELLDI

Sequences:

>Translated_185_residues
MANEIVTTAQERMKHSLASLQRDLGHLRAGRANASLLDRVQVVYYGAPTPLNQLASITIPEARVLMVTPFDKSILKDIEK
ALYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKYIESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENEI
QKVTDDAVKEADRLASVKEKELLDI
>Mature_184_residues
ANEIVTTAQERMKHSLASLQRDLGHLRAGRANASLLDRVQVVYYGAPTPLNQLASITIPEARVLMVTPFDKSILKDIEKA
LYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKYIESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENEIQ
KVTDDAVKEADRLASVKEKELLDI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=175, Percent_Identity=32, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI291042689, Length=160, Percent_Identity=33.75, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=44.2622950819672, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20786; Mature: 20655

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANEIVTTAQERMKHSLASLQRDLGHLRAGRANASLLDRVQVVYYGAPTPLNQLASITIP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCHHHHHHCCCC
EARVLMVTPFDKSILKDIEKALYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKY
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENEIQKVTDDAVKEADRLASVKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLDI
HHCCC
>Mature Secondary Structure 
ANEIVTTAQERMKHSLASLQRDLGHLRAGRANASLLDRVQVVYYGAPTPLNQLASITIP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCHHHHHHCCCC
EARVLMVTPFDKSILKDIEKALYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKY
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENEIQKVTDDAVKEADRLASVKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLDI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]