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The map label for this gene is hit [H]

Identifier: 125625038

GI number: 125625038

Start: 2232315

End: 2232713

Strand: Direct

Name: hit [H]

Synonym: llmg_2273

Alternate gene names: 125625038

Gene position: 2232315-2232713 (Clockwise)

Preceding gene: 125625034

Following gene: 125625039

Centisome position: 88.25

GC content: 35.84

Gene sequence:

>399_bases
ATGGAAGATTGTATTTTTTGCAAAATTATTGCTGGTGAAATTCCAAGCACCAAAGTTTATGAAGATGATGATGTTGTTGC
TTTCCTTGATATTACTCAAACCACTAAGGGCCACACATTAGTTGTCCCCAAAAAACACTACCGCAACATTCTTGCGATGA
CAGGCGAGGAATCTGCTGAACTTTTTAGTAAAGTCCCTCAAATCGCCAGTAAACTTGTGGATAAACTTCATGCTAAAGGT
ATGAATATCTTACAAAATAATGAAGAAATCGCTGGGCAAACTGTTTTTCATACTCATATTCATTTGATTCCTCGTTATGA
TGAAAATGATGGTTTCATTGCAAAATTCACAGCCCATGATTATGATTTAGCCGAAATAGCCAAACAAATTAATGGCTGA

Upstream 100 bases:

>100_bases
CTGGGTTTTTTCTACTTTTTATACTATAATCTATAGTAGATTATAAAGTTTTAGACTTCTTTATCAGAAGTTACCGAATA
ATGCTGGAGGAATTATCGAA

Downstream 100 bases:

>100_bases
TAAAGGACGTGTCTATGTTTGAATTATTTAAAGACTTAAAGAAGTTAATGACTGACTTATCTGAGGAAGTCAACACAATG
AAAATAAATCTTGAGAGAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MEDCIFCKIIAGEIPSTKVYEDDDVVAFLDITQTTKGHTLVVPKKHYRNILAMTGEESAELFSKVPQIASKLVDKLHAKG
MNILQNNEEIAGQTVFHTHIHLIPRYDENDGFIAKFTAHDYDLAEIAKQING

Sequences:

>Translated_132_residues
MEDCIFCKIIAGEIPSTKVYEDDDVVAFLDITQTTKGHTLVVPKKHYRNILAMTGEESAELFSKVPQIASKLVDKLHAKG
MNILQNNEEIAGQTVFHTHIHLIPRYDENDGFIAKFTAHDYDLAEIAKQING
>Mature_132_residues
MEDCIFCKIIAGEIPSTKVYEDDDVVAFLDITQTTKGHTLVVPKKHYRNILAMTGEESAELFSKVPQIASKLVDKLHAKG
MNILQNNEEIAGQTVFHTHIHLIPRYDENDGFIAKFTAHDYDLAEIAKQING

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=102, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17506713, Length=102, Percent_Identity=36.2745098039216, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=125, Percent_Identity=40.8, Blast_Score=94, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28574010, Length=103, Percent_Identity=33.9805825242718, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24581222, Length=103, Percent_Identity=33.9805825242718, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 14827; Mature: 14827

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDCIFCKIIAGEIPSTKVYEDDDVVAFLDITQTTKGHTLVVPKKHYRNILAMTGEESAE
CCCEEEEEEEECCCCCCCEECCCCEEEEEEEECCCCCCEEEECHHHHHHEEEECCCHHHH
LFSKVPQIASKLVDKLHAKGMNILQNNEEIAGQTVFHTHIHLIPRYDENDGFIAKFTAHD
HHHHHHHHHHHHHHHHHHCCCCHHCCCCHHCCCEEEEEEEEEEECEECCCCEEEEEECCC
YDLAEIAKQING
CCHHHHHHHHCC
>Mature Secondary Structure
MEDCIFCKIIAGEIPSTKVYEDDDVVAFLDITQTTKGHTLVVPKKHYRNILAMTGEESAE
CCCEEEEEEEECCCCCCCEECCCCEEEEEEEECCCCCCEEEECHHHHHHEEEECCCHHHH
LFSKVPQIASKLVDKLHAKGMNILQNNEEIAGQTVFHTHIHLIPRYDENDGFIAKFTAHD
HHHHHHHHHHHHHHHHHHCCCCHHCCCCHHCCCEEEEEEEEEEECEECCCCEEEEEECCC
YDLAEIAKQING
CCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]