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The map label for this gene is galE [H]

Identifier: 125625000

GI number: 125625000

Start: 2194374

End: 2195354

Strand: Reverse

Name: galE [H]

Synonym: llmg_2233

Alternate gene names: 125625000

Gene position: 2195354-2194374 (Counterclockwise)

Preceding gene: 125625001

Following gene: 125624999

Centisome position: 86.79

GC content: 37.72

Gene sequence:

>981_bases
ATGACAGTTTTAGTACTTGGTGGAGCAGGATATGTAGGAAGCCATGCGGTAGATATGCTTGTTAATCGTGGTTACGATGT
GGCAGTTGTTGATAATTTAGTAACAGGTCATCGCGAGGCTGTGTCAGAAAAAGTACGTTTTTATGAGGGAGATGTACGGG
ACCATGCTTTCTTAGCTAGTGTTTTTGAAAAGGAAAATATTGAAGGAATTATGCATTTTTGCGCTTATTCATTAGTGGGT
GAGTCAATGCAAAAACCATTGATGTATTTCAATAACAATGTCGGCGGAGCTCAGGTGATTCTAGAAACAATGGAAGAATT
TGGTGTTAAGCATATTGTTTTCTCAAGTACCGCAGCTACTTTTGGTATTCCTGAGGAAAGTCCAATTTCTGAAAAAACAC
CACAAAAACCAATTAATCCTTACGGCGAAAGTAAATTAATCATGGAAAAAATGATGAAATGGCAATCGCAAGCCACAGAT
ATGACTTATGTTGCTCTGCGCTATTTCAATGTTGCTGGTGCCAAAGATGATGGGTCAATTGGTGAAGCCCATAAAAATGA
AACACATTTAATTCCAATTATCCTACAAACTGCACTTGGACAAAGAGAATTTATTACCATTTATGGTGATGATTATCAGA
CTCCTGATGGAACATGTATCCGTGATTATATTGATATGGAAGATTTGATTGAAGCACATATCAAAGCACTTGAATATCTT
AAATCTGGTGGGAAATCTGACCAATTTAATCTTGGCTCAAGTAAAGGTTATTCAAATCTTGAAGTGCTTGAAACAGCACG
AAAAGTAACAGGAAAAGAAATTCCAAGTCAAATGGGTGAACGTCGTCCTGGCGATCCAGATGAACTTGTAGCGGACTCAA
CAAAAGCCGGCGAAATTTTAGGATGGAAAGTAAAAAATGATTTGGAACACATCATTACAAATGCTTGGGAATGGCATCAA
AGTCATCCAAAAGGCTACTGA

Upstream 100 bases:

>100_bases
TTATTTAGTGGAGAAATTCTCTGATTATGAAATAAGAATGATTAGAAGTTGATACAAACTTAAAAAAATCTGATATAATA
AATAGAAAATGGAGGATCTT

Downstream 100 bases:

>100_bases
TTAATTATCTAAAATTCGAAAAGAAGCTCAATTTTTTGAGCTTTTTTTGTATGAAATCGTCATGAAAATGTAAATAAAAT
TGTGATAATTATTAATAAAA

Product: GalE protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTVLVLGGAGYVGSHAVDMLVNRGYDVAVVDNLVTGHREAVSEKVRFYEGDVRDHAFLASVFEKENIEGIMHFCAYSLVG
ESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAATFGIPEESPISEKTPQKPINPYGESKLIMEKMMKWQSQATD
MTYVALRYFNVAGAKDDGSIGEAHKNETHLIPIILQTALGQREFITIYGDDYQTPDGTCIRDYIDMEDLIEAHIKALEYL
KSGGKSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRPGDPDELVADSTKAGEILGWKVKNDLEHIITNAWEWHQ
SHPKGY

Sequences:

>Translated_326_residues
MTVLVLGGAGYVGSHAVDMLVNRGYDVAVVDNLVTGHREAVSEKVRFYEGDVRDHAFLASVFEKENIEGIMHFCAYSLVG
ESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAATFGIPEESPISEKTPQKPINPYGESKLIMEKMMKWQSQATD
MTYVALRYFNVAGAKDDGSIGEAHKNETHLIPIILQTALGQREFITIYGDDYQTPDGTCIRDYIDMEDLIEAHIKALEYL
KSGGKSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRPGDPDELVADSTKAGEILGWKVKNDLEHIITNAWEWHQ
SHPKGY
>Mature_325_residues
TVLVLGGAGYVGSHAVDMLVNRGYDVAVVDNLVTGHREAVSEKVRFYEGDVRDHAFLASVFEKENIEGIMHFCAYSLVGE
SMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAATFGIPEESPISEKTPQKPINPYGESKLIMEKMMKWQSQATDM
TYVALRYFNVAGAKDDGSIGEAHKNETHLIPIILQTALGQREFITIYGDDYQTPDGTCIRDYIDMEDLIEAHIKALEYLK
SGGKSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRPGDPDELVADSTKAGEILGWKVKNDLEHIITNAWEWHQS
HPKGY

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=39.2961876832845, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=39.2961876832845, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=39.2961876832845, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI42516563, Length=323, Percent_Identity=25.6965944272446, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7657641, Length=335, Percent_Identity=26.2686567164179, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI193211614, Length=252, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI8393516, Length=252, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=37.5, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=27.9005524861878, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI48994969, Length=354, Percent_Identity=26.8361581920904, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790049, Length=266, Percent_Identity=27.4436090225564, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=38.8405797101449, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=38.6167146974063, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17568069, Length=325, Percent_Identity=24.9230769230769, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17539532, Length=306, Percent_Identity=24.8366013071895, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=38.8888888888889, Blast_Score=237, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321437, Length=253, Percent_Identity=24.901185770751, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=38.4839650145773, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI21356223, Length=312, Percent_Identity=25.9615384615385, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36292; Mature: 36161

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVLGGAGYVGSHAVDMLVNRGYDVAVVDNLVTGHREAVSEKVRFYEGDVRDHAFLAS
CEEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VFEKENIEGIMHFCAYSLVGESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAAT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCC
FGIPEESPISEKTPQKPINPYGESKLIMEKMMKWQSQATDMTYVALRYFNVAGAKDDGSI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
GEAHKNETHLIPIILQTALGQREFITIYGDDYQTPDGTCIRDYIDMEDLIEAHIKALEYL
CCCCCCCCEEHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
KSGGKSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRPGDPDELVADSTKAGEIL
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEE
GWKVKNDLEHIITNAWEWHQSHPKGY
EEEHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVLVLGGAGYVGSHAVDMLVNRGYDVAVVDNLVTGHREAVSEKVRFYEGDVRDHAFLAS
EEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VFEKENIEGIMHFCAYSLVGESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAAT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCC
FGIPEESPISEKTPQKPINPYGESKLIMEKMMKWQSQATDMTYVALRYFNVAGAKDDGSI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
GEAHKNETHLIPIILQTALGQREFITIYGDDYQTPDGTCIRDYIDMEDLIEAHIKALEYL
CCCCCCCCEEHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
KSGGKSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRPGDPDELVADSTKAGEIL
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEE
GWKVKNDLEHIITNAWEWHQSHPKGY
EEEHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]