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The map label for this gene is mntA [H]

Identifier: 125624941

GI number: 125624941

Start: 2139888

End: 2141150

Strand: Reverse

Name: mntA [H]

Synonym: llmg_2171

Alternate gene names: 125624941

Gene position: 2141150-2139888 (Counterclockwise)

Preceding gene: 125624942

Following gene: 125624940

Centisome position: 84.65

GC content: 37.53

Gene sequence:

>1263_bases
ATGAAAAAGATAAAAATGAGGCGATTTTTACAAGATAAAAGACATCCTGCCCTTGATTTTTTGAAATATGTTGGTCCTGG
ATTAATTGTTGCGGTCGGCTTTATTGACCCTGGGAATTGGGCGGCTAACCTAGCAGCAGGCTCGCAATTTGGCTATAAAC
TACTCTGGGTAATCACTTTATCAACAATTATGTTGGCGTTTCTTCAGCATAATGTGGCTCACTTGGGAATTGTCACAGGG
AAATGTTTATCAGAAAATGCGACCCAATATCTCAGGCCCTGGCTCAGTAGAACTATTTTGGGGACAGGAGTCCTAGCATC
TATTTCAACAGCAGTTGCCGAAATTTTGGGTGGAACGATAGCTTTGCAAATGCTTTTTAAATTGCCGATTGTAATAGGTG
CAATTTTAACGGCTGGCTTGGTTATCTGGTTTTTATTCAGCAATTCTTATCCAAAGATTGAAAAAGTAATTATTGGTTTT
GTAAGTTTGATTGGGATTGCACTTTTGCTAGAGATTTTTATTATTCCTCATATTAACTGGGGACAGGCTGCTAAAGGAAT
GGTCATTCCTTTTGTTGATGCAAAATCTATGCCTATTATTATGTCAGCTTTAGGGGCTGTAGTTATGCCTCACAATCTAT
TTTTGCACTCGGAAGTCATTCAAAGTCGTCAGTGGAATTTAAAAGACGAAGCCGTAATGGAAAGACAATTACGTTTTGAA
TTCTTTGATACAATTTTTTCAATGTTTTTAGGTTGGGTCATTAATTCTGCGATTATTATCATTGCTGCCGCTTTATTTTT
CCCACGTATCGTCACCGAAATTAGTCAGGCTCAAGAAATGCTTGTTCCTCTGCTTGGTCCAGTAGCTGCTATTCTCTTTG
CCATTGCCTTTCTTTTTGCAGGAGTTGCTTCGTCAGTCACGGCCGGAATGGCAGGCGGGTCAATTTTTGCAGGAATCTTT
GCAGAACCTTATGATGCCCAAGATCCTCACAGTAAGTTAGGTGTTTTAATTACAATTATTGGTGCAACTCTTGCAATTTG
TGGATTGAGTTTTGTAACGTCATCATTCAATATTTTAATTTATTCACAAGTTTTCCTGAGTATTCAATTACCAATTACCA
TCTTTTTACAAATTTATTTGACAAGTTCTAAAAAAGTGATGGGGAAATATAAGAACGTTTGGTTCACTAAGTGGCTTTTA
TTGGCAACGGGGATTTTTGTAACCCTACTCAATATCGTATTAATCGTCGAAACTTTTAAATAA

Upstream 100 bases:

>100_bases
TATTTTTAATGACCGTCAGTAAAATTTACTGACGGTTTTTTATTTTGTAAGGTTGAACTCTCAAAAGCTCCATGCTATAA
TTGTCCAAAAGGAAGTGGAA

Downstream 100 bases:

>100_bases
TTCTAAAAAATTTGCTATAATAGTTTTGTAAGAAGATTAAAAAATGAGGAGAAAATGATGCAAGCAAAATTAGTTAATAA
AGTAGTCATCAAACGTAACG

Product: putative Mn and Fe transporters

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKKIKMRRFLQDKRHPALDFLKYVGPGLIVAVGFIDPGNWAANLAAGSQFGYKLLWVITLSTIMLAFLQHNVAHLGIVTG
KCLSENATQYLRPWLSRTILGTGVLASISTAVAEILGGTIALQMLFKLPIVIGAILTAGLVIWFLFSNSYPKIEKVIIGF
VSLIGIALLLEIFIIPHINWGQAAKGMVIPFVDAKSMPIIMSALGAVVMPHNLFLHSEVIQSRQWNLKDEAVMERQLRFE
FFDTIFSMFLGWVINSAIIIIAAALFFPRIVTEISQAQEMLVPLLGPVAAILFAIAFLFAGVASSVTAGMAGGSIFAGIF
AEPYDAQDPHSKLGVLITIIGATLAICGLSFVTSSFNILIYSQVFLSIQLPITIFLQIYLTSSKKVMGKYKNVWFTKWLL
LATGIFVTLLNIVLIVETFK

Sequences:

>Translated_420_residues
MKKIKMRRFLQDKRHPALDFLKYVGPGLIVAVGFIDPGNWAANLAAGSQFGYKLLWVITLSTIMLAFLQHNVAHLGIVTG
KCLSENATQYLRPWLSRTILGTGVLASISTAVAEILGGTIALQMLFKLPIVIGAILTAGLVIWFLFSNSYPKIEKVIIGF
VSLIGIALLLEIFIIPHINWGQAAKGMVIPFVDAKSMPIIMSALGAVVMPHNLFLHSEVIQSRQWNLKDEAVMERQLRFE
FFDTIFSMFLGWVINSAIIIIAAALFFPRIVTEISQAQEMLVPLLGPVAAILFAIAFLFAGVASSVTAGMAGGSIFAGIF
AEPYDAQDPHSKLGVLITIIGATLAICGLSFVTSSFNILIYSQVFLSIQLPITIFLQIYLTSSKKVMGKYKNVWFTKWLL
LATGIFVTLLNIVLIVETFK
>Mature_420_residues
MKKIKMRRFLQDKRHPALDFLKYVGPGLIVAVGFIDPGNWAANLAAGSQFGYKLLWVITLSTIMLAFLQHNVAHLGIVTG
KCLSENATQYLRPWLSRTILGTGVLASISTAVAEILGGTIALQMLFKLPIVIGAILTAGLVIWFLFSNSYPKIEKVIIGF
VSLIGIALLLEIFIIPHINWGQAAKGMVIPFVDAKSMPIIMSALGAVVMPHNLFLHSEVIQSRQWNLKDEAVMERQLRFE
FFDTIFSMFLGWVINSAIIIIAAALFFPRIVTEISQAQEMLVPLLGPVAAILFAIAFLFAGVASSVTAGMAGGSIFAGIF
AEPYDAQDPHSKLGVLITIIGATLAICGLSFVTSSFNILIYSQVFLSIQLPITIFLQIYLTSSKKVMGKYKNVWFTKWLL
LATGIFVTLLNIVLIVETFK

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=331, Percent_Identity=26.2839879154079, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI295293175, Length=419, Percent_Identity=27.2076372315036, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI295293173, Length=419, Percent_Identity=27.2076372315036, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI10835169, Length=419, Percent_Identity=27.2076372315036, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI295293178, Length=419, Percent_Identity=27.2076372315036, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI295293167, Length=419, Percent_Identity=27.2076372315036, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI295293171, Length=419, Percent_Identity=27.2076372315036, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI295293169, Length=419, Percent_Identity=27.2076372315036, Blast_Score=112, Evalue=7e-25,
Organism=Escherichia coli, GI1788736, Length=417, Percent_Identity=31.89448441247, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17569473, Length=378, Percent_Identity=28.3068783068783, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI193210616, Length=448, Percent_Identity=27.6785714285714, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71993856, Length=239, Percent_Identity=33.0543933054393, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71999499, Length=263, Percent_Identity=27.7566539923954, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323062, Length=412, Percent_Identity=30.8252427184466, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6324450, Length=431, Percent_Identity=27.6102088167053, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321841, Length=416, Percent_Identity=29.5673076923077, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45553443, Length=430, Percent_Identity=25.1162790697674, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24648607, Length=430, Percent_Identity=25.1162790697674, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281362176, Length=430, Percent_Identity=25.1162790697674, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24648609, Length=430, Percent_Identity=25.1162790697674, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 46043; Mature: 46043

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIKMRRFLQDKRHPALDFLKYVGPGLIVAVGFIDPGNWAANLAAGSQFGYKLLWVITL
CCCHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCCCCCCHHHHHHHHH
STIMLAFLQHNVAHLGIVTGKCLSENATQYLRPWLSRTILGTGVLASISTAVAEILGGTI
HHHHHHHHHHCHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQMLFKLPIVIGAILTAGLVIWFLFSNSYPKIEKVIIGFVSLIGIALLLEIFIIPHINW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GQAAKGMVIPFVDAKSMPIIMSALGAVVMPHNLFLHSEVIQSRQWNLKDEAVMERQLRFE
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FFDTIFSMFLGWVINSAIIIIAAALFFPRIVTEISQAQEMLVPLLGPVAAILFAIAFLFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVASSVTAGMAGGSIFAGIFAEPYDAQDPHSKLGVLITIIGATLAICGLSFVTSSFNILI
HHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEE
YSQVFLSIQLPITIFLQIYLTSSKKVMGKYKNVWFTKWLLLATGIFVTLLNIVLIVETFK
EEHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIKMRRFLQDKRHPALDFLKYVGPGLIVAVGFIDPGNWAANLAAGSQFGYKLLWVITL
CCCHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCCCCCCHHHHHHHHH
STIMLAFLQHNVAHLGIVTGKCLSENATQYLRPWLSRTILGTGVLASISTAVAEILGGTI
HHHHHHHHHHCHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQMLFKLPIVIGAILTAGLVIWFLFSNSYPKIEKVIIGFVSLIGIALLLEIFIIPHINW
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GQAAKGMVIPFVDAKSMPIIMSALGAVVMPHNLFLHSEVIQSRQWNLKDEAVMERQLRFE
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FFDTIFSMFLGWVINSAIIIIAAALFFPRIVTEISQAQEMLVPLLGPVAAILFAIAFLFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVASSVTAGMAGGSIFAGIFAEPYDAQDPHSKLGVLITIIGATLAICGLSFVTSSFNILI
HHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEE
YSQVFLSIQLPITIFLQIYLTSSKKVMGKYKNVWFTKWLLLATGIFVTLLNIVLIVETFK
EEHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA