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The map label for this gene is nagB2 [H]

Identifier: 125624928

GI number: 125624928

Start: 2118632

End: 2119345

Strand: Reverse

Name: nagB2 [H]

Synonym: llmg_2157

Alternate gene names: 125624928

Gene position: 2119345-2118632 (Counterclockwise)

Preceding gene: 125624929

Following gene: 125624927

Centisome position: 83.79

GC content: 37.82

Gene sequence:

>714_bases
ATGAAAAAAATAATCACTAAAGACTATGCAACGATGAGTGAACTTGCTGCAGCGATTGTTCTTGATAAGATGATGCAGCC
AAAAAGAGTGAATCTTTCGCTAACAGCGGGGAATACTCCTCTTGGGATGTATGAAATTCTATTTGATCGACTCCAAAAAA
TGAATTTTGACCGCTCAAATATCCATTATTATAATTTTGATGAAGTGCCTCTTGCTGGAGAACGTTATGGTTTGACAATG
AGTGCTTTAAAAATGGCTTTTTATGACCGAGTGCATATTGATGATGGGAATCTCCATGAGTTAAATTCTCAAAATATTCA
AGTTTTTGATCAAAAAATCTTGCAGGATGGTGGGATTGATTTGATTGTCATGGGGATAGGAGAAGATGGTCATTTTTGTG
CAAATATGCCAGGACATACAAGTTTTGAGCGAGAAGTTTTTGCTGTTCCATTTGAAGAAGGGGATGAAATTTATCGGTCA
ATCAAAGAGCTGACAGATAAAGAACCGGCTTCTCCTTATGTCACTTTTGGGCCACGAACAGTTCTAGCAAGCAAGCAACT
TTTAGTCTTTGCTGATGGAAAAAGTAAAGCAGAAATCATGAAAAAAGTTCTTGAAGGGCCAATAGCGGAGGAAGTTCCTG
CTTCGATTTTGCGAACGCATCCAAATATTACCTTTATTTTAGATGAGGCAGCAGCGGCTTTACTTGAAGATTAA

Upstream 100 bases:

>100_bases
AAAAGCGGATTTCCGCTTTTTTATTTTCAACGAGTAGAGTTGCTTTCAATAGAATACTTAATCCTGTAAAATAGAAGTAA
CGATAAAAAAAGGAGCTTCT

Downstream 100 bases:

>100_bases
AGAATAAATAAAGACAGTTATTGAAGTAGCTGTTTTTATTTATTTTCTTTGAAGTCTATTTATCATGACATAAATGACTT
TAAAATATTCTGAAAGCGTT

Product: putative 6-phosphogluconolactonase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKKIITKDYATMSELAAAIVLDKMMQPKRVNLSLTAGNTPLGMYEILFDRLQKMNFDRSNIHYYNFDEVPLAGERYGLTM
SALKMAFYDRVHIDDGNLHELNSQNIQVFDQKILQDGGIDLIVMGIGEDGHFCANMPGHTSFEREVFAVPFEEGDEIYRS
IKELTDKEPASPYVTFGPRTVLASKQLLVFADGKSKAEIMKKVLEGPIAEEVPASILRTHPNITFILDEAAAALLED

Sequences:

>Translated_237_residues
MKKIITKDYATMSELAAAIVLDKMMQPKRVNLSLTAGNTPLGMYEILFDRLQKMNFDRSNIHYYNFDEVPLAGERYGLTM
SALKMAFYDRVHIDDGNLHELNSQNIQVFDQKILQDGGIDLIVMGIGEDGHFCANMPGHTSFEREVFAVPFEEGDEIYRS
IKELTDKEPASPYVTFGPRTVLASKQLLVFADGKSKAEIMKKVLEGPIAEEVPASILRTHPNITFILDEAAAALLED
>Mature_237_residues
MKKIITKDYATMSELAAAIVLDKMMQPKRVNLSLTAGNTPLGMYEILFDRLQKMNFDRSNIHYYNFDEVPLAGERYGLTM
SALKMAFYDRVHIDDGNLHELNSQNIQVFDQKILQDGGIDLIVMGIGEDGHFCANMPGHTSFEREVFAVPFEEGDEIYRS
IKELTDKEPASPYVTFGPRTVLASKQLLVFADGKSKAEIMKKVLEGPIAEEVPASILRTHPNITFILDEAAAALLED

Specific function: Unknown

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI19923881, Length=246, Percent_Identity=28.8617886178862, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI13027378, Length=253, Percent_Identity=30.0395256916996, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI48994958, Length=229, Percent_Identity=41.4847161572052, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI1789530, Length=228, Percent_Identity=23.2456140350877, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17554876, Length=245, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24581960, Length=248, Percent_Identity=28.6290322580645, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920764, Length=248, Percent_Identity=28.6290322580645, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: NA

Molecular weight: Translated: 26579; Mature: 26579

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIITKDYATMSELAAAIVLDKMMQPKRVNLSLTAGNTPLGMYEILFDRLQKMNFDRSN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
IHYYNFDEVPLAGERYGLTMSALKMAFYDRVHIDDGNLHELNSQNIQVFDQKILQDGGID
CEEECCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCEECCCCCCHHHHHHHHHHCCCCE
LIVMGIGEDGHFCANMPGHTSFEREVFAVPFEEGDEIYRSIKELTDKEPASPYVTFGPRT
EEEEEECCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCEE
VLASKQLLVFADGKSKAEIMKKVLEGPIAEEVPASILRTHPNITFILDEAAAALLED
EECCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHCC
>Mature Secondary Structure
MKKIITKDYATMSELAAAIVLDKMMQPKRVNLSLTAGNTPLGMYEILFDRLQKMNFDRSN
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCC
IHYYNFDEVPLAGERYGLTMSALKMAFYDRVHIDDGNLHELNSQNIQVFDQKILQDGGID
CEEECCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCEECCCCCCHHHHHHHHHHCCCCE
LIVMGIGEDGHFCANMPGHTSFEREVFAVPFEEGDEIYRSIKELTDKEPASPYVTFGPRT
EEEEEECCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCEE
VLASKQLLVFADGKSKAEIMKKVLEGPIAEEVPASILRTHPNITFILDEAAAALLED
EECCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]