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The map label for this gene is trmH [C]

Identifier: 125624835

GI number: 125624835

Start: 2046008

End: 2046736

Strand: Reverse

Name: trmH [C]

Synonym: llmg_2063

Alternate gene names: 125624835

Gene position: 2046736-2046008 (Counterclockwise)

Preceding gene: 125624836

Following gene: 125624834

Centisome position: 80.92

GC content: 37.72

Gene sequence:

>729_bases
ATGGAAAATACAGATTTGATTTACGGATTGCATGCGGTCACGGAAGCACTAAATGGAGACCTTGTCAACAAGCTTTACGT
TCAAGAAGATTTGCGCGGAAAAAATGTTGAAAAAATAAAAGAACTCGCACGAATTAAGAAAGTTAATATATCATGGACTC
CCAAAACAGAATTAAATAAGCTGACAGAAAATGGAGTCCATCAAGGATTTATGGCAAGGGTTTCTGAATTTGCTTACGCT
GATTTAGCAACGTTGCTTCCAGAATTAGCGGAAAAAGCAGAAGCTACAATTTTAATTTTAGATGAGTTGACAGACCCTCA
CAATTTGGGTTCTATTGCGCGTACAGCTGATGCAACTGGTGTGGATGCAATTATTATTCCAAAACATCGAGCAGTTGGTA
TTACACCGACAGCAGTTAAAGCATCAACAGGTGCCTTACAACATGTGCCCGTAGTTCGAGTAACTAATCTGTCACAAACT
TTAGATAAACTAAAAAGTGCTGGATTTTGGATTTTTGGAACAGATATGGATGGTACGGTTTATAACAAATGGAATACTAA
AGGAAAAATTGCTTTGATTATTGGCAACGAGGGACACGGTATTGGTCAGAACCTCAAAAAGCAAGTCGATGAAATGATTA
CAATTCCGATGGTAGGACATGTGCAAAGTCTTAATGCGTCAGTAGCAGCAAGTATTTTGATGTATGAAGTTTTCAGAAAT
CGTCTTTAA

Upstream 100 bases:

>100_bases
ATGCTTTTGTTGATTTACATAATTTTTTTATAGGCTACATAATCAAATAAAATGACGAATTGAGACAGGTTTTTTTCTTT
AAAAATGATATAATGATTTC

Downstream 100 bases:

>100_bases
TATTTACTGATGAAATTAAAGCTTATTTCTAATCACAAATAGGCAAAGAGTGTTCTTTAAACAAGCTGTCAATGAAGCAC
CATTGCTGTCATTTGTAATA

Product: tRNA/rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARIKKVNISWTPKTELNKLTENGVHQGFMARVSEFAYA
DLATLLPELAEKAEATILILDELTDPHNLGSIARTADATGVDAIIIPKHRAVGITPTAVKASTGALQHVPVVRVTNLSQT
LDKLKSAGFWIFGTDMDGTVYNKWNTKGKIALIIGNEGHGIGQNLKKQVDEMITIPMVGHVQSLNASVAASILMYEVFRN
RL

Sequences:

>Translated_242_residues
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARIKKVNISWTPKTELNKLTENGVHQGFMARVSEFAYA
DLATLLPELAEKAEATILILDELTDPHNLGSIARTADATGVDAIIIPKHRAVGITPTAVKASTGALQHVPVVRVTNLSQT
LDKLKSAGFWIFGTDMDGTVYNKWNTKGKIALIIGNEGHGIGQNLKKQVDEMITIPMVGHVQSLNASVAASILMYEVFRN
RL
>Mature_242_residues
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARIKKVNISWTPKTELNKLTENGVHQGFMARVSEFAYA
DLATLLPELAEKAEATILILDELTDPHNLGSIARTADATGVDAIIIPKHRAVGITPTAVKASTGALQHVPVVRVTNLSQT
LDKLKSAGFWIFGTDMDGTVYNKWNTKGKIALIIGNEGHGIGQNLKKQVDEMITIPMVGHVQSLNASVAASILMYEVFRN
RL

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=261, Percent_Identity=24.904214559387, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI110825988, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1790623, Length=245, Percent_Identity=37.1428571428571, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790083, Length=163, Percent_Identity=31.2883435582822, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788935, Length=149, Percent_Identity=27.5167785234899, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555908, Length=257, Percent_Identity=29.5719844357977, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI193204953, Length=143, Percent_Identity=28.6713286713287, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324775, Length=162, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26480; Mature: 26480

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARIKKVNISWTPKTELNK
CCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCHHHHH
LTENGVHQGFMARVSEFAYADLATLLPELAEKAEATILILDELTDPHNLGSIARTADATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCHHHHHCCCCC
VDAIIIPKHRAVGITPTAVKASTGALQHVPVVRVTNLSQTLDKLKSAGFWIFGTDMDGTV
CCEEEECCCCEECCCCCHHCCCCCCHHCCCEEEECCHHHHHHHHHHCCEEEEECCCCCEE
YNKWNTKGKIALIIGNEGHGIGQNLKKQVDEMITIPMVGHVQSLNASVAASILMYEVFRN
EECCCCCCEEEEEECCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHH
RL
CC
>Mature Secondary Structure
MENTDLIYGLHAVTEALNGDLVNKLYVQEDLRGKNVEKIKELARIKKVNISWTPKTELNK
CCCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCHHHHH
LTENGVHQGFMARVSEFAYADLATLLPELAEKAEATILILDELTDPHNLGSIARTADATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCHHHHHCCCCC
VDAIIIPKHRAVGITPTAVKASTGALQHVPVVRVTNLSQTLDKLKSAGFWIFGTDMDGTV
CCEEEECCCCEECCCCCHHCCCCCCHHCCCEEEECCHHHHHHHHHHCCEEEEECCCCCEE
YNKWNTKGKIALIIGNEGHGIGQNLKKQVDEMITIPMVGHVQSLNASVAASILMYEVFRN
EECCCCCCEEEEEECCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHH
RL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA