Click here to switch to the map view.

The map label for this gene is ftsA [H]

Identifier: 125624833

GI number: 125624833

Start: 2043490

End: 2044860

Strand: Reverse

Name: ftsA [H]

Synonym: llmg_2061

Alternate gene names: 125624833

Gene position: 2044860-2043490 (Counterclockwise)

Preceding gene: 125624834

Following gene: 125624832

Centisome position: 80.84

GC content: 40.99

Gene sequence:

>1371_bases
ATGGCCAAAAGTGGACTTTATACAGGCGTAGATATCGGGACAAACACAATAAAGGTGCTTGTTGCTGAATACGTCTCAGG
TGAAATGAATATAATTGGTGTCGGAAACGCAAAATCCGATGGCCTTAAAAATGGAATTATTGTAGATATTGAGAAGGTAG
CACAAGCATTACGAAAAGCTGTAAATGCTGCTGAAGAACGCGCCGGAATCACGATTGATCGAATTAACGTGAGCATTCCA
GCAAATTCCCTCGAAATGGAACCATGCCAAGGTATGGTCCCAATTGTTAGTGATACAAAAGAAATTACAGATAACGATGT
GATTCAAGTCGTTCAAAACGCTTTAATGCGTGGGATTGTTCCTGAAAGAGAAATTATTGCTGTAGAAACAAAAGAGTTTA
CAGTGGATGGCTTTACAGGCATATCAGATCCACGTGGAATGTTTGGTGTTCGACTTGAAATTCGTGGGGTTGTTTACACT
GGCCCTAAAACTCTTGTTCACAATGTTCGTAAAGTTGTTGAACGTGCTGGATTGCTTGTTGACAATATTGTTATTGCTCC
TCTTGCAATGGCACAATATGTGCTCACAGAAGGTGAACGCGAATTTGGAACAATCATGGTTGATTTAGGTGCTGGACAAA
CAACAGTTAGCATTGTAAAAGATCAATCTTTGAAATTTACACATACAAGCCCTGAAGGTGGCGACTATGTGACTAAAGAT
ATTTCAACTGTCTTAAATACCTCTGTTTCGGCAGCGGAAGACTTGAAAGTCAACTATGGTGAAGCAAGTACTGAACGTGC
AAGTCAAGATGAGTATTTCCTTGTTGATGTTGTTGGTAAAGATGAACCAGAACAAATCACAGAATACTACCTCTCACAAA
TCATTGAAGCGCGAATGACTCAAGTCTTTAATCGCGTACGTCAAGATTTGGAACACGGACACACATCAGAAACTCCTGGA
GGACTGATTTTAGTCGGTGGGACAGCTGCTATGCCAGGTGTTGTTGATTTAGCAACAAAAATCTTGGGAATGAATGCTCG
TCTTTACGTTCCTGGAGAAATGGGCTTGCGCAATCCTGCGTTCGCTCAAGTCATTAGTGTAGTTAATTATATCGGAAGTC
GAAGTGATATTGATGTTTTAGTATCACAAGCTTTTTCTGGCGATTATGCCTATACGGCAGCTGAAGAAACTTACGTTGCT
CCTGTTCAAACAATCGCACCACAAGTGACAACAGTAGCCGACGTAGAAAATGATTTCTACACTGAACCTCAATCGCGTCC
AGTTGCAACTCAAAAAGTAACTGAGCCCGAAGAAGAAAAAGAAGGTCTTGTTGACCGTGCCAAAAGTTTCTTTGGCAACC
TCTTTGACTAA

Upstream 100 bases:

>100_bases
ATAATTAATGAGTGTAATTGTATATAAAATTATCTGTACACTTACCTAATTTATTGAAAAAAATATGAATCGTGATGTGT
GAGGGAAAGGAGTCGCTTTT

Downstream 100 bases:

>100_bases
TCTGAAAGTAAAAACGGAGAAATAAAAACATGGAATTTTCATTTGATACAGACTTAACTTCTGGTGCTGTAATTAAAGTT
ATCGGTGTTGGTGGTGGTGG

Product: cell division protein ftsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAKSGLYTGVDIGTNTIKVLVAEYVSGEMNIIGVGNAKSDGLKNGIIVDIEKVAQALRKAVNAAEERAGITIDRINVSIP
ANSLEMEPCQGMVPIVSDTKEITDNDVIQVVQNALMRGIVPEREIIAVETKEFTVDGFTGISDPRGMFGVRLEIRGVVYT
GPKTLVHNVRKVVERAGLLVDNIVIAPLAMAQYVLTEGEREFGTIMVDLGAGQTTVSIVKDQSLKFTHTSPEGGDYVTKD
ISTVLNTSVSAAEDLKVNYGEASTERASQDEYFLVDVVGKDEPEQITEYYLSQIIEARMTQVFNRVRQDLEHGHTSETPG
GLILVGGTAAMPGVVDLATKILGMNARLYVPGEMGLRNPAFAQVISVVNYIGSRSDIDVLVSQAFSGDYAYTAAEETYVA
PVQTIAPQVTTVADVENDFYTEPQSRPVATQKVTEPEEEKEGLVDRAKSFFGNLFD

Sequences:

>Translated_456_residues
MAKSGLYTGVDIGTNTIKVLVAEYVSGEMNIIGVGNAKSDGLKNGIIVDIEKVAQALRKAVNAAEERAGITIDRINVSIP
ANSLEMEPCQGMVPIVSDTKEITDNDVIQVVQNALMRGIVPEREIIAVETKEFTVDGFTGISDPRGMFGVRLEIRGVVYT
GPKTLVHNVRKVVERAGLLVDNIVIAPLAMAQYVLTEGEREFGTIMVDLGAGQTTVSIVKDQSLKFTHTSPEGGDYVTKD
ISTVLNTSVSAAEDLKVNYGEASTERASQDEYFLVDVVGKDEPEQITEYYLSQIIEARMTQVFNRVRQDLEHGHTSETPG
GLILVGGTAAMPGVVDLATKILGMNARLYVPGEMGLRNPAFAQVISVVNYIGSRSDIDVLVSQAFSGDYAYTAAEETYVA
PVQTIAPQVTTVADVENDFYTEPQSRPVATQKVTEPEEEKEGLVDRAKSFFGNLFD
>Mature_455_residues
AKSGLYTGVDIGTNTIKVLVAEYVSGEMNIIGVGNAKSDGLKNGIIVDIEKVAQALRKAVNAAEERAGITIDRINVSIPA
NSLEMEPCQGMVPIVSDTKEITDNDVIQVVQNALMRGIVPEREIIAVETKEFTVDGFTGISDPRGMFGVRLEIRGVVYTG
PKTLVHNVRKVVERAGLLVDNIVIAPLAMAQYVLTEGEREFGTIMVDLGAGQTTVSIVKDQSLKFTHTSPEGGDYVTKDI
STVLNTSVSAAEDLKVNYGEASTERASQDEYFLVDVVGKDEPEQITEYYLSQIIEARMTQVFNRVRQDLEHGHTSETPGG
LILVGGTAAMPGVVDLATKILGMNARLYVPGEMGLRNPAFAQVISVVNYIGSRSDIDVLVSQAFSGDYAYTAAEETYVAP
VQTIAPQVTTVADVENDFYTEPQSRPVATQKVTEPEEEKEGLVDRAKSFFGNLFD

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=387, Percent_Identity=30.749354005168, Blast_Score=180, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494
- InterPro:   IPR021873 [H]

Pfam domain/function: PF11983 DUF3484; PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 49338; Mature: 49207

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSGLYTGVDIGTNTIKVLVAEYVSGEMNIIGVGNAKSDGLKNGIIVDIEKVAQALRKA
CCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHH
VNAAEERAGITIDRINVSIPANSLEMEPCQGMVPIVSDTKEITDNDVIQVVQNALMRGIV
HHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCC
PEREIIAVETKEFTVDGFTGISDPRGMFGVRLEIRGVVYTGPKTLVHNVRKVVERAGLLV
CCCEEEEEECCEEEECCCCCCCCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHCCCHH
DNIVIAPLAMAQYVLTEGEREFGTIMVDLGAGQTTVSIVKDQSLKFTHTSPEGGDYVTKD
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCEEEEECCCCCCCHHHHH
ISTVLNTSVSAAEDLKVNYGEASTERASQDEYFLVDVVGKDEPEQITEYYLSQIIEARMT
HHHHHHCCCCCHHCCEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
QVFNRVRQDLEHGHTSETPGGLILVGGTAAMPGVVDLATKILGMNARLYVPGEMGLRNPA
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHH
FAQVISVVNYIGSRSDIDVLVSQAFSGDYAYTAAEETYVAPVQTIAPQVTTVADVENDFY
HHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCEECCHHHHCCCCEEEEECCCCCC
TEPQSRPVATQKVTEPEEEKEGLVDRAKSFFGNLFD
CCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKSGLYTGVDIGTNTIKVLVAEYVSGEMNIIGVGNAKSDGLKNGIIVDIEKVAQALRKA
CCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHH
VNAAEERAGITIDRINVSIPANSLEMEPCQGMVPIVSDTKEITDNDVIQVVQNALMRGIV
HHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCC
PEREIIAVETKEFTVDGFTGISDPRGMFGVRLEIRGVVYTGPKTLVHNVRKVVERAGLLV
CCCEEEEEECCEEEECCCCCCCCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHCCCHH
DNIVIAPLAMAQYVLTEGEREFGTIMVDLGAGQTTVSIVKDQSLKFTHTSPEGGDYVTKD
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCEEEEECCCCCCCHHHHH
ISTVLNTSVSAAEDLKVNYGEASTERASQDEYFLVDVVGKDEPEQITEYYLSQIIEARMT
HHHHHHCCCCCHHCCEEECCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
QVFNRVRQDLEHGHTSETPGGLILVGGTAAMPGVVDLATKILGMNARLYVPGEMGLRNPA
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHH
FAQVISVVNYIGSRSDIDVLVSQAFSGDYAYTAAEETYVAPVQTIAPQVTTVADVENDFY
HHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCEECCHHHHCCCCEEEEECCCCCC
TEPQSRPVATQKVTEPEEEKEGLVDRAKSFFGNLFD
CCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9287029; 12663927 [H]