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The map label for this gene is infC [H]

Identifier: 125624804

GI number: 125624804

Start: 2016189

End: 2016839

Strand: Reverse

Name: infC [H]

Synonym: llmg_2031

Alternate gene names: 125624804

Gene position: 2016839-2016189 (Counterclockwise)

Preceding gene: 125624807

Following gene: 125624803

Centisome position: 79.73

GC content: 38.25

Gene sequence:

>651_bases
ATGGAATTATTCAAAAACGAATGTTTTCATGAGCGGGGCGAGATTGTCGTTCCGCTTTTGTTTTTCTTTAAAAAAGAAGT
TGAGCTAAATTTTAGCCAACTTTCACATCATATTAGAAGGAGAACGAACATAGCTAAACAAGACAATAGAAAACCTATGA
TGAACGGTGCAATCCGTGCTCGTGAGGTTCGTCTCATTGGCGCTGAGGGTGAACAATTAGGTGTCACACCAACGTCTGAG
GCGTTAATGCAAGCTGAAAATCTTAACATGGACTTGGTTTTAATTTCAAATCAAGAACCACCTGTTGCTAAAATCATGGA
TTATACAAAATTCATGTTTGAGCAAAAGAAAAAACAAAAAGAAGCAAAGAAAAAACAAGCAGTTGTTTCTGTAAAAGAAG
TCCGTTTGTCACCAGTTATTGACCAAAACGACTTTGATACAAAGCTTCGCCAAGCCATCAAGTTCCTTGAAAAAGGCGAT
AAAGTTAAGGTTTCAATCCGATTTAAAGGTCGGATGATTACTCACCAAGATGTGGGTCGTCAAGTAATGGACAAGTTCGC
GGAAGCAACAAAAGAAGTTGCTGTCGTTGAACAAAGAGCCAAAATGGATGGGCGTCAAATGTTCTTGCAACTTGCTCCTA
TAAAAAAATAG

Upstream 100 bases:

>100_bases
ATTAGGGCTTGACAAGTTCTAAAATAATTGATAGAATAATAGAGTTGAAAAGCAGAAGCACCCGCTTCTCGCCTTAGAGG
TTATAGCCCTGGGCAAACAA

Downstream 100 bases:

>100_bases
GTCTGTACAAGATAAGCTCGTCTCGAAAGGGTAACCTTTCAAGCCTTTATTCTTTAGACTAGTGCTTTAAGAATAAAGAA
AGCAGAATTCATCTTCTGCT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MELFKNECFHERGEIVVPLLFFFKKEVELNFSQLSHHIRRRTNIAKQDNRKPMMNGAIRAREVRLIGAEGEQLGVTPTSE
ALMQAENLNMDLVLISNQEPPVAKIMDYTKFMFEQKKKQKEAKKKQAVVSVKEVRLSPVIDQNDFDTKLRQAIKFLEKGD
KVKVSIRFKGRMITHQDVGRQVMDKFAEATKEVAVVEQRAKMDGRQMFLQLAPIKK

Sequences:

>Translated_216_residues
MELFKNECFHERGEIVVPLLFFFKKEVELNFSQLSHHIRRRTNIAKQDNRKPMMNGAIRAREVRLIGAEGEQLGVTPTSE
ALMQAENLNMDLVLISNQEPPVAKIMDYTKFMFEQKKKQKEAKKKQAVVSVKEVRLSPVIDQNDFDTKLRQAIKFLEKGD
KVKVSIRFKGRMITHQDVGRQVMDKFAEATKEVAVVEQRAKMDGRQMFLQLAPIKK
>Mature_216_residues
MELFKNECFHERGEIVVPLLFFFKKEVELNFSQLSHHIRRRTNIAKQDNRKPMMNGAIRAREVRLIGAEGEQLGVTPTSE
ALMQAENLNMDLVLISNQEPPVAKIMDYTKFMFEQKKKQKEAKKKQAVVSVKEVRLSPVIDQNDFDTKLRQAIKFLEKGD
KVKVSIRFKGRMITHQDVGRQVMDKFAEATKEVAVVEQRAKMDGRQMFLQLAPIKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=51.1627906976744, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 25047; Mature: 25047

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELFKNECFHERGEIVVPLLFFFKKEVELNFSQLSHHIRRRTNIAKQDNRKPMMNGAIRA
CCCHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHCCCCCCHHHCCCEE
REVRLIGAEGEQLGVTPTSEALMQAENLNMDLVLISNQEPPVAKIMDYTKFMFEQKKKQK
EEEEEECCCCCEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
EAKKKQAVVSVKEVRLSPVIDQNDFDTKLRQAIKFLEKGDKVKVSIRFKGRMITHQDVGR
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCEEECHHHHHH
QVMDKFAEATKEVAVVEQRAKMDGRQMFLQLAPIKK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure
MELFKNECFHERGEIVVPLLFFFKKEVELNFSQLSHHIRRRTNIAKQDNRKPMMNGAIRA
CCCHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHCCCCCCHHHCCCEE
REVRLIGAEGEQLGVTPTSEALMQAENLNMDLVLISNQEPPVAKIMDYTKFMFEQKKKQK
EEEEEECCCCCEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
EAKKKQAVVSVKEVRLSPVIDQNDFDTKLRQAIKFLEKGDKVKVSIRFKGRMITHQDVGR
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCEEECHHHHHH
QVMDKFAEATKEVAVVEQRAKMDGRQMFLQLAPIKK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]