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The map label for this gene is asnC [H]

Identifier: 125624792

GI number: 125624792

Start: 2002619

End: 2003962

Strand: Reverse

Name: asnC [H]

Synonym: llmg_2017

Alternate gene names: 125624792

Gene position: 2003962-2002619 (Counterclockwise)

Preceding gene: 125624793

Following gene: 125624790

Centisome position: 79.22

GC content: 37.72

Gene sequence:

>1344_bases
ATGAAAGACTTAATATCAATCATTGATGTAAAAGACCACGTTGGTGAAACAGTAAAAATCGGCGCTTGGGTCGCTGACAA
ATCAGGTAAAGGGAAACTTCAATTTCTTCAACTTCGCGATGGAACAGCGTTTTTTCAAGCTGTTGTTTTCAAACCAAATA
TGATTGAAAAATTTGGTGAAGAAGAAGGAACAGCTAAATTCGATGAAATCAAACATTTATCACAAGAAACTTCAGTTTAT
GTGACTGGTGTGGTCAAAGAAGATTCACGTTCAAAATTTGGTTATGAACTTGATGTGACAGAGTTGGAAGTGATTGGTCA
CTCACACGATTATCCAATTACACCAAAAGAACATGGAGTTGAATTCCTCCTTGATAACCGTCATTTATGGTTGCGCTCAA
AACGTCAAATGGCAATGATGCAAGTGCGTAATGCAATTATCTATGCAAGCTATGATTTCTTTGCGAAAAATGGCTTTATT
AAGTTTGATAGCCCAATTCTTTCAGGAAATGCTGCAGAAAACACAACAGAACTTTTTGAAACAGATTATTTTGGTAATCC
TGCTTTCTTGTCACAATCAGGACAACTTTATCTTGAAGCTGGAGCAATGGCTCTTGGACGTGTTTTCGACTTTGGACCAG
TATTCCGTGCTGAAAAATCAAAAACTCGTCGTCATTTGACAGAATTTTGGATGATGGATGCAGAATATCCATTTGTTACT
CATGATGAATCTTTGGATATTCAAGAAGCTTATGTAAAAGCTTTGATTCAAGGCGTTTTGGATAATGCGGCTTATGCTCT
TGAAACACTTGAACGTGATACAAGCATGTTGCAAAAGTATATTGATACACCTTTCAAACGTGTTTCTTATGATGATGCTA
TTGATTTGTTGCAAGCACACGAAAATGATGAAGATACAGATTATGAGCATGTAGAACATGGGGATGACTTCGGTTCGCCT
CATGAAACATGGATTTCAAATTACTATGGTGTTCCAACATTTATCGTCAACTATCCTGCAAGTTTCAAAGCTTTCTACAT
GAAACCAGTCCCTGGTAACCCAGAACGCGTTTTGTGTGCTGACCTTTTGGCTCCAGAAGGCTATGGTGAAATTATTGGTG
GTTCAGAACGTGAAACAGATTATGATTTGTTACTTAAGAAAATTGCTGATTTCGGTTTAGATCCTAAAGATTATGATTGG
TATTTAGAACTTCGCAAATTTGGTTCAGTTCCTCATGCTGGTTTCGGACTTGGTCTGGAACGTATGGTCACTTTTGTGGC
TGGAACAGAACACATTCGTGAAGCAATTCCATTCCCACGTATGATTAACCGTATCCAACCTTAA

Upstream 100 bases:

>100_bases
AATTCAAAGAAGATTTAAAAACCTTAAAAGAAATCTGGCTTGAAAAGTCATAAAAGTATGATTTAAAAAATATAAAATAA
AAATTTAGAAGGATTTATTT

Downstream 100 bases:

>100_bases
AAAATAAAAGCCTCTAAATTAGAGGCTTTTTTATTACTTATTATTCATTATTCAGAAGCTGAGGATGAGCTTACTGCATC
AATATCATTTTGTGTGATTA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKDLISIIDVKDHVGETVKIGAWVADKSGKGKLQFLQLRDGTAFFQAVVFKPNMIEKFGEEEGTAKFDEIKHLSQETSVY
VTGVVKEDSRSKFGYELDVTELEVIGHSHDYPITPKEHGVEFLLDNRHLWLRSKRQMAMMQVRNAIIYASYDFFAKNGFI
KFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFVT
HDESLDIQEAYVKALIQGVLDNAAYALETLERDTSMLQKYIDTPFKRVSYDDAIDLLQAHENDEDTDYEHVEHGDDFGSP
HETWISNYYGVPTFIVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSERETDYDLLLKKIADFGLDPKDYDW
YLELRKFGSVPHAGFGLGLERMVTFVAGTEHIREAIPFPRMINRIQP

Sequences:

>Translated_447_residues
MKDLISIIDVKDHVGETVKIGAWVADKSGKGKLQFLQLRDGTAFFQAVVFKPNMIEKFGEEEGTAKFDEIKHLSQETSVY
VTGVVKEDSRSKFGYELDVTELEVIGHSHDYPITPKEHGVEFLLDNRHLWLRSKRQMAMMQVRNAIIYASYDFFAKNGFI
KFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFVT
HDESLDIQEAYVKALIQGVLDNAAYALETLERDTSMLQKYIDTPFKRVSYDDAIDLLQAHENDEDTDYEHVEHGDDFGSP
HETWISNYYGVPTFIVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSERETDYDLLLKKIADFGLDPKDYDW
YLELRKFGSVPHAGFGLGLERMVTFVAGTEHIREAIPFPRMINRIQP
>Mature_447_residues
MKDLISIIDVKDHVGETVKIGAWVADKSGKGKLQFLQLRDGTAFFQAVVFKPNMIEKFGEEEGTAKFDEIKHLSQETSVY
VTGVVKEDSRSKFGYELDVTELEVIGHSHDYPITPKEHGVEFLLDNRHLWLRSKRQMAMMQVRNAIIYASYDFFAKNGFI
KFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFVT
HDESLDIQEAYVKALIQGVLDNAAYALETLERDTSMLQKYIDTPFKRVSYDDAIDLLQAHENDEDTDYEHVEHGDDFGSP
HETWISNYYGVPTFIVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSERETDYDLLLKKIADFGLDPKDYDW
YLELRKFGSVPHAGFGLGLERMVTFVAGTEHIREAIPFPRMINRIQP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=456, Percent_Identity=33.1140350877193, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI4758762, Length=453, Percent_Identity=33.5540838852097, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI45439306, Length=471, Percent_Identity=28.0254777070064, Blast_Score=153, Evalue=3e-37,
Organism=Escherichia coli, GI1787161, Length=474, Percent_Identity=33.7552742616034, Blast_Score=258, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI71984122, Length=451, Percent_Identity=37.4722838137472, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17556372, Length=379, Percent_Identity=30.3430079155673, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17551876, Length=490, Percent_Identity=27.7551020408163, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6321807, Length=451, Percent_Identity=32.1507760532151, Blast_Score=224, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6319872, Length=465, Percent_Identity=31.6129032258064, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6323011, Length=450, Percent_Identity=28, Blast_Score=139, Evalue=8e-34,
Organism=Drosophila melanogaster, GI19921528, Length=438, Percent_Identity=34.703196347032, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI19922416, Length=471, Percent_Identity=31.2101910828025, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI17136276, Length=475, Percent_Identity=26.9473684210526, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 50932; Mature: 50932

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLISIIDVKDHVGETVKIGAWVADKSGKGKLQFLQLRDGTAFFQAVVFKPNMIEKFGE
CCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHCC
EEGTAKFDEIKHLSQETSVYVTGVVKEDSRSKFGYELDVTELEVIGHSHDYPITPKEHGV
CCCCCHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEECCCEEEEECCCCCCCCCCHHCCC
EFLLDNRHLWLRSKRQMAMMQVRNAIIYASYDFFAKNGFIKFDSPILSGNAAENTTELFE
EEEECCCEEEHHHHHHHHHHHHHHEEEEEEEHHHHCCCEEEECCCEECCCCCCCHHHHHH
TDYFGNPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFVT
HCCCCCCCEECCCCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
HDESLDIQEAYVKALIQGVLDNAAYALETLERDTSMLQKYIDTPFKRVSYDDAIDLLQAH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHC
ENDEDTDYEHVEHGDDFGSPHETWISNYYGVPTFIVNYPASFKAFYMKPVPGNPERVLCA
CCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEH
DLLAPEGYGEIIGGSERETDYDLLLKKIADFGLDPKDYDWYLELRKFGSVPHAGFGLGLE
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHH
RMVTFVAGTEHIREAIPFPRMINRIQP
HHHHHHHCHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MKDLISIIDVKDHVGETVKIGAWVADKSGKGKLQFLQLRDGTAFFQAVVFKPNMIEKFGE
CCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHCC
EEGTAKFDEIKHLSQETSVYVTGVVKEDSRSKFGYELDVTELEVIGHSHDYPITPKEHGV
CCCCCHHHHHHHHHHCCEEEEEEEEECCCCCCCCEEECCCEEEEECCCCCCCCCCHHCCC
EFLLDNRHLWLRSKRQMAMMQVRNAIIYASYDFFAKNGFIKFDSPILSGNAAENTTELFE
EEEECCCEEEHHHHHHHHHHHHHHEEEEEEEHHHHCCCEEEECCCEECCCCCCCHHHHHH
TDYFGNPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFVT
HCCCCCCCEECCCCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
HDESLDIQEAYVKALIQGVLDNAAYALETLERDTSMLQKYIDTPFKRVSYDDAIDLLQAH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHC
ENDEDTDYEHVEHGDDFGSPHETWISNYYGVPTFIVNYPASFKAFYMKPVPGNPERVLCA
CCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEH
DLLAPEGYGEIIGGSERETDYDLLLKKIADFGLDPKDYDWYLELRKFGSVPHAGFGLGLE
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHH
RMVTFVAGTEHIREAIPFPRMINRIQP
HHHHHHHCHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]