Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 125624750

GI number: 125624750

Start: 1953004

End: 1954221

Strand: Reverse

Name: csd [H]

Synonym: llmg_1972

Alternate gene names: 125624750

Gene position: 1954221-1953004 (Counterclockwise)

Preceding gene: 125624751

Following gene: 125624749

Centisome position: 77.26

GC content: 38.01

Gene sequence:

>1218_bases
ATGCTTGAAGGCATCAAAAATGAATTTCCAGTTCTGAATCAAATTGTTAATGATGAACCTTTGGTTTATTTGGATAATGC
AGCAACCACTCAAAAACCTTTGAGCGTTTTGTCAGCGATAAAGGATTATTATGAAAATGATAACGCCAATGTCCATCGTG
GTGTTCATACTTTGGCAGAACGAGCAACTGAAAAATATGAAGCAGCGCGTGAAAAAGTCCGTGCCTTTATCAATGCTAAA
TCAACAAAAGAAGTCTTATTTACCAGAGGGACAACCACCTCAATTAATTGGGTGGCTCAATTTGCTGGACAAATCTTGAA
AGCAGATGATGAGATTGTCATTTCCATTATGGAACATCATTCTAACATCGTTCCTTGGCAAGAAGTAGCTAAGAAAACAG
GGGCAATATTAAAATTTGTTTATCTCAAAGAGGGCGAATTGGATATGGAAGATTTGCGTCAAAAAGTCACAGCGCAAACG
AAATTCGTGTCAATTGCTCATGTTTCTAATGTCTTAGGGACGATTAATCCGATAGAGGAAATTTCAAAAATTGCTCATGA
ACAGGGTGCCTATCTGGTCGTTGATGGTGCGCAGTCTACCCCTCATATGGCGATTGACCTTCAAAAAATGGATGTCGATT
TCTTTGCTTTTTCAGGTCATAAAATGATGGGACCCACAGGGATAGGTGTTCTTTATGGCAAAGAAGAATTACTTAATCAA
TTTGAGCCCATCGAATTCGGTGGGGAAATGATTGATTTTGTTTATGAAAGTCATTCAACCTGGACAGAACTTCCTTGGAA
ATTTGAAGCAGGAACACCAAATATTGCGGGTGCTATTGCTTTAGGAGCAGCTATTGATTATATTCAAGAGCTTGGAATTG
ACCAAATTCATCAACATGAAGACGAATTGATAGATTATGTGATGCCAAAACTTCAGAATATTGAAGGCTTAACAATTTAT
GGACCAAAAGATAACAAAAAACGTAGTGGAGTTATTGCTTTTAATATTGAAGGCCTTCATCCGCATGATGTCGCTACGGC
ATTGGATATGGAAGGGGTTGCTGTAAGAGCTGGTCATCACTGTGCTCAACCATTATTGAATTATCTTGATACTCCGGCAA
CGGCTAGAGCAAGCTTTTATATCTATAATACCAAAGCAGACTGTGATAAATTGGTTGAGGCACTTCAAAAAACAAAGGAG
TTTTTCAAACTTGATTAA

Upstream 100 bases:

>100_bases
TTGTTATTCGTGGATTCCTTGGCTCAGTCGTCAGTGAAATTCCTGTCAAATCAGTTCAAGCAGAATTTATTGAAACTATT
GAAAGAAAGCTGGGCATGTA

Downstream 100 bases:

>100_bases
TATGCTTAATTGGGTCGCCTCCCTCCCACTTTGGTTGGCAACCACTTTCTTATTCGTTGTTGTTTTCTTTAGAGCTCAAT
GTACCTTTTGGCTAGGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MLEGIKNEFPVLNQIVNDEPLVYLDNAATTQKPLSVLSAIKDYYENDNANVHRGVHTLAERATEKYEAAREKVRAFINAK
STKEVLFTRGTTTSINWVAQFAGQILKADDEIVISIMEHHSNIVPWQEVAKKTGAILKFVYLKEGELDMEDLRQKVTAQT
KFVSIAHVSNVLGTINPIEEISKIAHEQGAYLVVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
FEPIEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHEDELIDYVMPKLQNIEGLTIY
GPKDNKKRSGVIAFNIEGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLDTPATARASFYIYNTKADCDKLVEALQKTKE
FFKLD

Sequences:

>Translated_405_residues
MLEGIKNEFPVLNQIVNDEPLVYLDNAATTQKPLSVLSAIKDYYENDNANVHRGVHTLAERATEKYEAAREKVRAFINAK
STKEVLFTRGTTTSINWVAQFAGQILKADDEIVISIMEHHSNIVPWQEVAKKTGAILKFVYLKEGELDMEDLRQKVTAQT
KFVSIAHVSNVLGTINPIEEISKIAHEQGAYLVVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
FEPIEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHEDELIDYVMPKLQNIEGLTIY
GPKDNKKRSGVIAFNIEGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLDTPATARASFYIYNTKADCDKLVEALQKTKE
FFKLD
>Mature_405_residues
MLEGIKNEFPVLNQIVNDEPLVYLDNAATTQKPLSVLSAIKDYYENDNANVHRGVHTLAERATEKYEAAREKVRAFINAK
STKEVLFTRGTTTSINWVAQFAGQILKADDEIVISIMEHHSNIVPWQEVAKKTGAILKFVYLKEGELDMEDLRQKVTAQT
KFVSIAHVSNVLGTINPIEEISKIAHEQGAYLVVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
FEPIEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHEDELIDYVMPKLQNIEGLTIY
GPKDNKKRSGVIAFNIEGLHPHDVATALDMEGVAVRAGHHCAQPLLNYLDTPATARASFYIYNTKADCDKLVEALQKTKE
FFKLD

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=299, Percent_Identity=26.4214046822742, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI156713448, Length=328, Percent_Identity=25.609756097561, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787970, Length=401, Percent_Identity=48.1296758104738, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1789175, Length=400, Percent_Identity=42, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI48994898, Length=230, Percent_Identity=28.695652173913, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193211090, Length=367, Percent_Identity=27.7929155313352, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI25143064, Length=234, Percent_Identity=34.1880341880342, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319831, Length=397, Percent_Identity=25.6926952141058, Blast_Score=116, Evalue=7e-27,
Organism=Drosophila melanogaster, GI20129463, Length=242, Percent_Identity=30.5785123966942, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45194; Mature: 45194

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEGIKNEFPVLNQIVNDEPLVYLDNAATTQKPLSVLSAIKDYYENDNANVHRGVHTLAE
CCCCCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RATEKYEAAREKVRAFINAKSTKEVLFTRGTTTSINWVAQFAGQILKADDEIVISIMEHH
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHC
SNIVPWQEVAKKTGAILKFVYLKEGELDMEDLRQKVTAQTKFVSIAHVSNVLGTINPIEE
CCCCCHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ISKIAHEQGAYLVVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
HHHHHHHCCCEEEEECCCCCCCEEEEEEECCEEEEEECCCCEECCCCCEEEECHHHHHHC
FEPIEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHE
CCCCHHCHHHHHHHHHCCCCHHCCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
DELIDYVMPKLQNIEGLTIYGPKDNKKRSGVIAFNIEGLHPHDVATALDMEGVAVRAGHH
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEECCHH
CAQPLLNYLDTPATARASFYIYNTKADCDKLVEALQKTKEFFKLD
HHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEGIKNEFPVLNQIVNDEPLVYLDNAATTQKPLSVLSAIKDYYENDNANVHRGVHTLAE
CCCCCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RATEKYEAAREKVRAFINAKSTKEVLFTRGTTTSINWVAQFAGQILKADDEIVISIMEHH
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHC
SNIVPWQEVAKKTGAILKFVYLKEGELDMEDLRQKVTAQTKFVSIAHVSNVLGTINPIEE
CCCCCHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ISKIAHEQGAYLVVDGAQSTPHMAIDLQKMDVDFFAFSGHKMMGPTGIGVLYGKEELLNQ
HHHHHHHCCCEEEEECCCCCCCEEEEEEECCEEEEEECCCCEECCCCCEEEECHHHHHHC
FEPIEFGGEMIDFVYESHSTWTELPWKFEAGTPNIAGAIALGAAIDYIQELGIDQIHQHE
CCCCHHCHHHHHHHHHCCCCHHCCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
DELIDYVMPKLQNIEGLTIYGPKDNKKRSGVIAFNIEGLHPHDVATALDMEGVAVRAGHH
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEEECCHH
CAQPLLNYLDTPATARASFYIYNTKADCDKLVEALQKTKEFFKLD
HHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]