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The map label for this gene is tenA [H]

Identifier: 125624739

GI number: 125624739

Start: 1943058

End: 1943714

Strand: Reverse

Name: tenA [H]

Synonym: llmg_1961

Alternate gene names: 125624739

Gene position: 1943714-1943058 (Counterclockwise)

Preceding gene: 125624740

Following gene: 125624738

Centisome position: 76.84

GC content: 35.92

Gene sequence:

>657_bases
ATGTTATTTACTGAATTAGCAAGAGAAAAGTCAGCAAAATATTGGGAAATGAGTTTTGAACATCCTTTTATCGAAGGTTT
AGTGACGGGGAACTTATCTTCTGATGTTTTCCGATATTACTTACTTCAAGATCGCTATTATTTAGAGCACTTTAGTAAGC
TCTATCTTTATATTGCGGAAAAAACTGAGGATAAAATGATTCGAGAACATTTAAAATTAAATGCAGAAGAATTAAAAGAA
GGTGAAATATTCATTCGAGAAGGTTTTTTTAGGGACTTAGACATTACCGAGCAAGAAATTTCAGAAACCGCTATTGCTCC
AACTGCTTATCATTATGTTTCTCATATGTATCGTCAGCTCGTTGATGGTACGGTTAATACAGCTATTGCTGGCATGTTGC
CTTGCGCTTGGCTTTATCATGAGATTGGACTTCGTTTGATTGATAGGGGTTCTTCTAACGCCTTATACCAACGATGGATT
GAAACATACGCGAGTGAAGAGGCTGCGGCACAAATCGAAAAAGAGTGTGCCATTATCAATCAACTTTATCAAGAAAGTAA
TGAGTCAGAACGTGAAAAAATGCTTGAAGCTTTTGTGATTAGCAGTAAGATGGAATACGAATTTTGGGAAATGTCGATGA
ACTTAGAAAAATGGTGA

Upstream 100 bases:

>100_bases
AGATCTTTGCACATTGTTCCAGTTAAAAAATGGTATAATGTGCAAAACTGTTATATATAAAATACTTTTTAACTTATGGA
AAATTTTAAGGAAAATGAAA

Downstream 100 bases:

>100_bases
TTTTTCGGGAATAAGTGAGAAATATCGATATGACTTATAATGTAAAAAAAAACATTAATTTTATTTCAGTTATTTCTTGC
AAACGGATACACAAAATGTT

Product: transcriptional activator TenA

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLFTELAREKSAKYWEMSFEHPFIEGLVTGNLSSDVFRYYLLQDRYYLEHFSKLYLYIAEKTEDKMIREHLKLNAEELKE
GEIFIREGFFRDLDITEQEISETAIAPTAYHYVSHMYRQLVDGTVNTAIAGMLPCAWLYHEIGLRLIDRGSSNALYQRWI
ETYASEEAAAQIEKECAIINQLYQESNESEREKMLEAFVISSKMEYEFWEMSMNLEKW

Sequences:

>Translated_218_residues
MLFTELAREKSAKYWEMSFEHPFIEGLVTGNLSSDVFRYYLLQDRYYLEHFSKLYLYIAEKTEDKMIREHLKLNAEELKE
GEIFIREGFFRDLDITEQEISETAIAPTAYHYVSHMYRQLVDGTVNTAIAGMLPCAWLYHEIGLRLIDRGSSNALYQRWI
ETYASEEAAAQIEKECAIINQLYQESNESEREKMLEAFVISSKMEYEFWEMSMNLEKW
>Mature_218_residues
MLFTELAREKSAKYWEMSFEHPFIEGLVTGNLSSDVFRYYLLQDRYYLEHFSKLYLYIAEKTEDKMIREHLKLNAEELKE
GEIFIREGFFRDLDITEQEISETAIAPTAYHYVSHMYRQLVDGTVNTAIAGMLPCAWLYHEIGLRLIDRGSSNALYQRWI
ETYASEEAAAQIEKECAIINQLYQESNESEREKMLEAFVISSKMEYEFWEMSMNLEKW

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 25907; Mature: 25907

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFTELAREKSAKYWEMSFEHPFIEGLVTGNLSSDVFRYYLLQDRYYLEHFSKLYLYIAE
CCHHHHHHHHCCCCEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTEDKMIREHLKLNAEELKEGEIFIREGFFRDLDITEQEISETAIAPTAYHYVSHMYRQL
CCHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
VDGTVNTAIAGMLPCAWLYHEIGLRLIDRGSSNALYQRWIETYASEEAAAQIEKECAIIN
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
QLYQESNESEREKMLEAFVISSKMEYEFWEMSMNLEKW
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MLFTELAREKSAKYWEMSFEHPFIEGLVTGNLSSDVFRYYLLQDRYYLEHFSKLYLYIAE
CCHHHHHHHHCCCCEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTEDKMIREHLKLNAEELKEGEIFIREGFFRDLDITEQEISETAIAPTAYHYVSHMYRQL
CCHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
VDGTVNTAIAGMLPCAWLYHEIGLRLIDRGSSNALYQRWIETYASEEAAAQIEKECAIIN
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHH
QLYQESNESEREKMLEAFVISSKMEYEFWEMSMNLEKW
HHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]