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The map label for this gene is tatD [H]

Identifier: 125624670

GI number: 125624670

Start: 1866749

End: 1867522

Strand: Reverse

Name: tatD [H]

Synonym: llmg_1885

Alternate gene names: 125624670

Gene position: 1867522-1866749 (Counterclockwise)

Preceding gene: 125624671

Following gene: 125624669

Centisome position: 73.83

GC content: 36.69

Gene sequence:

>774_bases
ATGGAAATTTTTGATACACATACGCATCTTAATACTATTGAATTTGAAGGACGTGTTAAAGAAGAAATAAGTAAAGCTCA
ATCCTTTGGCGTCACAAAAATAAACAATGTTGGAAGTAATTATCAGTTAAACGATGCTGCGCTTTTATTGGCTGATAAAT
TTGAATCAGCTTATGCAACAATTGGTTGGCATCCTGATGATGCTGCTGAATTTGATACTGCTGCTGAGGAATATTTACTG
ACAAAAGGAAGAAGCAAAAAAGTAATTGCTGTTGGTGAAATTGGTTTGGACTATCATTGGATGGTCTCTCCTAAAGAGGT
TCAGGAACGAGTTTTTAGAAGACAAATTCAAATCTCAAAAGAATTAGGAATTCCTTTTCAAGTTCATACGCGGGATGCTC
TTTCTGATACTTATGAAATTATTAAATCAGAAGGTGTCAGGACTGCTGGTGCGATCATGCATTCATTCTCAGGAACAGCT
GAAGAAGCACTCAAGTTTGTTGAACTTGGCATGAATATTTCATTCTCAGGTGTGGTAACTTTCAAAAAAGCGTTGGATGT
TCAAGAAGCGGCTCGTTTACTTCCGTTGGATAAGATTTTAGTTGAAACCGATGCTCCTTATTTGACACCAACTCCTTATC
GGGGCAAAGAAAACACACCAGGATATACGAAGTATGTTGTTGAAAAAATAGCTGATTTACGCGGTATTTCAATGGAAGAA
GTTGCTGAGGCAACAAACGAAAATGCTTTGAAAATTTTTGACCTGAAAAAGTAG

Upstream 100 bases:

>100_bases
GAATCATGAGGAAGATTAGGGAACATCAATTTTGAAATTCATCTCAAAACTCTTGTTAAAGACTATTTAGGAATAATAAG
GAAGTATAAATAAAAATATA

Downstream 100 bases:

>100_bases
AGTAATTACTTAGTTTTGCTAGGAGCTATTTTTATGAAAATTATTATTATCGGTAGTTCAGGTAGCGGAAAATCGACTTT
AGCAAGAGAAATAGCAAAAA

Product: putative deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MEIFDTHTHLNTIEFEGRVKEEISKAQSFGVTKINNVGSNYQLNDAALLLADKFESAYATIGWHPDDAAEFDTAAEEYLL
TKGRSKKVIAVGEIGLDYHWMVSPKEVQERVFRRQIQISKELGIPFQVHTRDALSDTYEIIKSEGVRTAGAIMHSFSGTA
EEALKFVELGMNISFSGVVTFKKALDVQEAARLLPLDKILVETDAPYLTPTPYRGKENTPGYTKYVVEKIADLRGISMEE
VAEATNENALKIFDLKK

Sequences:

>Translated_257_residues
MEIFDTHTHLNTIEFEGRVKEEISKAQSFGVTKINNVGSNYQLNDAALLLADKFESAYATIGWHPDDAAEFDTAAEEYLL
TKGRSKKVIAVGEIGLDYHWMVSPKEVQERVFRRQIQISKELGIPFQVHTRDALSDTYEIIKSEGVRTAGAIMHSFSGTA
EEALKFVELGMNISFSGVVTFKKALDVQEAARLLPLDKILVETDAPYLTPTPYRGKENTPGYTKYVVEKIADLRGISMEE
VAEATNENALKIFDLKK
>Mature_257_residues
MEIFDTHTHLNTIEFEGRVKEEISKAQSFGVTKINNVGSNYQLNDAALLLADKFESAYATIGWHPDDAAEFDTAAEEYLL
TKGRSKKVIAVGEIGLDYHWMVSPKEVQERVFRRQIQISKELGIPFQVHTRDALSDTYEIIKSEGVRTAGAIMHSFSGTA
EEALKFVELGMNISFSGVVTFKKALDVQEAARLLPLDKILVETDAPYLTPTPYRGKENTPGYTKYVVEKIADLRGISMEE
VAEATNENALKIFDLKK

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=264, Percent_Identity=28.4090909090909, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI225903424, Length=269, Percent_Identity=30.1115241635688, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI225903439, Length=246, Percent_Identity=28.4552845528455, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=27.7153558052434, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=27.7153558052434, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=27.5735294117647, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI226061614, Length=260, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=24.8908296943231, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787342, Length=260, Percent_Identity=36.9230769230769, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=31.3953488372093, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=28.7937743190661, Blast_Score=117, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=29.0780141843972, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=27.5471698113208, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=216, Percent_Identity=30.5555555555556, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=214, Percent_Identity=29.4392523364486, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=29.8245614035088, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24586117, Length=200, Percent_Identity=33, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI221330018, Length=200, Percent_Identity=33, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28754; Mature: 28754

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFDTHTHLNTIEFEGRVKEEISKAQSFGVTKINNVGSNYQLNDAALLLADKFESAYAT
CCCCCCCCCCEEEEECCHHHHHHHHHHHCCCEEECCCCCCEEECCCEEEEEHHHCCCEEE
IGWHPDDAAEFDTAAEEYLLTKGRSKKVIAVGEIGLDYHWMVSPKEVQERVFRRQIQISK
ECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHH
ELGIPFQVHTRDALSDTYEIIKSEGVRTAGAIMHSFSGTAEEALKFVELGMNISFSGVVT
HCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEHHHHH
FKKALDVQEAARLLPLDKILVETDAPYLTPTPYRGKENTPGYTKYVVEKIADLRGISMEE
HHHHHCHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
VAEATNENALKIFDLKK
HHHHCCCCCEEEEEECC
>Mature Secondary Structure
MEIFDTHTHLNTIEFEGRVKEEISKAQSFGVTKINNVGSNYQLNDAALLLADKFESAYAT
CCCCCCCCCCEEEEECCHHHHHHHHHHHCCCEEECCCCCCEEECCCEEEEEHHHCCCEEE
IGWHPDDAAEFDTAAEEYLLTKGRSKKVIAVGEIGLDYHWMVSPKEVQERVFRRQIQISK
ECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHH
ELGIPFQVHTRDALSDTYEIIKSEGVRTAGAIMHSFSGTAEEALKFVELGMNISFSGVVT
HCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEHHHHH
FKKALDVQEAARLLPLDKILVETDAPYLTPTPYRGKENTPGYTKYVVEKIADLRGISMEE
HHHHHCHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
VAEATNENALKIFDLKK
HHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]