Click here to switch to the map view.

The map label for this gene is menC [H]

Identifier: 125624622

GI number: 125624622

Start: 1814062

End: 1815174

Strand: Direct

Name: menC [H]

Synonym: llmg_1833

Alternate gene names: 125624622

Gene position: 1814062-1815174 (Clockwise)

Preceding gene: 125624621

Following gene: 125624623

Centisome position: 71.72

GC content: 36.12

Gene sequence:

>1113_bases
ATGAAAATTGAAAAAATCACAATGTTTCATGTTCAACTCCCCATGAAATTCAATTTTAAGACCGCCAAAGGTTCCTTAAA
TCTCCGTGATACAATTATTATAAAAGTTGAAAGTCCTAAGGGCCTTTCCGGATTTGGTGAAGTTGTTGCTTTCACGACTC
CTTTTTATACCTTAGAAACTTTTGCTAATTGTTGGAAAATTTTGGAAGAAACTTACCTGCCAGAAATTTTGCAAAAGGAA
TTCTCACACCCTTTTGAAATACATGAATTTTTTAGAAGTCCCTTACCAATGGCACTGGCTGGACTTGAAAATGCGCTTCT
AGATTTGTATTTTAAAGAAAAAAACGAAAATTTGATTGCTGGACTTTTCAAAGAAAAATTAGCTGATAAAATCCCACGTG
GTGCGGTTATTGGACAAATGTCTGACGAGCAAACCATTAAGCAAATTGACCAACTTATTAATAGTGGCGTCAAAAGAATT
AAATTAAAAATTAGTCCACAAATTGGGACTGACTTGATTAAAAAGCTGGTAAAAAGATATCCACAAATTACATTTGCTCT
TGATGCCAATCGAAGTTTTCAACTGACAGACTGGCCAGTCATCAAAGAGCTGGACAAACTTGGTCTGGCTTGTATCGAAG
AGCCTTTTGATATCAAAGATTTATCCGAATTAAAATTACTGACAGAAAACTTCTTAACACCAATTTGCTTTGACGAATCT
GTTCAAGATTTGGAAAGTCTAAAAATGCTGACAAAACTTCCTTTCAAAACCATGCTCAATGTGAAAATTGGTCGTTTAGG
CGGACTTTACCAAAGTCAAAAAGCTATTGAATTTTGCAGACAGCATCAGATTGGCTTTTGGATTGGCAGTATGGTTGAGT
CTGGCATCTCAAAAATACTCCATGTCCAACTCGCCGCGCTTTCTGGAAATGCTATGGCCGGTGATTTATCTGATTCTAAG
CATTATTTTGACCAAGACCTAATCAAACCAGAAATTTCTTTCCCAGAGGGATTTATGACTGTCCCTACTGGAGCTGGCAT
TGGCGTTACAATCAATGAAGAAATTCTAAATCGTTATACTGTAAATAAATTGAGCTTGACCTCCTTGAAATGA

Upstream 100 bases:

>100_bases
CTGAAAAGCTTGCAAAATATAAGCGTCCGCAGACCATCATTTTCATGGATGAATTGCCCAAAAACGCTTCTGGAAAAATC
TTAAGAAAAGAGCTCAAAGC

Downstream 100 bases:

>100_bases
ACGAAAAAAGAAAAAACTGGAACCTGGACTTACAAGTGAATTTTACTTCGCAAATCCCTTCCATAATCTTGAAGCTCTGC
TTCAAGCAGAACAACTTTTT

Product: o-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKIEKITMFHVQLPMKFNFKTAKGSLNLRDTIIIKVESPKGLSGFGEVVAFTTPFYTLETFANCWKILEETYLPEILQKE
FSHPFEIHEFFRSPLPMALAGLENALLDLYFKEKNENLIAGLFKEKLADKIPRGAVIGQMSDEQTIKQIDQLINSGVKRI
KLKISPQIGTDLIKKLVKRYPQITFALDANRSFQLTDWPVIKELDKLGLACIEEPFDIKDLSELKLLTENFLTPICFDES
VQDLESLKMLTKLPFKTMLNVKIGRLGGLYQSQKAIEFCRQHQIGFWIGSMVESGISKILHVQLAALSGNAMAGDLSDSK
HYFDQDLIKPEISFPEGFMTVPTGAGIGVTINEEILNRYTVNKLSLTSLK

Sequences:

>Translated_370_residues
MKIEKITMFHVQLPMKFNFKTAKGSLNLRDTIIIKVESPKGLSGFGEVVAFTTPFYTLETFANCWKILEETYLPEILQKE
FSHPFEIHEFFRSPLPMALAGLENALLDLYFKEKNENLIAGLFKEKLADKIPRGAVIGQMSDEQTIKQIDQLINSGVKRI
KLKISPQIGTDLIKKLVKRYPQITFALDANRSFQLTDWPVIKELDKLGLACIEEPFDIKDLSELKLLTENFLTPICFDES
VQDLESLKMLTKLPFKTMLNVKIGRLGGLYQSQKAIEFCRQHQIGFWIGSMVESGISKILHVQLAALSGNAMAGDLSDSK
HYFDQDLIKPEISFPEGFMTVPTGAGIGVTINEEILNRYTVNKLSLTSLK
>Mature_370_residues
MKIEKITMFHVQLPMKFNFKTAKGSLNLRDTIIIKVESPKGLSGFGEVVAFTTPFYTLETFANCWKILEETYLPEILQKE
FSHPFEIHEFFRSPLPMALAGLENALLDLYFKEKNENLIAGLFKEKLADKIPRGAVIGQMSDEQTIKQIDQLINSGVKRI
KLKISPQIGTDLIKKLVKRYPQITFALDANRSFQLTDWPVIKELDKLGLACIEEPFDIKDLSELKLLTENFLTPICFDES
VQDLESLKMLTKLPFKTMLNVKIGRLGGLYQSQKAIEFCRQHQIGFWIGSMVESGISKILHVQLAALSGNAMAGDLSDSK
HYFDQDLIKPEISFPEGFMTVPTGAGIGVTINEEILNRYTVNKLSLTSLK

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI87081876, Length=293, Percent_Identity=23.5494880546075, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 41845; Mature: 41845

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEKITMFHVQLPMKFNFKTAKGSLNLRDTIIIKVESPKGLSGFGEVVAFTTPFYTLET
CCCEEEEEEEEEECEEEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHEEECCHHHHHH
FANCWKILEETYLPEILQKEFSHPFEIHEFFRSPLPMALAGLENALLDLYFKEKNENLIA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHH
GLFKEKLADKIPRGAVIGQMSDEQTIKQIDQLINSGVKRIKLKISPQIGTDLIKKLVKRY
HHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHC
PQITFALDANRSFQLTDWPVIKELDKLGLACIEEPFDIKDLSELKLLTENFLTPICFDES
CCEEEEEECCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHH
VQDLESLKMLTKLPFKTMLNVKIGRLGGLYQSQKAIEFCRQHQIGFWIGSMVESGISKIL
HHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HVQLAALSGNAMAGDLSDSKHYFDQDLIKPEISFPEGFMTVPTGAGIGVTINEEILNRYT
HHHHEEECCCCEECCCCCCHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEECHHHHHHHC
VNKLSLTSLK
CCCEEECCCC
>Mature Secondary Structure
MKIEKITMFHVQLPMKFNFKTAKGSLNLRDTIIIKVESPKGLSGFGEVVAFTTPFYTLET
CCCEEEEEEEEEECEEEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHEEECCHHHHHH
FANCWKILEETYLPEILQKEFSHPFEIHEFFRSPLPMALAGLENALLDLYFKEKNENLIA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHH
GLFKEKLADKIPRGAVIGQMSDEQTIKQIDQLINSGVKRIKLKISPQIGTDLIKKLVKRY
HHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHC
PQITFALDANRSFQLTDWPVIKELDKLGLACIEEPFDIKDLSELKLLTENFLTPICFDES
CCEEEEEECCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHH
VQDLESLKMLTKLPFKTMLNVKIGRLGGLYQSQKAIEFCRQHQIGFWIGSMVESGISKIL
HHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HVQLAALSGNAMAGDLSDSKHYFDQDLIKPEISFPEGFMTVPTGAGIGVTINEEILNRYT
HHHHEEECCCCEECCCCCCHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEECHHHHHHHC
VNKLSLTSLK
CCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]