Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 125624575

GI number: 125624575

Start: 1765337

End: 1766257

Strand: Reverse

Name: fabD [H]

Synonym: llmg_1785

Alternate gene names: 125624575

Gene position: 1766257-1765337 (Counterclockwise)

Preceding gene: 125624576

Following gene: 125624574

Centisome position: 69.83

GC content: 37.13

Gene sequence:

>921_bases
ATGACTAAAACAGCATTTTTATTCTCGGGTCAGGGCGCACAACAGCTAGGAATGGCTCGTGATTTATATGACCAACACGA
ATCGGTAAAAACGACTTTTGATGAAGCAAGCAAAGCTTTAGGATATGACTTACGTGCTTTGATTGATCATGATGAAGAAA
AATTAAATGAAACAGAATATACACAACCTGCTATTTTGACAACTTCTGTTGCCATTATGCGATTGTTGAATGAAAATGGA
ATAAAACCCGACGTAGTTGCTGGGCTTAGTCTTGGTGAGTACTCAGCATTAGTTGCTTCAGGAATTATTGATTTTCAAGA
AGCAGTTAAGCTTGTAGCTAAACGTGGTCAATACATGACAGAAGCTGCTCCGACTGGTTCAGGTAAAATGGTTGCAGTAA
TGAATACAGAGCCTGCTTTGATTGAAGAGATTTGTCAAAAAGCATCTGAGCGTGGCATTGTGAGCCCGGCAAATTACAAT
ACGCCCGCACAAATTGTTATTGGTGGTGAAGTTTTAGCCGTTGATTACGCCGTTGAATTATTAAAAGAGGCAGGGGTTCG
TAAACTGATTGAATTAAAAGTATCAGGACCTTTCCATACAGCTATTCTTAAGCCAGCTTCTGAAAAATTAGCTTTGGAAC
TTGATAAAATTAATTTTAAATCTTTTGAATTACCTTTAATTTCAAATACTAGCGCTAAAGTAATGCAAGAGGATGAGGTC
AAAGCCTTGTTAACTCGCCAAGTAATGGAACCTGTCCGTTTTTATGAATCTGTTGAAACAATGCAAAAAGTAGGAGTGAC
TCGCTTTATTGAAGTTGGTCCTGGAAAAGTACTTTCTGGTTTCATAAAGAAAATTGATAAAAATGCAGAATTTACAAATG
TTTGTGATGTTGCTACATTTGAAGCCTTGATTAGTCAGTAA

Upstream 100 bases:

>100_bases
ACAATACTAATAATTAACTTTATAAAAGAAAATACGAGGAATTCTAATCTACTAGTTTGAATAGCTTATTTGAATTCGAA
ATAGTTGATTACTATATATT

Downstream 100 bases:

>100_bases
AATTGGAGAAAGGAATTGAGTTCGTCCTTCTAAACAGTCAACGATAATCTGACATCAGATTATTGCTGTCCCTGAAGTCT
AAGCACTAAAGTGCTAAGAC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTKTAFLFSGQGAQQLGMARDLYDQHESVKTTFDEASKALGYDLRALIDHDEEKLNETEYTQPAILTTSVAIMRLLNENG
IKPDVVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMTEAAPTGSGKMVAVMNTEPALIEEICQKASERGIVSPANYN
TPAQIVIGGEVLAVDYAVELLKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKINFKSFELPLISNTSAKVMQEDEV
KALLTRQVMEPVRFYESVETMQKVGVTRFIEVGPGKVLSGFIKKIDKNAEFTNVCDVATFEALISQ

Sequences:

>Translated_306_residues
MTKTAFLFSGQGAQQLGMARDLYDQHESVKTTFDEASKALGYDLRALIDHDEEKLNETEYTQPAILTTSVAIMRLLNENG
IKPDVVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMTEAAPTGSGKMVAVMNTEPALIEEICQKASERGIVSPANYN
TPAQIVIGGEVLAVDYAVELLKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKINFKSFELPLISNTSAKVMQEDEV
KALLTRQVMEPVRFYESVETMQKVGVTRFIEVGPGKVLSGFIKKIDKNAEFTNVCDVATFEALISQ
>Mature_305_residues
TKTAFLFSGQGAQQLGMARDLYDQHESVKTTFDEASKALGYDLRALIDHDEEKLNETEYTQPAILTTSVAIMRLLNENGI
KPDVVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMTEAAPTGSGKMVAVMNTEPALIEEICQKASERGIVSPANYNT
PAQIVIGGEVLAVDYAVELLKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKINFKSFELPLISNTSAKVMQEDEVK
ALLTRQVMEPVRFYESVETMQKVGVTRFIEVGPGKVLSGFIKKIDKNAEFTNVCDVATFEALISQ

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=309, Percent_Identity=31.7152103559871, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI41872631, Length=292, Percent_Identity=26.7123287671233, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI27477045, Length=111, Percent_Identity=37.8378378378378, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=47.2222222222222, Blast_Score=250, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=31.6151202749141, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=300, Percent_Identity=28.6666666666667, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24665753, Length=306, Percent_Identity=30.718954248366, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33412; Mature: 33281

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTAFLFSGQGAQQLGMARDLYDQHESVKTTFDEASKALGYDLRALIDHDEEKLNETEY
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHCCCCCC
TQPAILTTSVAIMRLLNENGIKPDVVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMT
CCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EAAPTGSGKMVAVMNTEPALIEEICQKASERGIVSPANYNTPAQIVIGGEVLAVDYAVEL
HCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEHHHHHHHH
LKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKINFKSFELPLISNTSAKVMQEDEV
HHHHCHHEEEEEEECCCCHHHHCCCCCHHHEEEEECCCCCEEECCEECCCHHHHHHHHHH
KALLTRQVMEPVRFYESVETMQKVGVTRFIEVGPGKVLSGFIKKIDKNAEFTNVCDVATF
HHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHH
EALISQ
HHHHCC
>Mature Secondary Structure 
TKTAFLFSGQGAQQLGMARDLYDQHESVKTTFDEASKALGYDLRALIDHDEEKLNETEY
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHCCCCCC
TQPAILTTSVAIMRLLNENGIKPDVVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMT
CCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EAAPTGSGKMVAVMNTEPALIEEICQKASERGIVSPANYNTPAQIVIGGEVLAVDYAVEL
HCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEHHHHHHHH
LKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKINFKSFELPLISNTSAKVMQEDEV
HHHHCHHEEEEEEECCCCHHHHCCCCCHHHEEEEECCCCCEEECCEECCCHHHHHHHHHH
KALLTRQVMEPVRFYESVETMQKVGVTRFIEVGPGKVLSGFIKKIDKNAEFTNVCDVATF
HHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHH
EALISQ
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]