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The map label for this gene is bglA [H]

Identifier: 125624529

GI number: 125624529

Start: 1716819

End: 1718180

Strand: Reverse

Name: bglA [H]

Synonym: llmg_1738

Alternate gene names: 125624529

Gene position: 1718180-1716819 (Counterclockwise)

Preceding gene: 125624530

Following gene: 125624528

Centisome position: 67.93

GC content: 34.21

Gene sequence:

>1362_bases
ATGGAAAATAAAATGCCAAAAGATTTTTTCTGGGGGAATTCAACTTCGTCAATGCAAACCGAAGGCGGCTGGAATGAAGG
AGGAAAAGGGCCCTCTGTCTATGATGTGAATACCGCTGGACGTTCTGCCAAAGATTGGCAAGTAACAAATGATAATTATC
ATCATTATTCCCAAGATCTAGATCTTATGAAAGAAATGAATATGAATATGTATCGTTTCCAAATTTCTTGGTCACGAATT
GTTCCTGACGGCGATGGTGAATTTAATGAGGAAGGAATTGCCTTTTATAATCGTCTGATTGATGATTTGCTGGCTCGTGG
AATTGAGCCTATGATATGTCTCTATCATTTCGATATGCCATTAAATCTGGCTGAAAAGTACAATGGTTTTTTGAGTCGAA
AAGTGAAAGAAGCATTTGTAAGATTTGGGCAAGAAATGATGAAAAGATTTGCTGACAAAGTCAAATATTGGATTGTTTTT
AATGAGCATAATCTTTATTTTGCTGACGGTTTTGAGCATTATTCGGGAGTTTTGAAAAAAGAGCTGACGCTCTCTGATAT
GTATACTGTTTTTCATCACACCATGCTTGCTCATTGCGAATTAACCCAATTTTTGCATGAAAATTTTGAAGCAAAAATAG
GAGGAATGTTGGCGACTACGGAAATATATCCCGCAACTTTTTCACCAAAAGATAATTTATATCTTAGAAAATTTGATGAA
TTTTATAATCGAAATCTCTGTGATGTTTATGCTTTTGGTCATTATTCGCATGAGGTTATGACCTATGTTAAAAATCAGAA
CATCCAAATGGATTTTCAAAAAGGAGATGAAGAAATTTTAAAAAATGGAATTTCTGACTTTATTTCTTTTTCTTATTATC
GCTCAATTTTACTTGATGCAAGTCAGCTGACAGAAAATGATGCACCAAATTCTTATTTGACTAAAGGAATGAAATTAAAT
CCGTTGCTTGAACATAATCAATGGGATTGGTCCATTGACCCAGAAGGCTTTAGAAGAATTCTAAGTAGATTATATAATGA
ATTTGGATTGCCTGTTTTTCCTATTGAAAATGGCATTGGTCAGTCAGAAATCTGGGATGGGAAAACAAAAATTGCTGATG
ACTTGAGAATTTTTTATCATCAGAAACATCTTGAAGCCATGAAAAAGGCAATATTTACTGACGGGGTAGAAGTTATGGGT
TATCTTGGTTGGGGATTGATTGATATTCCTGCTTCATCTGGTGCTATTGATAAACGTTACGGTGCTGTTTATGTGGATCC
AAAAAGTCATAAACGTATTCCAAAAAAATCATTTCATTGGTTTAAAAATGTTTTTGCTTCAAATGGTGATCATTTGGATT
AG

Upstream 100 bases:

>100_bases
AGAAGTAATTGCTTAGTAATTGAATAAGGAGATTAGAAACTCCGGAGAAACTTTTTCTTCGGGATTTCTTTTTATAAAAT
TAAAGATAAAAGGGGACAAA

Downstream 100 bases:

>100_bases
AATAATCAGTGATAAAAATGAAATAATGATAGAAAACTTATGATTTACTCATATCTCTTAATTAAACTGATAGCTAGGCT
GTCAGTTTTTAAATTCATCA

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MENKMPKDFFWGNSTSSMQTEGGWNEGGKGPSVYDVNTAGRSAKDWQVTNDNYHHYSQDLDLMKEMNMNMYRFQISWSRI
VPDGDGEFNEEGIAFYNRLIDDLLARGIEPMICLYHFDMPLNLAEKYNGFLSRKVKEAFVRFGQEMMKRFADKVKYWIVF
NEHNLYFADGFEHYSGVLKKELTLSDMYTVFHHTMLAHCELTQFLHENFEAKIGGMLATTEIYPATFSPKDNLYLRKFDE
FYNRNLCDVYAFGHYSHEVMTYVKNQNIQMDFQKGDEEILKNGISDFISFSYYRSILLDASQLTENDAPNSYLTKGMKLN
PLLEHNQWDWSIDPEGFRRILSRLYNEFGLPVFPIENGIGQSEIWDGKTKIADDLRIFYHQKHLEAMKKAIFTDGVEVMG
YLGWGLIDIPASSGAIDKRYGAVYVDPKSHKRIPKKSFHWFKNVFASNGDHLD

Sequences:

>Translated_453_residues
MENKMPKDFFWGNSTSSMQTEGGWNEGGKGPSVYDVNTAGRSAKDWQVTNDNYHHYSQDLDLMKEMNMNMYRFQISWSRI
VPDGDGEFNEEGIAFYNRLIDDLLARGIEPMICLYHFDMPLNLAEKYNGFLSRKVKEAFVRFGQEMMKRFADKVKYWIVF
NEHNLYFADGFEHYSGVLKKELTLSDMYTVFHHTMLAHCELTQFLHENFEAKIGGMLATTEIYPATFSPKDNLYLRKFDE
FYNRNLCDVYAFGHYSHEVMTYVKNQNIQMDFQKGDEEILKNGISDFISFSYYRSILLDASQLTENDAPNSYLTKGMKLN
PLLEHNQWDWSIDPEGFRRILSRLYNEFGLPVFPIENGIGQSEIWDGKTKIADDLRIFYHQKHLEAMKKAIFTDGVEVMG
YLGWGLIDIPASSGAIDKRYGAVYVDPKSHKRIPKKSFHWFKNVFASNGDHLD
>Mature_453_residues
MENKMPKDFFWGNSTSSMQTEGGWNEGGKGPSVYDVNTAGRSAKDWQVTNDNYHHYSQDLDLMKEMNMNMYRFQISWSRI
VPDGDGEFNEEGIAFYNRLIDDLLARGIEPMICLYHFDMPLNLAEKYNGFLSRKVKEAFVRFGQEMMKRFADKVKYWIVF
NEHNLYFADGFEHYSGVLKKELTLSDMYTVFHHTMLAHCELTQFLHENFEAKIGGMLATTEIYPATFSPKDNLYLRKFDE
FYNRNLCDVYAFGHYSHEVMTYVKNQNIQMDFQKGDEEILKNGISDFISFSYYRSILLDASQLTENDAPNSYLTKGMKLN
PLLEHNQWDWSIDPEGFRRILSRLYNEFGLPVFPIENGIGQSEIWDGKTKIADDLRIFYHQKHLEAMKKAIFTDGVEVMG
YLGWGLIDIPASSGAIDKRYGAVYVDPKSHKRIPKKSFHWFKNVFASNGDHLD

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=474, Percent_Identity=28.4810126582279, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI32481206, Length=476, Percent_Identity=29.2016806722689, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI13273313, Length=481, Percent_Identity=26.6112266112266, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI28376633, Length=475, Percent_Identity=27.1578947368421, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI24497614, Length=479, Percent_Identity=26.9311064718163, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI190360571, Length=95, Percent_Identity=35.7894736842105, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI2367174, Length=477, Percent_Identity=37.9454926624738, Blast_Score=304, Evalue=9e-84,
Organism=Escherichia coli, GI1789070, Length=476, Percent_Identity=35.7142857142857, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI2367270, Length=468, Percent_Identity=36.3247863247863, Blast_Score=278, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17552856, Length=473, Percent_Identity=29.8097251585624, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17539390, Length=464, Percent_Identity=27.801724137931, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21356577, Length=490, Percent_Identity=26.734693877551, Blast_Score=154, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 52830; Mature: 52830

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKMPKDFFWGNSTSSMQTEGGWNEGGKGPSVYDVNTAGRSAKDWQVTNDNYHHYSQDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHH
DLMKEMNMNMYRFQISWSRIVPDGDGEFNEEGIAFYNRLIDDLLARGIEPMICLYHFDMP
HHHHHCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
LNLAEKYNGFLSRKVKEAFVRFGQEMMKRFADKVKYWIVFNEHNLYFADGFEHYSGVLKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCEEEECCHHHHHHHHHH
ELTLSDMYTVFHHTMLAHCELTQFLHENFEAKIGGMLATTEIYPATFSPKDNLYLRKFDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCCCCCCHHHHHHHH
FYNRNLCDVYAFGHYSHEVMTYVKNQNIQMDFQKGDEEILKNGISDFISFSYYRSILLDA
HHCCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SQLTENDAPNSYLTKGMKLNPLLEHNQWDWSIDPEGFRRILSRLYNEFGLPVFPIENGIG
HHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCC
QSEIWDGKTKIADDLRIFYHQKHLEAMKKAIFTDGVEVMGYLGWGLIDIPASSGAIDKRY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCCCCC
GAVYVDPKSHKRIPKKSFHWFKNVFASNGDHLD
CEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MENKMPKDFFWGNSTSSMQTEGGWNEGGKGPSVYDVNTAGRSAKDWQVTNDNYHHYSQDL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHH
DLMKEMNMNMYRFQISWSRIVPDGDGEFNEEGIAFYNRLIDDLLARGIEPMICLYHFDMP
HHHHHCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
LNLAEKYNGFLSRKVKEAFVRFGQEMMKRFADKVKYWIVFNEHNLYFADGFEHYSGVLKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCEEEECCHHHHHHHHHH
ELTLSDMYTVFHHTMLAHCELTQFLHENFEAKIGGMLATTEIYPATFSPKDNLYLRKFDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEEEECCCCCCCCCHHHHHHHH
FYNRNLCDVYAFGHYSHEVMTYVKNQNIQMDFQKGDEEILKNGISDFISFSYYRSILLDA
HHCCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SQLTENDAPNSYLTKGMKLNPLLEHNQWDWSIDPEGFRRILSRLYNEFGLPVFPIENGIG
HHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCC
QSEIWDGKTKIADDLRIFYHQKHLEAMKKAIFTDGVEVMGYLGWGLIDIPASSGAIDKRY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCCCCC
GAVYVDPKSHKRIPKKSFHWFKNVFASNGDHLD
CEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]