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The map label for this gene is choS [H]

Identifier: 125624494

GI number: 125624494

Start: 1674398

End: 1675900

Strand: Reverse

Name: choS [H]

Synonym: llmg_1699

Alternate gene names: 125624494

Gene position: 1675900-1674398 (Counterclockwise)

Preceding gene: 125624495

Following gene: 125624493

Centisome position: 66.25

GC content: 35.4

Gene sequence:

>1503_bases
ATGAGCCAATTAATTTCAACTTTTCAAAATCAGCAAGGACAATTTTGGCAGGCACTTTTGGAACATATTCAAATCTCACT
CATTTCAATTTTTATTGCGATTTTGATTTCGATTCCCTTAGCCCTCTTACTTCGACGTTTTCCGAAAATTGCCGAACCGA
TTTTGCAAGTCACAGGAATTTTTCAAACCATTCCTAGTTTAGCTCTTTTGGGATTATTAATTCCATTTATCGGAATTGGA
AGTTTACCAGCCATTGTTGCACTTGTTGTTTATGCGATTTTTCCAATTGTTCAAAATACATATACGGGTTTAGAGCAAAT
TGAACCTTCCTTGATTGAGGCCGCAACGGCATTTGGGATGAATCGCAGGGAACGACTGATGAAATTTGAACTCTCATTGG
CAATGCCCTTTATCATGGCAGGAATTCGGACGAGTACAGTTATGGTCATTGGTACCGCGACACTCGCTGCCCTGATTGGC
GCTGGAGGTTTAGGAAACTTTATTCTTCTTGGAATAAATATGAATGATGTTTCATTGATTTTGATTGGAGCCATTTCGTC
AGCCTTGTTGGCGATCATTTTCAGTAGTCTTTTGAAATTTTTAGAGAAGGCAAAGATAAGAACAATTCTCATTAGTTTTT
TCATTGGTTTACTCGTGTTGGGAGGTTCTTACTATCGCCCTCAAACTTCTGACCATCCACAAATTACAATTGCAGGTAAA
TTAGGAGCTGAACCTGATGTATTGATTAACATGTACAAGTTACTTATTGAGAAGGATAGTAATATTCGTGTCAATTTAAA
ATCAAATTTTGGTGATACGACTTTCCTCTATAATGCCTTAAAAGCAGGAAAAATTGATATCTATCCTGAATACACAGGGA
CGATTACTTCTACATTTTTAAAAGACCCAGTTAATTCTACTGACCCGGCTGTAGTTTGGCAAAAAGCAGAAGAAGGCATT
AAAAAACTCAATCAATTTACCTACCTATCACCAATGAAATTTCAAGATACTTATGCTCTTGCTGTCAAATCTGATTTTGC
TAAAGAACATCAGCTCACGAAAATTTCTGATTTGCCTAACGTTTCAGGATTAACTGCAGGTTTTGATGTTGAATTTGCTA
ATCGTTCAGATGGAAATATTGGCTTGAAAAAACTATATGGACTTGATTTAAATGTCAAAACCATGCAAAGTAGTCTGATT
TATAATGCCTTAAACTCTGGGGCTGTGAATGTCGCTGAAGTATATTCTACTGACAGCCAAATTAAACAATATAATCTTAC
TGTTTTAAAAGATGATAAGAACCTTTTTCCACCTTATCAAGCAGCACCACTGATGAAAGAAAGTTTATTAAAAAAATATC
CTGAACTCAAGAAGATTCTCAATAAACTGTCAGGAAAAATTACTGACCAAGAGATGATTGAGATGAACTATGATGTTAAT
GTTAAGCAGGAAGACGCTTCAAAAGTAGCAGAAAGATATTTAAAAGCTAAAGGATTAATTTAA

Upstream 100 bases:

>100_bases
CTGAAATAATCAATCGTCTATCTGAAAAAGAAGTTTTGAAATACAGGGGCAAAAGCATCACCTCAGATGATATTATTTGT
TATATTGCAGGAGGTGAAAA

Downstream 100 bases:

>100_bases
AAGAAAAAGACCATTGTATAATGGTCTTTTTGATTTAGAGGAGGAGAAAATATAAATGCGCGAGTAAGAACACAACATAA
GATATTTCAGCCTTCTATTG

Product: choline ABC transporter permease and substrate binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MSQLISTFQNQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRFPKIAEPILQVTGIFQTIPSLALLGLLIPFIGIG
SLPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGMNRRERLMKFELSLAMPFIMAGIRTSTVMVIGTATLAALIG
AGGLGNFILLGINMNDVSLILIGAISSALLAIIFSSLLKFLEKAKIRTILISFFIGLLVLGGSYYRPQTSDHPQITIAGK
LGAEPDVLINMYKLLIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDIYPEYTGTITSTFLKDPVNSTDPAVVWQKAEEGI
KKLNQFTYLSPMKFQDTYALAVKSDFAKEHQLTKISDLPNVSGLTAGFDVEFANRSDGNIGLKKLYGLDLNVKTMQSSLI
YNALNSGAVNVAEVYSTDSQIKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVN
VKQEDASKVAERYLKAKGLI

Sequences:

>Translated_500_residues
MSQLISTFQNQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRFPKIAEPILQVTGIFQTIPSLALLGLLIPFIGIG
SLPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGMNRRERLMKFELSLAMPFIMAGIRTSTVMVIGTATLAALIG
AGGLGNFILLGINMNDVSLILIGAISSALLAIIFSSLLKFLEKAKIRTILISFFIGLLVLGGSYYRPQTSDHPQITIAGK
LGAEPDVLINMYKLLIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDIYPEYTGTITSTFLKDPVNSTDPAVVWQKAEEGI
KKLNQFTYLSPMKFQDTYALAVKSDFAKEHQLTKISDLPNVSGLTAGFDVEFANRSDGNIGLKKLYGLDLNVKTMQSSLI
YNALNSGAVNVAEVYSTDSQIKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVN
VKQEDASKVAERYLKAKGLI
>Mature_499_residues
SQLISTFQNQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRFPKIAEPILQVTGIFQTIPSLALLGLLIPFIGIGS
LPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGMNRRERLMKFELSLAMPFIMAGIRTSTVMVIGTATLAALIGA
GGLGNFILLGINMNDVSLILIGAISSALLAIIFSSLLKFLEKAKIRTILISFFIGLLVLGGSYYRPQTSDHPQITIAGKL
GAEPDVLINMYKLLIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDIYPEYTGTITSTFLKDPVNSTDPAVVWQKAEEGIK
KLNQFTYLSPMKFQDTYALAVKSDFAKEHQLTKISDLPNVSGLTAGFDVEFANRSDGNIGLKKLYGLDLNVKTMQSSLIY
NALNSGAVNVAEVYSTDSQIKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVNV
KQEDASKVAERYLKAKGLI

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788452, Length=308, Percent_Identity=28.8961038961039, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788449, Length=197, Percent_Identity=38.5786802030457, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788451, Length=214, Percent_Identity=32.7102803738318, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789033, Length=171, Percent_Identity=34.5029239766082, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 55123; Mature: 54991

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLISTFQNQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRFPKIAEPILQVTGI
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQTIPSLALLGLLIPFIGIGSLPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHCC
NRRERLMKFELSLAMPFIMAGIRTSTVMVIGTATLAALIGAGGLGNFILLGINMNDVSLI
CHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
LIGAISSALLAIIFSSLLKFLEKAKIRTILISFFIGLLVLGGSYYRPQTSDHPQITIAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEC
LGAEPDVLINMYKLLIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDIYPEYTGTITSTFL
CCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEECCCCCCHHHHHHH
KDPVNSTDPAVVWQKAEEGIKKLNQFTYLSPMKFQDTYALAVKSDFAKEHQLTKISDLPN
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCC
VSGLTAGFDVEFANRSDGNIGLKKLYGLDLNVKTMQSSLIYNALNSGAVNVAEVYSTDSQ
CCCCCCCCEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCHHH
IKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVN
HHHEEEEEEECCCCCCCCHHCCHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHCCCCCC
VKQEDASKVAERYLKAKGLI
CCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQLISTFQNQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRFPKIAEPILQVTGI
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQTIPSLALLGLLIPFIGIGSLPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHCC
NRRERLMKFELSLAMPFIMAGIRTSTVMVIGTATLAALIGAGGLGNFILLGINMNDVSLI
CHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
LIGAISSALLAIIFSSLLKFLEKAKIRTILISFFIGLLVLGGSYYRPQTSDHPQITIAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEC
LGAEPDVLINMYKLLIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDIYPEYTGTITSTFL
CCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEECCCCCCHHHHHHH
KDPVNSTDPAVVWQKAEEGIKKLNQFTYLSPMKFQDTYALAVKSDFAKEHQLTKISDLPN
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCC
VSGLTAGFDVEFANRSDGNIGLKKLYGLDLNVKTMQSSLIYNALNSGAVNVAEVYSTDSQ
CCCCCCCCEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCHHH
IKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVN
HHHEEEEEEECCCCCCCCHHCCHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHCCCCCC
VKQEDASKVAERYLKAKGLI
CCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592481; 10216873; 9384377 [H]