Click here to switch to the map view.

The map label for this gene is comFA [H]

Identifier: 125624289

GI number: 125624289

Start: 1457104

End: 1458396

Strand: Direct

Name: comFA [H]

Synonym: llmg_1483

Alternate gene names: 125624289

Gene position: 1457104-1458396 (Clockwise)

Preceding gene: 125624280

Following gene: 125624290

Centisome position: 57.6

GC content: 34.65

Gene sequence:

>1293_bases
ATGAACTTAATTTTAGAAAATCTCCTTGGGCGTCTTTTACTAGAAAAAGATATTTCAGCTTTTTATAATTTTACTGACCA
AGTTAACAATGAAAATAAATTAATTAAAATTTGTGCAATGACATCTGTCAGTGCTAATAAAGTAAGATGTAATCGATGTG
GCACGATACATATAAAAACCAATGTTAAACTTCCGATTGGTGCTTTTTTCTGTCCAACTTGTCTTGAACTTGGTCGTGTC
CGCTCAGATGAATATTTCTACCATCTTCCTCAACAAGACTTTCCAGAAAAAACTTATTTACGTTGGACTGGAAAATTAAC
AGAAAATCAAGAAAAAATTTCTAACGCTCTCTGTCAGCAAATTACTAATAATCAAAAACTACTTGTTCAAGCCGTTACTG
GTGCTGGTAAAACAGAAATGATATATCAGCTTATTGAACAAATTCTTAGCCATGGGGGTTCGGTCGGTTTAGCCAGCCCA
AGAATTGATGTATGCATTGAGCTTCATCAACGTTTATCACGTGATTTCACTTGTCAAATTCCCCTTTTGTATCATGAGGG
AGATTCTTATTTTCGTTCGCCTTTGGTCGTTATGACCAGTCACCAACTTTTACGTTTCAAAGAGGCCTTTGATTTGCTTA
TCATCGATGAAGTCGATGCCTTTCCTTTTAGAGATAATGACATGCTTTATTTCGCTCTTGAAAATGCTAAAAAAATTAAT
GGAAACTTGCTCTACTTAACCGCTACATCTACTGACAAATTAGACAAACAGATAAAAAAGCATGAAATTAAACGACTTTT
TTTACCACGCCGCTTTCACGGTCATCCTTTGGTCATTCCAATGTTTTTTTGGAAAAAAACATTTTATAAAAAATTCATTG
AGCAAAGAAAGACTGGTTTCCCACTTCTAATTTTCGTTGCCGAAATCGACTTTGGTCAAGACTTTGCCAAAAATTTACAA
GAAAAATTTCAAAAAGAAAGAATGGCTTTTGTCGCTTCAACAACTAAAAGCAGAAAAACGATTGTCGAAGCTTTTCGTAA
GAAACAAGTTTCGATTTTAATTACGACTTCTATTCTTGAACGAGGCGTAACTTTTTCTTCGATTGATGTTTTTGTCATTA
ATAGCGAACACCCTAATTTCACAAAATCTGCCCTCATTCAAATGGTCGGACGAGTGGGACGAGACTCTAAACGTCCAACA
GGATTAGTTAGTTTTTTTCACTCTGGAAAATCTTTAGCCATGTGTCAAGCTCAGAAAGAAATTAAAAAAATGAACCAACT
CGGAGGTTTTTAA

Upstream 100 bases:

>100_bases
ATTTCCTCTTCATTGATAAAATCAGTTTTTATAGTGATAGTCATGCTAATGATTTTAACAAAATTTGTTACATTTGAACA
GCATTTCCGTATAGTTAAGT

Downstream 100 bases:

>100_bases
TGCAAACATGTCTGCTTTGTTCCAGAATTATCAAACAAACACTCACTTTTAGTGAATTCTTTTTACTAAAGAATAAGAGA
AATTTAATATGCAATAAATG

Product: superfamily II DNA/RNA helicase

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MNLILENLLGRLLLEKDISAFYNFTDQVNNENKLIKICAMTSVSANKVRCNRCGTIHIKTNVKLPIGAFFCPTCLELGRV
RSDEYFYHLPQQDFPEKTYLRWTGKLTENQEKISNALCQQITNNQKLLVQAVTGAGKTEMIYQLIEQILSHGGSVGLASP
RIDVCIELHQRLSRDFTCQIPLLYHEGDSYFRSPLVVMTSHQLLRFKEAFDLLIIDEVDAFPFRDNDMLYFALENAKKIN
GNLLYLTATSTDKLDKQIKKHEIKRLFLPRRFHGHPLVIPMFFWKKTFYKKFIEQRKTGFPLLIFVAEIDFGQDFAKNLQ
EKFQKERMAFVASTTKSRKTIVEAFRKKQVSILITTSILERGVTFSSIDVFVINSEHPNFTKSALIQMVGRVGRDSKRPT
GLVSFFHSGKSLAMCQAQKEIKKMNQLGGF

Sequences:

>Translated_430_residues
MNLILENLLGRLLLEKDISAFYNFTDQVNNENKLIKICAMTSVSANKVRCNRCGTIHIKTNVKLPIGAFFCPTCLELGRV
RSDEYFYHLPQQDFPEKTYLRWTGKLTENQEKISNALCQQITNNQKLLVQAVTGAGKTEMIYQLIEQILSHGGSVGLASP
RIDVCIELHQRLSRDFTCQIPLLYHEGDSYFRSPLVVMTSHQLLRFKEAFDLLIIDEVDAFPFRDNDMLYFALENAKKIN
GNLLYLTATSTDKLDKQIKKHEIKRLFLPRRFHGHPLVIPMFFWKKTFYKKFIEQRKTGFPLLIFVAEIDFGQDFAKNLQ
EKFQKERMAFVASTTKSRKTIVEAFRKKQVSILITTSILERGVTFSSIDVFVINSEHPNFTKSALIQMVGRVGRDSKRPT
GLVSFFHSGKSLAMCQAQKEIKKMNQLGGF
>Mature_430_residues
MNLILENLLGRLLLEKDISAFYNFTDQVNNENKLIKICAMTSVSANKVRCNRCGTIHIKTNVKLPIGAFFCPTCLELGRV
RSDEYFYHLPQQDFPEKTYLRWTGKLTENQEKISNALCQQITNNQKLLVQAVTGAGKTEMIYQLIEQILSHGGSVGLASP
RIDVCIELHQRLSRDFTCQIPLLYHEGDSYFRSPLVVMTSHQLLRFKEAFDLLIIDEVDAFPFRDNDMLYFALENAKKIN
GNLLYLTATSTDKLDKQIKKHEIKRLFLPRRFHGHPLVIPMFFWKKTFYKKFIEQRKTGFPLLIFVAEIDFGQDFAKNLQ
EKFQKERMAFVASTTKSRKTIVEAFRKKQVSILITTSILERGVTFSSIDVFVINSEHPNFTKSALIQMVGRVGRDSKRPT
GLVSFFHSGKSLAMCQAQKEIKKMNQLGGF

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 49462; Mature: 49462

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLILENLLGRLLLEKDISAFYNFTDQVNNENKLIKICAMTSVSANKVRCNRCGTIHIKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEECCCCEEEEEE
NVKLPIGAFFCPTCLELGRVRSDEYFYHLPQQDFPEKTYLRWTGKLTENQEKISNALCQQ
CCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
ITNNQKLLVQAVTGAGKTEMIYQLIEQILSHGGSVGLASPRIDVCIELHQRLSRDFTCQI
HCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
PLLYHEGDSYFRSPLVVMTSHQLLRFKEAFDLLIIDEVDAFPFRDNDMLYFALENAKKIN
EEEEECCCHHHHCCEEEEHHHHHHHHHHHHCEEEEECCCCCCCCCCCEEEEEECCCEECC
GNLLYLTATSTDKLDKQIKKHEIKRLFLPRRFHGHPLVIPMFFWKKTFYKKFIEQRKTGF
CCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCC
PLLIFVAEIDFGQDFAKNLQEKFQKERMAFVASTTKSRKTIVEAFRKKQVSILITTSILE
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEEHHHHH
RGVTFSSIDVFVINSEHPNFTKSALIQMVGRVGRDSKRPTGLVSFFHSGKSLAMCQAQKE
CCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHH
IKKMNQLGGF
HHHHHHCCCC
>Mature Secondary Structure
MNLILENLLGRLLLEKDISAFYNFTDQVNNENKLIKICAMTSVSANKVRCNRCGTIHIKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEECCCCEEEEEE
NVKLPIGAFFCPTCLELGRVRSDEYFYHLPQQDFPEKTYLRWTGKLTENQEKISNALCQQ
CCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
ITNNQKLLVQAVTGAGKTEMIYQLIEQILSHGGSVGLASPRIDVCIELHQRLSRDFTCQI
HCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
PLLYHEGDSYFRSPLVVMTSHQLLRFKEAFDLLIIDEVDAFPFRDNDMLYFALENAKKIN
EEEEECCCHHHHCCEEEEHHHHHHHHHHHHCEEEEECCCCCCCCCCCEEEEEECCCEECC
GNLLYLTATSTDKLDKQIKKHEIKRLFLPRRFHGHPLVIPMFFWKKTFYKKFIEQRKTGF
CCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCC
PLLIFVAEIDFGQDFAKNLQEKFQKERMAFVASTTKSRKTIVEAFRKKQVSILITTSILE
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEEHHHHH
RGVTFSSIDVFVINSEHPNFTKSALIQMVGRVGRDSKRPTGLVSFFHSGKSLAMCQAQKE
CCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHH
IKKMNQLGGF
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]