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The map label for this gene is murQ [H]

Identifier: 125624238

GI number: 125624238

Start: 1394669

End: 1395562

Strand: Reverse

Name: murQ [H]

Synonym: llmg_1427

Alternate gene names: 125624238

Gene position: 1395562-1394669 (Counterclockwise)

Preceding gene: 125624239

Following gene: 125624237

Centisome position: 55.17

GC content: 36.8

Gene sequence:

>894_bases
ATGATTGATTTATCAACACTAACAACAGAACGACGAAATGACGAAACATTTAACCTTGATCAAATGACCGTAAAAGAAGC
ACTTGTCAAAATGAACAATGAAGATAAGAAAGTAGCTTATGCGGTAGAAGAAGCATTACCAAATATTGAACCAGTTATTT
CATCAGCAATAGAAGCTTTTAACAAAGGTGGCCGTTTGATTTATATGGGAGCTGGAACAAGTGGTCGTCTGGGGGTTCTT
GATGCGGCTGAATGTGTCCCAACTTTTGGTGTGCCAGCAACGCAAGTCGTTGGTTTAATCGCTGGAGGAGACAAGGCAAT
GACAGTCGCAGTTGAAGGAGCTGAGGATAGTTTAGAACTAGGTAGACAAGATTTAATTGACTTAAATTTGTCAGAAAATG
ATCTAGTTTTGGGAATTGCTGCAAGTGGACGAACACCTTATGTGATTGGTGCTTTAGACTATGCAAAAGAAATTGGTGCT
AAAAGAGCCAGTCTTTCTTGTAATCTTAATGCTGAAATTTCAAAACATGCTGAATTTCCGATTGAAGTTGACTGTGGTCC
AGAATTTTTAACTGGTTCTACTCGCTTGAAATCAGGGACAGCTCAAAAATTAATTTTGAATATGATTTCAACAATTTCAA
TGATTGGAATCGGGAAAGTTTATAATAATTTGATGGTTGATGTTAAGCCAACTAACGAAAAATTAGTTGAGCGTAGCAAA
CGAATCATTATGCAAGCAACAGATTGTACTTATGAAGAAGCCGAAGAAAAATTCAATGAAGCAAATCAAGATGTCAAACT
GGCGATTGTAATGCTTCTCACTGACTGTGCTGCAGAAGAAGGAAAGACAAAACTAGTTAAAGCAAATGGTTTTGTGAAAA
ATACTCTGAATTAA

Upstream 100 bases:

>100_bases
GAGAAAGTCAATGTCGTAGGCAAGATAATCGCTGAAGATAGACCACTCATTACTTTCATTGGTTCAGGACAAAAATTTAA
AATAGAAAAAGAGAAAAATA

Downstream 100 bases:

>100_bases
GAATTCACCCTTTTAAGGTAGAAAAAGGAGCAAAAATGGCGGAAGAAAAAATAGCTCGTATTGCAAGAGAGATTTATGAA
AATGTTGGCGGAACACAGAA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MIDLSTLTTERRNDETFNLDQMTVKEALVKMNNEDKKVAYAVEEALPNIEPVISSAIEAFNKGGRLIYMGAGTSGRLGVL
DAAECVPTFGVPATQVVGLIAGGDKAMTVAVEGAEDSLELGRQDLIDLNLSENDLVLGIAASGRTPYVIGALDYAKEIGA
KRASLSCNLNAEISKHAEFPIEVDCGPEFLTGSTRLKSGTAQKLILNMISTISMIGIGKVYNNLMVDVKPTNEKLVERSK
RIIMQATDCTYEEAEEKFNEANQDVKLAIVMLLTDCAAEEGKTKLVKANGFVKNTLN

Sequences:

>Translated_297_residues
MIDLSTLTTERRNDETFNLDQMTVKEALVKMNNEDKKVAYAVEEALPNIEPVISSAIEAFNKGGRLIYMGAGTSGRLGVL
DAAECVPTFGVPATQVVGLIAGGDKAMTVAVEGAEDSLELGRQDLIDLNLSENDLVLGIAASGRTPYVIGALDYAKEIGA
KRASLSCNLNAEISKHAEFPIEVDCGPEFLTGSTRLKSGTAQKLILNMISTISMIGIGKVYNNLMVDVKPTNEKLVERSK
RIIMQATDCTYEEAEEKFNEANQDVKLAIVMLLTDCAAEEGKTKLVKANGFVKNTLN
>Mature_297_residues
MIDLSTLTTERRNDETFNLDQMTVKEALVKMNNEDKKVAYAVEEALPNIEPVISSAIEAFNKGGRLIYMGAGTSGRLGVL
DAAECVPTFGVPATQVVGLIAGGDKAMTVAVEGAEDSLELGRQDLIDLNLSENDLVLGIAASGRTPYVIGALDYAKEIGA
KRASLSCNLNAEISKHAEFPIEVDCGPEFLTGSTRLKSGTAQKLILNMISTISMIGIGKVYNNLMVDVKPTNEKLVERSK
RIIMQATDCTYEEAEEKFNEANQDVKLAIVMLLTDCAAEEGKTKLVKANGFVKNTLN

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=296, Percent_Identity=48.9864864864865, Blast_Score=274, Evalue=6e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31998; Mature: 31998

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLSTLTTERRNDETFNLDQMTVKEALVKMNNEDKKVAYAVEEALPNIEPVISSAIEAF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
NKGGRLIYMGAGTSGRLGVLDAAECVPTFGVPATQVVGLIAGGDKAMTVAVEGAEDSLEL
CCCCEEEEEECCCCCCEECCCHHHHCCCCCCCHHHHEEEEECCCCEEEEEEECCCHHHHC
GRQDLIDLNLSENDLVLGIAASGRTPYVIGALDYAKEIGAKRASLSCNLNAEISKHAEFP
CCHHEEEECCCCCCEEEEEECCCCCCEEEEHHHHHHHHCCCCEEEEECCCCCHHHCCCCC
IEVDCGPEFLTGSTRLKSGTAQKLILNMISTISMIGIGKVYNNLMVDVKPTNEKLVERSK
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHH
RIIMQATDCTYEEAEEKFNEANQDVKLAIVMLLTDCAAEEGKTKLVKANGFVKNTLN
HEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCC
>Mature Secondary Structure
MIDLSTLTTERRNDETFNLDQMTVKEALVKMNNEDKKVAYAVEEALPNIEPVISSAIEAF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
NKGGRLIYMGAGTSGRLGVLDAAECVPTFGVPATQVVGLIAGGDKAMTVAVEGAEDSLEL
CCCCEEEEEECCCCCCEECCCHHHHCCCCCCCHHHHEEEEECCCCEEEEEEECCCHHHHC
GRQDLIDLNLSENDLVLGIAASGRTPYVIGALDYAKEIGAKRASLSCNLNAEISKHAEFP
CCHHEEEECCCCCCEEEEEECCCCCCEEEEHHHHHHHHCCCCEEEEECCCCCHHHCCCCC
IEVDCGPEFLTGSTRLKSGTAQKLILNMISTISMIGIGKVYNNLMVDVKPTNEKLVERSK
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHH
RIIMQATDCTYEEAEEKFNEANQDVKLAIVMLLTDCAAEEGKTKLVKANGFVKNTLN
HEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]