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The map label for this gene is rdrB [H]

Identifier: 125624002

GI number: 125624002

Start: 1139152

End: 1139913

Strand: Reverse

Name: rdrB [H]

Synonym: llmg_1172

Alternate gene names: 125624002

Gene position: 1139913-1139152 (Counterclockwise)

Preceding gene: 125624010

Following gene: 125624001

Centisome position: 45.07

GC content: 31.23

Gene sequence:

>762_bases
ATGTTATTAGAAGAAAGACTATCACAAATTAGCCAAATCGTTGATGAACAAGGCAGTGCCACAATTGACTTTTTAGCTCA
AAAACTTGAAGTTTCAAAAGATACAATTAGAAGAGATTTAATGAAATTAGAATCCAGAAAAAAATTGCATCGAGTTCATG
GTGGAGCAATTCCAATCGGTAAAGAGGCTGAAATTTTAAATTATGAAGAACGCTCAAATATTTCCAGTAATCTAAAGAAA
AAAATAGCAAGTAAAATAAAAAATCTCATTAAAGATCATAGCACTCTTATTTTTGATTCATCAACAACCGTCGAAGCTGC
TATTAAACAACTTGATAACCTCTCTATCTCAACCATCACAAACTCCCTTACCAATGCAATATTACTTTCAAAGTATGAGA
AGGCAACCGTACAACTTCTTCCAGGAAAATTAAACAAGAATCAACTATTCTTGTATGGCGCGGAGACTGTTGAAAAACTC
TCTCAATACCAAGTGGATTTTACAATCTTAGGCGTTTTTGCTCTTTCTAATGATGGCTTATTTATTCATACGCAAGAGGA
AGGCATTGTCAAAAGAAAAATGATTCAACAAGGTAAGCAAGTCATAGCACTAGCAGATCATACTAAACTTAATAAAGAAG
GATTCTTTAAAATTTGTGATTTAAAAGAAATAGACTACCTCATTACTGATGAAAAAATTGAAGGTGAATTGATGAAAAAT
TTAAATGATAATAATGTGAAAGTAGTGACTATAAATGAATAA

Upstream 100 bases:

>100_bases
GCATCGTTTTGCAAGTTGCATTTATTTGTAATTAAATAAATGCATTATGTTGCATAATCAAATAGTCTATGATATGATGA
TAAGTAAGAAAGGAGAGCAA

Downstream 100 bases:

>100_bases
AGAAATTGTTTACGAAAGAATAAACGAACCAAAGCTCTTTAATAATGTTCCACCAGTTACACTAACGGACAAAACATTAG
AGGAACGAAAAGAAAAGCTT

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLLEERLSQISQIVDEQGSATIDFLAQKLEVSKDTIRRDLMKLESRKKLHRVHGGAIPIGKEAEILNYEERSNISSNLKK
KIASKIKNLIKDHSTLIFDSSTTVEAAIKQLDNLSISTITNSLTNAILLSKYEKATVQLLPGKLNKNQLFLYGAETVEKL
SQYQVDFTILGVFALSNDGLFIHTQEEGIVKRKMIQQGKQVIALADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMKN
LNDNNVKVVTINE

Sequences:

>Translated_253_residues
MLLEERLSQISQIVDEQGSATIDFLAQKLEVSKDTIRRDLMKLESRKKLHRVHGGAIPIGKEAEILNYEERSNISSNLKK
KIASKIKNLIKDHSTLIFDSSTTVEAAIKQLDNLSISTITNSLTNAILLSKYEKATVQLLPGKLNKNQLFLYGAETVEKL
SQYQVDFTILGVFALSNDGLFIHTQEEGIVKRKMIQQGKQVIALADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMKN
LNDNNVKVVTINE
>Mature_253_residues
MLLEERLSQISQIVDEQGSATIDFLAQKLEVSKDTIRRDLMKLESRKKLHRVHGGAIPIGKEAEILNYEERSNISSNLKK
KIASKIKNLIKDHSTLIFDSSTTVEAAIKQLDNLSISTITNSLTNAILLSKYEKATVQLLPGKLNKNQLFLYGAETVEKL
SQYQVDFTILGVFALSNDGLFIHTQEEGIVKRKMIQQGKQVIALADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMKN
LNDNNVKVVTINE

Specific function: Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788069, Length=252, Percent_Identity=32.5396825396825, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082344, Length=254, Percent_Identity=29.1338582677165, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=28.8537549407115, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789829, Length=246, Percent_Identity=29.2682926829268, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789059, Length=255, Percent_Identity=25.0980392156863, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI226510968, Length=235, Percent_Identity=25.1063829787234, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789170, Length=221, Percent_Identity=26.6968325791855, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790635, Length=237, Percent_Identity=22.7848101265823, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28560; Mature: 28560

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEERLSQISQIVDEQGSATIDFLAQKLEVSKDTIRRDLMKLESRKKLHRVHGGAIPIG
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KEAEILNYEERSNISSNLKKKIASKIKNLIKDHSTLIFDSSTTVEAAIKQLDNLSISTIT
CCCHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCHHHHHH
NSLTNAILLSKYEKATVQLLPGKLNKNQLFLYGAETVEKLSQYQVDFTILGVFALSNDGL
HHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEEEEECCCCE
FIHTQEEGIVKRKMIQQGKQVIALADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMKN
EEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCEEEECCHHHHHHHHC
LNDNNVKVVTINE
CCCCCEEEEEECC
>Mature Secondary Structure
MLLEERLSQISQIVDEQGSATIDFLAQKLEVSKDTIRRDLMKLESRKKLHRVHGGAIPIG
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KEAEILNYEERSNISSNLKKKIASKIKNLIKDHSTLIFDSSTTVEAAIKQLDNLSISTIT
CCCHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCHHHHHH
NSLTNAILLSKYEKATVQLLPGKLNKNQLFLYGAETVEKLSQYQVDFTILGVFALSNDGL
HHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEEEEECCCCE
FIHTQEEGIVKRKMIQQGKQVIALADHTKLNKEGFFKICDLKEIDYLITDEKIEGELMKN
EEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCEEEECCHHHHHHHHC
LNDNNVKVVTINE
CCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]