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The map label for this gene is glpD [H]

Identifier: 125623929

GI number: 125623929

Start: 1057090

End: 1058667

Strand: Reverse

Name: glpD [H]

Synonym: llmg_1098

Alternate gene names: 125623929

Gene position: 1058667-1057090 (Counterclockwise)

Preceding gene: 125623930

Following gene: 125623928

Centisome position: 41.85

GC content: 40.05

Gene sequence:

>1578_bases
ATGTCTATCTCTCGTCAAAAAAATATTGAATATTTAAAAGCAAATCCCGATGATTGGGACTTCATTATTATCGGTGGTGG
AGCAACCGGACTTGGAGTTGCGGTTGACGCCGCATCACGCGGTTATAAAACAGTTCTAGTTGAACAAAGTGACTTTGCAA
AATCAACTTCAAGCCGCTCGACAAAACTTGTTCACGGTGGCGTTCGCTACCTTGCTCAAGGAGATGTCAGCCTTGTTCGT
GAAGCATTACATGAAAGAGGTCGCCTTGCTCGCAACGCTCCCCATCTTGTAAAAAATCAAAAATTTATCATTGCTAATTA
CAAAGCTTGGGAGCAACCATTTTATAGCATCGGAATGAAAATGTATGATGCTTTGGCAGGTAAATTGAATATTGGAAAAT
CAAAAATTTATTCTAAGAAAAAAGTTGCTGAAGCAATTCCTCAAATCAAACATGAACATCTCGTCGGAGGAGTCATGTAT
TATGACGGACAATTCGATGATGCTAGAATGGCTATCAACCTTATGCAAACTGCCACTGAACAAGGTGCGCTACTAGTTAA
TTATGTCAAAGTGACTGAGCTTGTTAAAACGGACTCAAAAGTATCTTCTGTTAAACTTCATGATGAACTTTCTGGCGAAT
CATTTGAACTTCACGGAAAAGCCATCATCAACGCTACAGGAATCTTTGTTGACCAAATTATGTCAATGGATACCAAAGAA
CACAAACCCTCTGTTCGTCCTTCACAAGGCGTCCACCTCATTGTTGACGGCTCATTTCTCGGTGGTCAAGATGCCATCAT
GGTTCCAAAAACTTCTGACGGGCGTGTCTTGTTCTGTGTCCCTTGGCATAATAAAGTAATCTTAGGAACGACAGATACAC
CTCTTACAGAATTCGTTTTAGAACCTCGACCACTTGAAGAAGAAATTGATTTCATCTTAGAAACTGCTGGTCAATATTTA
GAAAAGAAACCCGAACGTAAAGATGTTTTAACTGCTTATGCTGGTTTACGTCCACTTGCTGCTCCCAAAGAAGGCGATGG
CGAAAAAACGAAAGAAATTTCAAGAAGTCATAAACTCTTCACCTCTGAATCAGGACTGGTCACAATTACTGGGGGAAAAT
GGACAACTTATCGCCAAATGGCCGAAGAAACTGTTGATTTAGCAATCAAAACCTCTAAACTTCCTGAAAAAAAATGTATC
ACCAGAACATTGAAAATACATGGGGCCAAAGAAACAACTGAAAGAGAACGTCAAAACTGGCTCTATGTTTACGGTTCTGA
TAAAGGAAAGATTTTAGCTCTCCAAAATGAAGACTCTTCTTTAGCCTTACCTCTTCACCCAAAATACGAATTTACAGGTT
CTGAAGTCATCTGGGCTGTCCGTGAAGAAATGGCTCAAACTCTAGATGATGTTCTCGCTCGTCGGATTCGTGCACTTTTC
CTTGATGCAAGAATTGCCAAAGAAATGGCTCCCAAAGTCGCCCAACTGATGTCGAAAGAAATGGGGAAAGATGAAGCATG
GGAAAAAGAACAAGTTGAGAGCTTCCTTACTTTAGCTGATGGTTATATTTTAAAATAA

Upstream 100 bases:

>100_bases
TATTCTGGCTGGAAGAAAGCCGTAGAGGCAACAAGATCTTTTGAATAAATCATATTAAAAGTATCATAAATGTATCGCTT
ATTAGAATTGGAGTAACAAG

Downstream 100 bases:

>100_bases
TTTTAGGAGAATATCTATATGAACTCTACTTTTGTTCAATTCCTTGGAGAATTTATCGGGACATTTATCCTGATTCTACT
TGGTAACGGGATTGTCTGTG

Product: GlpD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MSISRQKNIEYLKANPDDWDFIIIGGGATGLGVAVDAASRGYKTVLVEQSDFAKSTSSRSTKLVHGGVRYLAQGDVSLVR
EALHERGRLARNAPHLVKNQKFIIANYKAWEQPFYSIGMKMYDALAGKLNIGKSKIYSKKKVAEAIPQIKHEHLVGGVMY
YDGQFDDARMAINLMQTATEQGALLVNYVKVTELVKTDSKVSSVKLHDELSGESFELHGKAIINATGIFVDQIMSMDTKE
HKPSVRPSQGVHLIVDGSFLGGQDAIMVPKTSDGRVLFCVPWHNKVILGTTDTPLTEFVLEPRPLEEEIDFILETAGQYL
EKKPERKDVLTAYAGLRPLAAPKEGDGEKTKEISRSHKLFTSESGLVTITGGKWTTYRQMAEETVDLAIKTSKLPEKKCI
TRTLKIHGAKETTERERQNWLYVYGSDKGKILALQNEDSSLALPLHPKYEFTGSEVIWAVREEMAQTLDDVLARRIRALF
LDARIAKEMAPKVAQLMSKEMGKDEAWEKEQVESFLTLADGYILK

Sequences:

>Translated_525_residues
MSISRQKNIEYLKANPDDWDFIIIGGGATGLGVAVDAASRGYKTVLVEQSDFAKSTSSRSTKLVHGGVRYLAQGDVSLVR
EALHERGRLARNAPHLVKNQKFIIANYKAWEQPFYSIGMKMYDALAGKLNIGKSKIYSKKKVAEAIPQIKHEHLVGGVMY
YDGQFDDARMAINLMQTATEQGALLVNYVKVTELVKTDSKVSSVKLHDELSGESFELHGKAIINATGIFVDQIMSMDTKE
HKPSVRPSQGVHLIVDGSFLGGQDAIMVPKTSDGRVLFCVPWHNKVILGTTDTPLTEFVLEPRPLEEEIDFILETAGQYL
EKKPERKDVLTAYAGLRPLAAPKEGDGEKTKEISRSHKLFTSESGLVTITGGKWTTYRQMAEETVDLAIKTSKLPEKKCI
TRTLKIHGAKETTERERQNWLYVYGSDKGKILALQNEDSSLALPLHPKYEFTGSEVIWAVREEMAQTLDDVLARRIRALF
LDARIAKEMAPKVAQLMSKEMGKDEAWEKEQVESFLTLADGYILK
>Mature_524_residues
SISRQKNIEYLKANPDDWDFIIIGGGATGLGVAVDAASRGYKTVLVEQSDFAKSTSSRSTKLVHGGVRYLAQGDVSLVRE
ALHERGRLARNAPHLVKNQKFIIANYKAWEQPFYSIGMKMYDALAGKLNIGKSKIYSKKKVAEAIPQIKHEHLVGGVMYY
DGQFDDARMAINLMQTATEQGALLVNYVKVTELVKTDSKVSSVKLHDELSGESFELHGKAIINATGIFVDQIMSMDTKEH
KPSVRPSQGVHLIVDGSFLGGQDAIMVPKTSDGRVLFCVPWHNKVILGTTDTPLTEFVLEPRPLEEEIDFILETAGQYLE
KKPERKDVLTAYAGLRPLAAPKEGDGEKTKEISRSHKLFTSESGLVTITGGKWTTYRQMAEETVDLAIKTSKLPEKKCIT
RTLKIHGAKETTERERQNWLYVYGSDKGKILALQNEDSSLALPLHPKYEFTGSEVIWAVREEMAQTLDDVLARRIRALFL
DARIAKEMAPKVAQLMSKEMGKDEAWEKEQVESFLTLADGYILK

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=556, Percent_Identity=39.568345323741, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI285002231, Length=556, Percent_Identity=39.568345323741, Blast_Score=375, Evalue=1e-104,
Organism=Escherichia coli, GI2367226, Length=491, Percent_Identity=27.0875763747454, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788574, Length=501, Percent_Identity=27.7445109780439, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17509253, Length=534, Percent_Identity=39.5131086142322, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI115534726, Length=530, Percent_Identity=37.3584905660377, Blast_Score=311, Evalue=5e-85,
Organism=Saccharomyces cerevisiae, GI6322036, Length=564, Percent_Identity=35.6382978723404, Blast_Score=318, Evalue=2e-87,
Organism=Drosophila melanogaster, GI161077125, Length=531, Percent_Identity=39.924670433145, Blast_Score=351, Evalue=8e-97,
Organism=Drosophila melanogaster, GI24653942, Length=531, Percent_Identity=39.924670433145, Blast_Score=351, Evalue=8e-97,
Organism=Drosophila melanogaster, GI24653944, Length=531, Percent_Identity=39.924670433145, Blast_Score=351, Evalue=8e-97,
Organism=Drosophila melanogaster, GI20130025, Length=531, Percent_Identity=39.924670433145, Blast_Score=351, Evalue=8e-97,
Organism=Drosophila melanogaster, GI19921278, Length=540, Percent_Identity=35, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24586295, Length=528, Percent_Identity=32.0075757575758, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI45550977, Length=391, Percent_Identity=33.2480818414322, Blast_Score=197, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 58581; Mature: 58450

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISRQKNIEYLKANPDDWDFIIIGGGATGLGVAVDAASRGYKTVLVEQSDFAKSTSSRS
CCCCCCCCCEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEECCHHHCCCCCCC
TKLVHGGVRYLAQGDVSLVREALHERGRLARNAPHLVKNQKFIIANYKAWEQPFYSIGMK
EEEEECCHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCHHHHCHHHHHHHH
MYDALAGKLNIGKSKIYSKKKVAEAIPQIKHEHLVGGVMYYDGQFDDARMAINLMQTATE
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCC
QGALLVNYVKVTELVKTDSKVSSVKLHDELSGESFELHGKAIINATGIFVDQIMSMDTKE
CCCEEEEHHHHHHHHHCCCCHHEEEEHHCCCCCEEEECCEEEEEEHHHHHHHHHHCCCHH
HKPSVRPSQGVHLIVDGSFLGGQDAIMVPKTSDGRVLFCVPWHNKVILGTTDTPLTEFVL
CCCCCCCCCCEEEEEECCEECCCCEEEEECCCCCEEEEEEECCCEEEEECCCCCHHHHHC
EPRPLEEEIDFILETAGQYLEKKPERKDVLTAYAGLRPLAAPKEGDGEKTKEISRSHKLF
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCEE
TSESGLVTITGGKWTTYRQMAEETVDLAIKTSKLPEKKCITRTLKIHGAKETTERERQNW
ECCCCEEEEECCCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHEECCCCHHHHHHHCCE
LYVYGSDKGKILALQNEDSSLALPLHPKYEFTGSEVIWAVREEMAQTLDDVLARRIRALF
EEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LDARIAKEMAPKVAQLMSKEMGKDEAWEKEQVESFLTLADGYILK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEC
>Mature Secondary Structure 
SISRQKNIEYLKANPDDWDFIIIGGGATGLGVAVDAASRGYKTVLVEQSDFAKSTSSRS
CCCCCCCCEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEECCHHHCCCCCCC
TKLVHGGVRYLAQGDVSLVREALHERGRLARNAPHLVKNQKFIIANYKAWEQPFYSIGMK
EEEEECCHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHCCCEEEEECCHHHHCHHHHHHHH
MYDALAGKLNIGKSKIYSKKKVAEAIPQIKHEHLVGGVMYYDGQFDDARMAINLMQTATE
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHCC
QGALLVNYVKVTELVKTDSKVSSVKLHDELSGESFELHGKAIINATGIFVDQIMSMDTKE
CCCEEEEHHHHHHHHHCCCCHHEEEEHHCCCCCEEEECCEEEEEEHHHHHHHHHHCCCHH
HKPSVRPSQGVHLIVDGSFLGGQDAIMVPKTSDGRVLFCVPWHNKVILGTTDTPLTEFVL
CCCCCCCCCCEEEEEECCEECCCCEEEEECCCCCEEEEEEECCCEEEEECCCCCHHHHHC
EPRPLEEEIDFILETAGQYLEKKPERKDVLTAYAGLRPLAAPKEGDGEKTKEISRSHKLF
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCEE
TSESGLVTITGGKWTTYRQMAEETVDLAIKTSKLPEKKCITRTLKIHGAKETTERERQNW
ECCCCEEEEECCCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHEECCCCHHHHHHHCCE
LYVYGSDKGKILALQNEDSSLALPLHPKYEFTGSEVIWAVREEMAQTLDDVLARRIRALF
EEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LDARIAKEMAPKVAQLMSKEMGKDEAWEKEQVESFLTLADGYILK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]