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The map label for this gene is coaA [H]

Identifier: 125623889

GI number: 125623889

Start: 1019146

End: 1020066

Strand: Reverse

Name: coaA [H]

Synonym: llmg_1058

Alternate gene names: 125623889

Gene position: 1020066-1019146 (Counterclockwise)

Preceding gene: 125623897

Following gene: 125623882

Centisome position: 40.33

GC content: 33.66

Gene sequence:

>921_bases
ATGAATGAATTCATTAATTTTGACGAAATTAGTCGTGAAACTTGGCAAAATCTTTACAATACTTCTATCGCCCCATTAAC
ACATGATGAATTAGAATCAATTCGCTCACTCAATGACGAAATCAGCTTGCAAGACGTGGAGGACGTCTATCTACCTCTGA
TTCATCTTCTTCGTTTATATAAAAAAAATTTAGAAGATATGAGCTATTCTAAAGGACTTTTTTTACAAAAAATCGTTAAA
ACTCCTCCTTTGATTATTGGAATTTCGGGGTCAGTAGCCGTTGGTAAATCAACCACAGCAAGACTCCTTCAACTTCTCCT
CTCACGTGCATTTCCAAAATTAACTGTAGATTTAGTCACAACTGACGGATTTTTATACACAACTGATGATTTAAAAAATA
TGGGAATTCTCGACCGTAAAGGTTTTCCAGAAAGCTACGATATGGAAAAACTGACAAGTTTTCTTTATCATGTCAAAAAT
GGCGAAAGATTTGAAGTTCCGATTTATTCTCATGAAACTTATGATATTTTACCTAATCAAAGTCAAATTATTGACAGTCC
CGATATTTTAATTGTTGAGGGGATTAATGTCTTACAAAATCCGCAAAATCAACTCCTTTACATCAGCGATTTTTATGATT
TTTCAATCTATGTTGACGCTGACGAAAAACTCATTGAAAAATGGTACCTTGAACGCTTTGATAGTCTTTTAAAATTGGCA
AAGTATGACCAAACAAATTTCTATCATCAATTTACAAAAATGCCTGAGGACAAAGTACTAAATTTAGCCCGTGAAACATG
GGCACGTGTCAATCGTGTCAATCTCCGAGAATATATTGAACCCACAAGAAATCGGGCAGAAATCATTCTCCACAAGGCAG
AAAATCATCACATTGATAAAATATATCTAAAAAAATTCTAA

Upstream 100 bases:

>100_bases
GACCACTAAGCTCAAAAGTTGTCAGTAACATATTTAATACGCTTACAGATTTATTAGTTTTTTTACCTCGATAGACCAAA
AATATGATAAAATATTTGTC

Downstream 100 bases:

>100_bases
AAAAAATTACTGACAAATCTGTCAGTAATTTTTTATTTATTTATTTTACTGACAGAACCGTCAGGCAAAATTAGAAATAA
TCTGCTGTATCATCATTTGG

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNEFINFDEISRETWQNLYNTSIAPLTHDELESIRSLNDEISLQDVEDVYLPLIHLLRLYKKNLEDMSYSKGLFLQKIVK
TPPLIIGISGSVAVGKSTTARLLQLLLSRAFPKLTVDLVTTDGFLYTTDDLKNMGILDRKGFPESYDMEKLTSFLYHVKN
GERFEVPIYSHETYDILPNQSQIIDSPDILIVEGINVLQNPQNQLLYISDFYDFSIYVDADEKLIEKWYLERFDSLLKLA
KYDQTNFYHQFTKMPEDKVLNLARETWARVNRVNLREYIEPTRNRAEIILHKAENHHIDKIYLKKF

Sequences:

>Translated_306_residues
MNEFINFDEISRETWQNLYNTSIAPLTHDELESIRSLNDEISLQDVEDVYLPLIHLLRLYKKNLEDMSYSKGLFLQKIVK
TPPLIIGISGSVAVGKSTTARLLQLLLSRAFPKLTVDLVTTDGFLYTTDDLKNMGILDRKGFPESYDMEKLTSFLYHVKN
GERFEVPIYSHETYDILPNQSQIIDSPDILIVEGINVLQNPQNQLLYISDFYDFSIYVDADEKLIEKWYLERFDSLLKLA
KYDQTNFYHQFTKMPEDKVLNLARETWARVNRVNLREYIEPTRNRAEIILHKAENHHIDKIYLKKF
>Mature_306_residues
MNEFINFDEISRETWQNLYNTSIAPLTHDELESIRSLNDEISLQDVEDVYLPLIHLLRLYKKNLEDMSYSKGLFLQKIVK
TPPLIIGISGSVAVGKSTTARLLQLLLSRAFPKLTVDLVTTDGFLYTTDDLKNMGILDRKGFPESYDMEKLTSFLYHVKN
GERFEVPIYSHETYDILPNQSQIIDSPDILIVEGINVLQNPQNQLLYISDFYDFSIYVDADEKLIEKWYLERFDSLLKLA
KYDQTNFYHQFTKMPEDKVLNLARETWARVNRVNLREYIEPTRNRAEIILHKAENHHIDKIYLKKF

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=312, Percent_Identity=40.7051282051282, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35955; Mature: 35955

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFINFDEISRETWQNLYNTSIAPLTHDELESIRSLNDEISLQDVEDVYLPLIHLLRLY
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
KKNLEDMSYSKGLFLQKIVKTPPLIIGISGSVAVGKSTTARLLQLLLSRAFPKLTVDLVT
HHHHHHCCHHCCHHHHHHHCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCEEEEEEE
TDGFLYTTDDLKNMGILDRKGFPESYDMEKLTSFLYHVKNGERFEVPIYSHETYDILPNQ
CCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCC
SQIIDSPDILIVEGINVLQNPQNQLLYISDFYDFSIYVDADEKLIEKWYLERFDSLLKLA
HHHCCCCCEEEEECCHHHHCCCCCEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
KYDQTNFYHQFTKMPEDKVLNLARETWARVNRVNLREYIEPTRNRAEIILHKAENHHIDK
HCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCCCE
IYLKKF
EEEECC
>Mature Secondary Structure
MNEFINFDEISRETWQNLYNTSIAPLTHDELESIRSLNDEISLQDVEDVYLPLIHLLRLY
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
KKNLEDMSYSKGLFLQKIVKTPPLIIGISGSVAVGKSTTARLLQLLLSRAFPKLTVDLVT
HHHHHHCCHHCCHHHHHHHCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCEEEEEEE
TDGFLYTTDDLKNMGILDRKGFPESYDMEKLTSFLYHVKNGERFEVPIYSHETYDILPNQ
CCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCC
SQIIDSPDILIVEGINVLQNPQNQLLYISDFYDFSIYVDADEKLIEKWYLERFDSLLKLA
HHHCCCCCEEEEECCHHHHCCCCCEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHH
KYDQTNFYHQFTKMPEDKVLNLARETWARVNRVNLREYIEPTRNRAEIILHKAENHHIDK
HCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCCCE
IYLKKF
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]