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The map label for this gene is bglH [H]

Identifier: 125623877

GI number: 125623877

Start: 1008557

End: 1009993

Strand: Direct

Name: bglH [H]

Synonym: llmg_1046

Alternate gene names: 125623877

Gene position: 1008557-1009993 (Clockwise)

Preceding gene: 125623876

Following gene: 125623878

Centisome position: 39.87

GC content: 35.77

Gene sequence:

>1437_bases
ATGACATTTAAAACAGACTTTTTATGGGGTGGAGCAACGGCAGCAAACCAATTAGAAGGTGCTTATGATATAGATGGTAA
AGGGCTCTCAGTAGCAGATGCAATGCCAGGAGGTAAAGAAAGATTGGCAATTCTTGCAAGTCCGGAATTTGATTGGACGA
TTGATACTGAACATTTTACTTATCCAAATCATGATGGAATTGATCATTATCATCATTTTAAAGAAGACATTGCATTATTT
GCGGAAATGGGTTTTAAAGCGTATCGTTTTTCAGTAGCTTGGTCAAGAATTTTTCCAAAGGGAGATGAAACAACTCCCAA
TGAAAAAGGTTTGCTTTTTTATGATCAACTGATTGATGAGTGTTTGAAATATAGAATTGAACCAGTGATTACAATTTCTC
ACTATGAAATGCCACTTAATTTGGCTAAATCATATGGAGGATGGAAAAATCGTGAACTTATCGAATTTTATGTGCGGTTT
GCAAAAGTCCTTTTAGAACGCTATCAAGACAAAGTAAAATATTGGATGACGTTTAATGAAATTAACTCGGCGACTTTCTT
TTCAGGCTTAAGTCAAGGACTTGTTCCATCTAATGGTGGAGATGATAAAACTAATGTATTTAAAGCTTGGCATAATCAGT
TCGTTGCAAGTGCTCAAGCAGTTAAATTTGGTCATGATTTGAATAAAAATTTGAAACTTGGTTGCATGAGCATTTATTCA
ACAACTTATTCCTTTGATGCTAATCCAGTCAATCAATTGGCGACACAAGAAAGTATTCAAGAATTTAATTATTTTTGTAA
TGATGTCCAAGTTCGCGGAGCCTACCCTGCGTTTACAAATAGACTTCATCGGAAACATGGAGTAAATTCAGAAGTCCTTG
AAATTTCTGAAGAAGATCTTAAGATAATCGCAGAAGGAACAGTTGACTATATAGGGTTTAGTTATTACATGTCGACGGTT
GAATCAAAAACGGGAGAAGGCGTCCAAGCTTCAGGGAATATGGTTCTTGGCGGAGTAAAAAATCCTTTCTTAAAAGAAAG
TGAATGGGGTTGGGCAATTGATCCTGATGGTCTTCGGTATGCTCTCAATGATTTGTACGGACGCTATCAAATTCCTCTCT
TCATTGTTGAAAATGGTTTGGGGGCAATTGATAAAGTTGAAGAAGACGGAACTATTCAAGATGATTATCGGATTGACTAT
CTCAAAAAACATATTCAATCAATGAGTGAAGCAGTTGAAGATGGTGTTGAACTAATGGGTTATACACCTTGGGGCTGTAT
TGACTTAGTTTCTGCATCAACAGGGGAGATGAGTAAACGTTATGGTTTTATCTACGTTGACTTAGATGATAGCGGAAATG
GAACGAATAAAAGATTTAAGAAAAAATCGTTCGATTGGTATAAACAAGTAATTGATTCTAACGGTACGAATTTATAA

Upstream 100 bases:

>100_bases
TACTAACTGCAGTTAATGCACAAACAACTGAATTAGTGGCAAATCCAGTTTAAAATAGCATTGATGAAAAACTTTAAAAA
TTAGATAGGAAAATTATAAA

Downstream 100 bases:

>100_bases
AAAAATAGCTTCTCATATTTAGAAGCTATTTTTAGTCCAGCTCTTTTGAAAGTGGGGCGATGTGGTATAGATTGAAAAAT
AATAAATAAAGCGCTATAAT

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MTFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDTEHFTYPNHDGIDHYHHFKEDIALF
AEMGFKAYRFSVAWSRIFPKGDETTPNEKGLLFYDQLIDECLKYRIEPVITISHYEMPLNLAKSYGGWKNRELIEFYVRF
AKVLLERYQDKVKYWMTFNEINSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKNLKLGCMSIYS
TTYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNSEVLEISEEDLKIIAEGTVDYIGFSYYMSTV
ESKTGEGVQASGNMVLGGVKNPFLKESEWGWAIDPDGLRYALNDLYGRYQIPLFIVENGLGAIDKVEEDGTIQDDYRIDY
LKKHIQSMSEAVEDGVELMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDSGNGTNKRFKKKSFDWYKQVIDSNGTNL

Sequences:

>Translated_478_residues
MTFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDTEHFTYPNHDGIDHYHHFKEDIALF
AEMGFKAYRFSVAWSRIFPKGDETTPNEKGLLFYDQLIDECLKYRIEPVITISHYEMPLNLAKSYGGWKNRELIEFYVRF
AKVLLERYQDKVKYWMTFNEINSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKNLKLGCMSIYS
TTYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNSEVLEISEEDLKIIAEGTVDYIGFSYYMSTV
ESKTGEGVQASGNMVLGGVKNPFLKESEWGWAIDPDGLRYALNDLYGRYQIPLFIVENGLGAIDKVEEDGTIQDDYRIDY
LKKHIQSMSEAVEDGVELMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDSGNGTNKRFKKKSFDWYKQVIDSNGTNL
>Mature_477_residues
TFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDTEHFTYPNHDGIDHYHHFKEDIALFA
EMGFKAYRFSVAWSRIFPKGDETTPNEKGLLFYDQLIDECLKYRIEPVITISHYEMPLNLAKSYGGWKNRELIEFYVRFA
KVLLERYQDKVKYWMTFNEINSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKNLKLGCMSIYST
TYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNSEVLEISEEDLKIIAEGTVDYIGFSYYMSTVE
SKTGEGVQASGNMVLGGVKNPFLKESEWGWAIDPDGLRYALNDLYGRYQIPLFIVENGLGAIDKVEEDGTIQDDYRIDYL
KKHIQSMSEAVEDGVELMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDSGNGTNKRFKKKSFDWYKQVIDSNGTNL

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=493, Percent_Identity=30.4259634888438, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI110681710, Length=495, Percent_Identity=28.8888888888889, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI13273313, Length=496, Percent_Identity=28.0241935483871, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI28376633, Length=500, Percent_Identity=26.2, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI24497614, Length=490, Percent_Identity=26.3265306122449, Blast_Score=141, Evalue=2e-33,
Organism=Escherichia coli, GI2367174, Length=485, Percent_Identity=52.7835051546392, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1789070, Length=477, Percent_Identity=49.0566037735849, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI2367270, Length=481, Percent_Identity=49.6881496881497, Blast_Score=451, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17552856, Length=494, Percent_Identity=30.3643724696356, Blast_Score=178, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17539390, Length=493, Percent_Identity=27.1805273833671, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI21356577, Length=487, Percent_Identity=27.9260780287474, Blast_Score=160, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54239; Mature: 54108

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDTEHFT
CCEECCEEECCCCHHHHCCCCEECCCCCCCHHCCCCCCCCEEEEEECCCCCEEECCCCCC
YPNHDGIDHYHHFKEDIALFAEMGFKAYRFSVAWSRIFPKGDETTPNEKGLLFYDQLIDE
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCCCCCCEEHHHHHHHH
CLKYRIEPVITISHYEMPLNLAKSYGGWKNRELIEFYVRFAKVLLERYQDKVKYWMTFNE
HHHHCCCEEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHH
INSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKNLKLGCMSIYS
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHH
TTYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNSEVLEISEEDL
EEEECCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCHHHHHCCCCCE
KIIAEGTVDYIGFSYYMSTVESKTGEGVQASGNMVLGGVKNPFLKESEWGWAIDPDGLRY
EEEECCCHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHH
ALNDLYGRYQIPLFIVENGLGAIDKVEEDGTIQDDYRIDYLKKHIQSMSEAVEDGVELMG
HHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHEEC
YTPWGCIDLVSASTGEMSKRYGFIYVDLDDSGNGTNKRFKKKSFDWYKQVIDSNGTNL
CCCCCHHHHHCCCCCCHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TFKTDFLWGGATAANQLEGAYDIDGKGLSVADAMPGGKERLAILASPEFDWTIDTEHFT
CEECCEEECCCCHHHHCCCCEECCCCCCCHHCCCCCCCCEEEEEECCCCCEEECCCCCC
YPNHDGIDHYHHFKEDIALFAEMGFKAYRFSVAWSRIFPKGDETTPNEKGLLFYDQLIDE
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCCCCCCEEHHHHHHHH
CLKYRIEPVITISHYEMPLNLAKSYGGWKNRELIEFYVRFAKVLLERYQDKVKYWMTFNE
HHHHCCCEEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHH
INSATFFSGLSQGLVPSNGGDDKTNVFKAWHNQFVASAQAVKFGHDLNKNLKLGCMSIYS
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHH
TTYSFDANPVNQLATQESIQEFNYFCNDVQVRGAYPAFTNRLHRKHGVNSEVLEISEEDL
EEEECCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCHHHHHCCCCCE
KIIAEGTVDYIGFSYYMSTVESKTGEGVQASGNMVLGGVKNPFLKESEWGWAIDPDGLRY
EEEECCCHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHH
ALNDLYGRYQIPLFIVENGLGAIDKVEEDGTIQDDYRIDYLKKHIQSMSEAVEDGVELMG
HHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHEEC
YTPWGCIDLVSASTGEMSKRYGFIYVDLDDSGNGTNKRFKKKSFDWYKQVIDSNGTNL
CCCCCHHHHHCCCCCCHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]