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The map label for this gene is trpD [H]

Identifier: 125623867

GI number: 125623867

Start: 996817

End: 997824

Strand: Direct

Name: trpD [H]

Synonym: llmg_1032

Alternate gene names: 125623867

Gene position: 996817-997824 (Clockwise)

Preceding gene: 125623866

Following gene: 125623868

Centisome position: 39.41

GC content: 43.75

Gene sequence:

>1008_bases
ATGAAAAATGAACTTGAAAAAGTCATGGCAGGTCGTGATATGACTGAAAATGAAATGAATATGCTAGCCAATTCAATTAT
TCAAGGCGAATTGAGCGACGTTCAAATTGCTAGTTTTCTAGTAGCTCTCAAAATGAAAGGCGAATCCGCCAGCGAATTAA
CAGGACTTGCACGGGCTTTGCAAAAAGCAGCCATCAGTATTCCGACAAACTTGACCAATGCCATGGACAATTGCGGAACA
GGCGGCGACCGTTCATTCAGCTTCAATATTTCAACCACAGCGGCCTTTGTTTTAGCAGCTGGTGGCGTCAACATGGCAAA
ACACGGCAACCGCTCAATTACCAGTAAATCTGGCTCGGCTGATGTTCTTGAAGCTTTGGGAATCAACCTTTATCTCCCCG
CAGAAAAATTGGCTCAAGTGTTTGATAAAGTTGGTCTAGTTTTCCTTTTTGCTCAAAATTTGCATCCAGCCATGAAATAC
TTCACACCAGTGCGCAGACAGCTTGAAATTCCAACCATCATGAACCTGACAGGCCCTTTGATTAATCCGATTCCACTTGA
TACGCAACTCCTTGGAACGTCACGTCCTGACCTGCTCGAGCTGACGGCAAATGTCCTCAAAGGCTTGGGACGTAAGCGAG
CATTGGTTATTACAGGCGAAGGAGGGATGGATGAGGCAACACCATTTGGTCTCAATCATTATGCCCTTTTGGAAAATGGT
GAAGTGACTTTGCACAAGTTTAGAGCTGCCGATGTTGGCATGTCAGAAGTCGCGCTCAATGATATTCGCGGTGGTGAAGC
GCCAGAAAATGCCGAGATTTTGAAAAATGTTCTGGAAAATTGTTCGTCAGCATTTTTAGAAACAACTGTTTTAAATGCAG
GATTGGGATTCTATGCCAATGGCAAGGTTGATTCCATCAAATCAGGAATTGAACTTGCAAGAGAAGTCATAGCGCAAGGC
GCAGCACTTGAAAAATTGCATGAATTACAAGCAGAACAAATTGGTTAA

Upstream 100 bases:

>100_bases
TACGGTCTGCAATTTCATCCAGAATCAATTGGGACGCTGGATGGCATGATCATGATTGAAAATTTTGTCAATCAAGTAAA
AGCAATAAAGGAGTAATCAA

Downstream 100 bases:

>100_bases
AAATTTACTGACATAAAAAATATTTATTGAAATTGGATTTGATTTGGATAATAATATATTTGGATTTAGAAGAAGTATTG
AAATTGAATATGCTGACGAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKNELEKVMAGRDMTENEMNMLANSIIQGELSDVQIASFLVALKMKGESASELTGLARALQKAAISIPTNLTNAMDNCGT
GGDRSFSFNISTTAAFVLAAGGVNMAKHGNRSITSKSGSADVLEALGINLYLPAEKLAQVFDKVGLVFLFAQNLHPAMKY
FTPVRRQLEIPTIMNLTGPLINPIPLDTQLLGTSRPDLLELTANVLKGLGRKRALVITGEGGMDEATPFGLNHYALLENG
EVTLHKFRAADVGMSEVALNDIRGGEAPENAEILKNVLENCSSAFLETTVLNAGLGFYANGKVDSIKSGIELAREVIAQG
AALEKLHELQAEQIG

Sequences:

>Translated_335_residues
MKNELEKVMAGRDMTENEMNMLANSIIQGELSDVQIASFLVALKMKGESASELTGLARALQKAAISIPTNLTNAMDNCGT
GGDRSFSFNISTTAAFVLAAGGVNMAKHGNRSITSKSGSADVLEALGINLYLPAEKLAQVFDKVGLVFLFAQNLHPAMKY
FTPVRRQLEIPTIMNLTGPLINPIPLDTQLLGTSRPDLLELTANVLKGLGRKRALVITGEGGMDEATPFGLNHYALLENG
EVTLHKFRAADVGMSEVALNDIRGGEAPENAEILKNVLENCSSAFLETTVLNAGLGFYANGKVDSIKSGIELAREVIAQG
AALEKLHELQAEQIG
>Mature_335_residues
MKNELEKVMAGRDMTENEMNMLANSIIQGELSDVQIASFLVALKMKGESASELTGLARALQKAAISIPTNLTNAMDNCGT
GGDRSFSFNISTTAAFVLAAGGVNMAKHGNRSITSKSGSADVLEALGINLYLPAEKLAQVFDKVGLVFLFAQNLHPAMKY
FTPVRRQLEIPTIMNLTGPLINPIPLDTQLLGTSRPDLLELTANVLKGLGRKRALVITGEGGMDEATPFGLNHYALLENG
EVTLHKFRAADVGMSEVALNDIRGGEAPENAEILKNVLENCSSAFLETTVLNAGLGFYANGKVDSIKSGIELAREVIAQG
AALEKLHELQAEQIG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=275, Percent_Identity=40.7272727272727, Blast_Score=185, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6320561, Length=270, Percent_Identity=28.8888888888889, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 35727; Mature: 35727

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNELEKVMAGRDMTENEMNMLANSIIQGELSDVQIASFLVALKMKGESASELTGLARAL
CCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QKAAISIPTNLTNAMDNCGTGGDRSFSFNISTTAAFVLAAGGVNMAKHGNRSITSKSGSA
HHHHHCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHHHCCCCCHHHCCCCCCCCCCCCH
DVLEALGINLYLPAEKLAQVFDKVGLVFLFAQNLHPAMKYFTPVRRQLEIPTIMNLTGPL
HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCCCCC
INPIPLDTQLLGTSRPDLLELTANVLKGLGRKRALVITGEGGMDEATPFGLNHYALLENG
CCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECC
EVTLHKFRAADVGMSEVALNDIRGGEAPENAEILKNVLENCSSAFLETTVLNAGLGFYAN
CEEEEEEHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GKVDSIKSGIELAREVIAQGAALEKLHELQAEQIG
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNELEKVMAGRDMTENEMNMLANSIIQGELSDVQIASFLVALKMKGESASELTGLARAL
CCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QKAAISIPTNLTNAMDNCGTGGDRSFSFNISTTAAFVLAAGGVNMAKHGNRSITSKSGSA
HHHHHCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHHHCCCCCHHHCCCCCCCCCCCCH
DVLEALGINLYLPAEKLAQVFDKVGLVFLFAQNLHPAMKYFTPVRRQLEIPTIMNLTGPL
HHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCCCCC
INPIPLDTQLLGTSRPDLLELTANVLKGLGRKRALVITGEGGMDEATPFGLNHYALLENG
CCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECC
EVTLHKFRAADVGMSEVALNDIRGGEAPENAEILKNVLENCSSAFLETTVLNAGLGFYAN
CEEEEEEHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GKVDSIKSGIELAREVIAQGAALEKLHELQAEQIG
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400208; 11337471 [H]