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The map label for this gene is purE [H]

Identifier: 125623836

GI number: 125623836

Start: 965608

End: 966093

Strand: Direct

Name: purE [H]

Synonym: llmg_0999

Alternate gene names: 125623836

Gene position: 965608-966093 (Clockwise)

Preceding gene: 125623835

Following gene: 125623837

Centisome position: 38.17

GC content: 42.8

Gene sequence:

>486_bases
ATGACAGAAGTTGCAATTATCATGGGTTCAAGTTCAGATTGGGCCACAATGAAAGAAACAGCGAAGATTTTAGATGATTT
TGGGTTAGCTTATGAGAAAAAAGTTGTCTCAGCTCATCGGACACCGGCTTTAATGGCTGAATTTTCCAATCAGGCCCATG
AACAAGGCTATAAGGTTATCATTGCTGGCGCTGGTGGAGCCGCACACTTACCAGGAATGGTTGCTGCTCAGACGCTTGTT
CCAGTGATTGGTGTGCCAATCAAATCACGGGCTTTATCCGGTCTTGACTCTCTTTATTCAATTGTTCAAATGCCAGCAGG
CGTTCCTGTAGCGACAATGGCAATTGGAGAGGCTGGGGCAAAAAATGCGGCATTATTTGCCTTGCAACTTTTGGCAAATA
ATGATGATGATTTATACAATAAATTAGTGAACTATCGGGCAGCCGCTCAAGAAATGGTTGAGCAATCAAACAATGAATTG
AAATGA

Upstream 100 bases:

>100_bases
ATGCAGAGCTCTCAATTGCAGTTGGAAGTAATCAAGCATTAGATTTTGCAGATATTCATTTAAATGAAAAAGAAATTTTA
AGATATTTGGAGAAAATAAA

Downstream 100 bases:

>100_bases
TTTAATAAAAATACAAAAGCGGTTAGATTTCTAAAAATGAAGGGTAGGAAAACTTGTGATAAAGAATACAAAGCAAACGA
TTGGAATCATTGGTGGAGGT

Product: phosphoribosylaminoimidazole carboxylase catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTEVAIIMGSSSDWATMKETAKILDDFGLAYEKKVVSAHRTPALMAEFSNQAHEQGYKVIIAGAGGAAHLPGMVAAQTLV
PVIGVPIKSRALSGLDSLYSIVQMPAGVPVATMAIGEAGAKNAALFALQLLANNDDDLYNKLVNYRAAAQEMVEQSNNEL
K

Sequences:

>Translated_161_residues
MTEVAIIMGSSSDWATMKETAKILDDFGLAYEKKVVSAHRTPALMAEFSNQAHEQGYKVIIAGAGGAAHLPGMVAAQTLV
PVIGVPIKSRALSGLDSLYSIVQMPAGVPVATMAIGEAGAKNAALFALQLLANNDDDLYNKLVNYRAAAQEMVEQSNNEL
K
>Mature_160_residues
TEVAIIMGSSSDWATMKETAKILDDFGLAYEKKVVSAHRTPALMAEFSNQAHEQGYKVIIAGAGGAAHLPGMVAAQTLVP
VIGVPIKSRALSGLDSLYSIVQMPAGVPVATMAIGEAGAKNAALFALQLLANNDDDLYNKLVNYRAAAQEMVEQSNNELK

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=151, Percent_Identity=60.2649006622517, Blast_Score=158, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324702, Length=150, Percent_Identity=53.3333333333333, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 16991; Mature: 16860

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVAIIMGSSSDWATMKETAKILDDFGLAYEKKVVSAHRTPALMAEFSNQAHEQGYKVI
CCEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEE
IAGAGGAAHLPGMVAAQTLVPVIGVPIKSRALSGLDSLYSIVQMPAGVPVATMAIGEAGA
EEECCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
KNAALFALQLLANNDDDLYNKLVNYRAAAQEMVEQSNNELK
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TEVAIIMGSSSDWATMKETAKILDDFGLAYEKKVVSAHRTPALMAEFSNQAHEQGYKVI
CEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEE
IAGAGGAAHLPGMVAAQTLVPVIGVPIKSRALSGLDSLYSIVQMPAGVPVATMAIGEAGA
EEECCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
KNAALFALQLLANNDDDLYNKLVNYRAAAQEMVEQSNNELK
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]