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The map label for this gene is tkt [H]

Identifier: 125623712

GI number: 125623712

Start: 837369

End: 839345

Strand: Direct

Name: tkt [H]

Synonym: llmg_0868

Alternate gene names: 125623712

Gene position: 837369-839345 (Clockwise)

Preceding gene: 125623711

Following gene: 125623713

Centisome position: 33.1

GC content: 39.76

Gene sequence:

>1977_bases
ATGTTTGATACTACTGATCAATTGGCTGTAAATACGATTCGTACTCTATCATTAGATGCGATTCAAAAAGCAAATTCAGG
ACATCCTGGACTTCCAATGGGCTCTGCCCCAATGGCTTATGTACTTTGGAGCAAGTTTCTTAATGTAAACCCAAAAACGA
GTCGTAAATGGTCAAATCGTGACCGTTTTGTCTTGTCGGCTGGTCATGGTTCTGCAATGTTATATAGTTTGTTACACTTG
GCAGGATATAATGTAACGACTGATGATTTAAAAGGTTTCCGTCAATGGCAATCAAAAACACCAGGACATCCAGAAGTTAA
CCATACAGATGGTGTCGAAGCAACAACAGGTCCTTTGGGACAAGGAATTGCCAATGCTGTTGGAATGGCAATGGCTGAGG
CACATTTAGCTGCACAATATAATAAACCTGGTTTTGATATTGTTGACCATTATACTTATGCCTTAAATGGTGATGGTGAT
TTAATGGAAGGTGTTTCACAAGAAGCTGCTTCACTTGCAGGTAAATTGAAACTTGGTAAATTGATTCTTTTCTATGATTC
AAATAATATCTCTCTTGATGGTGATTTATCTATGTCATTTATTGATGATATTCAAAAACGTTTTGAATCATATGGTTGGC
AACATTTATTGGTAAAAGATGGTAATGATTTGGAAGAAATTGCTGCTGCTGTCGAAGTGGCTAAAGCTGAAAAATCTAAA
CCAACAATTATTGAAGTTAAAACAGTCATTGGTTTTGGTGCTGAAAAACAAGGAACTTCAGCAGTTCATGGAGCCCCTCT
TGGAGCTGACGGTGTAGCTTTTGCTAAGAAAGCTTATGGTTGGGATTATCCAGAATTTACTGTTCCTGAAGAAGTTTCAA
AACGCTTTTTAGAAACGACAGTTGCGCGTGGTGAAGCGATGGAGCAAGTATGGCGTGGCACTTTTGATGATTATTCTGAA
AAATACCCTGAGCTTGCTGAACAATATGTAAAAGCTTTTGAAAATGAAACACCAGAGCTTACATTGACCAAACATGAAAT
GGAAACAAGTAAGGCAAGTCGTGTGACTTCCCAAGAAGCTATTCAAGAACTATCTGCTCAAATGCCAAATCTCTGGGGAG
GGTCTGCTGACCTTTCAGCTTCAAATAATACAATGGTTAAAGTTGAAGAAGACTTCATGCCAGATAACTATGTTGGACGT
AATATTTGGTTCGGTGTTCGTGAATTCGCAATGGGTGCCATTATGAACGGAATTGCTTTGCATGGTGGAACTCGTGTTTA
TGGTGGAACATTCTTTGTCTTCTCAAACTATATGCTTCCTTCTGTTCGGATGGCTGCTCTACAAAGCTTGCCAGTTACTT
ATGTCTGGACACATGATTCGATTGCTGTCGGTGAAGATGGACCAACTCATGAACCTGTCGAACAACTGGCTTCTGTTCGT
TCAATTCCGAATTTGGATGTGATTCGTCCAGCTGATGGAAATGAAGTAGTGGCTGCATGGCGTCGTGCTGCTTCAAGTAA
AAGCCGTCCAACCGCACTTATTTTGACTCGTCAAAATCTTCCAGTTTTACCTGATACTTATGAATTGGCTGAAGAAGGTT
TAAATCGTGGGGCTTATATTCTTTCTAAAGAAGAAGGTAAACTTGAAGGAATTATCATTGCGACTGGTTCAGAAGTAGCT
TTGGCACTTGAAGCGAAGAAGACTTTAGGTTCTGGTATTCGTGTTGTTTCAATGCCTTCAATGAATATCTTTGATGAGCA
GTCAGCAGACTATCGCGAAGAAATTTTACCTAAATCAGTTAGACGTCGTTTAGCGATTGAAGCTGGAACAAGTTACGGTT
GGGGTAAATATGTTGGACTTGATGGTGCAACAGTTACAGTAGACACTTGGGGCGCTTCGGCACCAGCAAATATCGTTCTT
CCGGCTTACGGATTTACCGCTGAAAATGTAATTAAAGTATATCAATCTTTAGATTGA

Upstream 100 bases:

>100_bases
AAAAACTAAAAAAAAGAAAAAGATTTTAATTTCAGAGAATGAAAACCGTTTCTAACTTGTGTTATAATGTGAGTATAAAT
AAAAAATATGGAGAAATCTT

Downstream 100 bases:

>100_bases
GTAATCTATAAAATAAGCTTTGACAGATGTCAAGGCTTATTTGTTTGTCAGTAACATTTATTACTGATAAAATTTACTGA
GGGTTCTATTTTGATAAAAC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNRDRFVLSAGHGSAMLYSLLHL
AGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGD
LMEGVSQEAASLAGKLKLGKLILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
PTIIEVKTVIGFGAEKQGTSAVHGAPLGADGVAFAKKAYGWDYPEFTVPEEVSKRFLETTVARGEAMEQVWRGTFDDYSE
KYPELAEQYVKAFENETPELTLTKHEMETSKASRVTSQEAIQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYVGR
NIWFGVREFAMGAIMNGIALHGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYILSKEEGKLEGIIIATGSEVA
LALEAKKTLGSGIRVVSMPSMNIFDEQSADYREEILPKSVRRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVL
PAYGFTAENVIKVYQSLD

Sequences:

>Translated_658_residues
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNRDRFVLSAGHGSAMLYSLLHL
AGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGD
LMEGVSQEAASLAGKLKLGKLILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
PTIIEVKTVIGFGAEKQGTSAVHGAPLGADGVAFAKKAYGWDYPEFTVPEEVSKRFLETTVARGEAMEQVWRGTFDDYSE
KYPELAEQYVKAFENETPELTLTKHEMETSKASRVTSQEAIQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYVGR
NIWFGVREFAMGAIMNGIALHGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYILSKEEGKLEGIIIATGSEVA
LALEAKKTLGSGIRVVSMPSMNIFDEQSADYREEILPKSVRRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVL
PAYGFTAENVIKVYQSLD
>Mature_658_residues
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNRDRFVLSAGHGSAMLYSLLHL
AGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGD
LMEGVSQEAASLAGKLKLGKLILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
PTIIEVKTVIGFGAEKQGTSAVHGAPLGADGVAFAKKAYGWDYPEFTVPEEVSKRFLETTVARGEAMEQVWRGTFDDYSE
KYPELAEQYVKAFENETPELTLTKHEMETSKASRVTSQEAIQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYVGR
NIWFGVREFAMGAIMNGIALHGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYILSKEEGKLEGIIIATGSEVA
LALEAKKTLGSGIRVVSMPSMNIFDEQSADYREEILPKSVRRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVL
PAYGFTAENVIKVYQSLD

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=524, Percent_Identity=27.6717557251908, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI4507521, Length=524, Percent_Identity=27.6717557251908, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI133778974, Length=530, Percent_Identity=26.4150943396226, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI225637463, Length=421, Percent_Identity=23.9904988123515, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI225637459, Length=421, Percent_Identity=23.9904988123515, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI225637461, Length=421, Percent_Identity=23.9904988123515, Blast_Score=96, Evalue=9e-20,
Organism=Escherichia coli, GI48994911, Length=660, Percent_Identity=50.3030303030303, Blast_Score=614, Evalue=1e-177,
Organism=Escherichia coli, GI1788808, Length=653, Percent_Identity=48.8514548238897, Blast_Score=598, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI17539652, Length=567, Percent_Identity=25.7495590828924, Blast_Score=146, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6325331, Length=670, Percent_Identity=48.2089552238806, Blast_Score=587, Evalue=1e-168,
Organism=Saccharomyces cerevisiae, GI6319593, Length=666, Percent_Identity=46.8468468468468, Blast_Score=555, Evalue=1e-159,
Organism=Drosophila melanogaster, GI45551847, Length=562, Percent_Identity=27.5800711743772, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45550715, Length=562, Percent_Identity=27.5800711743772, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24666278, Length=508, Percent_Identity=27.3622047244095, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24645119, Length=534, Percent_Identity=27.3408239700375, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71713; Mature: 71713

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNR
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DRFVLSAGHGSAMLYSLLHLAGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLG
CCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
QGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGDLMEGVSQEAASLAGKLKLGK
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECEEEEECCCCHHHHHHHHHHHHHHCCEEECE
LILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
EEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCC
PTIIEVKTVIGFGAEKQGTSAVHGAPLGADGVAFAKKAYGWDYPEFTVPEEVSKRFLETT
CCEEEEEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VARGEAMEQVWRGTFDDYSEKYPELAEQYVKAFENETPELTLTKHEMETSKASRVTSQEA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
IQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYVGRNIWFGVREFAMGAIMNGIAL
HHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEE
HGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
CCCCEEECCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHH
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYI
CCCCCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEE
LSKEEGKLEGIIIATGSEVALALEAKKTLGSGIRVVSMPSMNIFDEQSADYREEILPKSV
EECCCCCEEEEEEECCCCEEEEEEHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
RRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVLPAYGFTAENVIKVYQSLD
HHHEEHCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNR
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DRFVLSAGHGSAMLYSLLHLAGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLG
CCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCH
QGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGDLMEGVSQEAASLAGKLKLGK
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECEEEEECCCCHHHHHHHHHHHHHHCCEEECE
LILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
EEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCC
PTIIEVKTVIGFGAEKQGTSAVHGAPLGADGVAFAKKAYGWDYPEFTVPEEVSKRFLETT
CCEEEEEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VARGEAMEQVWRGTFDDYSEKYPELAEQYVKAFENETPELTLTKHEMETSKASRVTSQEA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHH
IQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYVGRNIWFGVREFAMGAIMNGIAL
HHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEE
HGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
CCCCEEECCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHH
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYI
CCCCCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEE
LSKEEGKLEGIIIATGSEVALALEAKKTLGSGIRVVSMPSMNIFDEQSADYREEILPKSV
EECCCCCEEEEEEECCCCEEEEEEHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHH
RRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVLPAYGFTAENVIKVYQSLD
HHHEEHCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA