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The map label for this gene is ccpA [H]

Identifier: 125623627

GI number: 125623627

Start: 764304

End: 765302

Strand: Direct

Name: ccpA [H]

Synonym: llmg_0775

Alternate gene names: 125623627

Gene position: 764304-765302 (Clockwise)

Preceding gene: 125623625

Following gene: 125623628

Centisome position: 30.22

GC content: 36.34

Gene sequence:

>999_bases
ATGGTAGAATCAACAACAACAATTTATGATGTGGCACGTGTCGCCGGAGTCTCAATGGCAACCGTTAGTCGCGTTGTGAA
TGGAAATGCAAATGTGAAGGAAAAGACGCGCCAGAAGGTTTTAGAAGCTATTGCTGAGCTTGACTATCGTCCTAACGCTG
TGGCACGTGGACTTGCAAGTAAACGGACAACAACAGTCGGTGTTATCTTGCCAACAATCACTTCAACATACTTCGCAGCT
ATTACCCGCGGAGTTGATGATATCGCTTCCATGTATAAATACAACATGATTTTAGCTAATAGTGATAATGATGTTGAAAA
AGAAGAAAAAGTTTTAGAAACTTTCTTGTCAAAACAAGTAGACGGAATTGTTTATATGGGTTCATCATTAGATGAAAAAA
TTAGAACTTCCCTTAAAAATTCAAGAACACCTGTTGTTTTAGTAGGAACAATTGATGGGGATAAAGAAATTCCATCAGTT
AATATTGATTACCATTTGGCTGCTTACCAATCAACAACTAAATTAATCGAAAATGGAAATAAGAAAATTGCTTACATCAT
GGGTTCATTGAAAGATGTTGAAAACACTGAACGTATGGTTGGTTATCAAGAAGCTTTACTTGAAGCAAATATTGAATTTG
ATGAAAATCTTGTTTTTGAAGGTAATTATAGCTACGAACAAGGCAAATCACTTGCTGAACGCTTACTTGAAAGAGGAGCA
ACCTCTGCAGTTGTTTCACATGATACGGTAGCCGTTGGCCTCTTGTCTGCGATGATGGATAAAGAAGTTAAAGTTCCTGA
AGAATTTGAAATCATTTCTGGTGCAAACTCACCAATTACTCAATATACTTATCCAACATTAACTTCTGTTAATCAACCGC
TTTATGATTTAGGGGCTGTAGCAATGCGTCTTTTGACAAAATTAATGCTTAAAGAAGATGTTGAGCAAAACCAATTAGTT
TTGGATCATGAAATCATTTCTCGTCGCTCAACTAAATAA

Upstream 100 bases:

>100_bases
TTGAAGGTTGAAAAGGTTTACAGTTCATGATATAATTTGTAAATGAAAATGGTTTTCATAAATACTATGAATAAAAAGAA
AAGAAAGAGGATAGCCAAAT

Downstream 100 bases:

>100_bases
AAATTAAGCCCAATTAGGGGCTTTTTTTATTTAAAGTAAAAAGTATTTGACATTTACAAGAAAAGTCGCAATAATAGATA
GACAATAGAAAATGACTTTA

Product: catabolite control protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLASKRTTTVGVILPTITSTYFAA
ITRGVDDIASMYKYNMILANSDNDVEKEEKVLETFLSKQVDGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSV
NIDYHLAAYQSTTKLIENGNKKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKSLAERLLERGA
TSAVVSHDTVAVGLLSAMMDKEVKVPEEFEIISGANSPITQYTYPTLTSVNQPLYDLGAVAMRLLTKLMLKEDVEQNQLV
LDHEIISRRSTK

Sequences:

>Translated_332_residues
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLASKRTTTVGVILPTITSTYFAA
ITRGVDDIASMYKYNMILANSDNDVEKEEKVLETFLSKQVDGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSV
NIDYHLAAYQSTTKLIENGNKKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKSLAERLLERGA
TSAVVSHDTVAVGLLSAMMDKEVKVPEEFEIISGANSPITQYTYPTLTSVNQPLYDLGAVAMRLLTKLMLKEDVEQNQLV
LDHEIISRRSTK
>Mature_332_residues
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLASKRTTTVGVILPTITSTYFAA
ITRGVDDIASMYKYNMILANSDNDVEKEEKVLETFLSKQVDGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSV
NIDYHLAAYQSTTKLIENGNKKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKSLAERLLERGA
TSAVVSHDTVAVGLLSAMMDKEVKVPEEFEIISGANSPITQYTYPTLTSVNQPLYDLGAVAMRLLTKLMLKEDVEQNQLV
LDHEIISRRSTK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes and in the positive regulation of genes involved in excretion of excess carbon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=332, Percent_Identity=31.6265060240964, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=31.0030395136778, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1788474, Length=300, Percent_Identity=31, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=31.3333333333333, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=29.1793313069909, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787580, Length=327, Percent_Identity=29.9694189602446, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789202, Length=292, Percent_Identity=30.8219178082192, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790715, Length=337, Percent_Identity=26.4094955489614, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI48994940, Length=316, Percent_Identity=28.7974683544304, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786540, Length=334, Percent_Identity=28.1437125748503, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787906, Length=328, Percent_Identity=27.7439024390244, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786268, Length=310, Percent_Identity=25.4838709677419, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1789456, Length=295, Percent_Identity=25.4237288135593, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790689, Length=321, Percent_Identity=21.4953271028037, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36685; Mature: 36685

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLAS
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KRTTTVGVILPTITSTYFAAITRGVDDIASMYKYNMILANSDNDVEKEEKVLETFLSKQV
CCCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHC
DGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSVNIDYHLAAYQSTTKLIENGN
CCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHCCC
KKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKSLAERLLERGA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
TSAVVSHDTVAVGLLSAMMDKEVKVPEEFEIISGANSPITQYTYPTLTSVNQPLYDLGAV
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHHCCCCHHHHHHH
AMRLLTKLMLKEDVEQNQLVLDHEIISRRSTK
HHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCC
>Mature Secondary Structure
MVESTTTIYDVARVAGVSMATVSRVVNGNANVKEKTRQKVLEAIAELDYRPNAVARGLAS
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KRTTTVGVILPTITSTYFAAITRGVDDIASMYKYNMILANSDNDVEKEEKVLETFLSKQV
CCCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHC
DGIVYMGSSLDEKIRTSLKNSRTPVVLVGTIDGDKEIPSVNIDYHLAAYQSTTKLIENGN
CCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHCCC
KKIAYIMGSLKDVENTERMVGYQEALLEANIEFDENLVFEGNYSYEQGKSLAERLLERGA
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
TSAVVSHDTVAVGLLSAMMDKEVKVPEEFEIISGANSPITQYTYPTLTSVNQPLYDLGAV
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHHCCCCHHHHHHH
AMRLLTKLMLKEDVEQNQLVLDHEIISRRSTK
HHHHHHHHHHHHCCCCCCEEEHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]