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The map label for this gene is dxsB [H]

Identifier: 125623603

GI number: 125623603

Start: 736077

End: 737819

Strand: Direct

Name: dxsB [H]

Synonym: llmg_0749

Alternate gene names: 125623603

Gene position: 736077-737819 (Clockwise)

Preceding gene: 125623602

Following gene: 125623604

Centisome position: 29.1

GC content: 37.41

Gene sequence:

>1743_bases
ATGTCAGTTTTAGAAAAAATAGACAGCCCAGCAGATTTAAAAAAGATTTCAAATAAAGAATTAGAAGAATTAGCTTCAGA
AATTCGAGCAGCAGTCCTTCACAAAGTATCAAATGTCGGTGGTCACGTTGGTCCAAATTTAGGCGTGACTGAATTAACAA
TTGCCCTTCACAAAGTTTTCAATTCACCAGTTGATAAGTTTATTTGGGATGTTTCCCACCAAACTTATCCACACAAAATT
TTGACTGGACGTAAAAATGGATTTACTGATGGACATTTCCATGACATTACTCCTTATACCAGTCAAAGAGAATCTGAGCA
CGACTTTTTCACCGTTGGACATACCTCAACATCCATTGCTAATGCCTTAGGTTATGCCAAAGCGCGTGATTTGACAAAGG
ATAAAGGAAATATTATTGCGGTAATTGGCGATGGTTCAATTTCAGGTGGACTTGCTATGGAAGCTCTCAATAACGCTGGA
GATTTCCAAGGAAACCTGATCATTTTATTCAATGATAATCAAATGTCAATTGCTGAAAACCATGGGGGACTTTACCGTAA
TCTAGCCGAACTTCGGGCGACAAATGGTCAAGCTGAAAATAACTTCTTTAAAACATTTGGTTTAGATTATAAATATTTAG
AAAATGGAAATGATATTGAATCACTTGTCAACTTATTTGAAGAAGTAAAAGATATTGACCATCCAATCGTTCTTCATATT
CATACTGAAAAAGGTCGCGGTTACCAACCAGCCCTTGAAAATAAGGAAGCTTTCCACTGGCATATGCCCTTTGATCTTGA
AACAGGTCAATCGAAAGTGACTGATTCTGGCAAATCTTATAGTTCTATCATGTTAGATTACATGGACAAAAAAGTTTCAG
AAGGTTTACCACTTGTAGCTATCAATGCAGCAATCCCTGGAATTTTTGGCTTGAAACAATTTGCAGCTAAATATCCAGAC
CGTTATATTGACGCTGGAATTGCCGAACAATTTACCATAACATTTGGTGGGGCAATGGCTGCAGCTGGTGCTCGTCCAAT
CATTTTCCACAATTCTACCTTTGTGCAACGAGCTTATGACCAATTTTGGCATGATTTAGCAATTAATGAAGAACCAGCGA
TTGTCATTGTTAAAGGTGGGGTTATTTCAGGTTCAGATGAAACGCACCAAGGCTCATCAGCCATGACTTGGATTTCAAAC
ATTCCAAATATCAAATATCTTGCTCCAACATCTGAAGAAGAATTCATTTCAATTCTTGATTGGGCACTTGACCAACATGA
AGAACCAGTCGTTATTCAAATGCCAGAACATGGATTAGAATCACGTCCAACAGTTCTAACAGATTTTTCGACGAGTTCAT
ATCAAATGACAAAAGCTGGTGAAAAAGTTGCCATTTTGGCTCTTGGTGGACTTTATTCACATGGTGAAAAAGTCGCTAAG
ATTTTAGCTGAAAATGGAGTTAATCCTACACTTGTTAATCCAATTTTCATCAATGATTTGGACCAAGCTTTCCTTGAAAA
CTTAGTTGAAAATCATCAAGTGATTGCCACTATCGAAGATGGAATTCTTGACGGAGGATTTGGTCAAAAAGTAGCCTCAT
TCCTCGGGAAATATGATGTGAAAGTTTTAAATTTTGGAGCGAAACGTGAATTTAATGATTCTGTTCCTGTTGCTGAACTT
TATGACCGCTACCACCTTACCCCTGAATTGATGGTTGCTGATATTCTGAGCCTTTTAAAATAA

Upstream 100 bases:

>100_bases
CATCCAAATTATGACAATTTTGTCAGTCAATTTACTAGTTTTTTAAAGGCAAATACTGTCAGTAAAAACTAAGTAAATCT
ATAAAGGAGAAAAATCAAAA

Downstream 100 bases:

>100_bases
AAACTTTTACTGACAAAGTCCCAATCATTTCTGTCAGTAAAAAATAAATTACTGACTAATCTGTCAGTAAAATTAAGAAG
AATGAGTATAGATTCTTTCT

Product: 1-deoxy-D-xylulose-5-phosphate synthase

Products: NA

Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS [H]

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MSVLEKIDSPADLKKISNKELEELASEIRAAVLHKVSNVGGHVGPNLGVTELTIALHKVFNSPVDKFIWDVSHQTYPHKI
LTGRKNGFTDGHFHDITPYTSQRESEHDFFTVGHTSTSIANALGYAKARDLTKDKGNIIAVIGDGSISGGLAMEALNNAG
DFQGNLIILFNDNQMSIAENHGGLYRNLAELRATNGQAENNFFKTFGLDYKYLENGNDIESLVNLFEEVKDIDHPIVLHI
HTEKGRGYQPALENKEAFHWHMPFDLETGQSKVTDSGKSYSSIMLDYMDKKVSEGLPLVAINAAIPGIFGLKQFAAKYPD
RYIDAGIAEQFTITFGGAMAAAGARPIIFHNSTFVQRAYDQFWHDLAINEEPAIVIVKGGVISGSDETHQGSSAMTWISN
IPNIKYLAPTSEEEFISILDWALDQHEEPVVIQMPEHGLESRPTVLTDFSTSSYQMTKAGEKVAILALGGLYSHGEKVAK
ILAENGVNPTLVNPIFINDLDQAFLENLVENHQVIATIEDGILDGGFGQKVASFLGKYDVKVLNFGAKREFNDSVPVAEL
YDRYHLTPELMVADILSLLK

Sequences:

>Translated_580_residues
MSVLEKIDSPADLKKISNKELEELASEIRAAVLHKVSNVGGHVGPNLGVTELTIALHKVFNSPVDKFIWDVSHQTYPHKI
LTGRKNGFTDGHFHDITPYTSQRESEHDFFTVGHTSTSIANALGYAKARDLTKDKGNIIAVIGDGSISGGLAMEALNNAG
DFQGNLIILFNDNQMSIAENHGGLYRNLAELRATNGQAENNFFKTFGLDYKYLENGNDIESLVNLFEEVKDIDHPIVLHI
HTEKGRGYQPALENKEAFHWHMPFDLETGQSKVTDSGKSYSSIMLDYMDKKVSEGLPLVAINAAIPGIFGLKQFAAKYPD
RYIDAGIAEQFTITFGGAMAAAGARPIIFHNSTFVQRAYDQFWHDLAINEEPAIVIVKGGVISGSDETHQGSSAMTWISN
IPNIKYLAPTSEEEFISILDWALDQHEEPVVIQMPEHGLESRPTVLTDFSTSSYQMTKAGEKVAILALGGLYSHGEKVAK
ILAENGVNPTLVNPIFINDLDQAFLENLVENHQVIATIEDGILDGGFGQKVASFLGKYDVKVLNFGAKREFNDSVPVAEL
YDRYHLTPELMVADILSLLK
>Mature_579_residues
SVLEKIDSPADLKKISNKELEELASEIRAAVLHKVSNVGGHVGPNLGVTELTIALHKVFNSPVDKFIWDVSHQTYPHKIL
TGRKNGFTDGHFHDITPYTSQRESEHDFFTVGHTSTSIANALGYAKARDLTKDKGNIIAVIGDGSISGGLAMEALNNAGD
FQGNLIILFNDNQMSIAENHGGLYRNLAELRATNGQAENNFFKTFGLDYKYLENGNDIESLVNLFEEVKDIDHPIVLHIH
TEKGRGYQPALENKEAFHWHMPFDLETGQSKVTDSGKSYSSIMLDYMDKKVSEGLPLVAINAAIPGIFGLKQFAAKYPDR
YIDAGIAEQFTITFGGAMAAAGARPIIFHNSTFVQRAYDQFWHDLAINEEPAIVIVKGGVISGSDETHQGSSAMTWISNI
PNIKYLAPTSEEEFISILDWALDQHEEPVVIQMPEHGLESRPTVLTDFSTSSYQMTKAGEKVAILALGGLYSHGEKVAKI
LAENGVNPTLVNPIFINDLDQAFLENLVENHQVIATIEDGILDGGFGQKVASFLGKYDVKVLNFGAKREFNDSVPVAELY
DRYHLTPELMVADILSLLK

Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) [H]

COG id: COG1154

COG function: function code HI; Deoxyxylulose-5-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family. DXPS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786622, Length=586, Percent_Identity=34.4709897610922, Blast_Score=339, Evalue=3e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005477
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.7 [H]

Molecular weight: Translated: 63863; Mature: 63732

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLEKIDSPADLKKISNKELEELASEIRAAVLHKVSNVGGHVGPNLGVTELTIALHKVF
CCHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
NSPVDKFIWDVSHQTYPHKILTGRKNGFTDGHFHDITPYTSQRESEHDFFTVGHTSTSIA
CCCHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHH
NALGYAKARDLTKDKGNIIAVIGDGSISGGLAMEALNNAGDFQGNLIILFNDNQMSIAEN
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEECCCCEEEECC
HGGLYRNLAELRATNGQAENNFFKTFGLDYKYLENGNDIESLVNLFEEVKDIDHPIVLHI
CCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
HTEKGRGYQPALENKEAFHWHMPFDLETGQSKVTDSGKSYSSIMLDYMDKKVSEGLPLVA
ECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
INAAIPGIFGLKQFAAKYPDRYIDAGIAEQFTITFGGAMAAAGARPIIFHNSTFVQRAYD
ECCCCCCHHHHHHHHHHCCHHHHCCCCCCEEEEEECCHHHHCCCCEEEEECCHHHHHHHH
QFWHDLAINEEPAIVIVKGGVISGSDETHQGSSAMTWISNIPNIKYLAPTSEEEFISILD
HHHHHHCCCCCCCEEEEECCEECCCCCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHH
WALDQHEEPVVIQMPEHGLESRPTVLTDFSTSSYQMTKAGEKVAILALGGLYSHGEKVAK
HHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCEEEECCCCEEEEEEECCHHHHHHHHHH
ILAENGVNPTLVNPIFINDLDQAFLENLVENHQVIATIEDGILDGGFGQKVASFLGKYDV
HHHHCCCCCEEECCEEECHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCCE
KVLNFGAKREFNDSVPVAELYDRYHLTPELMVADILSLLK
EEEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SVLEKIDSPADLKKISNKELEELASEIRAAVLHKVSNVGGHVGPNLGVTELTIALHKVF
CHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
NSPVDKFIWDVSHQTYPHKILTGRKNGFTDGHFHDITPYTSQRESEHDFFTVGHTSTSIA
CCCHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHH
NALGYAKARDLTKDKGNIIAVIGDGSISGGLAMEALNNAGDFQGNLIILFNDNQMSIAEN
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCEEEEECCCCEEEECC
HGGLYRNLAELRATNGQAENNFFKTFGLDYKYLENGNDIESLVNLFEEVKDIDHPIVLHI
CCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
HTEKGRGYQPALENKEAFHWHMPFDLETGQSKVTDSGKSYSSIMLDYMDKKVSEGLPLVA
ECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
INAAIPGIFGLKQFAAKYPDRYIDAGIAEQFTITFGGAMAAAGARPIIFHNSTFVQRAYD
ECCCCCCHHHHHHHHHHCCHHHHCCCCCCEEEEEECCHHHHCCCCEEEEECCHHHHHHHH
QFWHDLAINEEPAIVIVKGGVISGSDETHQGSSAMTWISNIPNIKYLAPTSEEEFISILD
HHHHHHCCCCCCCEEEEECCEECCCCCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHH
WALDQHEEPVVIQMPEHGLESRPTVLTDFSTSSYQMTKAGEKVAILALGGLYSHGEKVAK
HHHCCCCCCEEEECCCCCCCCCCEEEEECCCCCEEEECCCCEEEEEEECCHHHHHHHHHH
ILAENGVNPTLVNPIFINDLDQAFLENLVENHQVIATIEDGILDGGFGQKVASFLGKYDV
HHHHCCCCCEEECCEEECHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCCE
KVLNFGAKREFNDSVPVAELYDRYHLTPELMVADILSLLK
EEEECCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA