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The map label for this gene is malR [H]

Identifier: 125623600

GI number: 125623600

Start: 732522

End: 733496

Strand: Direct

Name: malR [H]

Synonym: llmg_0746

Alternate gene names: 125623600

Gene position: 732522-733496 (Clockwise)

Preceding gene: 125623599

Following gene: 125623601

Centisome position: 28.96

GC content: 36.72

Gene sequence:

>975_bases
ATGGCAGTTACAATTAAAGATGTTGCAAAAAAAGCTGGTGTCAATGCTTCCACGGTAAGTCGAGTCATTAAAGACAGTTC
AGAAATTTCGGATAAAACGAAAGTAAAAGTTCGCAAAGCCATGCATGAATTGGGTTATCGTCGTAATGCAGCGGCTCAGA
TTCTAGCTTCTGGAAAAACAAATACCATTGGAGTTGTCTTTCCCCCGGTCGCCGACAAAGCAAGTCAACCTTTCTTTATG
AAAATTTTGACCTCAATCAATGAAACTGCTCGGGATTATGATGTGTCGATTGCTATCGCGACGGGACATTCGGTCGGAGA
ATTAAAGAAGCAAGTTGAACTTCAATTTTCCGAAAAACGGGTTGATGGATTCATTGTGCTTTATGCTGGAAAAAGTGATG
AAGTTCGAGATTATCTTTTAGAAAATAAGGTTCCTTTTGTTCTAGTAGGAACGCCAACAGAAGGTAAAAATGAAATTACA
CATGTGGATAATGATAATATGCTCCTTGGGCGTGAAGCTGTTCGGCTTTTAGCCCAATTAAATCATCAGAATATCTCATT
TGTAACAGATACGAAAGAAACAGAAGTTTTTGAAGAGCGTTATCAAGGCTTTAAAGATGAAGCAGAAAGATTAGGTCTCA
GCCACGATTTATTATTCATGGATAGTAATTTTTCACTAAGAAATGAAACAGCATTAGTGGTTATGGATGATGTCCTATCT
TTAAAAGTGGTGGAGCGTTTACGAAGTCAAGGACTAAATGTTCCAGAAGATGTAAGTCTCATTACTTACAACAATTCCAT
TTTTGGGGCAATGATTCACCCTTATCTCACAACCTTTGATATTCATATTGAACAATTGGGGGCAAGTGCCATCAAGAAAA
TTTTAGATTTACGAGATAATAAAGAAAACTTACCAGAAAAAACAATCATTCCTTTTGAATTAATTGTTCGGGAATCAACA
AAAGCTAGAATTTGA

Upstream 100 bases:

>100_bases
ATTAGTCTAAAATTTGGCAAAATAAAATTTGAAAGATTCAAAAAAGAATAGAGAAAGGAGCGCTGAGTTGAGCTAGCTTC
GGCTAGTTTCAAGTGAAAAT

Downstream 100 bases:

>100_bases
GTTCTAGCTTTTTTAGTTTTGTTTAAGATAGGGTTAAGCCTAGTACAAGACAAAAATATGATAATAGTGTAAAATAATAG
AAAGGAATGGGCGCGGTTTT

Product: maltose operon transcriptional repressor

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MAVTIKDVAKKAGVNASTVSRVIKDSSEISDKTKVKVRKAMHELGYRRNAAAQILASGKTNTIGVVFPPVADKASQPFFM
KILTSINETARDYDVSIAIATGHSVGELKKQVELQFSEKRVDGFIVLYAGKSDEVRDYLLENKVPFVLVGTPTEGKNEIT
HVDNDNMLLGREAVRLLAQLNHQNISFVTDTKETEVFEERYQGFKDEAERLGLSHDLLFMDSNFSLRNETALVVMDDVLS
LKVVERLRSQGLNVPEDVSLITYNNSIFGAMIHPYLTTFDIHIEQLGASAIKKILDLRDNKENLPEKTIIPFELIVREST
KARI

Sequences:

>Translated_324_residues
MAVTIKDVAKKAGVNASTVSRVIKDSSEISDKTKVKVRKAMHELGYRRNAAAQILASGKTNTIGVVFPPVADKASQPFFM
KILTSINETARDYDVSIAIATGHSVGELKKQVELQFSEKRVDGFIVLYAGKSDEVRDYLLENKVPFVLVGTPTEGKNEIT
HVDNDNMLLGREAVRLLAQLNHQNISFVTDTKETEVFEERYQGFKDEAERLGLSHDLLFMDSNFSLRNETALVVMDDVLS
LKVVERLRSQGLNVPEDVSLITYNNSIFGAMIHPYLTTFDIHIEQLGASAIKKILDLRDNKENLPEKTIIPFELIVREST
KARI
>Mature_323_residues
AVTIKDVAKKAGVNASTVSRVIKDSSEISDKTKVKVRKAMHELGYRRNAAAQILASGKTNTIGVVFPPVADKASQPFFMK
ILTSINETARDYDVSIAIATGHSVGELKKQVELQFSEKRVDGFIVLYAGKSDEVRDYLLENKVPFVLVGTPTEGKNEITH
VDNDNMLLGREAVRLLAQLNHQNISFVTDTKETEVFEERYQGFKDEAERLGLSHDLLFMDSNFSLRNETALVVMDDVLSL
KVVERLRSQGLNVPEDVSLITYNNSIFGAMIHPYLTTFDIHIEQLGASAIKKILDLRDNKENLPEKTIIPFELIVRESTK
ARI

Specific function: Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=26.6081871345029, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789202, Length=333, Percent_Identity=27.6276276276276, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=24.9221183800623, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787948, Length=335, Percent_Identity=26.865671641791, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789068, Length=335, Percent_Identity=25.6716417910448, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790194, Length=308, Percent_Identity=26.6233766233766, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788474, Length=341, Percent_Identity=26.099706744868, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786540, Length=336, Percent_Identity=27.3809523809524, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787906, Length=215, Percent_Identity=28.8372093023256, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36240; Mature: 36109

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTIKDVAKKAGVNASTVSRVIKDSSEISDKTKVKVRKAMHELGYRRNAAAQILASGKT
CEEEHHHHHHHCCCCHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
NTIGVVFPPVADKASQPFFMKILTSINETARDYDVSIAIATGHSVGELKKQVELQFSEKR
CEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCC
VDGFIVLYAGKSDEVRDYLLENKVPFVLVGTPTEGKNEITHVDNDNMLLGREAVRLLAQL
CCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCEEECHHHHHHHHHH
NHQNISFVTDTKETEVFEERYQGFKDEAERLGLSHDLLFMDSNFSLRNETALVVMDDVLS
CCCCEEEEECCHHHHHHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEHHHHH
LKVVERLRSQGLNVPEDVSLITYNNSIFGAMIHPYLTTFDIHIEQLGASAIKKILDLRDN
HHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC
KENLPEKTIIPFELIVRESTKARI
CCCCCCCCCCCHHHEEECCCCCCC
>Mature Secondary Structure 
AVTIKDVAKKAGVNASTVSRVIKDSSEISDKTKVKVRKAMHELGYRRNAAAQILASGKT
EEEHHHHHHHCCCCHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
NTIGVVFPPVADKASQPFFMKILTSINETARDYDVSIAIATGHSVGELKKQVELQFSEKR
CEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCC
VDGFIVLYAGKSDEVRDYLLENKVPFVLVGTPTEGKNEITHVDNDNMLLGREAVRLLAQL
CCEEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCCEEECHHHHHHHHHH
NHQNISFVTDTKETEVFEERYQGFKDEAERLGLSHDLLFMDSNFSLRNETALVVMDDVLS
CCCCEEEEECCHHHHHHHHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEHHHHH
LKVVERLRSQGLNVPEDVSLITYNNSIFGAMIHPYLTTFDIHIEQLGASAIKKILDLRDN
HHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCC
KENLPEKTIIPFELIVRESTKARI
CCCCCCCCCCCHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]