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The map label for this gene is spoU [H]

Identifier: 125623434

GI number: 125623434

Start: 561345

End: 562103

Strand: Direct

Name: spoU [H]

Synonym: llmg_0570

Alternate gene names: 125623434

Gene position: 561345-562103 (Clockwise)

Preceding gene: 125623432

Following gene: 125623436

Centisome position: 22.19

GC content: 36.76

Gene sequence:

>759_bases
ATGGAAATCATCAGTTCAAAAGATAATAAAAAAGTTAAAGAAGCAAGAAAATTGCTGACAAAAAAATACCGTAAAAATTC
ATATCTCATCGAAGGATTTCATTTGTTGGAGGAAGCACTGAAAGCTGGTCATTCAATAAAGCAAATTTTTGTTGAAGAAA
ATAAACTGGCTAAACTGACAGCAATGATTGGGTCTGAAAAATCACTGACAGACTTATCTGTAAATCTGGTCAGTAAAGAT
GTACTAAAATCTTTAGCTGACAGCGAAAGTCCACAAGGACTGATTGCTGAAGTGGCAATAATTGAAGAAGTTATTGATTT
TTCAGCATCAAAATTTTTACTTTTAGAAAATGTGCAAGATCCAGGAAATGTCGGAACCATGATTAGAACGGCTGATGCAG
CTGGTTTTTCAGCTGTTATTTTACTTGGTGAAACGGCAGACCTTTATAGTCCGAAGGTTATGCGTTCAATGCAAGGATCA
AATTTTCATTTAGCGATTGCCCGCATGAATGAAGAAGAATGTTTTGCTGCGCTCAAACAAGCCAAAATTTCAATCTTGAC
AACAACGCTATCAGCAAATTCTGTATCTTATAAAACTGTTGAGGAATCATCTTTTGCTTTGGTCATGGGCAATGAAGGAG
CTGGAGTATCAGACTTTGCCGTGGAATCTGCTGACAAGCTTGTTCATATTGACATGCCAGGACAAGCGGAATCTTTAAAT
GTGGCTGTAGCAGCTGGGATTTTGATGTTTTCATTGTAA

Upstream 100 bases:

>100_bases
TCATTCGTTAAATTATTGAGTGACTTGTTTATTTAAAACGTTTTCTTTTATTATAGCATAAGCATAAGCAAGATTGGCAA
AAATCTGATAAAATAAGAGA

Downstream 100 bases:

>100_bases
ATTACTGATGAGAACCCTAGCATATTCGTAAGCGCTCAAGCGCTAACGACTATCCTATGACAGAAATTGATTTTGGCTCG
TAAATACTAAAGAAACACCT

Product: rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MEIISSKDNKKVKEARKLLTKKYRKNSYLIEGFHLLEEALKAGHSIKQIFVEENKLAKLTAMIGSEKSLTDLSVNLVSKD
VLKSLADSESPQGLIAEVAIIEEVIDFSASKFLLLENVQDPGNVGTMIRTADAAGFSAVILLGETADLYSPKVMRSMQGS
NFHLAIARMNEEECFAALKQAKISILTTTLSANSVSYKTVEESSFALVMGNEGAGVSDFAVESADKLVHIDMPGQAESLN
VAVAAGILMFSL

Sequences:

>Translated_252_residues
MEIISSKDNKKVKEARKLLTKKYRKNSYLIEGFHLLEEALKAGHSIKQIFVEENKLAKLTAMIGSEKSLTDLSVNLVSKD
VLKSLADSESPQGLIAEVAIIEEVIDFSASKFLLLENVQDPGNVGTMIRTADAAGFSAVILLGETADLYSPKVMRSMQGS
NFHLAIARMNEEECFAALKQAKISILTTTLSANSVSYKTVEESSFALVMGNEGAGVSDFAVESADKLVHIDMPGQAESLN
VAVAAGILMFSL
>Mature_252_residues
MEIISSKDNKKVKEARKLLTKKYRKNSYLIEGFHLLEEALKAGHSIKQIFVEENKLAKLTAMIGSEKSLTDLSVNLVSKD
VLKSLADSESPQGLIAEVAIIEEVIDFSASKFLLLENVQDPGNVGTMIRTADAAGFSAVILLGETADLYSPKVMRSMQGS
NFHLAIARMNEEECFAALKQAKISILTTTLSANSVSYKTVEESSFALVMGNEGAGVSDFAVESADKLVHIDMPGQAESLN
VAVAAGILMFSL

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI8922534, Length=151, Percent_Identity=31.1258278145695, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1790623, Length=239, Percent_Identity=30.1255230125523, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790083, Length=144, Percent_Identity=31.25, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27207; Mature: 27207

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIISSKDNKKVKEARKLLTKKYRKNSYLIEGFHLLEEALKAGHSIKQIFVEENKLAKLT
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHHHHHCCCHHHHHH
AMIGSEKSLTDLSVNLVSKDVLKSLADSESPQGLIAEVAIIEEVIDFSASKFLLLENVQD
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
PGNVGTMIRTADAAGFSAVILLGETADLYSPKVMRSMQGSNFHLAIARMNEEECFAALKQ
CCCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHH
AKISILTTTLSANSVSYKTVEESSFALVMGNEGAGVSDFAVESADKLVHIDMPGQAESLN
HHEEEEEEEECCCCEEEEEECCCCEEEEECCCCCCCCHHHHHCCCCEEEEECCCCCCHHH
VAVAAGILMFSL
HHHHHHHHHHCC
>Mature Secondary Structure
MEIISSKDNKKVKEARKLLTKKYRKNSYLIEGFHLLEEALKAGHSIKQIFVEENKLAKLT
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHHHHHCCCHHHHHH
AMIGSEKSLTDLSVNLVSKDVLKSLADSESPQGLIAEVAIIEEVIDFSASKFLLLENVQD
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
PGNVGTMIRTADAAGFSAVILLGETADLYSPKVMRSMQGSNFHLAIARMNEEECFAALKQ
CCCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHH
AKISILTTTLSANSVSYKTVEESSFALVMGNEGAGVSDFAVESADKLVHIDMPGQAESLN
HHEEEEEEEECCCCEEEEEECCCCEEEEECCCCCCCCHHHHHCCCCEEEEECCCCCCHHH
VAVAAGILMFSL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]