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The map label for this gene is hexR [H]

Identifier: 125623302

GI number: 125623302

Start: 427409

End: 428155

Strand: Direct

Name: hexR [H]

Synonym: llmg_0435

Alternate gene names: 125623302

Gene position: 427409-428155 (Clockwise)

Preceding gene: 125623301

Following gene: 125623303

Centisome position: 16.9

GC content: 34.27

Gene sequence:

>747_bases
ATGATTTTTCTACCAGAACAAATTAGTAAACTTAATGAGCTTGAAACCTTGGTTTTTGATTTCATCATAAAATCACCCGA
AGAAGTTCAACAAATGACCATTCGGGATTTGGCAAGTCAGGTTCACGTGTCAACGTCAACAATTGTTCGTTTATGTACAA
AACTTGGTTTTGAAGGTTGGGCTGACCTAAAATTTTATCTTAAAAATCAATTGAAAGAAAAAACACCAGAAGAACAGCAC
TATGATAATATGCTTGAATTTAACATGTTTTTACGTCGAATGAATACAGATAATTACCAAGCCAAACTTAATAATGCTGC
TCAAATGATTGCTAAAGCTGATTATACTGTTTTTTTGGGACTAGGAACTTCTGGGTCATTAAGTGAGTATGCAACGAAGT
ATTTTGTAAATACAGGCCTGCGAAGTTTTGTCATCTCTGACCCCTTTCAAGCTGTTCAAGTTCAGGGGATGGGGAATGTT
GTTGCGGTGATTATGTCCGTATCCGGAGAAACTGAACAAGTTGTCAATAAAGAATTAGAATTTAAATCTGGTGGTGCAAA
AATTATTTCAATTACGAATAATGAAGATTGTACGGTAGCTAGACTCGCTGATCACCAACTCTCTTATAATCTTGTTAATG
AATGGTCTAAGCAATATCCTTTAGGAAATTTGACTACTCAACTTCCAGTACTTGCTATTTTAGAAATTTTAGCTCACAAG
TCAATTGATTATCTTGTTAAAAAATGA

Upstream 100 bases:

>100_bases
TAGATTTATGTTTTAGTTAGACACTTTGTCAGCGAATATGATAATTAGCAATGAGGCTGATAATTCTATCCTAATTAATT
CTAAACATGGAGAATAATAA

Downstream 100 bases:

>100_bases
TAAATTTGTTCCAAATGAAGAAACAAATATTTCAAAATCCTACTATTTGATAGTAGGATTTTTAATATATTAGTCCAAAA
GCTCAAAAAGGCTGATTTAA

Product: putative HTH-type transcriptional regulator

Products: NA

Alternate protein names: Glv operon regulatory protein [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MIFLPEQISKLNELETLVFDFIIKSPEEVQQMTIRDLASQVHVSTSTIVRLCTKLGFEGWADLKFYLKNQLKEKTPEEQH
YDNMLEFNMFLRRMNTDNYQAKLNNAAQMIAKADYTVFLGLGTSGSLSEYATKYFVNTGLRSFVISDPFQAVQVQGMGNV
VAVIMSVSGETEQVVNKELEFKSGGAKIISITNNEDCTVARLADHQLSYNLVNEWSKQYPLGNLTTQLPVLAILEILAHK
SIDYLVKK

Sequences:

>Translated_248_residues
MIFLPEQISKLNELETLVFDFIIKSPEEVQQMTIRDLASQVHVSTSTIVRLCTKLGFEGWADLKFYLKNQLKEKTPEEQH
YDNMLEFNMFLRRMNTDNYQAKLNNAAQMIAKADYTVFLGLGTSGSLSEYATKYFVNTGLRSFVISDPFQAVQVQGMGNV
VAVIMSVSGETEQVVNKELEFKSGGAKIISITNNEDCTVARLADHQLSYNLVNEWSKQYPLGNLTTQLPVLAILEILAHK
SIDYLVKK
>Mature_248_residues
MIFLPEQISKLNELETLVFDFIIKSPEEVQQMTIRDLASQVHVSTSTIVRLCTKLGFEGWADLKFYLKNQLKEKTPEEQH
YDNMLEFNMFLRRMNTDNYQAKLNNAAQMIAKADYTVFLGLGTSGSLSEYATKYFVNTGLRSFVISDPFQAVQVQGMGNV
VAVIMSVSGETEQVVNKELEFKSGGAKIISITNNEDCTVARLADHQLSYNLVNEWSKQYPLGNLTTQLPVLAILEILAHK
SIDYLVKK

Specific function: Positive regulator of the glv operon expression, which consists of glvA, glvR and glvC [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=244, Percent_Identity=24.1803278688525, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 28049; Mature: 28049

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00356 HTH_LACI_1 ; PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLPEQISKLNELETLVFDFIIKSPEEVQQMTIRDLASQVHVSTSTIVRLCTKLGFEGW
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC
ADLKFYLKNQLKEKTPEEQHYDNMLEFNMFLRRMNTDNYQAKLNNAAQMIAKADYTVFLG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEE
LGTSGSLSEYATKYFVNTGLRSFVISDPFQAVQVQGMGNVVAVIMSVSGETEQVVNKELE
ECCCCCHHHHHHHHHHHHCHHHHHHCCCHHHEEECCCCHHHHHHHHCCCCHHHHHHHHHC
FKSGGAKIISITNNEDCTVARLADHQLSYNLVNEWSKQYPLGNLTTQLPVLAILEILAHK
CCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
SIDYLVKK
CHHHHHCC
>Mature Secondary Structure
MIFLPEQISKLNELETLVFDFIIKSPEEVQQMTIRDLASQVHVSTSTIVRLCTKLGFEGW
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC
ADLKFYLKNQLKEKTPEEQHYDNMLEFNMFLRRMNTDNYQAKLNNAAQMIAKADYTVFLG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEE
LGTSGSLSEYATKYFVNTGLRSFVISDPFQAVQVQGMGNVVAVIMSVSGETEQVVNKELE
ECCCCCHHHHHHHHHHHHCHHHHHHCCCHHHEEECCCCHHHHHHHHCCCCHHHHHHHHHC
FKSGGAKIISITNNEDCTVARLADHQLSYNLVNEWSKQYPLGNLTTQLPVLAILEILAHK
CCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
SIDYLVKK
CHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]