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The map label for this gene is llrC [H]

Identifier: 125623281

GI number: 125623281

Start: 408233

End: 408934

Strand: Reverse

Name: llrC [H]

Synonym: llmg_0414

Alternate gene names: 125623281

Gene position: 408934-408233 (Counterclockwise)

Preceding gene: 125623287

Following gene: 125623280

Centisome position: 16.17

GC content: 38.89

Gene sequence:

>702_bases
ATGAAAAAAATTCTTGTTGTTGATGATGAAAAACCAATCTCAGATATCGTAAAATTTAATTTAACCAAAGAAGGTTTTGA
AGTATTTACAGCTTTCGATGGCGAAGAAGCCCTTGAAGCTTTTAAAGAAGTACAACCTGACCTTATTTTACTTGATTTGA
TGTTACCAAAACTTGACGGTCTTGATGTTGCACGTGAAATCCGTAAAACCTCTGACACTCCTATTATCATGGTGTCAGCT
AAAGATAGCGAGTTTGATAAAGTTATTGGACTTGAACTTGGTGCAGATGACTATGTCACTAAACCATTCTCAAATCGCGA
ACTTTTAGCTCGTATTAAAGCAAACTTGCGTCGTATCAATGTCGCACCTGCTGAATCTACTGATAATGTTAAGAAAGAAT
TGATTATCGGAAATCTCCGTATCAATCCAGCACATTATGCTGCTTACAAAAATGATAAACAACTTGACCTCACACACCGT
GAGTTTGAATTACTTTACTATCTTGCTCAACACCTCGGCGAAGTTATCACTCGTGAAAATCTTTTGGAAACAGTTTGGGG
CTACGATTACTTTGGTGATGTGCGTACAGTTGACGTTACAGTCCGCCGCTTGCGTGAAAAAGTTGAAGATACACCAAGCC
GTCCACAATACGTTTCAACACGCCGCGGGGTTGGCTATTACATGAGCAACCCACATGATTAA

Upstream 100 bases:

>100_bases
TAAAAATTGTATAATATAACTGAAACAGCTTACTTGGTTTGTTAAATCAAATAAATCCAAGTAATATTCAATAAAAAAAT
TTCTACTTGAAAGGACAACT

Downstream 100 bases:

>100_bases
ATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCCCACCTACTTCTTTTTGTCATTCTTTTCATGAGCAATTTCGATT
ATAATCTCATTCATCTTAGT

Product: two-component system regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDGLDVAREIRKTSDTPIIMVSA
KDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRINVAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHR
EFELLYYLAQHLGEVITRENLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD

Sequences:

>Translated_233_residues
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDGLDVAREIRKTSDTPIIMVSA
KDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRINVAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHR
EFELLYYLAQHLGEVITRENLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD
>Mature_233_residues
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDGLDVAREIRKTSDTPIIMVSA
KDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRINVAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHR
EFELLYYLAQHLGEVITRENLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=44.1048034934498, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=40.0862068965517, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=39.9122807017544, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=36.6071428571429, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=39.5555555555556, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=35.6521739130435, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=34.9557522123894, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=35.3982300884956, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI145693140, Length=244, Percent_Identity=30.327868852459, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=34.051724137931, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=33.4782608695652, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=33.7719298245614, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.6521739130435, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=32.4786324786325, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=35.7798165137615, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26766; Mature: 26766

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG
CCEEEEECCCCCHHHHHHHCCCHHCEEEEEECCCHHHHHHHHHCCCCEEEEEHHHCCCCC
LDVAREIRKTSDTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRIN
HHHHHHHHHCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEE
VAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITREN
CCCCCCCCHHHHHHEEECEEECCHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
LLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG
CCEEEEECCCCCHHHHHHHCCCHHCEEEEEECCCHHHHHHHHHCCCCEEEEEHHHCCCCC
LDVAREIRKTSDTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRIN
HHHHHHHHHCCCCCEEEEECCCCCCHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEE
VAPAESTDNVKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEVITREN
CCCCCCCCHHHHHHEEECEEECCHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHH
LLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNPHD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]