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The map label for this gene is trxH [H]

Identifier: 125623273

GI number: 125623273

Start: 400611

End: 400928

Strand: Direct

Name: trxH [H]

Synonym: llmg_0406

Alternate gene names: 125623273

Gene position: 400611-400928 (Clockwise)

Preceding gene: 125623272

Following gene: 125623274

Centisome position: 15.84

GC content: 34.59

Gene sequence:

>318_bases
ATGATTATTCCAGAAAATATTGAAAATTTAGCTGAGCTTGTCAAAGGCCCAGAAAAAACAGTCTTCTTTTTCACAGCTGG
TTGGTGTGGAGATTGTAATTTTATCAAACCTAAAATGCCAGAAATTGAAACAGAGAATCCAGAATTTAGATTTGTTGAAG
TAGACCGTGATGAGTACATGGATCTTGCTATCGAGTGGGGAATTATGGGAATTCCAAGTTTTGTTGTTATTGAAGATGGA
CAAGAAAAAGCTCGTCTAGTCAATAAATTACGCAAAACCAAAGAAGAAGTGAATACTTTCTTAGCAAGTGCAAAATAA

Upstream 100 bases:

>100_bases
TTGAAATCAATGCCAAAACTTTAGAAGTTTTTGAAAAAAAAGAAGAACTTCTTTAGAAAATGGTTAGAATCCATTTGAAA
AATACGAAAGGAAATACAGA

Downstream 100 bases:

>100_bases
GACTGATTTCTTGAGGTAAAATGGAGTCAAATACTGACCATTGATAAATCCAGAAATATATTCTATAATAATCACTGTTA
AGAAATTAAAAGGGAAAATT

Product: thioredoxin H-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MIIPENIENLAELVKGPEKTVFFFTAGWCGDCNFIKPKMPEIETENPEFRFVEVDRDEYMDLAIEWGIMGIPSFVVIEDG
QEKARLVNKLRKTKEEVNTFLASAK

Sequences:

>Translated_105_residues
MIIPENIENLAELVKGPEKTVFFFTAGWCGDCNFIKPKMPEIETENPEFRFVEVDRDEYMDLAIEWGIMGIPSFVVIEDG
QEKARLVNKLRKTKEEVNTFLASAK
>Mature_105_residues
MIIPENIENLAELVKGPEKTVFFFTAGWCGDCNFIKPKMPEIETENPEFRFVEVDRDEYMDLAIEWGIMGIPSFVVIEDG
QEKARLVNKLRKTKEEVNTFLASAK

Specific function: Participates In Various Redox Reactions Through The Reversible Oxidation Of Its Active Center Dithiol To A Disulfide And Catalyzes Dithiol-Disulfide Exchange Reactions. [C]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319925, Length=83, Percent_Identity=33.7349397590361, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 12087; Mature: 12087

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIPENIENLAELVKGPEKTVFFFTAGWCGDCNFIKPKMPEIETENPEFRFVEVDRDEYM
CCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHH
DLAIEWGIMGIPSFVVIEDGQEKARLVNKLRKTKEEVNTFLASAK
EEHEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIPENIENLAELVKGPEKTVFFFTAGWCGDCNFIKPKMPEIETENPEFRFVEVDRDEYM
CCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHH
DLAIEWGIMGIPSFVVIEDGQEKARLVNKLRKTKEEVNTFLASAK
EEHEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]