| Definition | Lactococcus lactis subsp. cremoris MG1363, complete genome. |
|---|---|
| Accession | NC_009004 |
| Length | 2,529,478 |
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The map label for this gene is pbp1B [H]
Identifier: 125623270
GI number: 125623270
Start: 396633
End: 399071
Strand: Direct
Name: pbp1B [H]
Synonym: llmg_0402
Alternate gene names: 125623270
Gene position: 396633-399071 (Clockwise)
Preceding gene: 125623266
Following gene: 125623272
Centisome position: 15.68
GC content: 36.82
Gene sequence:
>2439_bases ATGAAAAAAGACTCAATTGACTCGCAAGAGGAGATTCGTGCTCGTTTAAAAGAAAAAATGGATAATAAACGACGCAAACA AAGTAACTCTTCAAGGAAAAGTCCTAAAAAAAATAATAATGATAGTGATGACAGGTCAATTTTGTCCATTACTTTTAAAG TACTACGTGGTTTGAGTGTAGTATTTGGAATAGTTTTTGTCTTGGTAGGCGTCTTTGGAGCAGCAACAGGTGTGGGTTAT TTTGCTCGATTAGTTGAACAAACGAAGATACCACCCAAAGCTGAAATGCTTTCGAAAATTAATGATATACATGGGGTTTC TGTCATTAATTATAGTAATGGTCAGCCAATCTCTGATATTTCCAGTGATTTGATTCGCGTTACTGTGAAAAGTGATGATA TATCTGCTAATGTAAAAAATGCCTTGATTGCAACCGAAGATGACAGTTTTAAAACAAATAAAGGTGTTGTTCCAAAGGCT GTCATTCGGGGAATTGTTGGCTCAATTGGAGGTGGAACAAGTTCTGGTGGTTCCACCTTAACTCAACAGCTCATTAAGCA ACAAGTTTTAGGAGATAGTGTTACATTCCAACGAAAAGCTAGTGAAATCGTCTATGCACTCAAACTTAATAATTATCTGA CTAAAGATCAAATTTTGACAGATTATTTAAATGTCTCACCTTTTGGTCGCAACAATAAAGGTCAAAATATCGCTGGAGTG CAAGAAGCAGCATTAGGAATTTTTGGTAAATCGGCCAAGGATTTGACAATACCAGAGGCGGCTTTTATTGCTGGTTTACC TCAAAGTCCAATTGTCTACTCTCCTTATTCAGCGGATGGCTCCCTTAAATCCAAAGAAAATATGAGCTATGGTCTGGAGC GTCAAAAGGAAGTATTATTTTATCTTTATCGTGGGGGATATATTTCAGAGGCAGATTATAAAAAATATGTAGCCTATGAT ATTTCAAAAGAATTTTTACAACCTGGAGTTGCCGAATCACAAGAACATGGTTATTTATATAATGTAGTTTATAATGAAGC AATTACAGATATTTATAATTATTTGATTAAACGTGATAAAGTTTCTGCGACTGATTTAGGAAATGATAGTACGAAAAAAC GTTATCAAGAACTGGCGGAACAATCACTACAAAATGGTGGTTATACTGTAACAACAACAGTTAATCAAACAGTTTATGAT GCGATGCAAAAAGCTGTAACGGATTATAACGGGCTTATGCAAGATGGTACGGGAACTATCCAAACAGGGAATGTTTTAAT GGACAATAAAACAGGAGCTGTTTATGGCTTTATTGGAGGTTTAGATTTTTCACAAAGTCAAGTCAATCATGCCTTTGATA CTAAACGCTCGCCTGGGTCATCAATTAAACCAATCTTGGCTTATGGTCCAGCCATCGATATGGGACTAATGGGCTCTGCA AGTGTCTTATCAAACTATCCAGCCAAATACTCTAGTGGACAAGATATTGAACACGTAGGCTCAACTGGAACTGCAATGAT GCCATTCTCAGAAGCTCTCAATGTTTCTTATAATATTCCTGCTTATTGGACTTACCAAACGATTTTAAATAAAGGAAAAT CAGTTGAACCTTACATGACAAAGATGGGTTATGATATTGCTGATTATTCTGTAGAATCACTTCCGCTTGGTGGGGGAGTT GATCCAACGGTTGTTCAACATACGAACGGTTATCAAACGCTGGCTAATGGTGGGAAATATGAACCTTGGTATATCGTTGA TAGTATCAAAGATGATACAGGAAATGTAATCTATCAGCATAAAAGTACTGGTGGCACCCAAGCTTATTCAGAAGCAACTT CAACAATTATGGAATCAATGCTTCAAGACGCAGTGAAATCTCAAAAAACAAGTAAGTTTTATGGCAATTTACAAACGATT AACCCTTCACTAGCAACGAATGTTCAATGGGCTGGTAAAACGGGGACAACGGATGATTATACAGATGTTTGGATGATGTT ATCAACACCTTCAGTTACACTTGGTGGTTGGGCTGGACATGATGATAATTCACCGATGACAAGTAATTCAGGATATATCA ATAATGCAGCTTATATTGCACAATTGGTTAATGCGATTAATGCAGCTGATCCAAACATTTTTGGCCCTGGACAAAAATTT ACTGATCCAAATACTGATCCAAATGTTACTAAAAGTAAAGTATTGGTTTCTACAGGAGAAAAACCAGGGAAAGTCACAGT TAAACTAGCAAATGGTAAGACTCAAGAAGTCAACCTTGGCGGAGAAACAACGACTAGCTTCTGGGCTACTAAAGCAGGAG CACCTACTACTACCTATGATTTCTCTATAGGTGGGTCAGCTAGTGATATAGCTGCTGGTTGGAAGAAAATTTTACCTTCT TTCAATTTTAGTCAGACTTCCTCATCAAAAAGTAACTAA
Upstream 100 bases:
>100_bases AAAAGTAAAAAAATAACAGCACCATTTTACATTATAACAAATTACTAAAAAAAATTCTGAAAGTGGCGAAAAATTGTTTT AAATTTGATATAATAAGGGC
Downstream 100 bases:
>100_bases AAAAACACTAGGATAAATTCCTAGTGTTTTTTTATTAGAATTAGTAGTTTTTGATTTCTGCTACTTTTTCAGTATTAAGT GAAGTAATAATCGCTCTCAA
Product: penicillin-binding protein 1B
Products: NA
Alternate protein names: PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 812; Mature: 812
Protein sequence:
>812_residues MKKDSIDSQEEIRARLKEKMDNKRRKQSNSSRKSPKKNNNDSDDRSILSITFKVLRGLSVVFGIVFVLVGVFGAATGVGY FARLVEQTKIPPKAEMLSKINDIHGVSVINYSNGQPISDISSDLIRVTVKSDDISANVKNALIATEDDSFKTNKGVVPKA VIRGIVGSIGGGTSSGGSTLTQQLIKQQVLGDSVTFQRKASEIVYALKLNNYLTKDQILTDYLNVSPFGRNNKGQNIAGV QEAALGIFGKSAKDLTIPEAAFIAGLPQSPIVYSPYSADGSLKSKENMSYGLERQKEVLFYLYRGGYISEADYKKYVAYD ISKEFLQPGVAESQEHGYLYNVVYNEAITDIYNYLIKRDKVSATDLGNDSTKKRYQELAEQSLQNGGYTVTTTVNQTVYD AMQKAVTDYNGLMQDGTGTIQTGNVLMDNKTGAVYGFIGGLDFSQSQVNHAFDTKRSPGSSIKPILAYGPAIDMGLMGSA SVLSNYPAKYSSGQDIEHVGSTGTAMMPFSEALNVSYNIPAYWTYQTILNKGKSVEPYMTKMGYDIADYSVESLPLGGGV DPTVVQHTNGYQTLANGGKYEPWYIVDSIKDDTGNVIYQHKSTGGTQAYSEATSTIMESMLQDAVKSQKTSKFYGNLQTI NPSLATNVQWAGKTGTTDDYTDVWMMLSTPSVTLGGWAGHDDNSPMTSNSGYINNAAYIAQLVNAINAADPNIFGPGQKF TDPNTDPNVTKSKVLVSTGEKPGKVTVKLANGKTQEVNLGGETTTSFWATKAGAPTTTYDFSIGGSASDIAAGWKKILPS FNFSQTSSSKSN
Sequences:
>Translated_812_residues MKKDSIDSQEEIRARLKEKMDNKRRKQSNSSRKSPKKNNNDSDDRSILSITFKVLRGLSVVFGIVFVLVGVFGAATGVGY FARLVEQTKIPPKAEMLSKINDIHGVSVINYSNGQPISDISSDLIRVTVKSDDISANVKNALIATEDDSFKTNKGVVPKA VIRGIVGSIGGGTSSGGSTLTQQLIKQQVLGDSVTFQRKASEIVYALKLNNYLTKDQILTDYLNVSPFGRNNKGQNIAGV QEAALGIFGKSAKDLTIPEAAFIAGLPQSPIVYSPYSADGSLKSKENMSYGLERQKEVLFYLYRGGYISEADYKKYVAYD ISKEFLQPGVAESQEHGYLYNVVYNEAITDIYNYLIKRDKVSATDLGNDSTKKRYQELAEQSLQNGGYTVTTTVNQTVYD AMQKAVTDYNGLMQDGTGTIQTGNVLMDNKTGAVYGFIGGLDFSQSQVNHAFDTKRSPGSSIKPILAYGPAIDMGLMGSA SVLSNYPAKYSSGQDIEHVGSTGTAMMPFSEALNVSYNIPAYWTYQTILNKGKSVEPYMTKMGYDIADYSVESLPLGGGV DPTVVQHTNGYQTLANGGKYEPWYIVDSIKDDTGNVIYQHKSTGGTQAYSEATSTIMESMLQDAVKSQKTSKFYGNLQTI NPSLATNVQWAGKTGTTDDYTDVWMMLSTPSVTLGGWAGHDDNSPMTSNSGYINNAAYIAQLVNAINAADPNIFGPGQKF TDPNTDPNVTKSKVLVSTGEKPGKVTVKLANGKTQEVNLGGETTTSFWATKAGAPTTTYDFSIGGSASDIAAGWKKILPS FNFSQTSSSKSN >Mature_812_residues MKKDSIDSQEEIRARLKEKMDNKRRKQSNSSRKSPKKNNNDSDDRSILSITFKVLRGLSVVFGIVFVLVGVFGAATGVGY FARLVEQTKIPPKAEMLSKINDIHGVSVINYSNGQPISDISSDLIRVTVKSDDISANVKNALIATEDDSFKTNKGVVPKA VIRGIVGSIGGGTSSGGSTLTQQLIKQQVLGDSVTFQRKASEIVYALKLNNYLTKDQILTDYLNVSPFGRNNKGQNIAGV QEAALGIFGKSAKDLTIPEAAFIAGLPQSPIVYSPYSADGSLKSKENMSYGLERQKEVLFYLYRGGYISEADYKKYVAYD ISKEFLQPGVAESQEHGYLYNVVYNEAITDIYNYLIKRDKVSATDLGNDSTKKRYQELAEQSLQNGGYTVTTTVNQTVYD AMQKAVTDYNGLMQDGTGTIQTGNVLMDNKTGAVYGFIGGLDFSQSQVNHAFDTKRSPGSSIKPILAYGPAIDMGLMGSA SVLSNYPAKYSSGQDIEHVGSTGTAMMPFSEALNVSYNIPAYWTYQTILNKGKSVEPYMTKMGYDIADYSVESLPLGGGV DPTVVQHTNGYQTLANGGKYEPWYIVDSIKDDTGNVIYQHKSTGGTQAYSEATSTIMESMLQDAVKSQKTSKFYGNLQTI NPSLATNVQWAGKTGTTDDYTDVWMMLSTPSVTLGGWAGHDDNSPMTSNSGYINNAAYIAQLVNAINAADPNIFGPGQKF TDPNTDPNVTKSKVLVSTGEKPGKVTVKLANGKTQEVNLGGETTTSFWATKAGAPTTTYDFSIGGSASDIAAGWKKILPS FNFSQTSSSKSN
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786343, Length=569, Percent_Identity=24.6045694200351, Blast_Score=114, Evalue=2e-26, Organism=Escherichia coli, GI1788867, Length=624, Percent_Identity=23.0769230769231, Blast_Score=111, Evalue=2e-25, Organism=Escherichia coli, GI87082258, Length=351, Percent_Identity=29.9145299145299, Blast_Score=109, Evalue=7e-25, Organism=Escherichia coli, GI1789601, Length=159, Percent_Identity=30.8176100628931, Blast_Score=67, Evalue=6e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.1.129; 3.4.-.- [C]
Molecular weight: Translated: 87846; Mature: 87846
Theoretical pI: Translated: 7.76; Mature: 7.76
Prosite motif: PS00318 HMG_COA_REDUCTASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKDSIDSQEEIRARLKEKMDNKRRKQSNSSRKSPKKNNNDSDDRSILSITFKVLRGLSV CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH VFGIVFVLVGVFGAATGVGYFARLVEQTKIPPKAEMLSKINDIHGVSVINYSNGQPISDI HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHH SSDLIRVTVKSDDISANVKNALIATEDDSFKTNKGVVPKAVIRGIVGSIGGGTSSGGSTL CCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHH TQQLIKQQVLGDSVTFQRKASEIVYALKLNNYLTKDQILTDYLNVSPFGRNNKGQNIAGV HHHHHHHHHHCCCCHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH QEAALGIFGKSAKDLTIPEAAFIAGLPQSPIVYSPYSADGSLKSKENMSYGLERQKEVLF HHHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHCHHHHHEEEE YLYRGGYISEADYKKYVAYDISKEFLQPGVAESQEHGYLYNVVYNEAITDIYNYLIKRDK EEECCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCC VSATDLGNDSTKKRYQELAEQSLQNGGYTVTTTVNQTVYDAMQKAVTDYNGLMQDGTGTI CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEE QTGNVLMDNKTGAVYGFIGGLDFSQSQVNHAFDTKRSPGSSIKPILAYGPAIDMGLMGSA EECCEEEECCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCH SVLSNYPAKYSSGQDIEHVGSTGTAMMPFSEALNVSYNIPAYWTYQTILNKGKSVEPYMT HHHHCCCCCCCCCCCHHHHCCCCCEECCHHHHCCEEECCCCEEEHHHHHCCCCCCCHHHH KMGYDIADYSVESLPLGGGVDPTVVQHTNGYQTLANGGKYEPWYIVDSIKDDTGNVIYQH HCCCCHHCCCHHCCCCCCCCCCCEEECCCCHHHHHCCCCCCCEEEEECCCCCCCCEEEEE KSTGGTQAYSEATSTIMESMLQDAVKSQKTSKFYGNLQTINPSLATNVQWAGKTGTTDDY CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHCCEEECCCCCCCCCC TDVWMMLSTPSVTLGGWAGHDDNSPMTSNSGYINNAAYIAQLVNAINAADPNIFGPGQKF CEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC TDPNTDPNVTKSKVLVSTGEKPGKVTVKLANGKTQEVNLGGETTTSFWATKAGAPTTTYD CCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCEEEECCCCCCCCEEEECCCCCCEEEE FSIGGSASDIAAGWKKILPSFNFSQTSSSKSN EECCCCHHHHHHHHHHHCCCCCCCCCCCCCCC >Mature Secondary Structure MKKDSIDSQEEIRARLKEKMDNKRRKQSNSSRKSPKKNNNDSDDRSILSITFKVLRGLSV CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH VFGIVFVLVGVFGAATGVGYFARLVEQTKIPPKAEMLSKINDIHGVSVINYSNGQPISDI HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHH SSDLIRVTVKSDDISANVKNALIATEDDSFKTNKGVVPKAVIRGIVGSIGGGTSSGGSTL CCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHH TQQLIKQQVLGDSVTFQRKASEIVYALKLNNYLTKDQILTDYLNVSPFGRNNKGQNIAGV HHHHHHHHHHCCCCHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH QEAALGIFGKSAKDLTIPEAAFIAGLPQSPIVYSPYSADGSLKSKENMSYGLERQKEVLF HHHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHCHHHHHEEEE YLYRGGYISEADYKKYVAYDISKEFLQPGVAESQEHGYLYNVVYNEAITDIYNYLIKRDK EEECCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCC VSATDLGNDSTKKRYQELAEQSLQNGGYTVTTTVNQTVYDAMQKAVTDYNGLMQDGTGTI CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCEE QTGNVLMDNKTGAVYGFIGGLDFSQSQVNHAFDTKRSPGSSIKPILAYGPAIDMGLMGSA EECCEEEECCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCH SVLSNYPAKYSSGQDIEHVGSTGTAMMPFSEALNVSYNIPAYWTYQTILNKGKSVEPYMT HHHHCCCCCCCCCCCHHHHCCCCCEECCHHHHCCEEECCCCEEEHHHHHCCCCCCCHHHH KMGYDIADYSVESLPLGGGVDPTVVQHTNGYQTLANGGKYEPWYIVDSIKDDTGNVIYQH HCCCCHHCCCHHCCCCCCCCCCCEEECCCCHHHHHCCCCCCCEEEEECCCCCCCCEEEEE KSTGGTQAYSEATSTIMESMLQDAVKSQKTSKFYGNLQTINPSLATNVQWAGKTGTTDDY CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHCCEEECCCCCCCCCC TDVWMMLSTPSVTLGGWAGHDDNSPMTSNSGYINNAAYIAQLVNAINAADPNIFGPGQKF CEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC TDPNTDPNVTKSKVLVSTGEKPGKVTVKLANGKTQEVNLGGETTTSFWATKAGAPTTTYD CCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCEEEECCCCCCCCEEEECCCCCCEEEE FSIGGSASDIAAGWKKILPSFNFSQTSSSKSN EECCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA