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The map label for this gene is murA1 [H]

Identifier: 125623197

GI number: 125623197

Start: 315003

End: 316265

Strand: Direct

Name: murA1 [H]

Synonym: llmg_0326

Alternate gene names: 125623197

Gene position: 315003-316265 (Clockwise)

Preceding gene: 125623196

Following gene: 125623198

Centisome position: 12.45

GC content: 39.51

Gene sequence:

>1263_bases
ATGAAAAAAATAGTAATTAATGGTGGGAAGCGTATCTCTGGAACAATTCCAATTTCTGGAGCAAAAAATTCAGTGGTTGC
TTTAATTCCTGCAACCATTCTAGCTAATGATATTGTTACTCTGGAAGGAGTTCCAGATATTTCTGATGTCGCAAGTTTAG
TCGAAATTATGGAAATTATGGGAGCAAAAATTGAGCGAAATCTTGAAGAAGGTCGACTTGTGATTGATACACGTAGTGTC
GTTTCACGTCCTCTGCCTTATGGAAAGATTAATTCTTTGCGTGCTTCTTATTATTTCAATGGTGCACTTTTGGGTCGTTT
TGGACAAGCGACAGTTGGCTTGCCCGGAGGATGTGATTTAGGTCCTCGTCCAACCGATTTACATGATAAAGCCTTTAAAG
CTTTAGGGGCTAAGAAGATTCAAGAAGAAGCTGAGCACTTAGAAGTGATTGGTGATTCATTAGTTGGAACAACCATTTAT
ATGGACGTTGTTTCCGTTGGAGCAACCATCAATACGATGCTTGCTGCTAGTCGTGCAAAAGGTGTAACTGTAATTGAAAA
TGCCGCACGTGAGCCTGAAATTATTGATGTGGCAACCCTTCTTAATAACATGGGGGCAAAAGTTCGTGGTGCTGGAACAG
ATATTATCCGTATCACTGGGATAGATGAAATGCACGGAGCTCAACATACGGTAATTCCTGACCGAATTGAGGCTGGAACT
TACCTTGCTTTAGCTGCTGCGATGGGTGATGGGGTTATTATTGAAAATGTCATCTATGAACATTTGGAATCTTTCATTGC
TAAGCTTGAAGAAATGGGCGTACGTTTGACGATTCGTGAAGACAGCATTGAAGTTCATAAATCTGAAAATTTAAAATCAG
TTAATATTACCTCTGTTCCTTACCCAGGATTTGCGACTGATTTGCAACAACCAATTACGCCACTGTTGTTAAAAGCAAAA
GGTCGTGGTTCGATTGTTGATACGATTTATCAAAAACGTGTTAACCACGTACCTGAATTAGCGCGTATGGGTGCTAATAT
TTCTGTTTTGGATGATAGAATTATTTATGACGCTCCGAATGAGTTAACTGGAAGCTGTGTTCAAGCAACAGATTTACGTG
CTGGTGCGGCTCTGGTTACTGCTGGAATTATTGCCAGTGGAACTACTAAAATTTCTAATATTGAGTTTATCCTACGAGGC
TATGATCATATCATTGAAAAATTGACTGCTGTTGGTGTAGATATTCAATTGATTGAAGAGTGA

Upstream 100 bases:

>100_bases
GTCTATGAAAAACTACTATAAAATGTTAAAATAGAGAGCGGTTCTTAAAAAAATAATTTTTTTAAGACAATAAAAATGTG
AAAAGTGATTTTGAAATAAT

Downstream 100 bases:

>100_bases
CAAAATAGATTTATTTGCGTATATACTAATGAGAAAGGATATAAGATGGCTGATAAATTAAAGTTTGAAATCATTGAAGA
ACTTATCGTTCTCTCTGAAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDIVTLEGVPDISDVASLVEIMEIMGAKIERNLEEGRLVIDTRSV
VSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDLGPRPTDLHDKAFKALGAKKIQEEAEHLEVIGDSLVGTTIY
MDVVSVGATINTMLAASRAKGVTVIENAAREPEIIDVATLLNNMGAKVRGAGTDIIRITGIDEMHGAQHTVIPDRIEAGT
YLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVRLTIREDSIEVHKSENLKSVNITSVPYPGFATDLQQPITPLLLKAK
GRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAPNELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILRG
YDHIIEKLTAVGVDIQLIEE

Sequences:

>Translated_420_residues
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDIVTLEGVPDISDVASLVEIMEIMGAKIERNLEEGRLVIDTRSV
VSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDLGPRPTDLHDKAFKALGAKKIQEEAEHLEVIGDSLVGTTIY
MDVVSVGATINTMLAASRAKGVTVIENAAREPEIIDVATLLNNMGAKVRGAGTDIIRITGIDEMHGAQHTVIPDRIEAGT
YLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVRLTIREDSIEVHKSENLKSVNITSVPYPGFATDLQQPITPLLLKAK
GRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAPNELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILRG
YDHIIEKLTAVGVDIQLIEE
>Mature_420_residues
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDIVTLEGVPDISDVASLVEIMEIMGAKIERNLEEGRLVIDTRSV
VSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDLGPRPTDLHDKAFKALGAKKIQEEAEHLEVIGDSLVGTTIY
MDVVSVGATINTMLAASRAKGVTVIENAAREPEIIDVATLLNNMGAKVRGAGTDIIRITGIDEMHGAQHTVIPDRIEAGT
YLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVRLTIREDSIEVHKSENLKSVNITSVPYPGFATDLQQPITPLLLKAK
GRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAPNELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILRG
YDHIIEKLTAVGVDIQLIEE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=42.2802850356295, Blast_Score=322, Evalue=4e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44889; Mature: 44889

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDIVTLEGVPDISDVASLVEIMEIM
CCEEEEECCCEEEEEEECCCCCCCEEEEEHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
GAKIERNLEEGRLVIDTRSVVSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDL
HHHHHCCHHCCEEEEEEHHHHHCCCCCCCHHCEEEEEEECCHHCCCCCCCEECCCCCCCC
GPRPTDLHDKAFKALGAKKIQEEAEHLEVIGDSLVGTTIYMDVVSVGATINTMLAASRAK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC
GVTVIENAAREPEIIDVATLLNNMGAKVRGAGTDIIRITGIDEMHGAQHTVIPDRIEAGT
CCEEEHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCCCCCCCCCHHCCCH
YLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVRLTIREDSIEVHKSENLKSVNITSVP
HEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCEEEEECCC
YPGFATDLQQPITPLLLKAKGRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAPN
CCCCHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCEEEECCEEEECCCC
ELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILRGYDHIIEKLTAVGVDIQLIEE
CCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure
MKKIVINGGKRISGTIPISGAKNSVVALIPATILANDIVTLEGVPDISDVASLVEIMEIM
CCEEEEECCCEEEEEEECCCCCCCEEEEEHHHHHHCCCEEECCCCCHHHHHHHHHHHHHH
GAKIERNLEEGRLVIDTRSVVSRPLPYGKINSLRASYYFNGALLGRFGQATVGLPGGCDL
HHHHHCCHHCCEEEEEEHHHHHCCCCCCCHHCEEEEEEECCHHCCCCCCCEECCCCCCCC
GPRPTDLHDKAFKALGAKKIQEEAEHLEVIGDSLVGTTIYMDVVSVGATINTMLAASRAK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCC
GVTVIENAAREPEIIDVATLLNNMGAKVRGAGTDIIRITGIDEMHGAQHTVIPDRIEAGT
CCEEEHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCCCCCCCCCHHCCCH
YLALAAAMGDGVIIENVIYEHLESFIAKLEEMGVRLTIREDSIEVHKSENLKSVNITSVP
HEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCEEEEECCC
YPGFATDLQQPITPLLLKAKGRGSIVDTIYQKRVNHVPELARMGANISVLDDRIIYDAPN
CCCCHHHHHCCCCHHEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCEEEECCEEEECCCC
ELTGSCVQATDLRAGAALVTAGIIASGTTKISNIEFILRGYDHIIEKLTAVGVDIQLIEE
CCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]